Click here to switch to the map view.

The map label for this gene is fadE12 [H]

Identifier: 119718769

GI number: 119718769

Start: 4813306

End: 4814466

Strand: Reverse

Name: fadE12 [H]

Synonym: Noca_4550

Alternate gene names: 119718769

Gene position: 4814466-4813306 (Counterclockwise)

Preceding gene: 119718770

Following gene: 119718768

Centisome position: 96.56

GC content: 70.8

Gene sequence:

>1161_bases
GTGAGCAACTTCAGCGAGTCCCAGGAGCGCCAGGAGCTCCGCAAGGCCGTGGCCAAGCTGGCCGCCAAGTACGGTCGCGA
GTGGTTCACCCGGAAGGCGCGCAGCGGCGAGAAGACCACCGAGCTGTGGCTGGAGATCGGCGCCAACGGCTACCTCGGCA
TCAACATCCCCGAGGAGTACGGCGGCGGTGGCGGCGGCATCGGCGACATCGCGGCCGTCTGCGAGGAGCTGGCCGCCCAG
GGCTGCCCGTTGCTGCTGATGGTCGTGAGCCCGGCGATCTGCGGCACGATCATCAGCCGCTACGGCACCCCGGAGCAGAA
GCAGCGCTGGCTGCCCGGCATCTGCGACGGCACCGGCACGATGGCGTTCGCGATCACCGAGCCGGACGCCGGCACCAACA
CCCACAACATCACCACGACCGCGCGGCGGGACGGCGACGGCTGGGTGCTCAGCGGCCGCAAGATCTACATCTCGGGCGTC
GACGAGGCCGACAACATGCTGGTCGTCGCGCGCACCGAGGACGCGCGCACCGGCAAGCTCAAGCCCTGCCTGTTCGTGGT
GCCGACCGACGCCGAGGGCCTCGAGGCCAAGGCGATCGCGATGGAGATCGTCAGCCCCGAGCTGCAGTTCGCGGTGTTCC
TCGACGACGTCCGGCTGCCCGCCGACGCGCTGGTCGGGGACGAGGACGGCGGCCTGGTGCAGCTGTTCGCCGGGCTCAAC
CCGGAGCGGATCATGGCCGCCTCGTTCTCGACCGGCCTGGCCCGGCACGCCCTGGACAAGGCGACGACGTACGCGAAGGA
GCGCACGGTGTTCCAGGGGCCGATCGGGTCGCACCAGGCGATCGCGCACCCGCTCGCGGAGTCGCACATCGAGATCGAGA
TGGCCCGGCTGATGACCCAGAAGGCCGCCGCGCTCTACGACGCGGGCGACGACATGGGCGCCGGCGAGGCCGCGAACATG
GCGAAGTACGCCGCCGCCGAGGCCGCCTGTCACGCCGTCGACCGGGCCGTGCAGACCCACGGCGGCAACGGCATCACCCA
GGAGTACGGCGTGGCCGGGCTCCTGGTCGCCAGCCGCGCGGGCCGGATCGCGCCGGTCAGCCGGGAGATGATCCTCAACT
TCGTCGCGATGCACTCCCTGGGACTGCCCAAGTCCTATTGA

Upstream 100 bases:

>100_bases
ACGCCGGCACGGTCACGGAGATCGACGTCAAGCCCGGTGCGCAGGTCGCCGCCGGGGAGGTTCTGGCCGTGGTGGAGCAG
ACCGTGGAAGAGGAGCAGCA

Downstream 100 bases:

>100_bases
TCCCGGTTGCTGTAACGCCCGGTTACCCCTTCCTCCCACCGTGTTGCAGCAGGGTGGGTAGGTGGGGTAACACGGCGTTA
CAGTTGTCGGCGCACTGTGG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSNFSESQERQELRKAVAKLAAKYGREWFTRKARSGEKTTELWLEIGANGYLGINIPEEYGGGGGGIGDIAAVCEELAAQ
GCPLLLMVVSPAICGTIISRYGTPEQKQRWLPGICDGTGTMAFAITEPDAGTNTHNITTTARRDGDGWVLSGRKIYISGV
DEADNMLVVARTEDARTGKLKPCLFVVPTDAEGLEAKAIAMEIVSPELQFAVFLDDVRLPADALVGDEDGGLVQLFAGLN
PERIMAASFSTGLARHALDKATTYAKERTVFQGPIGSHQAIAHPLAESHIEIEMARLMTQKAAALYDAGDDMGAGEAANM
AKYAAAEAACHAVDRAVQTHGGNGITQEYGVAGLLVASRAGRIAPVSREMILNFVAMHSLGLPKSY

Sequences:

>Translated_386_residues
MSNFSESQERQELRKAVAKLAAKYGREWFTRKARSGEKTTELWLEIGANGYLGINIPEEYGGGGGGIGDIAAVCEELAAQ
GCPLLLMVVSPAICGTIISRYGTPEQKQRWLPGICDGTGTMAFAITEPDAGTNTHNITTTARRDGDGWVLSGRKIYISGV
DEADNMLVVARTEDARTGKLKPCLFVVPTDAEGLEAKAIAMEIVSPELQFAVFLDDVRLPADALVGDEDGGLVQLFAGLN
PERIMAASFSTGLARHALDKATTYAKERTVFQGPIGSHQAIAHPLAESHIEIEMARLMTQKAAALYDAGDDMGAGEAANM
AKYAAAEAACHAVDRAVQTHGGNGITQEYGVAGLLVASRAGRIAPVSREMILNFVAMHSLGLPKSY
>Mature_385_residues
SNFSESQERQELRKAVAKLAAKYGREWFTRKARSGEKTTELWLEIGANGYLGINIPEEYGGGGGGIGDIAAVCEELAAQG
CPLLLMVVSPAICGTIISRYGTPEQKQRWLPGICDGTGTMAFAITEPDAGTNTHNITTTARRDGDGWVLSGRKIYISGVD
EADNMLVVARTEDARTGKLKPCLFVVPTDAEGLEAKAIAMEIVSPELQFAVFLDDVRLPADALVGDEDGGLVQLFAGLNP
ERIMAASFSTGLARHALDKATTYAKERTVFQGPIGSHQAIAHPLAESHIEIEMARLMTQKAAALYDAGDDMGAGEAANMA
KYAAAEAACHAVDRAVQTHGGNGITQEYGVAGLLVASRAGRIAPVSREMILNFVAMHSLGLPKSY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=369, Percent_Identity=30.0813008130081, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI4557233, Length=307, Percent_Identity=34.8534201954397, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI38505218, Length=292, Percent_Identity=31.5068493150685, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI4501859, Length=340, Percent_Identity=30, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI187960098, Length=359, Percent_Identity=32.033426183844, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI4557231, Length=359, Percent_Identity=32.033426183844, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI226958412, Length=354, Percent_Identity=27.683615819209, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7656849, Length=373, Percent_Identity=28.1501340482574, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI226958414, Length=324, Percent_Identity=28.0864197530864, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI211971008, Length=367, Percent_Identity=25.8855585831063, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI48976061, Length=367, Percent_Identity=25.8855585831063, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI76496475, Length=363, Percent_Identity=28.6501377410468, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4557235, Length=363, Percent_Identity=28.6501377410468, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI21361497, Length=386, Percent_Identity=24.6113989637306, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI7669494, Length=272, Percent_Identity=27.5735294117647, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4503943, Length=272, Percent_Identity=27.5735294117647, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI87081958, Length=375, Percent_Identity=28.2666666666667, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1786223, Length=315, Percent_Identity=29.8412698412698, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=331, Percent_Identity=31.4199395770393, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17506239, Length=330, Percent_Identity=30.3030303030303, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17534899, Length=357, Percent_Identity=29.4117647058824, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17570075, Length=363, Percent_Identity=32.5068870523416, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17569725, Length=363, Percent_Identity=28.9256198347107, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17538396, Length=363, Percent_Identity=28.099173553719, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71990804, Length=282, Percent_Identity=30.4964539007092, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17533517, Length=341, Percent_Identity=27.8592375366569, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17505929, Length=311, Percent_Identity=26.6881028938907, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17551932, Length=311, Percent_Identity=25.7234726688103, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=30.6034482758621, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=345, Percent_Identity=28.1159420289855, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=342, Percent_Identity=28.0701754385965, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71982178, Length=233, Percent_Identity=29.6137339055794, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=363, Percent_Identity=26.4462809917355, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17531909, Length=244, Percent_Identity=27.4590163934426, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=245, Percent_Identity=27.7551020408163, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355753, Length=352, Percent_Identity=29.8295454545455, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24666513, Length=354, Percent_Identity=29.9435028248588, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24660351, Length=370, Percent_Identity=30.5405405405405, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281363737, Length=357, Percent_Identity=29.4117647058824, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24646207, Length=305, Percent_Identity=30.1639344262295, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21356377, Length=305, Percent_Identity=30.1639344262295, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19920834, Length=315, Percent_Identity=27.3015873015873, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41013; Mature: 40882

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFSESQERQELRKAVAKLAAKYGREWFTRKARSGEKTTELWLEIGANGYLGINIPEEY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEHEEECCCCEEEEECCHHH
GGGGGGIGDIAAVCEELAAQGCPLLLMVVSPAICGTIISRYGTPEQKQRWLPGICDGTGT
CCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCC
MAFAITEPDAGTNTHNITTTARRDGDGWVLSGRKIYISGVDEADNMLVVARTEDARTGKL
EEEEEECCCCCCCCCCEEEEEEECCCCEEEECCEEEEEECCCCCCEEEEEECCCCCCCCC
KPCLFVVPTDAEGLEAKAIAMEIVSPELQFAVFLDDVRLPADALVGDEDGGLVQLFAGLN
CCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCHHHHCCCCCCCEEEEECCCC
PERIMAASFSTGLARHALDKATTYAKERTVFQGPIGSHQAIAHPLAESHIEIEMARLMTQ
HHHEEEEHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
KAAALYDAGDDMGAGEAANMAKYAAAEAACHAVDRAVQTHGGNGITQEYGVAGLLVASRA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCHHHEEEHHCC
GRIAPVSREMILNFVAMHSLGLPKSY
CCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNFSESQERQELRKAVAKLAAKYGREWFTRKARSGEKTTELWLEIGANGYLGINIPEEY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEHEEECCCCEEEEECCHHH
GGGGGGIGDIAAVCEELAAQGCPLLLMVVSPAICGTIISRYGTPEQKQRWLPGICDGTGT
CCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCC
MAFAITEPDAGTNTHNITTTARRDGDGWVLSGRKIYISGVDEADNMLVVARTEDARTGKL
EEEEEECCCCCCCCCCEEEEEEECCCCEEEECCEEEEEECCCCCCEEEEEECCCCCCCCC
KPCLFVVPTDAEGLEAKAIAMEIVSPELQFAVFLDDVRLPADALVGDEDGGLVQLFAGLN
CCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCHHHHCCCCCCCEEEEECCCC
PERIMAASFSTGLARHALDKATTYAKERTVFQGPIGSHQAIAHPLAESHIEIEMARLMTQ
HHHEEEEHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
KAAALYDAGDDMGAGEAANMAKYAAAEAACHAVDRAVQTHGGNGITQEYGVAGLLVASRA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCHHHEEEHHCC
GRIAPVSREMILNFVAMHSLGLPKSY
CCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]