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The map label for this gene is argE [H]

Identifier: 119773396

GI number: 119773396

Start: 292656

End: 293807

Strand: Reverse

Name: argE [H]

Synonym: Sama_0255

Alternate gene names: 119773396

Gene position: 293807-292656 (Counterclockwise)

Preceding gene: 119773402

Following gene: 119773395

Centisome position: 6.82

GC content: 52.34

Gene sequence:

>1152_bases
GTGAAAGTCATTCCAGATCTCAAGAGTCGTTTCTCCTCGCTCATTTATGCACCATCAATCAGTGCAACCGAACCACAACT
GGATATGAGTAATCATTCAGTTATCGCCCTGCTGAACGACTGGTTTTCGGATCTGGGATTTGACTGTCAAGTAACAAAGG
TAGCAGGCACCCGCGACAAACGGAATTTGCTGGCTAAAATCGGTAGCGGTGAAGGTGGCCTGCTATTGGCAGGACACACT
GACACCGTGCCTTTTGACGAAGGCCGCTGGAGCCAGGATCCCTTTGTACTGACCGAAAAGGACGACCGTTGGTACGGCCT
TGGCAGTTGCGACATGAAAGGTTTTTTTGCGCTGATCCTTGAAGCGGCGAAAGATTTACCCCTGCATAACCTGCAAAAGC
CGCTTTATATCTTTGCCAGCGCCGATGAAGAAACGACTATGGAAGGCGCCAAAGCGTTTGCGGCCAATACCGGCATTCGC
CCCGAGTACGCCATCATTGGCGAACCCACAGGCCTTAAACCCGTGTATATGCACAAAGGCCATCTGGCTCAGGGGATACG
CATTACGGGCCGCAGCGGCCATTCATCCGATCCCGCCCGTGGTCTCAATGCCATCGAAATCATGCACAAGGTCATTGGGC
AGTTGCTGAAGCTCAAACAACACCTGGCCGACAATTACCGTGAAGACGCCTTCAGCGTGCCGTACCCCACCATGAACTTT
GGCCATATTCACGGCGGCGATGCCGCCAACCGAATTTGCGGCTGTTGTGATTTGCATTTGGACATTCGCCCGCTGCCGGG
ATTGGCGCTGGAGGATTTAGAGCTGATGCTTGTCAACTATCTGCAGGACATTACTCGCGACTATCCCGGTTCAGTTGACA
TCCGCACCCTCTATCCGGGCAGCGAAGCCTTTGCCGGGGTAAAAGACAGTGCCTGGACCCAACTGGTGGAAAGTCTCTCA
GGTCAACAGGCTGAAGTGGTGAACTACGCCACCGAAGCCCCTTACATCAATAAACTGGGCTGCCAAACCCTGGTTTTGGG
GCCGGGAAGCATCAACCAGGCCCATCAGCCAGATGAATATATGGCAATGGACCAGTTAAAACCCACGGTAGAATTATTGA
AACAGTTGATCCATAAGGCCTGTATTCAATAA

Upstream 100 bases:

>100_bases
TCGAGGCCCTGGCTATGGTGCTGGTCCCGGCTGTTTGCTAGACTAACACAACTCTTTAATTATGCAATATGCATGAATAT
CTATTTCAGGAAAATTTACA

Downstream 100 bases:

>100_bases
ACCATAAACCGACATCGAAAATACCACAATTGGACTGACCAATTGACCCTGGTCGGTTGACCCCGAACGCAGGGCTGTTT
ATTGTGCTTGAACGGCTTTG

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKVIPDLKSRFSSLIYAPSISATEPQLDMSNHSVIALLNDWFSDLGFDCQVTKVAGTRDKRNLLAKIGSGEGGLLLAGHT
DTVPFDEGRWSQDPFVLTEKDDRWYGLGSCDMKGFFALILEAAKDLPLHNLQKPLYIFASADEETTMEGAKAFAANTGIR
PEYAIIGEPTGLKPVYMHKGHLAQGIRITGRSGHSSDPARGLNAIEIMHKVIGQLLKLKQHLADNYREDAFSVPYPTMNF
GHIHGGDAANRICGCCDLHLDIRPLPGLALEDLELMLVNYLQDITRDYPGSVDIRTLYPGSEAFAGVKDSAWTQLVESLS
GQQAEVVNYATEAPYINKLGCQTLVLGPGSINQAHQPDEYMAMDQLKPTVELLKQLIHKACIQ

