Click here to switch to the map view.

The map label for this gene is ydiD [C]

Identifier: 119773402

GI number: 119773402

Start: 299560

End: 301215

Strand: Reverse

Name: ydiD [C]

Synonym: Sama_0261

Alternate gene names: 119773402

Gene position: 301215-299560 (Counterclockwise)

Preceding gene: 119773403

Following gene: 119773396

Centisome position: 7.0

GC content: 56.4

Gene sequence:

>1656_bases
ATGCAAGCCACTATCAAGACTCCTGTAGAGATGCTCGACCATTGGGTACAAAACCAGGGTGACAAGGTTTACTTGCGCCA
GCCGGTAAACGGCCAATACCGTGATTTCAGCTGGCGGGATGTGAAACGCCAGATGGAGCAAATTGCCGGCTCGCTCAGGC
ATCTTGGTCTTGTGCCCGGAGACAAGGTCGCCGTGCTGTCCAAGAACTGCGCCGAGTGGTTTATTACCGACCTGGCGTTA
ATGCACGGCGGTTATATCAGCGTACCCATTTATCCTACCGCCAATGCCGATACCATCCGCTACGTGCTGGAGCACAGTGG
TGCCAAGGCCATTTTTATCGGCAAGCTGGACCACTGGGCCGAGCAGGAAGCCGGTGTTGGCGGCAGTATTTTGCGCATGT
CCTTCCCCTACGACACCATGCCGACCCAATACGGCTGGGACCAGTTGATGACCATGGGACAACCGCTGACAGACGCACCG
CTGCCTGCCATGGAAGATACCATGACGCTGATTTACACCTCGGGCTCCACTGGCAGCCCGAAGGGTGCAATTCAAACCTT
TGGCAGCTATTGCTGGACCTGTACTGCCGTGGTGCGCGATCTCAAAACCGACGGTGACGATAGATTGCTGTCGTACCTGC
CACTGGCCCATATCACCGAGCGGGTCGCCATTGAAGGGTCATCCTTCTATTCCGGCAGCGCGGTGGCCTTTGTCGAGAGT
CTGGATACCTTCGTCGCCGACGTGCAGCGCATGCGACCAACCGTATTCTTCTCGGTGCCACGTCTTTGGACCCTGTTCCA
GAAAAACATTATCGACAAGGTGGGTTTCGACAAGCTCAACTTCCTGCTCAAGCTGCCCCTCATCAGCTATCTGGTAAAAC
GCAAAATTCACAAGGGACTTGGCCTGGATAAGTGCCGCTTGCTGGGCTCAGGTTCTGCGCCTATCCCGCCATCACTCATT
CAGTGGTACCACAGCATAGGGCTGAATATCTGCGAAGCCTGGGGCATGACCGAAAACTGTGCCTACTCCATCATCAATTA
TCCCTTTGATGCCAGCAAAATCGGTACCGTGGGAAAGCCGGTGGAAGGCTGCCTGGTGCGCCGCAGCGAAAGCGGTGAAC
TCATGGTCAAGAGTCCCGGGCTGATGAGTGGCTACTACCAGCAGCCCGAAGCCTCCGCTGCCGCCTTCGATGAAGATGGC
TTTTTCCACACCGGCGATCTCTGCGCCATCGATGAAGATGGTTGCGTCAGCATCACCGGCCGGGTGAAAGACAACTTTAA
AACCGCCAAGGGCAAGTACGTGGCCCCAGTGCCTATCGAGCGCAAGCTGGCTCAGGATCCCCATGTGGAGCTGATTTGCG
TGATTGGCTCGGGTCTGCCCCACCCCATCGCACTGGTGCAACTGTCAGACGGTGCCACCCTGCAAGCCCGGGAAGAGGTT
CGCGCTTCCATCAAGGCCACCCTGGATGCGGTGAATCCTCATCTGGAATCCCACGAAACCGTGGATGCCGTGGTGGTAGT
CAACGCCCCCTGGACCATTGAAAACGATGTGCTCACCCCAACGCTGAAAATCAAACGCCATGTGCTGGAAGCCAGATACA
GTGCCAAGGTAGATGGCGTTCGTGGTGCCAAGGTGGTGTGGGAAGACGAGATTTAA

