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The map label for this gene is celR [H]

Identifier: 119774791

GI number: 119774791

Start: 2019731

End: 2020831

Strand: Direct

Name: celR [H]

Synonym: Sama_1655

Alternate gene names: 119774791

Gene position: 2019731-2020831 (Clockwise)

Preceding gene: 119774790

Following gene: 119774794

Centisome position: 46.9

GC content: 54.41

Gene sequence:

>1101_bases
ATGAGCTTGCCGCTCTGTGTCGGGGCGGTGGCCAGTGGCCCGAGCAAATATAACAAGAGTCCTGTTATGGCGAGTAAAGC
GACCTCTATCGATATTGCCTATCGGGCGGGTGTGTCCCAGTCCACTGTGTCCCGCGCCCTGAGGGACAGCCCCTTGGTGA
GTCCGGAAACCAAGGAAAAAATCCGTGCCATTGCCCGCGAGCTTAACTACAAGGTAGATAAAAACGCCAGTAATCTGCGT
ACCCAAAACAGCCATACCCTGGCATTGCTGCTGTGTGAAGATCCCACCAACGACGACTCCCTGATTAATCCTTTCTTTTT
GTCGATGCTGGGCTCTATTACCCGGGCTACTGCAAAACAGGGCTACGATTTGTTGGTGTCTTTTCAGCAGCTTTCCAGCG
ATTGGCACGCCGACTATGAAGACAGCAACAAAGCAGACGGTATTATTCTGCTTGGCTACGGTGACTTTGTGGACTATGAG
CACAAGCTGGAGCGCTTGCTGGCCCAAAATACTCACTTTGTGATTTGGGGTGCTGAGCACAACAAGTCGACGGTGGCTTC
TGTGGGCTGTGATAATCAGCAGGGCGGCTTAATAGCCACCGAACACCTACTTTCCCTTGGTCGCAAATCCGTGGCATTTT
TGGGGGATGCCTCAAGCCACAGCCCTGAGTTTCGCGACCGCTACCTTGGCCATGTCAGGGCGCTTAAAGATGCGGGCCTT
GTGGCCGATAAGCGCTGCCAGGTGGATGCCATCAGCACTGAAAGTGCCGGCTTTGATGCGGCCAACAAGCTTATTCGCAA
GGGTGCCCAGTTTGATGCCATCTTTGCCGCCAGTGATTTGATTGCCATCGGGGCCATCAGGGCCCTGAAAGAAGCCGGGC
TCAGGGTGCCCGAAGACGTGGCTGTGGTGGGCTACGATGATATTCCGGTGGCGAGCTTTGCCAATCCGCCACTGACTACC
ATCAAGCAAAACACCCAACTTGCCGGTGAAATGTTGGTGGAAAGCCTGCTCAAACTCATTCACGGCGAGGCTGTGCCACC
ACGGTTAATCCCGACCAGCCTGGTGGTGAGGAAATCCTGTGGCATTGACCTTGGCGATTAA

Upstream 100 bases:

>100_bases
ATGGCTGGCAAGGGCATAGTGGCCGATGATGCTGATGATTTGCTCGATGAGCTGGGGATCTAAAGTCGCTTGCTATACAA
GGAATTGCACTTGATTTACC

Downstream 100 bases:

>100_bases
CGGCGCTGAATTATCGGCGCCAATACGCACGTCTGCTGCCGATAAACCCGTATTCTGAAAGTTTATCGAATAAGTTATCG
CAATAAAAAAGGAGCCCGGA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSLPLCVGAVASGPSKYNKSPVMASKATSIDIAYRAGVSQSTVSRALRDSPLVSPETKEKIRAIARELNYKVDKNASNLR
TQNSHTLALLLCEDPTNDDSLINPFFLSMLGSITRATAKQGYDLLVSFQQLSSDWHADYEDSNKADGIILLGYGDFVDYE
HKLERLLAQNTHFVIWGAEHNKSTVASVGCDNQQGGLIATEHLLSLGRKSVAFLGDASSHSPEFRDRYLGHVRALKDAGL
VADKRCQVDAISTESAGFDAANKLIRKGAQFDAIFAASDLIAIGAIRALKEAGLRVPEDVAVVGYDDIPVASFANPPLTT
IKQNTQLAGEMLVESLLKLIHGEAVPPRLIPTSLVVRKSCGIDLGD

Sequences:

>Translated_366_residues
MSLPLCVGAVASGPSKYNKSPVMASKATSIDIAYRAGVSQSTVSRALRDSPLVSPETKEKIRAIARELNYKVDKNASNLR
TQNSHTLALLLCEDPTNDDSLINPFFLSMLGSITRATAKQGYDLLVSFQQLSSDWHADYEDSNKADGIILLGYGDFVDYE
HKLERLLAQNTHFVIWGAEHNKSTVASVGCDNQQGGLIATEHLLSLGRKSVAFLGDASSHSPEFRDRYLGHVRALKDAGL
VADKRCQVDAISTESAGFDAANKLIRKGAQFDAIFAASDLIAIGAIRALKEAGLRVPEDVAVVGYDDIPVASFANPPLTT
IKQNTQLAGEMLVESLLKLIHGEAVPPRLIPTSLVVRKSCGIDLGD
>Mature_365_residues
SLPLCVGAVASGPSKYNKSPVMASKATSIDIAYRAGVSQSTVSRALRDSPLVSPETKEKIRAIARELNYKVDKNASNLRT
QNSHTLALLLCEDPTNDDSLINPFFLSMLGSITRATAKQGYDLLVSFQQLSSDWHADYEDSNKADGIILLGYGDFVDYEH
KLERLLAQNTHFVIWGAEHNKSTVASVGCDNQQGGLIATEHLLSLGRKSVAFLGDASSHSPEFRDRYLGHVRALKDAGLV
ADKRCQVDAISTESAGFDAANKLIRKGAQFDAIFAASDLIAIGAIRALKEAGLRVPEDVAVVGYDDIPVASFANPPLTTI
KQNTQLAGEMLVESLLKLIHGEAVPPRLIPTSLVVRKSCGIDLGD

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789068, Length=337, Percent_Identity=29.080118694362, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1790194, Length=320, Percent_Identity=30.625, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790369, Length=340, Percent_Identity=28.5294117647059, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786540, Length=345, Percent_Identity=31.304347826087, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1789202, Length=302, Percent_Identity=26.4900662251656, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788474, Length=342, Percent_Identity=29.2397660818713, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1787948, Length=352, Percent_Identity=25.5681818181818, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI48994940, Length=336, Percent_Identity=26.1904761904762, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787580, Length=333, Percent_Identity=28.8288288288288, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789456, Length=336, Percent_Identity=27.3809523809524, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790715, Length=318, Percent_Identity=27.0440251572327, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787906, Length=352, Percent_Identity=25.5681818181818, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790689, Length=338, Percent_Identity=25.4437869822485, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 39419; Mature: 39288

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPLCVGAVASGPSKYNKSPVMASKATSIDIAYRAGVSQSTVSRALRDSPLVSPETKEK
CCCCCCHHHHHCCCHHCCCCCCEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCHHHH
IRAIARELNYKVDKNASNLRTQNSHTLALLLCEDPTNDDSLINPFFLSMLGSITRATAKQ
HHHHHHHHCCCCCCCCHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHC
GYDLLVSFQQLSSDWHADYEDSNKADGIILLGYGDFVDYEHKLERLLAQNTHFVIWGAEH
CHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCC
NKSTVASVGCDNQQGGLIATEHLLSLGRKSVAFLGDASSHSPEFRDRYLGHVRALKDAGL
CCCEEEEECCCCCCCCCHHHHHHHHCCCHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
VADKRCQVDAISTESAGFDAANKLIRKGAQFDAIFAASDLIAIGAIRALKEAGLRVPEDV
CCCCCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
AVVGYDDIPVASFANPPLTTIKQNTQLAGEMLVESLLKLIHGEAVPPRLIPTSLVVRKSC
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHC
GIDLGD
CCCCCC
>Mature Secondary Structure 
SLPLCVGAVASGPSKYNKSPVMASKATSIDIAYRAGVSQSTVSRALRDSPLVSPETKEK
CCCCCHHHHHCCCHHCCCCCCEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCHHHH
IRAIARELNYKVDKNASNLRTQNSHTLALLLCEDPTNDDSLINPFFLSMLGSITRATAKQ
HHHHHHHHCCCCCCCCHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHC
GYDLLVSFQQLSSDWHADYEDSNKADGIILLGYGDFVDYEHKLERLLAQNTHFVIWGAEH
CHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCC
NKSTVASVGCDNQQGGLIATEHLLSLGRKSVAFLGDASSHSPEFRDRYLGHVRALKDAGL
CCCEEEEECCCCCCCCCHHHHHHHHCCCHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
VADKRCQVDAISTESAGFDAANKLIRKGAQFDAIFAASDLIAIGAIRALKEAGLRVPEDV
CCCCCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
AVVGYDDIPVASFANPPLTTIKQNTQLAGEMLVESLLKLIHGEAVPPRLIPTSLVVRKSC
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHC
GIDLGD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]