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The map label for this gene is dcp [H]

Identifier: 119774701

GI number: 119774701

Start: 1905406

End: 1907598

Strand: Reverse

Name: dcp [H]

Synonym: Sama_1564

Alternate gene names: 119774701

Gene position: 1907598-1905406 (Counterclockwise)

Preceding gene: 119774703

Following gene: 119774700

Centisome position: 44.3

GC content: 55.54

Gene sequence:

>2193_bases
ATGAAGGGACAAACCCTCAAGCCGCTTGTTGTGGCCATGACGCTGGCTCTGGGCCTCACGGCCTGCGGCAACGACGAAAA
CAAACAGACCGAGGTCGCCAATACGCCTGCTACCGTCGTTGAAGCCACCACCGGGGGTTCTGAGCAGGCAGCCATTACCG
CAGTCAACCCCTTCTTCGAACCCTACAATACCTATCAGGACATCCCGGCCTTCGAGAAAATCGAAGAGGCGCATTACCTG
CCTGCCTATGAAGAGGGCATCAAGCGTCAACAGGCTGAAATTCAGGCGATTATCGACAATCCCGACGCGCCCTCTTTCGC
CAACACCATCGAAGCCATGGAGCAAAGCGGCAAACTCATCAAACGCGTCTCTGCGGTGTTTTATAACCTGACCTCCGCCG
ACACCACCCCCGGCCTGCAGGCAATCTCCAAGGAAGTATCGCCCATGCTGTCGTCCGCCAGAGACGATATCTTCCTCAAC
GACAAGCTGTTTGCCCGGGTAAAAGCCGTGTATGAGCAGCGTGAAACCCTTGGGCTGAATACTGCCCAAAGTCGCCTTCT
GGAAGACACCTACAAGGCCTTCAGCCGCGGCGGTGCCAACCTTGATGAGGCCGGCAAAGCCAAGCTGCGTGAGCTGAACG
AAAAAATTGGCAAGTTGAGTCTGGAGTTTGGTGACAATGTCCTCGCCGAAACCAACAGTTTTGAACTGGTGGTGGAAAAC
AAAGACGATTTATCCGGTCTGCCACAGAGTGTGATTGATGTGGCTGCCGCTACCGCCAAGAGCCGTGGTAAAGAAGGCAA
ATGGGTGTTCACCACCTCACGCCCATCCATCACGCCGTTTTTGACCTACGCCGACAACCGCGAACTGCGCCAGCAGCTGT
ACACAGCCTATGTTGAGCGCGCCAATCACAACGATGCCCGCGACAACAAAAAGGCGCTGGCCGAAATTGCCGCCCTGCGC
GCCGAGCGTGCACAGCTTCTGGGGTATAAAACCCACGCCCACTACGTGCTGGAAGAAAACACGGCGAAAAACCCGGACAA
CGTTTACGCCCTGCTGGATAAGGTATGGCCTGCTGCCATCAATCAGGCCAAGTCTGAAGTAGCAGAGATGCAAAAGCTGA
TTGATGCTGAAGGTGGTAACTTCAAGCTGGCGCCATGGGACTGGGATTACTACGCCGACAAAATCCGCGTCGCCAAGTAC
AGCTTTAACGAACAGGATACCCGCCCCTACTTCTCACTCGATGCCACCATCGAAGGCGTGTTCTATACCGCCAACCGACT
GTTTGGCCTCACATTTAAAGAACGTAATGACCTGCCCAAGTACCATGAAGATGTGCGTACCTGGGAAGTGTTCGATAAAG
ACGGTAAGCTGCTGGCCATTTTCCTTGGCGACTACTACGTCCGCGACTCCAAGCGTGGCGGCGCCTGGATGAACGCTTAC
CGCTCACAGAGCGGCCTGGGTGATGAGCGTGTGGTGCCTATTATCGTTAACGTGCTCAACTACCCGCGCCCAACCGCGTC
TGAACCTTCGCTGCTGACCTTCGATGAAGCCAGCACCCTGTTCCACGAGTTTGGCCATGCCCTGCACGGTATGCTGTCGA
ATGTTGAGTACGAGGCTCAATCAGGCACCTCGGTACCAAGGGACTATGTGGAGTTTCCATCCCAGGTGACCGAAAACTGG
ATGACTCAGCCAGATGTGCTGGCTCAGTTTGCCAAACACTACAAAACCGGTGAAGTCATCCCCGATGAACTGGTCAAGAA
AATCCAGGCCGCCAGTAAGTTCAATCAGGGCTTTGCCACCGTTGAATACCTTGCCGCCACCAAGTTGGACCTCGACTGGC
ACACCCTTGAGACCAGCGAAGTGCAGGATGCCGCCGCTTTCGAAGCCGCCAGCCTCAAAAAGATGGGCCTGATTGACGAA
ATTGCGCCGCGTTACCGCTCAACCTACTTCAGCCATATCTTCTCCGGTGGTTACTCAGCCGGTTACTATGGCTACATCTG
GGCCGATATCCTCGGCGCGGATGCTTTTGAGGCCTTCCGCGAAAAGGGCATCTTCAACCAGGATACCGCCAACGCATTTC
GCGCCACTGTACTGTCTCAGGGCGGCAGCGAAGATCCGATGAAGCTGTACCGCGAATTCCGTGGCAAGGAAGCCAGCATC
GAGCCACTGCTCAAGAGCCGCGGCCTGCTGTAA

Upstream 100 bases:

>100_bases
ATGGCGGCCGCCTGAAACGGTAATATCTTACTGCTTAGGCGCAAAATTCAAACATACAGCACGCCGCCATCTCACACACA
CTCGATACAGGAAACGATCC

Downstream 100 bases:

>100_bases
TGGCAGTTGTTTGAATCTCATACTAAAAGCGCCCTCCGGGGCGCTTTTTTATTCACCGCTGATTGCGCCAAGCCCATCGT
TATATGTTCAGAAAACCGGC

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MKGQTLKPLVVAMTLALGLTACGNDENKQTEVANTPATVVEATTGGSEQAAITAVNPFFEPYNTYQDIPAFEKIEEAHYL
PAYEEGIKRQQAEIQAIIDNPDAPSFANTIEAMEQSGKLIKRVSAVFYNLTSADTTPGLQAISKEVSPMLSSARDDIFLN
DKLFARVKAVYEQRETLGLNTAQSRLLEDTYKAFSRGGANLDEAGKAKLRELNEKIGKLSLEFGDNVLAETNSFELVVEN
KDDLSGLPQSVIDVAAATAKSRGKEGKWVFTTSRPSITPFLTYADNRELRQQLYTAYVERANHNDARDNKKALAEIAALR
AERAQLLGYKTHAHYVLEENTAKNPDNVYALLDKVWPAAINQAKSEVAEMQKLIDAEGGNFKLAPWDWDYYADKIRVAKY
SFNEQDTRPYFSLDATIEGVFYTANRLFGLTFKERNDLPKYHEDVRTWEVFDKDGKLLAIFLGDYYVRDSKRGGAWMNAY
RSQSGLGDERVVPIIVNVLNYPRPTASEPSLLTFDEASTLFHEFGHALHGMLSNVEYEAQSGTSVPRDYVEFPSQVTENW
MTQPDVLAQFAKHYKTGEVIPDELVKKIQAASKFNQGFATVEYLAATKLDLDWHTLETSEVQDAAAFEAASLKKMGLIDE
IAPRYRSTYFSHIFSGGYSAGYYGYIWADILGADAFEAFREKGIFNQDTANAFRATVLSQGGSEDPMKLYREFRGKEASI
EPLLKSRGLL

Sequences:

>Translated_730_residues
MKGQTLKPLVVAMTLALGLTACGNDENKQTEVANTPATVVEATTGGSEQAAITAVNPFFEPYNTYQDIPAFEKIEEAHYL
PAYEEGIKRQQAEIQAIIDNPDAPSFANTIEAMEQSGKLIKRVSAVFYNLTSADTTPGLQAISKEVSPMLSSARDDIFLN
DKLFARVKAVYEQRETLGLNTAQSRLLEDTYKAFSRGGANLDEAGKAKLRELNEKIGKLSLEFGDNVLAETNSFELVVEN
KDDLSGLPQSVIDVAAATAKSRGKEGKWVFTTSRPSITPFLTYADNRELRQQLYTAYVERANHNDARDNKKALAEIAALR
AERAQLLGYKTHAHYVLEENTAKNPDNVYALLDKVWPAAINQAKSEVAEMQKLIDAEGGNFKLAPWDWDYYADKIRVAKY
SFNEQDTRPYFSLDATIEGVFYTANRLFGLTFKERNDLPKYHEDVRTWEVFDKDGKLLAIFLGDYYVRDSKRGGAWMNAY
RSQSGLGDERVVPIIVNVLNYPRPTASEPSLLTFDEASTLFHEFGHALHGMLSNVEYEAQSGTSVPRDYVEFPSQVTENW
MTQPDVLAQFAKHYKTGEVIPDELVKKIQAASKFNQGFATVEYLAATKLDLDWHTLETSEVQDAAAFEAASLKKMGLIDE
IAPRYRSTYFSHIFSGGYSAGYYGYIWADILGADAFEAFREKGIFNQDTANAFRATVLSQGGSEDPMKLYREFRGKEASI
EPLLKSRGLL
>Mature_730_residues
MKGQTLKPLVVAMTLALGLTACGNDENKQTEVANTPATVVEATTGGSEQAAITAVNPFFEPYNTYQDIPAFEKIEEAHYL
PAYEEGIKRQQAEIQAIIDNPDAPSFANTIEAMEQSGKLIKRVSAVFYNLTSADTTPGLQAISKEVSPMLSSARDDIFLN
DKLFARVKAVYEQRETLGLNTAQSRLLEDTYKAFSRGGANLDEAGKAKLRELNEKIGKLSLEFGDNVLAETNSFELVVEN
KDDLSGLPQSVIDVAAATAKSRGKEGKWVFTTSRPSITPFLTYADNRELRQQLYTAYVERANHNDARDNKKALAEIAALR
AERAQLLGYKTHAHYVLEENTAKNPDNVYALLDKVWPAAINQAKSEVAEMQKLIDAEGGNFKLAPWDWDYYADKIRVAKY
SFNEQDTRPYFSLDATIEGVFYTANRLFGLTFKERNDLPKYHEDVRTWEVFDKDGKLLAIFLGDYYVRDSKRGGAWMNAY
RSQSGLGDERVVPIIVNVLNYPRPTASEPSLLTFDEASTLFHEFGHALHGMLSNVEYEAQSGTSVPRDYVEFPSQVTENW
MTQPDVLAQFAKHYKTGEVIPDELVKKIQAASKFNQGFATVEYLAATKLDLDWHTLETSEVQDAAAFEAASLKKMGLIDE
IAPRYRSTYFSHIFSGGYSAGYYGYIWADILGADAFEAFREKGIFNQDTANAFRATVLSQGGSEDPMKLYREFRGKEASI
EPLLKSRGLL

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=603, Percent_Identity=28.8557213930348, Blast_Score=273, Evalue=6e-73,
Organism=Homo sapiens, GI14149738, Length=638, Percent_Identity=29.6238244514107, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI156105687, Length=671, Percent_Identity=24.441132637854, Blast_Score=174, Evalue=3e-43,
Organism=Escherichia coli, GI1787819, Length=681, Percent_Identity=43.1718061674009, Blast_Score=577, Evalue=1e-166,
Organism=Escherichia coli, GI1789913, Length=683, Percent_Identity=34.2606149341142, Blast_Score=409, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI71999758, Length=598, Percent_Identity=24.247491638796, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32565901, Length=610, Percent_Identity=21.6393442622951, Blast_Score=83, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319793, Length=607, Percent_Identity=31.3014827018122, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6322715, Length=469, Percent_Identity=24.9466950959488, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356111, Length=548, Percent_Identity=24.2700729927007, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI20129717, Length=451, Percent_Identity=26.3858093126386, Blast_Score=165, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 81532; Mature: 81532

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGQTLKPLVVAMTLALGLTACGNDENKQTEVANTPATVVEATTGGSEQAAITAVNPFFE
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCC
PYNTYQDIPAFEKIEEAHYLPAYEEGIKRQQAEIQAIIDNPDAPSFANTIEAMEQSGKLI
CCCHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHH
KRVSAVFYNLTSADTTPGLQAISKEVSPMLSSARDDIFLNDKLFARVKAVYEQRETLGLN
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHCCCC
TAQSRLLEDTYKAFSRGGANLDEAGKAKLRELNEKIGKLSLEFGDNVLAETNSFELVVEN
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEHCCCCCEEECCCCEEEEEEC
KDDLSGLPQSVIDVAAATAKSRGKEGKWVFTTSRPSITPFLTYADNRELRQQLYTAYVER
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHH
ANHNDARDNKKALAEIAALRAERAQLLGYKTHAHYVLEENTAKNPDNVYALLDKVWPAAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCEEHHEEEEEECCCCCCCHHHHHHHHHHHHHHH
NQAKSEVAEMQKLIDAEGGNFKLAPWDWDYYADKIRVAKYSFNEQDTRPYFSLDATIEGV
HHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHCCEEEEEECCCCCCCCCEEEECCEECEE
FYTANRLFGLTFKERNDLPKYHEDVRTWEVFDKDGKLLAIFLGDYYVRDSKRGGAWMNAY
EEECCHHEEEEECCCCCCCHHHHHHHHHEEECCCCCEEEEEECCEEEECCCCCCHHHHHH
RSQSGLGDERVVPIIVNVLNYPRPTASEPSLLTFDEASTLFHEFGHALHGMLSNVEYEAQ
HHCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
SGTSVPRDYVEFPSQVTENWMTQPDVLAQFAKHYKTGEVIPDELVKKIQAASKFNQGFAT
CCCCCCHHHHHCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHH
VEYLAATKLDLDWHTLETSEVQDAAAFEAASLKKMGLIDEIAPRYRSTYFSHIFSGGYSA
HHHHHHHEECCCCEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
GYYGYIWADILGADAFEAFREKGIFNQDTANAFRATVLSQGGSEDPMKLYREFRGKEASI
CCHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCH
EPLLKSRGLL
HHHHHHCCCC
>Mature Secondary Structure
MKGQTLKPLVVAMTLALGLTACGNDENKQTEVANTPATVVEATTGGSEQAAITAVNPFFE
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCC
PYNTYQDIPAFEKIEEAHYLPAYEEGIKRQQAEIQAIIDNPDAPSFANTIEAMEQSGKLI
CCCHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHH
KRVSAVFYNLTSADTTPGLQAISKEVSPMLSSARDDIFLNDKLFARVKAVYEQRETLGLN
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHCCCC
TAQSRLLEDTYKAFSRGGANLDEAGKAKLRELNEKIGKLSLEFGDNVLAETNSFELVVEN
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEHCCCCCEEECCCCEEEEEEC
KDDLSGLPQSVIDVAAATAKSRGKEGKWVFTTSRPSITPFLTYADNRELRQQLYTAYVER
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHH
ANHNDARDNKKALAEIAALRAERAQLLGYKTHAHYVLEENTAKNPDNVYALLDKVWPAAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCEEHHEEEEEECCCCCCCHHHHHHHHHHHHHHH
NQAKSEVAEMQKLIDAEGGNFKLAPWDWDYYADKIRVAKYSFNEQDTRPYFSLDATIEGV
HHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHCCEEEEEECCCCCCCCCEEEECCEECEE
FYTANRLFGLTFKERNDLPKYHEDVRTWEVFDKDGKLLAIFLGDYYVRDSKRGGAWMNAY
EEECCHHEEEEECCCCCCCHHHHHHHHHEEECCCCCEEEEEECCEEEECCCCCCHHHHHH
RSQSGLGDERVVPIIVNVLNYPRPTASEPSLLTFDEASTLFHEFGHALHGMLSNVEYEAQ
HHCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
SGTSVPRDYVEFPSQVTENWMTQPDVLAQFAKHYKTGEVIPDELVKKIQAASKFNQGFAT
CCCCCCHHHHHCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHH
VEYLAATKLDLDWHTLETSEVQDAAAFEAASLKKMGLIDEIAPRYRSTYFSHIFSGGYSA
HHHHHHHEECCCCEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
GYYGYIWADILGADAFEAFREKGIFNQDTANAFRATVLSQGGSEDPMKLYREFRGKEASI
CCHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCH
EPLLKSRGLL
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]