Upstream 100 bases:

>100_bases
CCATTTGCGAGGCTGGAGAAAAATAGACATACTGGAAGTTAAACGCGCGTTTAACACCGATTTAACGCCGATAAAGATAA
CAAACAAGATGGAAGTAGCG

Downstream 100 bases:

>100_bases
TCCACTCTTTAAACGAAAAAGCTCGCCGGATGGCGAGCTTTTTTATTGCCTGCTGAGCAGGCTCAGTATTGCTGCTGTTT
GGCCGCCAGTGCAGCTGTCA

Product: AMP-dependent synthetase and ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MQATIKTPVEMLDHWVQNQGDKVYLRQPVNGQYRDFSWRDVKRQMEQIAGSLRHLGLVPGDKVAVLSKNCAEWFITDLAL
MHGGYISVPIYPTANADTIRYVLEHSGAKAIFIGKLDHWAEQEAGVGGSILRMSFPYDTMPTQYGWDQLMTMGQPLTDAP
LPAMEDTMTLIYTSGSTGSPKGAIQTFGSYCWTCTAVVRDLKTDGDDRLLSYLPLAHITERVAIEGSSFYSGSAVAFVES
LDTFVADVQRMRPTVFFSVPRLWTLFQKNIIDKVGFDKLNFLLKLPLISYLVKRKIHKGLGLDKCRLLGSGSAPIPPSLI
QWYHSIGLNICEAWGMTENCAYSIINYPFDASKIGTVGKPVEGCLVRRSESGELMVKSPGLMSGYYQQPEASAAAFDEDG
FFHTGDLCAIDEDGCVSITGRVKDNFKTAKGKYVAPVPIERKLAQDPHVELICVIGSGLPHPIALVQLSDGATLQAREEV
RASIKATLDAVNPHLESHETVDAVVVVNAPWTIENDVLTPTLKIKRHVLEARYSAKVDGVRGAKVVWEDEI

Sequences:

>Translated_551_residues
MQATIKTPVEMLDHWVQNQGDKVYLRQPVNGQYRDFSWRDVKRQMEQIAGSLRHLGLVPGDKVAVLSKNCAEWFITDLAL
MHGGYISVPIYPTANADTIRYVLEHSGAKAIFIGKLDHWAEQEAGVGGSILRMSFPYDTMPTQYGWDQLMTMGQPLTDAP
LPAMEDTMTLIYTSGSTGSPKGAIQTFGSYCWTCTAVVRDLKTDGDDRLLSYLPLAHITERVAIEGSSFYSGSAVAFVES
LDTFVADVQRMRPTVFFSVPRLWTLFQKNIIDKVGFDKLNFLLKLPLISYLVKRKIHKGLGLDKCRLLGSGSAPIPPSLI
QWYHSIGLNICEAWGMTENCAYSIINYPFDASKIGTVGKPVEGCLVRRSESGELMVKSPGLMSGYYQQPEASAAAFDEDG
FFHTGDLCAIDEDGCVSITGRVKDNFKTAKGKYVAPVPIERKLAQDPHVELICVIGSGLPHPIALVQLSDGATLQAREEV
RASIKATLDAVNPHLESHETVDAVVVVNAPWTIENDVLTPTLKIKRHVLEARYSAKVDGVRGAKVVWEDEI
>Mature_551_residues
MQATIKTPVEMLDHWVQNQGDKVYLRQPVNGQYRDFSWRDVKRQMEQIAGSLRHLGLVPGDKVAVLSKNCAEWFITDLAL
MHGGYISVPIYPTANADTIRYVLEHSGAKAIFIGKLDHWAEQEAGVGGSILRMSFPYDTMPTQYGWDQLMTMGQPLTDAP
LPAMEDTMTLIYTSGSTGSPKGAIQTFGSYCWTCTAVVRDLKTDGDDRLLSYLPLAHITERVAIEGSSFYSGSAVAFVES
LDTFVADVQRMRPTVFFSVPRLWTLFQKNIIDKVGFDKLNFLLKLPLISYLVKRKIHKGLGLDKCRLLGSGSAPIPPSLI
QWYHSIGLNICEAWGMTENCAYSIINYPFDASKIGTVGKPVEGCLVRRSESGELMVKSPGLMSGYYQQPEASAAAFDEDG
FFHTGDLCAIDEDGCVSITGRVKDNFKTAKGKYVAPVPIERKLAQDPHVELICVIGSGLPHPIALVQLSDGATLQAREEV
RASIKATLDAVNPHLESHETVDAVVVVNAPWTIENDVLTPTLKIKRHVLEARYSAKVDGVRGAKVVWEDEI

Specific function: Unknown

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI83745141, Length=572, Percent_Identity=25.8741258741259, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI42794756, Length=595, Percent_Identity=26.890756302521, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI42794760, Length=595, Percent_Identity=26.890756302521, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI42794758, Length=595, Percent_Identity=26.890756302521, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI40807491, Length=598, Percent_Identity=26.9230769230769, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI57165412, Length=598, Percent_Identity=26.2541806020067, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI57165410, Length=598, Percent_Identity=25.752508361204, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI27477105, Length=622, Percent_Identity=24.1157556270096, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI42794754, Length=632, Percent_Identity=24.8417721518987, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI42794752, Length=632, Percent_Identity=24.8417721518987, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI12669909, Length=627, Percent_Identity=23.9234449760766, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI4758332, Length=627, Percent_Identity=23.9234449760766, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI156151445, Length=547, Percent_Identity=23.400365630713, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI38524616, Length=496, Percent_Identity=22.5806451612903, Blast_Score=73, Evalue=9e-13,
Organism=Escherichia coli, GI145693145, Length=484, Percent_Identity=21.6942148760331, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788107, Length=465, Percent_Identity=24.3010752688172, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786810, Length=443, Percent_Identity=25.7336343115124, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI221142682, Length=481, Percent_Identity=25.1559251559252, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789201, Length=285, Percent_Identity=29.4736842105263, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17556552, Length=598, Percent_Identity=27.0903010033445, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17510401, Length=574, Percent_Identity=27.7003484320557, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25147511, Length=609, Percent_Identity=25.7799671592775, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17541856, Length=564, Percent_Identity=26.5957446808511, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI193204819, Length=594, Percent_Identity=24.7474747474747, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17553312, Length=604, Percent_Identity=25.9933774834437, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17564090, Length=451, Percent_Identity=26.6075388026608, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17558820, Length=300, Percent_Identity=31.3333333333333, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32563687, Length=299, Percent_Identity=33.1103678929766, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17531443, Length=503, Percent_Identity=23.0616302186879, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17557194, Length=459, Percent_Identity=25.2723311546841, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538037, Length=458, Percent_Identity=25.764192139738, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17560308, Length=482, Percent_Identity=26.1410788381743, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI133901848, Length=217, Percent_Identity=27.1889400921659, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559526, Length=429, Percent_Identity=24.9417249417249, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320852, Length=558, Percent_Identity=26.3440860215054, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324893, Length=607, Percent_Identity=23.5584843492586, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6323903, Length=454, Percent_Identity=26.8722466960352, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6322182, Length=455, Percent_Identity=25.2747252747253, Blast_Score=113, Evalue=9e-26,
Organism=Drosophila melanogaster, GI17933690, Length=617, Percent_Identity=25.2836304700162, Blast_Score=188, Evalue=8e-48,
Organism=Drosophila melanogaster, GI281366413, Length=592, Percent_Identity=23.9864864864865, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24666501, Length=592, Percent_Identity=23.9864864864865, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24666497, Length=592, Percent_Identity=23.9864864864865, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI19921316, Length=617, Percent_Identity=22.0421393841167, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI62471679, Length=584, Percent_Identity=25.3424657534247, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI62471683, Length=584, Percent_Identity=25.3424657534247, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI62471685, Length=584, Percent_Identity=25.3424657534247, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24586636, Length=584, Percent_Identity=25.3424657534247, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI62471689, Length=584, Percent_Identity=25.3424657534247, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI62471681, Length=584, Percent_Identity=25.3424657534247, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI62471687, Length=584, Percent_Identity=25.3424657534247, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24586634, Length=584, Percent_Identity=25.3424657534247, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI22026970, Length=584, Percent_Identity=25.3424657534247, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21355181, Length=473, Percent_Identity=24.7357293868922, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18859661, Length=484, Percent_Identity=22.9338842975207, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356947, Length=162, Percent_Identity=32.7160493827161, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358303, Length=177, Percent_Identity=31.638418079096, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 60803; Mature: 60803

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQATIKTPVEMLDHWVQNQGDKVYLRQPVNGQYRDFSWRDVKRQMEQIAGSLRHLGLVPG
CCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
DKVAVLSKNCAEWFITDLALMHGGYISVPIYPTANADTIRYVLEHSGAKAIFIGKLDHWA
CCEEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHHH
EQEAGVGGSILRMSFPYDTMPTQYGWDQLMTMGQPLTDAPLPAMEDTMTLIYTSGSTGSP
HHHCCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCC
KGAIQTFGSYCWTCTAVVRDLKTDGDDRLLSYLPLAHITERVAIEGSSFYSGSAVAFVES
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHEECCCCCCCCCHHHHHHH
LDTFVADVQRMRPTVFFSVPRLWTLFQKNIIDKVGFDKLNFLLKLPLISYLVKRKIHKGL
HHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
GLDKCRLLGSGSAPIPPSLIQWYHSIGLNICEAWGMTENCAYSIINYPFDASKIGTVGKP
CCCHHEEECCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCHHHEECCCCCCHHCCCCCCC
VEGCLVRRSESGELMVKSPGLMSGYYQQPEASAAAFDEDGFFHTGDLCAIDEDGCVSITG
CHHHEEEECCCCCEEEECCCCCCCCCCCCCCCHHCCCCCCCEECCCEEEECCCCCEEEEE
RVKDNFKTAKGKYVAPVPIERKLAQDPHVELICVIGSGLPHPIALVQLSDGATLQAREEV
CCCCCCCCCCCCEECCCCCHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCCHHHHHH
RASIKATLDAVNPHLESHETVDAVVVVNAPWTIENDVLTPTLKIKRHVLEARYSAKVDGV
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHCCCCCC
RGAKVVWEDEI
CCCEEEEECCC
>Mature Secondary Structure
MQATIKTPVEMLDHWVQNQGDKVYLRQPVNGQYRDFSWRDVKRQMEQIAGSLRHLGLVPG
CCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
DKVAVLSKNCAEWFITDLALMHGGYISVPIYPTANADTIRYVLEHSGAKAIFIGKLDHWA
CCEEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHHH
EQEAGVGGSILRMSFPYDTMPTQYGWDQLMTMGQPLTDAPLPAMEDTMTLIYTSGSTGSP
HHHCCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCC
KGAIQTFGSYCWTCTAVVRDLKTDGDDRLLSYLPLAHITERVAIEGSSFYSGSAVAFVES
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHEECCCCCCCCCHHHHHHH
LDTFVADVQRMRPTVFFSVPRLWTLFQKNIIDKVGFDKLNFLLKLPLISYLVKRKIHKGL
HHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
GLDKCRLLGSGSAPIPPSLIQWYHSIGLNICEAWGMTENCAYSIINYPFDASKIGTVGKP
CCCHHEEECCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCHHHEECCCCCCHHCCCCCCC
VEGCLVRRSESGELMVKSPGLMSGYYQQPEASAAAFDEDGFFHTGDLCAIDEDGCVSITG
CHHHEEEECCCCCEEEECCCCCCCCCCCCCCCHHCCCCCCCEECCCEEEECCCCCEEEEE
RVKDNFKTAKGKYVAPVPIERKLAQDPHVELICVIGSGLPHPIALVQLSDGATLQAREEV
CCCCCCCCCCCCEECCCCCHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCCHHHHHH
RASIKATLDAVNPHLESHETVDAVVVVNAPWTIENDVLTPTLKIKRHVLEARYSAKVDGV
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHCCCCCC
RGAKVVWEDEI
CCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]