Sequences:

>Translated_383_residues
MKVIPDLKSRFSSLIYAPSISATEPQLDMSNHSVIALLNDWFSDLGFDCQVTKVAGTRDKRNLLAKIGSGEGGLLLAGHT
DTVPFDEGRWSQDPFVLTEKDDRWYGLGSCDMKGFFALILEAAKDLPLHNLQKPLYIFASADEETTMEGAKAFAANTGIR
PEYAIIGEPTGLKPVYMHKGHLAQGIRITGRSGHSSDPARGLNAIEIMHKVIGQLLKLKQHLADNYREDAFSVPYPTMNF
GHIHGGDAANRICGCCDLHLDIRPLPGLALEDLELMLVNYLQDITRDYPGSVDIRTLYPGSEAFAGVKDSAWTQLVESLS
GQQAEVVNYATEAPYINKLGCQTLVLGPGSINQAHQPDEYMAMDQLKPTVELLKQLIHKACIQ
>Mature_383_residues
MKVIPDLKSRFSSLIYAPSISATEPQLDMSNHSVIALLNDWFSDLGFDCQVTKVAGTRDKRNLLAKIGSGEGGLLLAGHT
DTVPFDEGRWSQDPFVLTEKDDRWYGLGSCDMKGFFALILEAAKDLPLHNLQKPLYIFASADEETTMEGAKAFAANTGIR
PEYAIIGEPTGLKPVYMHKGHLAQGIRITGRSGHSSDPARGLNAIEIMHKVIGQLLKLKQHLADNYREDAFSVPYPTMNF
GHIHGGDAANRICGCCDLHLDIRPLPGLALEDLELMLVNYLQDITRDYPGSVDIRTLYPGSEAFAGVKDSAWTQLVESLS
GQQAEVVNYATEAPYINKLGCQTLVLGPGSINQAHQPDEYMAMDQLKPTVELLKQLIHKACIQ

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=378, Percent_Identity=57.6719576719577, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI1788816, Length=242, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789236, Length=379, Percent_Identity=25.065963060686, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17551016, Length=319, Percent_Identity=28.8401253918495, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42065; Mature: 42065

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIPDLKSRFSSLIYAPSISATEPQLDMSNHSVIALLNDWFSDLGFDCQVTKVAGTRDK
CCCCCHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCEEEEEECCCCHH
RNLLAKIGSGEGGLLLAGHTDTVPFDEGRWSQDPFVLTEKDDRWYGLGSCDMKGFFALIL
HHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHH
EAAKDLPLHNLQKPLYIFASADEETTMEGAKAFAANTGIRPEYAIIGEPTGLKPVYMHKG
HHHHCCCHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECC
HLAQGIRITGRSGHSSDPARGLNAIEIMHKVIGQLLKLKQHLADNYREDAFSVPYPTMNF
CCCCCEEEECCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GHIHGGDAANRICGCCDLHLDIRPLPGLALEDLELMLVNYLQDITRDYPGSVDIRTLYPG
CCCCCCCHHHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SEAFAGVKDSAWTQLVESLSGQQAEVVNYATEAPYINKLGCQTLVLGPGSINQAHQPDEY
CHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCCCCCHHH
MAMDQLKPTVELLKQLIHKACIQ
HHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVIPDLKSRFSSLIYAPSISATEPQLDMSNHSVIALLNDWFSDLGFDCQVTKVAGTRDK
CCCCCHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCEEEEEECCCCHH
RNLLAKIGSGEGGLLLAGHTDTVPFDEGRWSQDPFVLTEKDDRWYGLGSCDMKGFFALIL
HHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHH
EAAKDLPLHNLQKPLYIFASADEETTMEGAKAFAANTGIRPEYAIIGEPTGLKPVYMHKG
HHHHCCCHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECC
HLAQGIRITGRSGHSSDPARGLNAIEIMHKVIGQLLKLKQHLADNYREDAFSVPYPTMNF
CCCCCEEEECCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GHIHGGDAANRICGCCDLHLDIRPLPGLALEDLELMLVNYLQDITRDYPGSVDIRTLYPG
CCCCCCCHHHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SEAFAGVKDSAWTQLVESLSGQQAEVVNYATEAPYINKLGCQTLVLGPGSINQAHQPDEY
CHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCCCCCHHH
MAMDQLKPTVELLKQLIHKACIQ
HHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA