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The map label for this gene is rstA [H]

Identifier: 119773296

GI number: 119773296

Start: 180034

End: 180747

Strand: Direct

Name: rstA [H]

Synonym: Sama_0154

Alternate gene names: 119773296

Gene position: 180034-180747 (Clockwise)

Preceding gene: 119773295

Following gene: 119773297

Centisome position: 4.18

GC content: 54.2

Gene sequence:

>714_bases
ATGCAAGCCAAAATCCTCTACATCGAAGATGACCATAAACTTGCCGGGTTGGTAAAGAACTTTCTGCAGTCCCATGGTTT
TGAGGTGACACACCTGCCGTCGGCCGAGGGGGCATTGGAGCAGCTCTACTACGGCAGTTTCGATTTGCTGCTCTTGGACA
TAGGCCTGCCAACGGAAGATGGCATCAGTCTGTGCCGACAAATCCGCGACCGTTTTACTGGGCAAATTCTGTTTATGACG
GCGAGGCGATCTGCCGTGGATGAGGTGGAAGGCTTGATGGCAGGCGCCGATGATTACCTCACCAAGCCGGTGGCGCCTGA
AATCCTGCTGGCGCGTATCCAAACCCGCTTAAAGCGCCGCGAGCCGCAAGAGATGGTAGAGGTTGATACTGCCAAACCCC
AATCTGAGATGCACTTTGGTCGCCTTTGCATTCGTCTTGCGGCCCGGCAGGCGTTTTGGGATGAAGAATCACTGCGTCTG
ACCACAGCCGAGTTCGATATTCTGGCGCAGCTGGCCAAACACGCAGGTCAGATAGTCTGCCGTGAAGACCTGTTCAAGTA
CACCACAGGTGCACCCTACGATGGGCTCAATCGCACCATGGACAACAGGATCAGCCGCCTCAGACGCAAGCTGGGGGATA
ACATGGACGATCCCTTTAAAATCAAAACTATCTGGGGTAAGGGTTACCTGTTTGTCCCGGATATTTGGGGCTAG

Upstream 100 bases:

>100_bases
TGCTCGGTCAGGATAACTTGCCCCTTGCCAGCGTCAGTCTCCGGGTGCTGCATATCCCTAAACGAAAACCCCGACAAAGA
GCGGCCTGGAGCCTGTTTTG

Downstream 100 bases:

>100_bases
GCATGTTGAAGCTTTACAGTGGTCTGCTATTGGCAGTCGTGAGTTCGCTACTGTTGTTCTCGCGGATTTACGATATCAGC
ACCCAGCAGCCACACCTGCT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MQAKILYIEDDHKLAGLVKNFLQSHGFEVTHLPSAEGALEQLYYGSFDLLLLDIGLPTEDGISLCRQIRDRFTGQILFMT
ARRSAVDEVEGLMAGADDYLTKPVAPEILLARIQTRLKRREPQEMVEVDTAKPQSEMHFGRLCIRLAARQAFWDEESLRL
TTAEFDILAQLAKHAGQIVCREDLFKYTTGAPYDGLNRTMDNRISRLRRKLGDNMDDPFKIKTIWGKGYLFVPDIWG

Sequences:

>Translated_237_residues
MQAKILYIEDDHKLAGLVKNFLQSHGFEVTHLPSAEGALEQLYYGSFDLLLLDIGLPTEDGISLCRQIRDRFTGQILFMT
ARRSAVDEVEGLMAGADDYLTKPVAPEILLARIQTRLKRREPQEMVEVDTAKPQSEMHFGRLCIRLAARQAFWDEESLRL
TTAEFDILAQLAKHAGQIVCREDLFKYTTGAPYDGLNRTMDNRISRLRRKLGDNMDDPFKIKTIWGKGYLFVPDIWG
>Mature_237_residues
MQAKILYIEDDHKLAGLVKNFLQSHGFEVTHLPSAEGALEQLYYGSFDLLLLDIGLPTEDGISLCRQIRDRFTGQILFMT
ARRSAVDEVEGLMAGADDYLTKPVAPEILLARIQTRLKRREPQEMVEVDTAKPQSEMHFGRLCIRLAARQAFWDEESLRL
TTAEFDILAQLAKHAGQIVCREDLFKYTTGAPYDGLNRTMDNRISRLRRKLGDNMDDPFKIKTIWGKGYLFVPDIWG

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=38.7234042553192, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=38.4615384615385, Blast_Score=163, Evalue=8e-42,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=34.3612334801762, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=38.695652173913, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=34.4827586206897, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1787229, Length=239, Percent_Identity=30.5439330543933, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=32.4675324675325, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=30.3418803418803, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=31.6239316239316, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI87082012, Length=233, Percent_Identity=32.618025751073, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=32.1888412017167, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=33.6206896551724, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=29.2576419213974, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=31.0043668122271, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27066; Mature: 27066

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAKILYIEDDHKLAGLVKNFLQSHGFEVTHLPSAEGALEQLYYGSFDLLLLDIGLPTED
CCEEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCEEEEEEECCCCCHH
GISLCRQIRDRFTGQILFMTARRSAVDEVEGLMAGADDYLTKPVAPEILLARIQTRLKRR
HHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHC
EPQEMVEVDTAKPQSEMHFGRLCIRLAARQAFWDEESLRLTTAEFDILAQLAKHAGQIVC
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCHH
REDLFKYTTGAPYDGLNRTMDNRISRLRRKLGDNMDDPFKIKTIWGKGYLFVPDIWG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEECCCCCC
>Mature Secondary Structure
MQAKILYIEDDHKLAGLVKNFLQSHGFEVTHLPSAEGALEQLYYGSFDLLLLDIGLPTED
CCEEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCEEEEEEECCCCCHH
GISLCRQIRDRFTGQILFMTARRSAVDEVEGLMAGADDYLTKPVAPEILLARIQTRLKRR
HHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHC
EPQEMVEVDTAKPQSEMHFGRLCIRLAARQAFWDEESLRLTTAEFDILAQLAKHAGQIVC
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCHH
REDLFKYTTGAPYDGLNRTMDNRISRLRRKLGDNMDDPFKIKTIWGKGYLFVPDIWG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]