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The map label for this gene is dinB2 [H]

Identifier: 119718768

GI number: 119718768

Start: 4811925

End: 4813184

Strand: Reverse

Name: dinB2 [H]

Synonym: Noca_4549

Alternate gene names: 119718768

Gene position: 4813184-4811925 (Counterclockwise)

Preceding gene: 119718769

Following gene: 119718767

Centisome position: 96.54

GC content: 74.84

Gene sequence:

>1260_bases
GTGTTCGATACTGGCCTGGTGGGACGGATCGCGAGCAGGGCCGAGGCGAGCATCCTGCACGCCGACCTGGACTCGTTCTT
CGCCTCGGTCGAGCAGCGCGACGATCCACGGCTGCGCGGCCGGCCGGTGATCGTCGGCGGCGGGGTGGTCCTGGCCGCGA
GCTACGAGGCCAAGGCGTTCGGGGTGCGCTCGGCGATGGGTGGGCGCGAGGCCGCGCGGCGCTGTCCGGATGCGCTGGTG
GTGCCACCGCGGTTCTCGGCGTACGTCGAGGCCAGCAAGCAGGTCTTCGCGATCTTCGAGGACACCACGCCGCTGGTCGA
GGGGATCTCGATCGACGAGGCGTTCCTCGACGTCGGGGGGCTGCGCCGGCTGGTCGGCCCGCCCGAGCAGATCGGCCGCG
GCCTGCGGGCCCGGGTGAAGGACGAGGTCGGGCTGCCGATCTCGGTCGGGATCGCGCGCACCAAGTACCTCGCGAAGGTC
GCGAGCGCGGTGTCCAAGCCCGACGGGCTGCTCGCGGTGTCGCCCGACGGCGAGCAGGCGTTCCTCCACCCGCTGCCGGT
CGAGCGGCTCTGGGGGGTCGGTGCGGTCACGGCGGCCAAGCTGCACGCGGAAGGCATCCGCAGCATCGGCGAGCTCGCGG
CCCGCGAGGAGGTCGAGCTGACCGCGACCGTCGGCCGGGCCGCCGGCCGGCACCTGTGGGCGCTGGCGAACCTGCTCGAC
CCGCGCCCGGTCGAGGTGGGCCGGCGGCGCCGCTCGATCGGCTCGCAGTGCGCGATCGGCCGGCCCGGGAGACCGAAGAG
CCGCGGCGACCTGGAGGCGCTGCTGGCCGGTCTGGTCGACCGGGTGGCCCGCCGGCTGCGGGCGGGGGAACGGATCGGCC
AGACGTTCACGCTCCGGCTCCGGTTCGACGACTTCAGCCGAGCGACCCGCTCCGCGACGCTGGCACACTCGACCGCGACC
ACCGCGACCTGGCTGGAGACCGGGCGGCGACTGCTCGCCGCCAGCTGGCCGCTCATCGAGGAGCGCGGCTGCACCCTCCT
CGGTGTCACGATCTCCGGGCTGGTCGACGGCCGGTCCCAGCAGCTCGAGCTGCCGCTGTTCCCCGACACCGTGCACGAGC
ACGGCCTCGACGCCGCGCTCGACCGGGTCCGCGACCGGTTCGGCTCGGCGTCGGTGACCCGGGCGGTCCTGGTCGGTCGG
CGCACCGGCCTCGAGATGCCCACGCTCCCCGACCCCGGGCCGCCGACGCCGGTACCGTGA

Upstream 100 bases:

>100_bases
GTTACCCCTTCCTCCCACCGTGTTGCAGCAGGGTGGGTAGGTGGGGTAACACGGCGTTACAGTTGTCGGCGCACTGTGGC
CGCTCGACAGCGCCGAACAT

Downstream 100 bases:

>100_bases
GCGGGTGGGCAGGGCACTGGACGCCGTCGACCGCGGGCAGCGCCGCTTCCCGCCGATCGCCGTACCCCTCGCCGTGATCT
ACAAGTACTCCGACGACCAG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 2 [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MFDTGLVGRIASRAEASILHADLDSFFASVEQRDDPRLRGRPVIVGGGVVLAASYEAKAFGVRSAMGGREAARRCPDALV
VPPRFSAYVEASKQVFAIFEDTTPLVEGISIDEAFLDVGGLRRLVGPPEQIGRGLRARVKDEVGLPISVGIARTKYLAKV
ASAVSKPDGLLAVSPDGEQAFLHPLPVERLWGVGAVTAAKLHAEGIRSIGELAAREEVELTATVGRAAGRHLWALANLLD
PRPVEVGRRRRSIGSQCAIGRPGRPKSRGDLEALLAGLVDRVARRLRAGERIGQTFTLRLRFDDFSRATRSATLAHSTAT
TATWLETGRRLLAASWPLIEERGCTLLGVTISGLVDGRSQQLELPLFPDTVHEHGLDAALDRVRDRFGSASVTRAVLVGR
RTGLEMPTLPDPGPPTPVP

Sequences:

