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The map label for this gene is serB [H]

Identifier: 119774115

GI number: 119774115

Start: 1182031

End: 1182981

Strand: Direct

Name: serB [H]

Synonym: Sama_0978

Alternate gene names: 119774115

Gene position: 1182031-1182981 (Clockwise)

Preceding gene: 119774113

Following gene: 119774116

Centisome position: 27.45

GC content: 57.83

Gene sequence:

>951_bases
ATGGAAAACACCTCTGAGTATGTGCTGCAAAACCGTCTTCACGCTTTGGCGACTTCCGGTCAGTGCCAATTGAGCCTGTA
TGAAGAAGGGCAAGCGCCACAAGGAGAGCGGGTGCGATTGGTGTGGGCAACCAAAGCAACTGAGGAGCTGATTTTTGCTC
GTCTGGCAGAGCTTAACTGCGCGGCTGCCCCCTTGGTGAGACGCAATGCCCTCAGCGGGCTGGAGTTGGTATCCAAGGGA
GAGGGTAATCTGTCGGCCGCATTTGATGGCATAGCCGGTCTTGAAGTTTTGCCTGTGACCGAATCCCTGCCGTCACTGCG
ACATCCGGGACTACTGGTGATGGATATGGACTCTACCGCTATCAAGATTGAATGTATCGATGAGCTTGCCGCCATGGCGG
GTGTGGGTGAAGCCGTCGCCGAAGTTACCGAGCGGGCCATGCAGGGTGAGTTGGATTTCAAGCAGAGCCTGCGTCAACGG
GTGGCCAAGCTTGCCGGTGCCGATGCCGGTATTATCGATACCCTGTGCGCCCGCTTGCCGCTGATGGACGGGTTGACCGA
GATGCTGGCCGAGCTAAAGGGGCATGGCTGGAAGCTGGTGGTCGCCTCAGGCGGCTTCACCCCTTTTGTGGGGCACCTCA
AGGCGACTCTTGGGTTGGACGCCGCCTTTGCCAACGAGCTGGTCATTGCCGATGGTAAGCTGGTGGGCGAAGTGACTGGC
ACAGTGGTGGATGCCAACTTCAAGGCCGATGTGGTCAGTCGCCTTGGCGATGAATACGGTATTAAAGACGGCCAACGCCT
CGCCATCGGCGATGGTGCCAACGATATACCCATGGTGCAGCGAGCCGACTTTGGTATCGCTTTTCATGCCAAACCCAAAC
TGGCCGCCGCTGCCGATGCCCGTATTCACACTCTGGATTTGCGGGTGCTTCCCTTCTTGCTGCAAGCGTGA

Upstream 100 bases:

>100_bases
TTAGTCCTTTAAGATACAACACCTTGACCCTTAAAAATTGACGCTTTGAGCTAATCATAAAGGATAAGGCATAAAGCGGA
TAGCCGGAGAACTCTCACCC

Downstream 100 bases:

>100_bases
ACTCCGAGGGTTTGAGTAATTGCTCTTGAGTTTTGTCTGTGCTCTGGTTTAGCCTGATTGAATATAGGCCCAGGCACAGA
CCTTGATAACCATGACAGCG

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MENTSEYVLQNRLHALATSGQCQLSLYEEGQAPQGERVRLVWATKATEELIFARLAELNCAAAPLVRRNALSGLELVSKG
EGNLSAAFDGIAGLEVLPVTESLPSLRHPGLLVMDMDSTAIKIECIDELAAMAGVGEAVAEVTERAMQGELDFKQSLRQR
VAKLAGADAGIIDTLCARLPLMDGLTEMLAELKGHGWKLVVASGGFTPFVGHLKATLGLDAAFANELVIADGKLVGEVTG
TVVDANFKADVVSRLGDEYGIKDGQRLAIGDGANDIPMVQRADFGIAFHAKPKLAAAADARIHTLDLRVLPFLLQA

Sequences:

>Translated_316_residues
MENTSEYVLQNRLHALATSGQCQLSLYEEGQAPQGERVRLVWATKATEELIFARLAELNCAAAPLVRRNALSGLELVSKG
EGNLSAAFDGIAGLEVLPVTESLPSLRHPGLLVMDMDSTAIKIECIDELAAMAGVGEAVAEVTERAMQGELDFKQSLRQR
VAKLAGADAGIIDTLCARLPLMDGLTEMLAELKGHGWKLVVASGGFTPFVGHLKATLGLDAAFANELVIADGKLVGEVTG
TVVDANFKADVVSRLGDEYGIKDGQRLAIGDGANDIPMVQRADFGIAFHAKPKLAAAADARIHTLDLRVLPFLLQA
>Mature_316_residues
MENTSEYVLQNRLHALATSGQCQLSLYEEGQAPQGERVRLVWATKATEELIFARLAELNCAAAPLVRRNALSGLELVSKG
EGNLSAAFDGIAGLEVLPVTESLPSLRHPGLLVMDMDSTAIKIECIDELAAMAGVGEAVAEVTERAMQGELDFKQSLRQR
VAKLAGADAGIIDTLCARLPLMDGLTEMLAELKGHGWKLVVASGGFTPFVGHLKATLGLDAAFANELVIADGKLVGEVTG
TVVDANFKADVVSRLGDEYGIKDGQRLAIGDGANDIPMVQRADFGIAFHAKPKLAAAADARIHTLDLRVLPFLLQA

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=182, Percent_Identity=32.967032967033, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1790849, Length=216, Percent_Identity=57.4074074074074, Blast_Score=239, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI115534454, Length=214, Percent_Identity=30.3738317757009, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534456, Length=214, Percent_Identity=30.3738317757009, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321647, Length=206, Percent_Identity=42.7184466019417, Blast_Score=152, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24661601, Length=191, Percent_Identity=28.2722513089005, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 33523; Mature: 33523

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTSEYVLQNRLHALATSGQCQLSLYEEGQAPQGERVRLVWATKATEELIFARLAELNC
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHCCC
AAAPLVRRNALSGLELVSKGEGNLSAAFDGIAGLEVLPVTESLPSLRHPGLLVMDMDSTA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEECCHHCCCCCCCCEEEEECCCCE
IKIECIDELAAMAGVGEAVAEVTERAMQGELDFKQSLRQRVAKLAGADAGIIDTLCARLP
EEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
LMDGLTEMLAELKGHGWKLVVASGGFTPFVGHLKATLGLDAAFANELVIADGKLVGEVTG
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHCCEEEECCEEEEEEEC
TVVDANFKADVVSRLGDEYGIKDGQRLAIGDGANDIPMVQRADFGIAFHAKPKLAAAADA
EEEECCCHHHHHHHCCHHCCCCCCCEEEECCCCCCCCCEEECCCCEEEECCCCHHHHCCC
RIHTLDLRVLPFLLQA
EEEEEHHHHHHHHHCC
>Mature Secondary Structure
MENTSEYVLQNRLHALATSGQCQLSLYEEGQAPQGERVRLVWATKATEELIFARLAELNC
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHCCC
AAAPLVRRNALSGLELVSKGEGNLSAAFDGIAGLEVLPVTESLPSLRHPGLLVMDMDSTA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEECCHHCCCCCCCCEEEEECCCCE
IKIECIDELAAMAGVGEAVAEVTERAMQGELDFKQSLRQRVAKLAGADAGIIDTLCARLP
EEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
LMDGLTEMLAELKGHGWKLVVASGGFTPFVGHLKATLGLDAAFANELVIADGKLVGEVTG
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHCCEEEECCEEEEEEEC
TVVDANFKADVVSRLGDEYGIKDGQRLAIGDGANDIPMVQRADFGIAFHAKPKLAAAADA
EEEECCCHHHHHHHCCHHCCCCCCCEEEECCCCCCCCCEEECCCCEEEECCCCHHHHCCC
RIHTLDLRVLPFLLQA
EEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]