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The map label for this gene is serC

Identifier: 119774867

GI number: 119774867

Start: 2121128

End: 2122222

Strand: Direct

Name: serC

Synonym: Sama_1732

Alternate gene names: 119774867

Gene position: 2121128-2122222 (Clockwise)

Preceding gene: 119774866

Following gene: 119774869

Centisome position: 49.26

GC content: 51.87

Gene sequence:

>1095_bases
GTGAGCGCGGTTTATAATTTCTGTGCCGGACCGGCGATGTTGCCGGCTGCCGTGATGAAGAAGGCACAAGCTGAGTTACT
GGACTGGAATGGGCAGGGGGTGTCTGTGATGGAGGTGAGCCACCGTGGTGCGCCTTTCATTCAACTGGCCAAAGACTCTG
AAGCCGATTTGCGCGAGCTGATGAATATCCCCGACAACTACCATGTGCTCTTTATGCATGGCGGTGGTCGTGGTCAGTTT
TCTGCTGTTGTGAATAATTTTTTAGGTGATAACGGCAAAGCCCTGTATCTCGTCAGCGGTCAATGGTCAAAAGCCGCTAC
TGAAGAAGCCAAAAAACTCGCTGGCGACAACAGTATCGATGTCATCAATGTCGTCGAAAAAGTAAATGGATTGAACAAGG
TAGTGATTCCAGCGCTCAGCGGCAACGGCAGCGAGTACCGCTATTTACACTATTGCCCCAATGAGACAGTGGATGGCATC
GAAATTTTTGATGACATTGACAGTCCCTGGCCAATTGTGGCGGATATGTCGTCCAACATCATGTCCCGCGAGATTGATGT
CAGCCGTTTTGCGCTTATCTATGCCGGCGCTCAAAAAAACATTGGTCCATCGGGTTTGTCTATCGTGATTGTCCGTAAAG
ACATGCTGGAACTGCCGCAGCTGACTCAGTCTTCCATCATGGATTATCGCCTGACCGCCGAAAACGACTCGATGTACAAT
ACGCCGCCGACCTTTGCCTGGTACCTGGCCGCCGAAGTGTTCAAGTGGCTCAAGTCTGTGGGAGGCATAAAGGGTATGGC
CGAGGTAAACGCCGAAAAGGCGCGCCGTCTCTACGCCTGTATCGACAGTCTGGATTTTTACAAAAACGGGGTGGCGCCGC
AAAACCGCTCGCAGATGAATGTCACCTTCCAGCTCGCCGATGAGTCGCTGGATAAAGACTTCCTTAAAGAAGCGGAAGCG
CTTGGTCTTGTTGCGCTCAAAGGCCACCGTATTGTGGGCGGTATGCGCGCCAGTATCTACAACGCCATGCCATTGGAAGG
GGTTGATGCACTGGTGAGCTTTATGCGCTCATTTGCTGCCAAGCACAGCAGCTAA

Upstream 100 bases:

>100_bases
CGCCCAATGGGCGCTCGTTTTTTTTGCCAAACAGATTTTTTATTTTTCCAAACGTGTGACTACCAATGGGTATCACCGAA
GGCTAGCAAGGAGATCATGA

Downstream 100 bases:

>100_bases
TCAGTTTTAATCGCGAATAAAAAAGGACTGCCTCGGCAGTCCTTTTTGTTATCGAGCTCTTTGTTGGTTAAAGCACGGCG
ATAATGGATTTGGCCAGATA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSAVYNFCAGPAMLPAAVMKKAQAELLDWNGQGVSVMEVSHRGAPFIQLAKDSEADLRELMNIPDNYHVLFMHGGGRGQF
SAVVNNFLGDNGKALYLVSGQWSKAATEEAKKLAGDNSIDVINVVEKVNGLNKVVIPALSGNGSEYRYLHYCPNETVDGI
EIFDDIDSPWPIVADMSSNIMSREIDVSRFALIYAGAQKNIGPSGLSIVIVRKDMLELPQLTQSSIMDYRLTAENDSMYN
TPPTFAWYLAAEVFKWLKSVGGIKGMAEVNAEKARRLYACIDSLDFYKNGVAPQNRSQMNVTFQLADESLDKDFLKEAEA
LGLVALKGHRIVGGMRASIYNAMPLEGVDALVSFMRSFAAKHSS

Sequences:

>Translated_364_residues
MSAVYNFCAGPAMLPAAVMKKAQAELLDWNGQGVSVMEVSHRGAPFIQLAKDSEADLRELMNIPDNYHVLFMHGGGRGQF
SAVVNNFLGDNGKALYLVSGQWSKAATEEAKKLAGDNSIDVINVVEKVNGLNKVVIPALSGNGSEYRYLHYCPNETVDGI
EIFDDIDSPWPIVADMSSNIMSREIDVSRFALIYAGAQKNIGPSGLSIVIVRKDMLELPQLTQSSIMDYRLTAENDSMYN
TPPTFAWYLAAEVFKWLKSVGGIKGMAEVNAEKARRLYACIDSLDFYKNGVAPQNRSQMNVTFQLADESLDKDFLKEAEA
LGLVALKGHRIVGGMRASIYNAMPLEGVDALVSFMRSFAAKHSS
>Mature_363_residues
SAVYNFCAGPAMLPAAVMKKAQAELLDWNGQGVSVMEVSHRGAPFIQLAKDSEADLRELMNIPDNYHVLFMHGGGRGQFS
AVVNNFLGDNGKALYLVSGQWSKAATEEAKKLAGDNSIDVINVVEKVNGLNKVVIPALSGNGSEYRYLHYCPNETVDGIE
IFDDIDSPWPIVADMSSNIMSREIDVSRFALIYAGAQKNIGPSGLSIVIVRKDMLELPQLTQSSIMDYRLTAENDSMYNT
PPTFAWYLAAEVFKWLKSVGGIKGMAEVNAEKARRLYACIDSLDFYKNGVAPQNRSQMNVTFQLADESLDKDFLKEAEAL
GLVALKGHRIVGGMRASIYNAMPLEGVDALVSFMRSFAAKHSS

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily

Homologues:

Organism=Homo sapiens, GI17402893, Length=369, Percent_Identity=44.1734417344173, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI10863955, Length=365, Percent_Identity=38.9041095890411, Blast_Score=244, Evalue=9e-65,
Organism=Escherichia coli, GI1787136, Length=364, Percent_Identity=56.8681318681319, Blast_Score=418, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17506897, Length=368, Percent_Identity=41.5760869565217, Blast_Score=276, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6324758, Length=395, Percent_Identity=39.2405063291139, Blast_Score=259, Evalue=6e-70,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=44.6280991735537, Blast_Score=306, Evalue=2e-83,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SERC_SHEAM (A1S6D1)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927607.1
- ProteinModelPortal:   A1S6D1
- SMR:   A1S6D1
- STRING:   A1S6D1
- GeneID:   4603982
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1732
- NMPDR:   fig|326297.7.peg.1636
- eggNOG:   COG1932
- HOGENOM:   HBG289982
- OMA:   TFAWYLA
- PhylomeDB:   A1S6D1
- ProtClustDB:   PRK05355
- GO:   GO:0005737
- HAMAP:   MF_00160
- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000525
- TIGRFAMs:   TIGR01364

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.52

Molecular weight: Translated: 39868; Mature: 39737

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: BINDING 42-42 BINDING 102-102 BINDING 156-156 BINDING 175-175 BINDING 198-198

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVYNFCAGPAMLPAAVMKKAQAELLDWNGQGVSVMEVSHRGAPFIQLAKDSEADLREL
CCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCCHHHHHHH
MNIPDNYHVLFMHGGGRGQFSAVVNNFLGDNGKALYLVSGQWSKAATEEAKKLAGDNSID
HCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCH
VINVVEKVNGLNKVVIPALSGNGSEYRYLHYCPNETVDGIEIFDDIDSPWPIVADMSSNI
HHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCCCCCCHHHHHCCCCCCCEEECCCCCH
MSREIDVSRFALIYAGAQKNIGPSGLSIVIVRKDMLELPQLTQSSIMDYRLTAENDSMYN
HHHCCCHHEEEEEEECCCCCCCCCCCEEEEEEHHHHHCHHHHHHHHHEEEEEECCCCCCC
TPPTFAWYLAAEVFKWLKSVGGIKGMAEVNAEKARRLYACIDSLDFYKNGVAPQNRSQMN
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
VTFQLADESLDKDFLKEAEALGLVALKGHRIVGGMRASIYNAMPLEGVDALVSFMRSFAA
EEEEECCCCCCHHHHHHHHHCCEEEECCCEEECCHHHHHHCCCCCCHHHHHHHHHHHHHH
KHSS
CCCC
>Mature Secondary Structure 
SAVYNFCAGPAMLPAAVMKKAQAELLDWNGQGVSVMEVSHRGAPFIQLAKDSEADLREL
CCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCCHHHHHHH
MNIPDNYHVLFMHGGGRGQFSAVVNNFLGDNGKALYLVSGQWSKAATEEAKKLAGDNSID
HCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCH
VINVVEKVNGLNKVVIPALSGNGSEYRYLHYCPNETVDGIEIFDDIDSPWPIVADMSSNI
HHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCCCCCCHHHHHCCCCCCCEEECCCCCH
MSREIDVSRFALIYAGAQKNIGPSGLSIVIVRKDMLELPQLTQSSIMDYRLTAENDSMYN
HHHCCCHHEEEEEEECCCCCCCCCCCEEEEEEHHHHHCHHHHHHHHHEEEEEECCCCCCC
TPPTFAWYLAAEVFKWLKSVGGIKGMAEVNAEKARRLYACIDSLDFYKNGVAPQNRSQMN
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
VTFQLADESLDKDFLKEAEALGLVALKGHRIVGGMRASIYNAMPLEGVDALVSFMRSFAA
EEEEECCCCCCHHHHHHHHHCCEEEECCCEEECCHHHHHHCCCCCCHHHHHHHHHHHHHH
KHSS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA