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The map label for this gene is qorA [H]

Identifier: 119773673

GI number: 119773673

Start: 657261

End: 658262

Strand: Direct

Name: qorA [H]

Synonym: Sama_0533

Alternate gene names: 119773673

Gene position: 657261-658262 (Clockwise)

Preceding gene: 119773672

Following gene: 119773674

Centisome position: 15.26

GC content: 59.28

Gene sequence:

>1002_bases
ATGACTTCATTCCACACTCAGGTTGTGTTTGATGCCCCCGGTAGCCCCGAGGTTATGAAACTGGTGCAAGGGCCAGCGCC
TTCCCCCCAAGTTGGAGAGGTGTTGATTAGGGTAGCCGCCGCCGGCGTTAACGGGCCGGATTTGGCGCAGCGCAAAGGTG
CTTATCCACCGCCGCCGGGCGCTTCACCAATTTTGGGCTTGGAAGTGTCCGGCGAGGTGGTTGAGGTTGCCCCCGATGTC
AGCTGGCCAAGGATAGGTGACAAGGTCTGCGCCCTGGTGCCCGGCGGTGGTTATGCCGGCTTGGTGGTGACCCCTGCGCT
GCACTGTTTGCCCATACCGTTAACTATGTCCCTCGAAGAGGCCGCGGGCCTGCCTGAAACCTTCTTTACCGTGTGGGGCA
ATCTCTTTATGCGCGCTGGCCTCAAGGCGGGCGAGACCCTGCTTATCCAGGGTGGCAGCGGTGGCATAGGCTCCACGGCG
ATTCTGCTGGCCAGGGCGTTTGGCGCGCGGGTACTGGTGACCTCCGGCAGTGCAGAAAAACGGGAATATTGCGTGAGTCT
GGGGGCTGACATGGCCTTTGACTATCGGGATGAGGCGCTGGTTGACCGGGTGCTTGCGGCCACAGACGGCCGGGGTGTGG
ATGTCGTGCTGGACATGGCAGGTGGTGCCATGGTCAATAACAATCTGAAAATGCTCGCCAATGATGGCCGTATGGTCTCC
GTGGCCATGCAGGCAGGTCCCAGGGCCGAGGTGGATGTGTTTCGCATCATGAGTAAACGCATCCTGTGGACGGGCTCCAC
TTTAAGACCCCAGAGTATCGAGGCCAAAGCGGCCATCGCCAAAGAACTGAGGGAGAAGGTTTGGCCGCTGCTCGACAGCG
GCCAATGCCGTATACCTCTTTTTGGCGTGTATCGGCTCGATGAAGTGGTTAAAGTCCACAGCATCATGGAGGCAAAATCC
CACCACGGAAAGCTGGTGCTCAGTCTCGATGGAATTGCTTGA

Upstream 100 bases:

>100_bases
GCGGCTGTATGTTTCAAGTCCCGGTTAAGTTTCGTCTTTTAGCTTTGTCGGAAGCTGCTATGCTTGGGACAACTTTTCTC
AGTCTGCGTAATTTTCCTTT

Downstream 100 bases:

>100_bases
TATGGCGAAATTTTCGACTAAAGTCGAGATTAAACGGAAAAATGAAAAAAACAGGTTGAAATTAATCTAAATATCACAAA
AAAATCGCTTAATTTGGCAT

Product: alcohol dehydrogenase, zinc-containing

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTSFHTQVVFDAPGSPEVMKLVQGPAPSPQVGEVLIRVAAAGVNGPDLAQRKGAYPPPPGASPILGLEVSGEVVEVAPDV
SWPRIGDKVCALVPGGGYAGLVVTPALHCLPIPLTMSLEEAAGLPETFFTVWGNLFMRAGLKAGETLLIQGGSGGIGSTA
ILLARAFGARVLVTSGSAEKREYCVSLGADMAFDYRDEALVDRVLAATDGRGVDVVLDMAGGAMVNNNLKMLANDGRMVS
VAMQAGPRAEVDVFRIMSKRILWTGSTLRPQSIEAKAAIAKELREKVWPLLDSGQCRIPLFGVYRLDEVVKVHSIMEAKS
HHGKLVLSLDGIA

Sequences:

>Translated_333_residues
MTSFHTQVVFDAPGSPEVMKLVQGPAPSPQVGEVLIRVAAAGVNGPDLAQRKGAYPPPPGASPILGLEVSGEVVEVAPDV
SWPRIGDKVCALVPGGGYAGLVVTPALHCLPIPLTMSLEEAAGLPETFFTVWGNLFMRAGLKAGETLLIQGGSGGIGSTA
ILLARAFGARVLVTSGSAEKREYCVSLGADMAFDYRDEALVDRVLAATDGRGVDVVLDMAGGAMVNNNLKMLANDGRMVS
VAMQAGPRAEVDVFRIMSKRILWTGSTLRPQSIEAKAAIAKELREKVWPLLDSGQCRIPLFGVYRLDEVVKVHSIMEAKS
HHGKLVLSLDGIA
>Mature_332_residues
TSFHTQVVFDAPGSPEVMKLVQGPAPSPQVGEVLIRVAAAGVNGPDLAQRKGAYPPPPGASPILGLEVSGEVVEVAPDVS
WPRIGDKVCALVPGGGYAGLVVTPALHCLPIPLTMSLEEAAGLPETFFTVWGNLFMRAGLKAGETLLIQGGSGGIGSTAI
LLARAFGARVLVTSGSAEKREYCVSLGADMAFDYRDEALVDRVLAATDGRGVDVVLDMAGGAMVNNNLKMLANDGRMVSV
AMQAGPRAEVDVFRIMSKRILWTGSTLRPQSIEAKAAIAKELREKVWPLLDSGQCRIPLFGVYRLDEVVKVHSIMEAKSH
HGKLVLSLDGIA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=38.719512195122, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=38.719512195122, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI194239674, Length=319, Percent_Identity=28.2131661442006, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI13236495, Length=319, Percent_Identity=28.2131661442006, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI24308257, Length=344, Percent_Identity=27.3255813953488, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI41872631, Length=220, Percent_Identity=34.5454545454545, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI194239676, Length=193, Percent_Identity=32.6424870466321, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=25.4019292604502, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI28557745, Length=223, Percent_Identity=31.8385650224215, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI197927207, Length=199, Percent_Identity=27.1356783919598, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI47519420, Length=244, Percent_Identity=29.5081967213115, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1790485, Length=328, Percent_Identity=29.8780487804878, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17507255, Length=328, Percent_Identity=28.0487804878049, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI212642053, Length=217, Percent_Identity=29.9539170506912, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536829, Length=296, Percent_Identity=26.0135135135135, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=329, Percent_Identity=26.7477203647416, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=307, Percent_Identity=28.0130293159609, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=290, Percent_Identity=28.2758620689655, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=344, Percent_Identity=26.453488372093, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=332, Percent_Identity=25, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221330659, Length=182, Percent_Identity=33.5164835164835, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920632, Length=182, Percent_Identity=33.5164835164835, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24581345, Length=182, Percent_Identity=30.2197802197802, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35045; Mature: 34914

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFHTQVVFDAPGSPEVMKLVQGPAPSPQVGEVLIRVAAAGVNGPDLAQRKGAYPPPPG
CCCCEEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
ASPILGLEVSGEVVEVAPDVSWPRIGDKVCALVPGGGYAGLVVTPALHCLPIPLTMSLEE
CCCEEEEEECCCEEEECCCCCCCCCCCEEEEEECCCCEECHHHHCCHHHCCCCEEEEHHH
AAGLPETFFTVWGNLFMRAGLKAGETLLIQGGSGGIGSTAILLARAFGARVLVTSGSAEK
HCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEECCCCHH
REYCVSLGADMAFDYRDEALVDRVLAATDGRGVDVVLDMAGGAMVNNNLKMLANDGRMVS
HHHHHHCCCCCEECCCHHHHHHHHHHHCCCCCEEEEEEECCCEEECCCEEEEECCCEEEE
VAMQAGPRAEVDVFRIMSKRILWTGSTLRPQSIEAKAAIAKELREKVWPLLDSGQCRIPL
EEECCCCCCHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEE
FGVYRLDEVVKVHSIMEAKSHHGKLVLSLDGIA
EEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
>Mature Secondary Structure 
TSFHTQVVFDAPGSPEVMKLVQGPAPSPQVGEVLIRVAAAGVNGPDLAQRKGAYPPPPG
CCCEEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
ASPILGLEVSGEVVEVAPDVSWPRIGDKVCALVPGGGYAGLVVTPALHCLPIPLTMSLEE
CCCEEEEEECCCEEEECCCCCCCCCCCEEEEEECCCCEECHHHHCCHHHCCCCEEEEHHH
AAGLPETFFTVWGNLFMRAGLKAGETLLIQGGSGGIGSTAILLARAFGARVLVTSGSAEK
HCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEECCCCHH
REYCVSLGADMAFDYRDEALVDRVLAATDGRGVDVVLDMAGGAMVNNNLKMLANDGRMVS
HHHHHHCCCCCEECCCHHHHHHHHHHHCCCCCEEEEEEECCCEEECCCEEEEECCCEEEE
VAMQAGPRAEVDVFRIMSKRILWTGSTLRPQSIEAKAAIAKELREKVWPLLDSGQCRIPL
EEECCCCCCHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEE
FGVYRLDEVVKVHSIMEAKSHHGKLVLSLDGIA
EEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]