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The map label for this gene is aroA

Identifier: 119774869

GI number: 119774869

Start: 2123951

End: 2125237

Strand: Direct

Name: aroA

Synonym: Sama_1734

Alternate gene names: 119774869

Gene position: 2123951-2125237 (Clockwise)

Preceding gene: 119774867

Following gene: 119774870

Centisome position: 49.32

GC content: 54.86

Gene sequence:

>1287_bases
ATGGACCAATTACGTCTTGAGCCCGTATCCCGGGTCAACGGGGTGGTTAACATCCCCGGTTCCAAAAGCATCTCCAACCG
CGCATTGCTGTTGGCAACCCTGGCAAGTGGCGAAACCACTCTGGTAAATCTGCTGGATTCTGATGATATCCGCCATATGC
TAAACGCGCTCAAAAGCCTGGGCGTTAATTTCACCTTGTCTGATGACAAGACGGTGTGTACGCTCAATGGCCTCGGTGGT
CCTATCCAAACAGATAAGGCCTTTGAGCTGTTTTTAGGTAACGCCGGCACGGCGATGCGACCCCTGTGCGCCGCGCTGAC
TCTGGGGACCGGGGAATTTACCCTGACCGGTGAGCCGCGCATGGAAGAGCGCCCCATTGGCGATCTGGTGGATGCGCTGC
GTCAGCTTGGCGCCGATATCCGTTACCTTAAAAATGATGGCTTCCCGCCACTCACCATCAATGCCACCGGGCTTGCGGGC
GGCGTGGTGGAAATAGATGGTAGCCTCTCCAGCCAGTTTCTGACTGCGCTGCTCATGGTGGCACCCCTTGCCAAGGGAGC
TGTGACCATTGCCGTAAAAGGTGAGCTCGTTTCCAAACCTTACATCGATATCACCCTGGATTTGATGGCCAAATTTGGGG
TGACAGTCGTCAATGACAACTATCAGCGCTTCGAGATTGCATCAGGGCAACACTATGTGTCGCCCGGCAAGGTGCTGGTT
GAAGGGGACGCGTCATCTGCGTCTTACTTCCTTGCGGCCGGTGCTATTGGCGGCGGTGAAGTGAAAGTCACCGGCGTTGG
CCGTTTGGCGGTGCAGGGCGATGTGAAATTTGCCGATGCCCTGGCGGCTATGGGAGCAGATATTGAATGGGGCGAAGATT
ACATTATCGCCAGAGGCAGTAAGCTTCACGGTATCGACATGGACATGAACCACATTCCCGATGCGGCCATGACCATTGCC
ACCGCGGCGCTGTTTGCCGAAGGCACCACCCGGATGAGCAACATCTACAATTGGCGCATCAAGGAAACCGACCGTCTTGC
CGCCATGGCGACTGAGCTTCGAAAAGTCGGCGCCAAAGTGGAAGAGGGGCACGATTACATCCAGATCACACCGCCGGTCA
AACCAGTTCATGCCGAAATCGATACCTATAACGATCACCGCATGGCGATGTGTTTTTCACTGCTGGCGTTTGCCGATTGC
GGGGTGACCATTAACGATCCTGGCTGTACCTCAAAAACATTTCCGGATTATTTCAATCGCTTCGCTAACTTAGCTAAGCC
GGATTGA

Upstream 100 bases:

>100_bases
TTTTTCCTCAAACGTAACGCGGGGCTTACAGCGTTGTAGCGCAGCCTTGCCAACTTCGGCCAATCTGGCCTTCACTCGCT
TTTAATGAGAAGTACGAGAA

Downstream 100 bases:

>100_bases
GTGCTGTAAAAATGGGCTGTCGGAGGATAGCCCATTTTTTTGACAAAAATTCCCACGGATCTTTACGCGCCTTGATGTAT
AATGCCGCCCGCTCATTTTC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MDQLRLEPVSRVNGVVNIPGSKSISNRALLLATLASGETTLVNLLDSDDIRHMLNALKSLGVNFTLSDDKTVCTLNGLGG
PIQTDKAFELFLGNAGTAMRPLCAALTLGTGEFTLTGEPRMEERPIGDLVDALRQLGADIRYLKNDGFPPLTINATGLAG
GVVEIDGSLSSQFLTALLMVAPLAKGAVTIAVKGELVSKPYIDITLDLMAKFGVTVVNDNYQRFEIASGQHYVSPGKVLV
EGDASSASYFLAAGAIGGGEVKVTGVGRLAVQGDVKFADALAAMGADIEWGEDYIIARGSKLHGIDMDMNHIPDAAMTIA
TAALFAEGTTRMSNIYNWRIKETDRLAAMATELRKVGAKVEEGHDYIQITPPVKPVHAEIDTYNDHRMAMCFSLLAFADC
GVTINDPGCTSKTFPDYFNRFANLAKPD

Sequences:

>Translated_428_residues
MDQLRLEPVSRVNGVVNIPGSKSISNRALLLATLASGETTLVNLLDSDDIRHMLNALKSLGVNFTLSDDKTVCTLNGLGG
PIQTDKAFELFLGNAGTAMRPLCAALTLGTGEFTLTGEPRMEERPIGDLVDALRQLGADIRYLKNDGFPPLTINATGLAG
GVVEIDGSLSSQFLTALLMVAPLAKGAVTIAVKGELVSKPYIDITLDLMAKFGVTVVNDNYQRFEIASGQHYVSPGKVLV
EGDASSASYFLAAGAIGGGEVKVTGVGRLAVQGDVKFADALAAMGADIEWGEDYIIARGSKLHGIDMDMNHIPDAAMTIA
TAALFAEGTTRMSNIYNWRIKETDRLAAMATELRKVGAKVEEGHDYIQITPPVKPVHAEIDTYNDHRMAMCFSLLAFADC
GVTINDPGCTSKTFPDYFNRFANLAKPD
>Mature_428_residues
MDQLRLEPVSRVNGVVNIPGSKSISNRALLLATLASGETTLVNLLDSDDIRHMLNALKSLGVNFTLSDDKTVCTLNGLGG
PIQTDKAFELFLGNAGTAMRPLCAALTLGTGEFTLTGEPRMEERPIGDLVDALRQLGADIRYLKNDGFPPLTINATGLAG
GVVEIDGSLSSQFLTALLMVAPLAKGAVTIAVKGELVSKPYIDITLDLMAKFGVTVVNDNYQRFEIASGQHYVSPGKVLV
EGDASSASYFLAAGAIGGGEVKVTGVGRLAVQGDVKFADALAAMGADIEWGEDYIIARGSKLHGIDMDMNHIPDAAMTIA
TAALFAEGTTRMSNIYNWRIKETDRLAAMATELRKVGAKVEEGHDYIQITPPVKPVHAEIDTYNDHRMAMCFSLLAFADC
GVTINDPGCTSKTFPDYFNRFANLAKPD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=426, Percent_Identity=67.1361502347418, Blast_Score=575, Evalue=1e-165,
Organism=Saccharomyces cerevisiae, GI6320332, Length=447, Percent_Identity=38.4787472035794, Blast_Score=246, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_SHEAM (A1S6D3)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927609.1
- ProteinModelPortal:   A1S6D3
- SMR:   A1S6D3
- STRING:   A1S6D3
- GeneID:   4603984
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1734
- NMPDR:   fig|326297.7.peg.1638
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   GADIEWG
- PhylomeDB:   A1S6D3
- ProtClustDB:   PRK02427
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45649; Mature: 45649

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLRLEPVSRVNGVVNIPGSKSISNRALLLATLASGETTLVNLLDSDDIRHMLNALKSL
CCCCCCCCHHHCCCEEECCCCCCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHC
GVNFTLSDDKTVCTLNGLGGPIQTDKAFELFLGNAGTAMRPLCAALTLGTGEFTLTGEPR
CCEEEECCCCEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHEECCCCEEECCCCC
MEERPIGDLVDALRQLGADIRYLKNDGFPPLTINATGLAGGVVEIDGSLSSQFLTALLMV
CCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHH
APLAKGAVTIAVKGELVSKPYIDITLDLMAKFGVTVVNDNYQRFEIASGQHYVSPGKVLV
HHHCCCEEEEEEECCCCCCCEEEEEHHHHHHCCCEEECCCCEEEEEECCCEEECCCCEEE
EGDASSASYFLAAGAIGGGEVKVTGVGRLAVQGDVKFADALAAMGADIEWGEDYIIARGS
ECCCCCCEEEEEEECCCCCEEEEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCEEEECCC
KLHGIDMDMNHIPDAAMTIATAALFAEGTTRMSNIYNWRIKETDRLAAMATELRKVGAKV
EEEEECCCHHHCCHHHHHHHHHHHHHCCCHHHHHEEEEEECCHHHHHHHHHHHHHHCCCC
EEGHDYIQITPPVKPVHAEIDTYNDHRMAMCFSLLAFADCGVTINDPGCTSKTFPDYFNR
CCCCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHH
FANLAKPD
HHHCCCCC
>Mature Secondary Structure
MDQLRLEPVSRVNGVVNIPGSKSISNRALLLATLASGETTLVNLLDSDDIRHMLNALKSL
CCCCCCCCHHHCCCEEECCCCCCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHC
GVNFTLSDDKTVCTLNGLGGPIQTDKAFELFLGNAGTAMRPLCAALTLGTGEFTLTGEPR
CCEEEECCCCEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHEECCCCEEECCCCC
MEERPIGDLVDALRQLGADIRYLKNDGFPPLTINATGLAGGVVEIDGSLSSQFLTALLMV
CCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHH
APLAKGAVTIAVKGELVSKPYIDITLDLMAKFGVTVVNDNYQRFEIASGQHYVSPGKVLV
HHHCCCEEEEEEECCCCCCCEEEEEHHHHHHCCCEEECCCCEEEEEECCCEEECCCCEEE
EGDASSASYFLAAGAIGGGEVKVTGVGRLAVQGDVKFADALAAMGADIEWGEDYIIARGS
ECCCCCCEEEEEEECCCCCEEEEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCEEEECCC
KLHGIDMDMNHIPDAAMTIATAALFAEGTTRMSNIYNWRIKETDRLAAMATELRKVGAKV
EEEEECCCHHHCCHHHHHHHHHHHHHCCCHHHHHEEEEEECCHHHHHHHHHHHHHHCCCC
EEGHDYIQITPPVKPVHAEIDTYNDHRMAMCFSLLAFADCGVTINDPGCTSKTFPDYFNR
CCCCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHH
FANLAKPD
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA