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The map label for this gene is ruvB

Identifier: 119774974

GI number: 119774974

Start: 2240347

End: 2241351

Strand: Reverse

Name: ruvB

Synonym: Sama_1839

Alternate gene names: 119774974

Gene position: 2241351-2240347 (Counterclockwise)

Preceding gene: 119774975

Following gene: 119774973

Centisome position: 52.05

GC content: 56.12

Gene sequence:

>1005_bases
ATGATTGAAGCCGACCGGCTTATTCAGCCCCAGGATCTGGGTCAGGAAGATGTGATTGACCGCGCCATGCGGCCAAAATT
ACTCGACGAATACACGGGGCAGGACGATACCCGCGCCCAGCTTAAAGTCTTTATTGAGGCGGCTAAAAAGCGCGGCGAAG
CCCTGGATCATATGCTTATCTACGGCCCACCAGGCCTGGGTAAAACCACCCTGGCCAATATCGTTGCCAACGAAATGGGG
GTGAACATCAAGTCCACCTCCGGGCCTGTGCTGGAAAAGGCAGGCGATTTGGCGGCCCTGCTCACCAATCTTGAAGAAGG
TGACGTGCTCTTTATCGATGAAATCCACCGCTTAAGCCCTGTGGTGGAGGAAATCCTCTATCCGGCGATGGAAGACTATC
AGCTGGATATCATGATAGGTGAGGGGCCCGCTGCACGCTCTATCAAGCTGGATTTGCCGCCTTTTACCCTGGTGGGCGCA
ACAACCCGAGCAGGTTCACTCACATCACCGCTGCGGGCCCGTTTCGGCATTCCGCTGCGGCTTGAGTTTTACAATGTCCG
TGACCTGTCATCCATTGTGGCGCGCTCCGCCAAGGTGATGGATGTGCCCATGGATGAAGGTGGCGCCGAAGAGATTGCCC
GCCGCAGCCGCGGTACTCCCCGTATCGCCAACCGGCTGCTTCGCCGGGTGCGGGACTTTGCTGAAGTGAAGCATGATGGC
GCAATCAGCCGTGCGGTGGCTCAGTCAGCACTGGATTTATTGGATGTGGACAGCGAAGGCTTTGATTACATGGACCGCAA
GCTGCTGCTGGCGATTATCGACAAGTTTATGGGAGGACCTGTGGGTCTGGATAACCTTGCCGCCGCCATCGGTGAGGAAC
GTGAAACCATAGAAGATGTGCTTGAGCCATTTCTTATTCAGCAGGGGTTTGTGCAGCGCACACCAAGGGGGCGGATTGCC
ACGGCCCGTGCCTACAGCCATTTTGACCTTATCAAACCAGATTGA

Upstream 100 bases:

>100_bases
CAAGCAAAGCCGTATCCAGTGCCTTCCAGGAGGGCATGGATCCCGAGCAGCTTATCAAGGCTGCACTTAAGTCCATGCTC
TAAGGTGAAAGGGGAATACC

Downstream 100 bases:

>100_bases
CTAAATCCGCTAAACCACTGCTTAAAAAAGAGACCCCTGGGGTCTCTTTTTTTATGGGACAAGGGTTTATGTCCTTCGCT
ATTCGTTAACAGACTCGGTG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIEADRLIQPQDLGQEDVIDRAMRPKLLDEYTGQDDTRAQLKVFIEAAKKRGEALDHMLIYGPPGLGKTTLANIVANEMG
VNIKSTSGPVLEKAGDLAALLTNLEEGDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGSLTSPLRARFGIPLRLEFYNVRDLSSIVARSAKVMDVPMDEGGAEEIARRSRGTPRIANRLLRRVRDFAEVKHDG
AISRAVAQSALDLLDVDSEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFVQRTPRGRIA
TARAYSHFDLIKPD

Sequences:

>Translated_334_residues
MIEADRLIQPQDLGQEDVIDRAMRPKLLDEYTGQDDTRAQLKVFIEAAKKRGEALDHMLIYGPPGLGKTTLANIVANEMG
VNIKSTSGPVLEKAGDLAALLTNLEEGDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGSLTSPLRARFGIPLRLEFYNVRDLSSIVARSAKVMDVPMDEGGAEEIARRSRGTPRIANRLLRRVRDFAEVKHDG
AISRAVAQSALDLLDVDSEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFVQRTPRGRIA
TARAYSHFDLIKPD
>Mature_334_residues
MIEADRLIQPQDLGQEDVIDRAMRPKLLDEYTGQDDTRAQLKVFIEAAKKRGEALDHMLIYGPPGLGKTTLANIVANEMG
VNIKSTSGPVLEKAGDLAALLTNLEEGDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGSLTSPLRARFGIPLRLEFYNVRDLSSIVARSAKVMDVPMDEGGAEEIARRSRGTPRIANRLLRRVRDFAEVKHDG
AISRAVAQSALDLLDVDSEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFVQRTPRGRIA
TARAYSHFDLIKPD

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=78.1437125748503, Blast_Score=530, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_SHEAM (A1S6N8)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927714.1
- ProteinModelPortal:   A1S6N8
- SMR:   A1S6N8
- STRING:   A1S6N8
- GeneID:   4604089
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1839
- NMPDR:   fig|326297.7.peg.1731
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   A1S6N8
- ProtClustDB:   PRK00080
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 36833; Mature: 36833

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEADRLIQPQDLGQEDVIDRAMRPKLLDEYTGQDDTRAQLKVFIEAAKKRGEALDHMLI
CCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEE
YGPPGLGKTTLANIVANEMGVNIKSTSGPVLEKAGDLAALLTNLEEGDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
VVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGSLTSPLRARFGIPLR
HHHHHHHCCCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHCCCCEE
LEFYNVRDLSSIVARSAKVMDVPMDEGGAEEIARRSRGTPRIANRLLRRVRDFAEVKHDG
EEEECHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCH
AISRAVAQSALDLLDVDSEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHH
LEPFLIQQGFVQRTPRGRIATARAYSHFDLIKPD
HHHHHHHHHHHHCCCCCCEEEHHHHHHCCCCCCC
>Mature Secondary Structure
MIEADRLIQPQDLGQEDVIDRAMRPKLLDEYTGQDDTRAQLKVFIEAAKKRGEALDHMLI
CCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEE
YGPPGLGKTTLANIVANEMGVNIKSTSGPVLEKAGDLAALLTNLEEGDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
VVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGSLTSPLRARFGIPLR
HHHHHHHCCCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHCCCCEE
LEFYNVRDLSSIVARSAKVMDVPMDEGGAEEIARRSRGTPRIANRLLRRVRDFAEVKHDG
EEEECHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCH
AISRAVAQSALDLLDVDSEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHH
LEPFLIQQGFVQRTPRGRIATARAYSHFDLIKPD
HHHHHHHHHHHHCCCCCCEEEHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA