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The map label for this gene is aer [H]

Identifier: 119773672

GI number: 119773672

Start: 655435

End: 657006

Strand: Direct

Name: aer [H]

Synonym: Sama_0532

Alternate gene names: 119773672

Gene position: 655435-657006 (Clockwise)

Preceding gene: 119773671

Following gene: 119773673

Centisome position: 15.22

GC content: 56.81

Gene sequence:

>1572_bases
ATGCGCAACAACCAACCCGTCACCCTCAGGGAAGTGGAGCTCGACAACGAGGCCATCATTCTGTCAACCACGGATCTGAA
AGGGCGTATCAAGTACGTCAATCAGGACTTCTGCAATATTGCCGGTTTCCGGGAAGAGGAACTGGTGCATGAGCCGCACA
ATCTCATCCGCCACCCCGATATGCCACCCGCTGCATTCAAGATGCTCTGGAGTCGCATTCGCGAAGGGCGCCCCTGGATG
GGGTTGGTGAAAAACCGCTGCAAGAACGGGGACTATTACTGGGTCGATGCGTATGTCACCCCCGTGTATGAAGATGGCGA
AGTCCACGAATACCAGTCGGTGCGCCGCAAGGTGAACGCCAAGCACCGGGAGCGCGCCGAGTCCTTGTATGCCGAGTTGG
TGAAAGATCCTCAGCCCGCAATACTCAGAGATAGTCGCTTTGGTGTGTGTGGCAAACTCATGCTGTGGATGGCCCTGATG
CTGGGAGTATCGGCCGTTGCCGCACAGTGGTCTCTTTGGTTGGTGTTACTGCTGTTGCCCATTGCCCTCTTGGGTTGCCG
TAGCTTATTGGCGCCGCTTCGAGAGCTTGCCAGTGAGGCTCGCAGTATTATTCAGGACCCCGTGGCCAGAGCGGTTTATA
CAGGTCGGCGGGATGAAATTGGTGACCTCATGCTGGCCATGCGCTTTATGACCAATGAAACCGGCGGTGTGATGGGGCGG
ATGGCAGATTCCACCGAGACCATGGCGAACCAAAGCAATGATCTGCTTGATGCCATCGCCCGCAGCGCCGAACGGGCCGA
CGGTCAGCGTCAGCAAACCCAGCAGGCCGCCGCTGCGGTGGAAGAACTGCACGTGAGTTTTGCCGAAGTCAAAGAACATA
CACTGGCCGTGGTCAGCGATGTGGAACAATGCCAAAGTGCCATGGGGCTTGGGCAACAGCAGCTGGCGGAGGTCGAACTG
GCCATGCAGCAGCTACAGCACCAAATGAGTCTGTGCGATGCCGTTGTGCGTGAGATTGCCAGCGACAGCCAGGCCATCAA
TCAGGTGCTTGAAGTCATTGGCACCATAGCTGAGCAAACCAATCTGCTCGCCCTCAATGCGGCAATCGAGGCGGCCCGTG
CCGGTGAGTCCGGACGTGGTTTTGCCGTGGTGGCCGATGAAGTGCGGCAGCTTTCAGGACGTACCGGTGAGTCAACCGGA
CAGATAGAAGGCATAGTGCGTAAATTCCAGTCCAGTACGGCGAGGGCCGAAGCCAATCTGGACAACAGTCAGCAGCAGCT
TAAGACATTGGCAGCAAGACTTGGACAGGTTCAGCAGGCCTTTGGCGCGCTGGAAGGCGCCATCAATACCATCAAATCTC
TTTCCGACCACAGTGCCCATGCCATGACAGAGCAGTCCAGTGCCGCAGGCAGTATCAGTGACTCGCTGCAAACCATCAAT
GAACTTGCAGAAGCCGTGCTCAACCAATCCCGGGAGGCCGAGCAGTTGGGTGCCCGTATGTCACGCCTTTCAAGTAAAAC
CAGTGGCTTATCCAAGCAGTTTTGGCAAAAAAGTGTGAGCGGCCGAGACTAG

Upstream 100 bases:

>100_bases
AAACCATTACCTGATTGCGACTTTCTTTGCACTGCATCAATTTAATACAGGCGTTAAACGGTCAAAATCTTGCGCATCAA
TTGGCCAACAAGAATAAAAG

Downstream 100 bases:

>100_bases
GCGGCACGCATTTTCGGCCAAGAGTTGATATGAAGAGGTCCGCTATCGCGGGCCTTTTTATCTTTTTGTCGCTCACAAGA
CTTAACACCTGTGTAAGGCG

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MRNNQPVTLREVELDNEAIILSTTDLKGRIKYVNQDFCNIAGFREEELVHEPHNLIRHPDMPPAAFKMLWSRIREGRPWM
GLVKNRCKNGDYYWVDAYVTPVYEDGEVHEYQSVRRKVNAKHRERAESLYAELVKDPQPAILRDSRFGVCGKLMLWMALM
LGVSAVAAQWSLWLVLLLLPIALLGCRSLLAPLRELASEARSIIQDPVARAVYTGRRDEIGDLMLAMRFMTNETGGVMGR
MADSTETMANQSNDLLDAIARSAERADGQRQQTQQAAAAVEELHVSFAEVKEHTLAVVSDVEQCQSAMGLGQQQLAEVEL
AMQQLQHQMSLCDAVVREIASDSQAINQVLEVIGTIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSGRTGESTG
QIEGIVRKFQSSTARAEANLDNSQQQLKTLAARLGQVQQAFGALEGAINTIKSLSDHSAHAMTEQSSAAGSISDSLQTIN
ELAEAVLNQSREAEQLGARMSRLSSKTSGLSKQFWQKSVSGRD

Sequences:

>Translated_523_residues
MRNNQPVTLREVELDNEAIILSTTDLKGRIKYVNQDFCNIAGFREEELVHEPHNLIRHPDMPPAAFKMLWSRIREGRPWM
GLVKNRCKNGDYYWVDAYVTPVYEDGEVHEYQSVRRKVNAKHRERAESLYAELVKDPQPAILRDSRFGVCGKLMLWMALM
LGVSAVAAQWSLWLVLLLLPIALLGCRSLLAPLRELASEARSIIQDPVARAVYTGRRDEIGDLMLAMRFMTNETGGVMGR
MADSTETMANQSNDLLDAIARSAERADGQRQQTQQAAAAVEELHVSFAEVKEHTLAVVSDVEQCQSAMGLGQQQLAEVEL
AMQQLQHQMSLCDAVVREIASDSQAINQVLEVIGTIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSGRTGESTG
QIEGIVRKFQSSTARAEANLDNSQQQLKTLAARLGQVQQAFGALEGAINTIKSLSDHSAHAMTEQSSAAGSISDSLQTIN
ELAEAVLNQSREAEQLGARMSRLSSKTSGLSKQFWQKSVSGRD
>Mature_523_residues
MRNNQPVTLREVELDNEAIILSTTDLKGRIKYVNQDFCNIAGFREEELVHEPHNLIRHPDMPPAAFKMLWSRIREGRPWM
GLVKNRCKNGDYYWVDAYVTPVYEDGEVHEYQSVRRKVNAKHRERAESLYAELVKDPQPAILRDSRFGVCGKLMLWMALM
LGVSAVAAQWSLWLVLLLLPIALLGCRSLLAPLRELASEARSIIQDPVARAVYTGRRDEIGDLMLAMRFMTNETGGVMGR
MADSTETMANQSNDLLDAIARSAERADGQRQQTQQAAAAVEELHVSFAEVKEHTLAVVSDVEQCQSAMGLGQQQLAEVEL
AMQQLQHQMSLCDAVVREIASDSQAINQVLEVIGTIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSGRTGESTG
QIEGIVRKFQSSTARAEANLDNSQQQLKTLAARLGQVQQAFGALEGAINTIKSLSDHSAHAMTEQSSAAGSISDSLQTIN
ELAEAVLNQSREAEQLGARMSRLSSKTSGLSKQFWQKSVSGRD

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=537, Percent_Identity=27.56052141527, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1788195, Length=226, Percent_Identity=35.3982300884956, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI2367378, Length=256, Percent_Identity=31.25, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787690, Length=332, Percent_Identity=27.1084337349398, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788194, Length=251, Percent_Identity=28.2868525896414, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57615; Mature: 57615

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNQPVTLREVELDNEAIILSTTDLKGRIKYVNQDFCNIAGFREEELVHEPHNLIRHPD
CCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHCCCC
MPPAAFKMLWSRIREGRPWMGLVKNRCKNGDYYWVDAYVTPVYEDGEVHEYQSVRRKVNA
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCH
KHRERAESLYAELVKDPQPAILRDSRFGVCGKLMLWMALMLGVSAVAAQWSLWLVLLLLP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALLGCRSLLAPLRELASEARSIIQDPVARAVYTGRRDEIGDLMLAMRFMTNETGGVMGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHH
MADSTETMANQSNDLLDAIARSAERADGQRQQTQQAAAAVEELHVSFAEVKEHTLAVVSD
HCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEQCQSAMGLGQQQLAEVELAMQQLQHQMSLCDAVVREIASDSQAINQVLEVIGTIAEQT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
NLLALNAAIEAARAGESGRGFAVVADEVRQLSGRTGESTGQIEGIVRKFQSSTARAEANL
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
DNSQQQLKTLAARLGQVQQAFGALEGAINTIKSLSDHSAHAMTEQSSAAGSISDSLQTIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHH
ELAEAVLNQSREAEQLGARMSRLSSKTSGLSKQFWQKSVSGRD
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRNNQPVTLREVELDNEAIILSTTDLKGRIKYVNQDFCNIAGFREEELVHEPHNLIRHPD
CCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHCCCC
MPPAAFKMLWSRIREGRPWMGLVKNRCKNGDYYWVDAYVTPVYEDGEVHEYQSVRRKVNA
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCH
KHRERAESLYAELVKDPQPAILRDSRFGVCGKLMLWMALMLGVSAVAAQWSLWLVLLLLP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALLGCRSLLAPLRELASEARSIIQDPVARAVYTGRRDEIGDLMLAMRFMTNETGGVMGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHH
MADSTETMANQSNDLLDAIARSAERADGQRQQTQQAAAAVEELHVSFAEVKEHTLAVVSD
HCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEQCQSAMGLGQQQLAEVELAMQQLQHQMSLCDAVVREIASDSQAINQVLEVIGTIAEQT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
NLLALNAAIEAARAGESGRGFAVVADEVRQLSGRTGESTGQIEGIVRKFQSSTARAEANL
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
DNSQQQLKTLAARLGQVQQAFGALEGAINTIKSLSDHSAHAMTEQSSAAGSISDSLQTIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHH
ELAEAVLNQSREAEQLGARMSRLSSKTSGLSKQFWQKSVSGRD
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]