>Translated_419_residues
MFDTGLVGRIASRAEASILHADLDSFFASVEQRDDPRLRGRPVIVGGGVVLAASYEAKAFGVRSAMGGREAARRCPDALV
VPPRFSAYVEASKQVFAIFEDTTPLVEGISIDEAFLDVGGLRRLVGPPEQIGRGLRARVKDEVGLPISVGIARTKYLAKV
ASAVSKPDGLLAVSPDGEQAFLHPLPVERLWGVGAVTAAKLHAEGIRSIGELAAREEVELTATVGRAAGRHLWALANLLD
PRPVEVGRRRRSIGSQCAIGRPGRPKSRGDLEALLAGLVDRVARRLRAGERIGQTFTLRLRFDDFSRATRSATLAHSTAT
TATWLETGRRLLAASWPLIEERGCTLLGVTISGLVDGRSQQLELPLFPDTVHEHGLDAALDRVRDRFGSASVTRAVLVGR
RTGLEMPTLPDPGPPTPVP
>Mature_419_residues
MFDTGLVGRIASRAEASILHADLDSFFASVEQRDDPRLRGRPVIVGGGVVLAASYEAKAFGVRSAMGGREAARRCPDALV
VPPRFSAYVEASKQVFAIFEDTTPLVEGISIDEAFLDVGGLRRLVGPPEQIGRGLRARVKDEVGLPISVGIARTKYLAKV
ASAVSKPDGLLAVSPDGEQAFLHPLPVERLWGVGAVTAAKLHAEGIRSIGELAAREEVELTATVGRAAGRHLWALANLLD
PRPVEVGRRRRSIGSQCAIGRPGRPKSRGDLEALLAGLVDRVARRLRAGERIGQTFTLRLRFDDFSRATRSATLAHSTAT
TATWLETGRRLLAASWPLIEERGCTLLGVTISGLVDGRSQQLELPLFPDTVHEHGLDAALDRVRDRFGSASVTRAVLVGR
RTGLEMPTLPDPGPPTPVP

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=272, Percent_Identity=29.4117647058824, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI84043967, Length=272, Percent_Identity=29.4117647058824, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI154350220, Length=307, Percent_Identity=27.6872964169381, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI7705344, Length=119, Percent_Identity=42.8571428571429, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI5729982, Length=149, Percent_Identity=33.5570469798658, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786425, Length=306, Percent_Identity=37.5816993464052, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1787432, Length=205, Percent_Identity=34.6341463414634, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17537959, Length=301, Percent_Identity=26.9102990033223, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI193205700, Length=402, Percent_Identity=27.8606965174129, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115534089, Length=118, Percent_Identity=38.9830508474576, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193205702, Length=319, Percent_Identity=29.7805642633229, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19923006, Length=340, Percent_Identity=24.4117647058824, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21355641, Length=337, Percent_Identity=26.1127596439169, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24644984, Length=337, Percent_Identity=26.1127596439169, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24668444, Length=123, Percent_Identity=34.1463414634146, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 44911; Mature: 44911

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTGLVGRIASRAEASILHADLDSFFASVEQRDDPRLRGRPVIVGGGVVLAASYEAKAF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEECCCHHHH
GVRSAMGGREAARRCPDALVVPPRFSAYVEASKQVFAIFEDTTPLVEGISIDEAFLDVGG
HHHHHCCCHHHHHHCCCCEEECCCHHHHHHCCCEEEEEECCCCHHHHCCCHHHHHHHHHH
LRRLVGPPEQIGRGLRARVKDEVGLPISVGIARTKYLAKVASAVSKPDGLLAVSPDGEQA
HHHHCCCHHHHCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEECCCCCCE
FLHPLPVERLWGVGAVTAAKLHAEGIRSIGELAAREEVELTATVGRAAGRHLWALANLLD
EECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHCC
PRPVEVGRRRRSIGSQCAIGRPGRPKSRGDLEALLAGLVDRVARRLRAGERIGQTFTLRL
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
RFDDFSRATRSATLAHSTATTATWLETGRRLLAASWPLIEERGCTLLGVTISGLVDGRSQ
EECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHCCCEEEEEEEEHHCCCCCC
QLELPLFPDTVHEHGLDAALDRVRDRFGSASVTRAVLVGRRTGLEMPTLPDPGPPTPVP
EEECCCCCCHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFDTGLVGRIASRAEASILHADLDSFFASVEQRDDPRLRGRPVIVGGGVVLAASYEAKAF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEECCCHHHH
GVRSAMGGREAARRCPDALVVPPRFSAYVEASKQVFAIFEDTTPLVEGISIDEAFLDVGG
HHHHHCCCHHHHHHCCCCEEECCCHHHHHHCCCEEEEEECCCCHHHHCCCHHHHHHHHHH
LRRLVGPPEQIGRGLRARVKDEVGLPISVGIARTKYLAKVASAVSKPDGLLAVSPDGEQA
HHHHCCCHHHHCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEECCCCCCE
FLHPLPVERLWGVGAVTAAKLHAEGIRSIGELAAREEVELTATVGRAAGRHLWALANLLD
EECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHCC
PRPVEVGRRRRSIGSQCAIGRPGRPKSRGDLEALLAGLVDRVARRLRAGERIGQTFTLRL
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
RFDDFSRATRSATLAHSTATTATWLETGRRLLAASWPLIEERGCTLLGVTISGLVDGRSQ
EECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHCCCEEEEEEEEHHCCCCCC
QLELPLFPDTVHEHGLDAALDRVRDRFGSASVTRAVLVGRRTGLEMPTLPDPGPPTPVP
EEECCCCCCHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]