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The map label for this gene is accA1 [H]

Identifier: 119718770

GI number: 119718770

Start: 4814463

End: 4816364

Strand: Reverse

Name: accA1 [H]

Synonym: Noca_4551

Alternate gene names: 119718770

Gene position: 4816364-4814463 (Counterclockwise)

Preceding gene: 119718771

Following gene: 119718769

Centisome position: 96.6

GC content: 73.08

Gene sequence:

>1902_bases
GTGATCACCAGACTGCTGGTCGCCAACCGTGCCGAGATCGCCTCACGGGTGTTCCGCACCTGTCGCGGGCTCGGCATCGA
GACGGTCGCGATCCACTCGGACGCGGACGCCGACCTGCCCTACGTGCGGGAGGCGGACCACGCCGTCCGCCTGCCCGGTA
ACGCGCCGGCCGAGACGTACCTGCGCATCGACCTGGTGCTCGACGCCGCGCGCCGCTCCGGCGCCGACGCGATCCACCCG
GGCTACGGCTTCCTCTCCGAGAACGCGGAGTTCGCACGCGCCGTGATCGACGCCGGCCTGACCTGGATCGGCCCGGCCCC
GGAGTCGATCGAGGCGATGGGCTCGAAGATCCGCGCCAAGGAGATCATGAAGGCGGCCGGAGTGCCGGTGCTGGAGGCGC
CGGCCGAGCCGGCCGAGGCCGACCTCCCGCTGCTGGTCAAGGCCTCGGCGGGCGGGGGCGGCCGGGGGATGCGCGTCGTG
CGCACCCTCGCCGACCTGCCCGGCGAGATCGAGAAGGCCCGGGCCGAGGCGGCGTCGGCGTTCGGCGACGGCACCGTCTT
CGTCGAGCCGTACGTCGAGCACGGGCGGCACGTCGAGGTCCAGGTCCTCGGCACCAGCGTGTTCGGCGACCGCGACTGCT
CCCTGCAGCGCCGCCACCAGAAGGTCGTCGAGGAGGCCCCGGCACCCGGCCTCAGCGACGAGGTGCGTGCCGCCCTGCAC
GACGCCGCTCGTCACGCCGCCGAGGCGATCGAGTACCGCAGCGCCGGCACCGTCGAGTTCCTCTACGACCCGGCCACCGA
GCGGTTCTGGTTCCTGGAGATGAACACCCGGCTCCAGGTCGAGCACCCGGTCACCGAGCTGGTGCACGACGTCGACCTGG
TGGCGTTGCAGATCCGCGACGCCGAGGCGAGCTGGTTCATGGGCTGGCCGGACCCACCGCGCAGCCACGCGATCGAGGTG
CGTCTGTACGCCGAGGATCCGGCGGCCGACTACCAGCCGCAGAGTGGCCGGCTGACCACCTTCGAGATCCCCCAGGAGGA
GGGCATCCGGGTCGACGCCGGCTTCGAGTCCGGCAGCGAGGTGTCGACGCACTACGACGCGATGCTGGCCAAGGTGATCG
CGCACGCGCCGACCCGGCAGGCCGCCGCCCGCAGGCTCGCGAGCGTGCTGAGCCGCGCGCGGATCCACGGTGTGGTCACC
AACCGGGACCAGCTCGTCCGGGTGCTGCGCGACCCGGCGTTCCTCCGCGGGGACGTGAGCACCGACTTCCTGGGTCGTGT
GTCCGAGAGTGCGCCGGAGCGCACGGTGGACAGCACGACCCCGGCCGCGGTCGCGGCGGCGATCGCGCTGGCCGAGCAGG
CGGTGGCGGACCGCACCGTCCAGCGCGGCATCCCGGTCGCCTGGCGCAACGTCGTCTCCCAGCCGCAGCGCACCGAGTTC
GAGGGTGACGTCGTCGTGGAGTGGTGGGGCGGGCGTGACGGCTACCGGCTCGACGGCCACACGGTGGTCGCCGCGAGCCC
GACCGGCGTCACCTTGGAGGCCGACGGCGTGCGCACGACGTACGTGGTCGCTGTCAACGGAGCCGATGTCGACGTCGACA
GCCCACGCGGCCACGTCCGGCTGACCCGGGTGCCGCGGTTCGTGGACCCGGCCGAGCAGGTCGCCAGCGGCAGCCTGCTG
GCGCCGATGCCGGGCACGGTCGTCAGCGTCGCGGTCGAGGCGGGCCAGCAGGTCGGGGCGGGCCAGTCGGTGCTGGTCCT
CGAGGCGATGAAGATGCAGCACACCGTGAGCGCGCCGTACGCCGGCACGGTCACGGAGATCGACGTCAAGCCCGGTGCGC
AGGTCGCCGCCGGGGAGGTTCTGGCCGTGGTGGAGCAGACCGTGGAAGAGGAGCAGCAGTGA

Upstream 100 bases:

>100_bases
CTTCGCCGCGGCCCTTGTCTGTTCCGTCGGACCAGGGGCTCCTTCGTCGCCCGGTTCGACGGTCGAACGCTCGCAAGCTC
GCATTCGAGGAGGTGTCGTC

Downstream 100 bases:

>100_bases
GCAACTTCAGCGAGTCCCAGGAGCGCCAGGAGCTCCGCAAGGCCGTGGCCAAGCTGGCCGCCAAGTACGGTCGCGAGTGG
TTCACCCGGAAGGCGCGCAG

Product: carbamoyl-phosphate synthase L chain, ATP-binding

Products: NA

Alternate protein names: Biotin carboxylase; Biotin carboxyl carrier protein; BCCP [H]

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MITRLLVANRAEIASRVFRTCRGLGIETVAIHSDADADLPYVREADHAVRLPGNAPAETYLRIDLVLDAARRSGADAIHP
GYGFLSENAEFARAVIDAGLTWIGPAPESIEAMGSKIRAKEIMKAAGVPVLEAPAEPAEADLPLLVKASAGGGGRGMRVV
RTLADLPGEIEKARAEAASAFGDGTVFVEPYVEHGRHVEVQVLGTSVFGDRDCSLQRRHQKVVEEAPAPGLSDEVRAALH
DAARHAAEAIEYRSAGTVEFLYDPATERFWFLEMNTRLQVEHPVTELVHDVDLVALQIRDAEASWFMGWPDPPRSHAIEV
RLYAEDPAADYQPQSGRLTTFEIPQEEGIRVDAGFESGSEVSTHYDAMLAKVIAHAPTRQAAARRLASVLSRARIHGVVT
NRDQLVRVLRDPAFLRGDVSTDFLGRVSESAPERTVDSTTPAAVAAAIALAEQAVADRTVQRGIPVAWRNVVSQPQRTEF
EGDVVVEWWGGRDGYRLDGHTVVAASPTGVTLEADGVRTTYVVAVNGADVDVDSPRGHVRLTRVPRFVDPAEQVASGSLL
APMPGTVVSVAVEAGQQVGAGQSVLVLEAMKMQHTVSAPYAGTVTEIDVKPGAQVAAGEVLAVVEQTVEEEQQ

Sequences:

>Translated_633_residues
MITRLLVANRAEIASRVFRTCRGLGIETVAIHSDADADLPYVREADHAVRLPGNAPAETYLRIDLVLDAARRSGADAIHP
GYGFLSENAEFARAVIDAGLTWIGPAPESIEAMGSKIRAKEIMKAAGVPVLEAPAEPAEADLPLLVKASAGGGGRGMRVV
RTLADLPGEIEKARAEAASAFGDGTVFVEPYVEHGRHVEVQVLGTSVFGDRDCSLQRRHQKVVEEAPAPGLSDEVRAALH
DAARHAAEAIEYRSAGTVEFLYDPATERFWFLEMNTRLQVEHPVTELVHDVDLVALQIRDAEASWFMGWPDPPRSHAIEV
RLYAEDPAADYQPQSGRLTTFEIPQEEGIRVDAGFESGSEVSTHYDAMLAKVIAHAPTRQAAARRLASVLSRARIHGVVT
NRDQLVRVLRDPAFLRGDVSTDFLGRVSESAPERTVDSTTPAAVAAAIALAEQAVADRTVQRGIPVAWRNVVSQPQRTEF
EGDVVVEWWGGRDGYRLDGHTVVAASPTGVTLEADGVRTTYVVAVNGADVDVDSPRGHVRLTRVPRFVDPAEQVASGSLL
APMPGTVVSVAVEAGQQVGAGQSVLVLEAMKMQHTVSAPYAGTVTEIDVKPGAQVAAGEVLAVVEQTVEEEQQ
>Mature_633_residues
MITRLLVANRAEIASRVFRTCRGLGIETVAIHSDADADLPYVREADHAVRLPGNAPAETYLRIDLVLDAARRSGADAIHP
GYGFLSENAEFARAVIDAGLTWIGPAPESIEAMGSKIRAKEIMKAAGVPVLEAPAEPAEADLPLLVKASAGGGGRGMRVV
RTLADLPGEIEKARAEAASAFGDGTVFVEPYVEHGRHVEVQVLGTSVFGDRDCSLQRRHQKVVEEAPAPGLSDEVRAALH
DAARHAAEAIEYRSAGTVEFLYDPATERFWFLEMNTRLQVEHPVTELVHDVDLVALQIRDAEASWFMGWPDPPRSHAIEV
RLYAEDPAADYQPQSGRLTTFEIPQEEGIRVDAGFESGSEVSTHYDAMLAKVIAHAPTRQAAARRLASVLSRARIHGVVT
NRDQLVRVLRDPAFLRGDVSTDFLGRVSESAPERTVDSTTPAAVAAAIALAEQAVADRTVQRGIPVAWRNVVSQPQRTEF
EGDVVVEWWGGRDGYRLDGHTVVAASPTGVTLEADGVRTTYVVAVNGADVDVDSPRGHVRLTRVPRFVDPAEQVASGSLL
APMPGTVVSVAVEAGQQVGAGQSVLVLEAMKMQHTVSAPYAGTVTEIDVKPGAQVAAGEVLAVVEQTVEEEQQ

