Click here to switch to the map view.

The map label for this gene is cmcT [H]

Identifier: 119718711

GI number: 119718711

Start: 4749317

End: 4750780

Strand: Reverse

Name: cmcT [H]

Synonym: Noca_4492

Alternate gene names: 119718711

Gene position: 4750780-4749317 (Counterclockwise)

Preceding gene: 119718712

Following gene: 119718710

Centisome position: 95.28

GC content: 73.5

Gene sequence:

>1464_bases
ATGACCGACCTGAAGAGCCGCTGGCTCGCGCTGTACGTGCTGTGCCTGGGCGACCTGATGATCGTGCTGGACTCCAGCAT
CGTGAACGTCGCGCTGCCGTCGATCCAGGCCGACCTGGGGTTCACCCGGTCGGCGCTGGCCTGGGTGGTCAATGCGTACC
TGCTGACCTTCGGCGGCTTCCTGCTGCTCTCCGGGCGCCTGGGCGACCTGCTGGGCAACAAGCGGGTCTTCCTCGGCGGC
GTGGTGTCCTTCACCGTCGCGTCGGTCGCGTGCGGCCTCGCGCCGTCCTCCGGGCTGCTCGTCGTGGGCCGCGCCGTGCA
GGGCCTGGGCGGCGCCGCGGTCTCCGCGGTCGCGCTCTCGCTGATCATGGGGCTGTTCTCCGACCCGGCCGAGCGGGCCC
GGGCGATGGGCTTCTTCGGCTTCGTGATGTCCGGGGGCGGCGCCGTCGGGGTGCTGCTCGGCGGCGTCCTGACCGGGCTG
TTCTCGTGGCACTGGATCTTCCTGGTGAACGTGCCCATCGGCGTCGGGGTCTGGCTGGCCGCGCGCCGGGTGCTGCCCGC
CGACGAGGTCGTGCCGGGCGCGGGGCGACTCGATGTCCCCGGGGCGGTGCTGGTGACCGCCGCGCTGATGCTGAGCGTGT
ACGGGATCGTCGGCGGCAACGAGGCGGGGTGGACCTCCGGGCGCACGCTCGGTCTGCTCGGCGCCAGCGCGGTGCTGCTC
GCGGCGTTCGTGCTCCGCGAGGCGCGCGCCGCCAGCCCGCTGGTCCCGCTGCGCCTGTTCGCGCTGCGCAACGTCTCCGT
GTCGCAGGTGGTGGGGATGCTGTGGGCGGCCGCGATGTTCGCGTGGTTCTTCCTGGCCGCGCTCTACCTTCAGCAGGTGC
TGGGGTACGACGCCCTCGAGGTCGGCCTCGCGTTCGTCCCGACCAGCGTGGTGATGGCGTTCTGCTCGCTGCGGGTCTCC
GACCGGCTGGTCATGCGCTTCGGCATCCGCCGGCCGCTGATGGCCGGGCTCGCGCTCGCCGCCGCCAGCCTGGCGCTGTT
CTCGCGGGCCCCGGTGGACGGCAGCTTCGGGACCGACGTACTGCCCTCGATGCTGCTGCTCGGCGCCGGCGCGGGCATCG
CGTTCAACCCGGTGCTGCTCGCCGCGATGGGCGACGTCGAGCCGCACGAGTCCGGCCTCGCCTCCGGCGTCGTCAACACC
TCGTTCATGATGGGCGGCGCGCTCGGCCTGGCGGTGCTGGTCAGCCTCTCCACCTGGCGCACCGAGTCGCTCGCCGCCGA
CGGAGCCGACCGCCTCGAGGCCCTCAACGGCGGCTTCCAGTTCGCCTTCGCCACCGGCGCGCTCGCCGCCCTCGCGGCGG
CCGTCATCGGCGGCCTGCTCCTCCGCCCCAAGCCGATGGGCGGCGCGGAGCTCGACGCGGTCGCGATCGCCGACGAGCCC
ACCCTCGACGCGAGCCTCGGATAG

Upstream 100 bases:

>100_bases
CCACGTCTGATGCGATGAGAACAACGTTCCCGCCCGGTCTGTCGATCTCGTAGTGCCCCGTTCGTGGAGAGGGTGACCCC
CTTCCACCGAGGAGACCGAG

Downstream 100 bases:

>100_bases
TCCCTGACGATCACGGGGTCTGGGAGCGCTCCCACACCGCGCAAACGTCAGGGACTACCGCTCGCGGCGTCGGCCCGACG
ATGGCCTACCGTTCCGCGGG

Product: EmrB/QacA family drug resistance transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MTDLKSRWLALYVLCLGDLMIVLDSSIVNVALPSIQADLGFTRSALAWVVNAYLLTFGGFLLLSGRLGDLLGNKRVFLGG
VVSFTVASVACGLAPSSGLLVVGRAVQGLGGAAVSAVALSLIMGLFSDPAERARAMGFFGFVMSGGGAVGVLLGGVLTGL
FSWHWIFLVNVPIGVGVWLAARRVLPADEVVPGAGRLDVPGAVLVTAALMLSVYGIVGGNEAGWTSGRTLGLLGASAVLL
AAFVLREARAASPLVPLRLFALRNVSVSQVVGMLWAAAMFAWFFLAALYLQQVLGYDALEVGLAFVPTSVVMAFCSLRVS
DRLVMRFGIRRPLMAGLALAAASLALFSRAPVDGSFGTDVLPSMLLLGAGAGIAFNPVLLAAMGDVEPHESGLASGVVNT
SFMMGGALGLAVLVSLSTWRTESLAADGADRLEALNGGFQFAFATGALAALAAAVIGGLLLRPKPMGGAELDAVAIADEP
TLDASLG

