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The map label for this gene is deoD [H]

Identifier: 119774113

GI number: 119774113

Start: 1180325

End: 1181035

Strand: Direct

Name: deoD [H]

Synonym: Sama_0976

Alternate gene names: 119774113

Gene position: 1180325-1181035 (Clockwise)

Preceding gene: 119774112

Following gene: 119774115

Centisome position: 27.41

GC content: 53.87

Gene sequence:

>711_bases
ATGGCTACACCACACATTAATGCTGTAGAAGGTGCATTTGCTGAAACCGTACTTTTCCCGGGCGATCCGCTGCGTGCCAA
GTACATTGCCGAAACCTTCCTCGAAAACGTTGAGCAGGTTACCGATGTACGTAACATGTTGGGCTTCACCGGTACTTACA
AGGGCAAGCGCATCTCTGTGATGGGCTCTGGCATGGGTATCCCAAGCTGTTCTATTTACGCTACCGAGCTTATCAAAGAC
TATGGCGTGAAGAACCTCATCCGTGTGGGTACCTGTGGTGCCATCAGCACTGACGTTAAGGTTCGTGACGTGATCATCGG
TATGGGCGCCTGTACTGATTCTCAGGTAAACCGTCTGCGCTTCAAGGGCCAGGACTTTGCCGCCATCGCCGACTACAGCC
TGCTGAGCGCCGTGGTTGAGTCTGCCAAGACTCACGGTATCCAGACCCGCGTTGGTAACGTATTCTCTGCCGACCTGTTC
TACACGCCAGATCCTGAAATGTTCGACGTGATGGAGAAGATGGGTGTTCTGGGCGTTGAGATGGAAGCCGCCGGTCTGTA
CGGTGTGGCTCACGAGTTCGGTGCCCGCGCGCTGTGTGTGGTAACTGTATCTGATCACATCCGTACCGGTGAGAAGACTA
CCTCTGATGAGCGTCAGACCACCTTCAACGACATGATCATCATGACCCTGGATGCGGCCATCAACCTCTGA

Upstream 100 bases:

>100_bases
CCCGCTAAGGTCTGCTGAAAAAGTTTCGTTTTGGCGACTTCCTTTGAGTCGCCTATTATCAAAGACTTAAGTCTTAATCA
AAAATACAGGGGTTATACAG

Downstream 100 bases:

>100_bases
TGCTGGATCTGTGACAGGCTAAAGCCTGTCAGGTACGAAAAAGGCTCCCTCGGGAGCTTTTTTGTTTACATGCTTTTGCT
TCAGCCTGCATTGCAGCATC

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP 2 [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISVMGSGMGIPSCSIYATELIKD
YGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLRFKGQDFAAIADYSLLSAVVESAKTHGIQTRVGNVFSADLF
YTPDPEMFDVMEKMGVLGVEMEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTTSDERQTTFNDMIIMTLDAAINL

Sequences:

>Translated_236_residues
MATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISVMGSGMGIPSCSIYATELIKD
YGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLRFKGQDFAAIADYSLLSAVVESAKTHGIQTRVGNVFSADLF
YTPDPEMFDVMEKMGVLGVEMEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTTSDERQTTFNDMIIMTLDAAINL
>Mature_235_residues
ATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISVMGSGMGIPSCSIYATELIKDY
GVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLRFKGQDFAAIADYSLLSAVVESAKTHGIQTRVGNVFSADLFY
TPDPEMFDVMEKMGVLGVEMEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTTSDERQTTFNDMIIMTLDAAINL

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=234, Percent_Identity=70.9401709401709, Blast_Score=352, Evalue=1e-98,
Organism=Escherichia coli, GI1790265, Length=238, Percent_Identity=29.4117647058824, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25528; Mature: 25396

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISV
CCCCCCCHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MGSGMGIPSCSIYATELIKDYGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLR
EECCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHE
FKGQDFAAIADYSLLSAVVESAKTHGIQTRVGNVFSADLFYTPDPEMFDVMEKMGVLGVE
ECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECEEECCCCHHHHHHHHCCCEEEE
MEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTTSDERQTTFNDMIIMTLDAAINL
EHHCHHHHHHHHHCCCEEEEEEECCHHCCCCCCCCCHHHHHHHCEEEEEECCHHCC
>Mature Secondary Structure 
ATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISV
CCCCCCHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MGSGMGIPSCSIYATELIKDYGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLR
EECCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHE
FKGQDFAAIADYSLLSAVVESAKTHGIQTRVGNVFSADLFYTPDPEMFDVMEKMGVLGVE
ECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECEEECCCCHHHHHHHHCCCEEEE
MEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTTSDERQTTFNDMIIMTLDAAINL
EHHCHHHHHHHHHCCCEEEEEEECCHHCCCCCCCCCHHHHHHHCEEEEEECCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]