Specific function: This protein carries two functions:biotin carboxyl carrier protein and biotin carboxyltransferase [H]

COG id: COG4770

COG function: function code I; Acetyl/propionyl-CoA carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=671, Percent_Identity=37.8539493293592, Blast_Score=403, Evalue=1e-112,
Organism=Homo sapiens, GI189095269, Length=686, Percent_Identity=37.0262390670554, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI65506442, Length=686, Percent_Identity=37.0262390670554, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI295821183, Length=654, Percent_Identity=37.3088685015291, Blast_Score=360, Evalue=3e-99,
Organism=Homo sapiens, GI106049528, Length=449, Percent_Identity=43.652561247216, Blast_Score=320, Evalue=3e-87,
Organism=Homo sapiens, GI106049295, Length=449, Percent_Identity=43.652561247216, Blast_Score=320, Evalue=3e-87,
Organism=Homo sapiens, GI106049292, Length=449, Percent_Identity=43.652561247216, Blast_Score=320, Evalue=3e-87,
Organism=Homo sapiens, GI38679974, Length=738, Percent_Identity=26.8292682926829, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI38679960, Length=738, Percent_Identity=26.8292682926829, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI38679971, Length=738, Percent_Identity=26.8292682926829, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI38679977, Length=738, Percent_Identity=26.8292682926829, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI38679967, Length=738, Percent_Identity=26.8292682926829, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI134142062, Length=715, Percent_Identity=26.4335664335664, Blast_Score=207, Evalue=3e-53,
Organism=Escherichia coli, GI1789654, Length=444, Percent_Identity=43.9189189189189, Blast_Score=325, Evalue=4e-90,
Organism=Caenorhabditis elegans, GI71987519, Length=661, Percent_Identity=40.393343419062, Blast_Score=401, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17567343, Length=683, Percent_Identity=36.7496339677892, Blast_Score=358, Evalue=3e-99,
Organism=Caenorhabditis elegans, GI17562816, Length=446, Percent_Identity=41.9282511210762, Blast_Score=294, Evalue=7e-80,
Organism=Caenorhabditis elegans, GI71997168, Length=512, Percent_Identity=28.3203125, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI133931226, Length=511, Percent_Identity=27.7886497064579, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71997163, Length=536, Percent_Identity=27.4253731343284, Blast_Score=179, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6319685, Length=442, Percent_Identity=41.1764705882353, Blast_Score=345, Evalue=8e-96,
Organism=Saccharomyces cerevisiae, GI6319695, Length=447, Percent_Identity=39.8210290827741, Blast_Score=281, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6321376, Length=447, Percent_Identity=41.6107382550336, Blast_Score=279, Evalue=7e-76,
Organism=Saccharomyces cerevisiae, GI6323863, Length=680, Percent_Identity=27.2058823529412, Blast_Score=215, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6324343, Length=744, Percent_Identity=25.6720430107527, Blast_Score=209, Evalue=8e-55,
Organism=Drosophila melanogaster, GI24651757, Length=679, Percent_Identity=37.7025036818851, Blast_Score=386, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24651759, Length=636, Percent_Identity=37.1069182389937, Blast_Score=345, Evalue=6e-95,
Organism=Drosophila melanogaster, GI24652212, Length=446, Percent_Identity=44.3946188340807, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652210, Length=446, Percent_Identity=44.3946188340807, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652214, Length=446, Percent_Identity=44.3946188340807, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI19921944, Length=446, Percent_Identity=44.3946188340807, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652216, Length=446, Percent_Identity=44.3946188340807, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI281363050, Length=446, Percent_Identity=44.3946188340807, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652224, Length=446, Percent_Identity=44.3946188340807, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652222, Length=446, Percent_Identity=44.3946188340807, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652220, Length=446, Percent_Identity=44.3946188340807, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652218, Length=446, Percent_Identity=44.3946188340807, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI161076407, Length=713, Percent_Identity=27.9102384291725, Blast_Score=223, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24586460, Length=713, Percent_Identity=27.9102384291725, Blast_Score=223, Evalue=4e-58,
Organism=Drosophila melanogaster, GI161076409, Length=713, Percent_Identity=27.9102384291725, Blast_Score=223, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24586458, Length=713, Percent_Identity=27.9102384291725, Blast_Score=222, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR001882
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14 [H]

Molecular weight: Translated: 67936; Mature: 67936

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITRLLVANRAEIASRVFRTCRGLGIETVAIHSDADADLPYVREADHAVRLPGNAPAETY
CCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCE
LRIDLVLDAARRSGADAIHPGYGFLSENAEFARAVIDAGLTWIGPAPESIEAMGSKIRAK
EEEEEEEEHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHH
EIMKAAGVPVLEAPAEPAEADLPLLVKASAGGGGRGMRVVRTLADLPGEIEKARAEAASA
HHHHHCCCCEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
FGDGTVFVEPYVEHGRHVEVQVLGTSVFGDRDCSLQRRHQKVVEEAPAPGLSDEVRAALH
CCCCEEEEEEHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
DAARHAAEAIEYRSAGTVEFLYDPATERFWFLEMNTRLQVEHPVTELVHDVDLVALQIRD
HHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCEEEECCCHHHHHHHCEEEEEEEEC
AEASWFMGWPDPPRSHAIEVRLYAEDPAADYQPQSGRLTTFEIPQEEGIRVDAGFESGSE
CCCCEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCHHCCCEEECCCCCCCC
VSTHYDAMLAKVIAHAPTRQAAARRLASVLSRARIHGVVTNRDQLVRVLRDPAFLRGDVS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCEECCCC
TDFLGRVSESAPERTVDSTTPAAVAAAIALAEQAVADRTVQRGIPVAWRNVVSQPQRTEF
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC
EGDVVVEWWGGRDGYRLDGHTVVAASPTGVTLEADGVRTTYVVAVNGADVDVDSPRGHVR
CCCEEEEEECCCCCEEECCEEEEEECCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCEE
LTRVPRFVDPAEQVASGSLLAPMPGTVVSVAVEAGQQVGAGQSVLVLEAMKMQHTVSAPY
EECCCCCCCHHHHHHCCCEECCCCCHHHHHHHHHCHHCCCCCEEEHHHHHHHHHHCCCCC
AGTVTEIDVKPGAQVAAGEVLAVVEQTVEEEQQ
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITRLLVANRAEIASRVFRTCRGLGIETVAIHSDADADLPYVREADHAVRLPGNAPAETY
CCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCE
LRIDLVLDAARRSGADAIHPGYGFLSENAEFARAVIDAGLTWIGPAPESIEAMGSKIRAK
EEEEEEEEHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHH
EIMKAAGVPVLEAPAEPAEADLPLLVKASAGGGGRGMRVVRTLADLPGEIEKARAEAASA
HHHHHCCCCEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
FGDGTVFVEPYVEHGRHVEVQVLGTSVFGDRDCSLQRRHQKVVEEAPAPGLSDEVRAALH
CCCCEEEEEEHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
DAARHAAEAIEYRSAGTVEFLYDPATERFWFLEMNTRLQVEHPVTELVHDVDLVALQIRD
HHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCEEEECCCHHHHHHHCEEEEEEEEC
AEASWFMGWPDPPRSHAIEVRLYAEDPAADYQPQSGRLTTFEIPQEEGIRVDAGFESGSE
CCCCEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCHHCCCEEECCCCCCCC
VSTHYDAMLAKVIAHAPTRQAAARRLASVLSRARIHGVVTNRDQLVRVLRDPAFLRGDVS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCEECCCC
TDFLGRVSESAPERTVDSTTPAAVAAAIALAEQAVADRTVQRGIPVAWRNVVSQPQRTEF
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC
EGDVVVEWWGGRDGYRLDGHTVVAASPTGVTLEADGVRTTYVVAVNGADVDVDSPRGHVR
CCCEEEEEECCCCCEEECCEEEEEECCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCEE
LTRVPRFVDPAEQVASGSLLAPMPGTVVSVAVEAGQQVGAGQSVLVLEAMKMQHTVSAPY
EECCCCCCCHHHHHHCCCEECCCCCHHHHHHHHHCHHCCCCCEEEHHHHHHHHHHCCCCC
AGTVTEIDVKPGAQVAAGEVLAVVEQTVEEEQQ
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]