Sequences:

>Translated_487_residues
MTDLKSRWLALYVLCLGDLMIVLDSSIVNVALPSIQADLGFTRSALAWVVNAYLLTFGGFLLLSGRLGDLLGNKRVFLGG
VVSFTVASVACGLAPSSGLLVVGRAVQGLGGAAVSAVALSLIMGLFSDPAERARAMGFFGFVMSGGGAVGVLLGGVLTGL
FSWHWIFLVNVPIGVGVWLAARRVLPADEVVPGAGRLDVPGAVLVTAALMLSVYGIVGGNEAGWTSGRTLGLLGASAVLL
AAFVLREARAASPLVPLRLFALRNVSVSQVVGMLWAAAMFAWFFLAALYLQQVLGYDALEVGLAFVPTSVVMAFCSLRVS
DRLVMRFGIRRPLMAGLALAAASLALFSRAPVDGSFGTDVLPSMLLLGAGAGIAFNPVLLAAMGDVEPHESGLASGVVNT
SFMMGGALGLAVLVSLSTWRTESLAADGADRLEALNGGFQFAFATGALAALAAAVIGGLLLRPKPMGGAELDAVAIADEP
TLDASLG
>Mature_486_residues
TDLKSRWLALYVLCLGDLMIVLDSSIVNVALPSIQADLGFTRSALAWVVNAYLLTFGGFLLLSGRLGDLLGNKRVFLGGV
VSFTVASVACGLAPSSGLLVVGRAVQGLGGAAVSAVALSLIMGLFSDPAERARAMGFFGFVMSGGGAVGVLLGGVLTGLF
SWHWIFLVNVPIGVGVWLAARRVLPADEVVPGAGRLDVPGAVLVTAALMLSVYGIVGGNEAGWTSGRTLGLLGASAVLLA
AFVLREARAASPLVPLRLFALRNVSVSQVVGMLWAAAMFAWFFLAALYLQQVLGYDALEVGLAFVPTSVVMAFCSLRVSD
RLVMRFGIRRPLMAGLALAAASLALFSRAPVDGSFGTDVLPSMLLLGAGAGIAFNPVLLAAMGDVEPHESGLASGVVNTS
FMMGGALGLAVLVSLSTWRTESLAADGADRLEALNGGFQFAFATGALAALAAAVIGGLLLRPKPMGGAELDAVAIADEPT
LDASLG

Specific function: Involved in cephamycin export [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=426, Percent_Identity=32.8638497652582, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1789042, Length=431, Percent_Identity=26.6821345707657, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790195, Length=486, Percent_Identity=28.8065843621399, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788710, Length=432, Percent_Identity=26.6203703703704, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788392, Length=343, Percent_Identity=30.0291545189504, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790146, Length=165, Percent_Identity=29.0909090909091, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324954, Length=434, Percent_Identity=25.3456221198157, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6319770, Length=276, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6325455, Length=235, Percent_Identity=27.2340425531915, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323520, Length=478, Percent_Identity=23.8493723849372, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322958, Length=381, Percent_Identity=24.4094488188976, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321663, Length=152, Percent_Identity=29.6052631578947, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49809; Mature: 49678

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLKSRWLALYVLCLGDLMIVLDSSIVNVALPSIQADLGFTRSALAWVVNAYLLTFGGF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHH
LLLSGRLGDLLGNKRVFLGGVVSFTVASVACGLAPSSGLLVVGRAVQGLGGAAVSAVALS
HHCCCCHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCHHHHHHHHHH
LIMGLFSDPAERARAMGFFGFVMSGGGAVGVLLGGVLTGLFSWHWIFLVNVPIGVGVWLA
HHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHH
ARRVLPADEVVPGAGRLDVPGAVLVTAALMLSVYGIVGGNEAGWTSGRTLGLLGASAVLL
HHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
AAFVLREARAASPLVPLRLFALRNVSVSQVVGMLWAAAMFAWFFLAALYLQQVLGYDALE
HHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VGLAFVPTSVVMAFCSLRVSDRLVMRFGIRRPLMAGLALAAASLALFSRAPVDGSFGTDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LPSMLLLGAGAGIAFNPVLLAAMGDVEPHESGLASGVVNTSFMMGGALGLAVLVSLSTWR
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TESLAADGADRLEALNGGFQFAFATGALAALAAAVIGGLLLRPKPMGGAELDAVAIADEP
CHHHHCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCC
TLDASLG
CCCCCCC
>Mature Secondary Structure 
TDLKSRWLALYVLCLGDLMIVLDSSIVNVALPSIQADLGFTRSALAWVVNAYLLTFGGF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHH
LLLSGRLGDLLGNKRVFLGGVVSFTVASVACGLAPSSGLLVVGRAVQGLGGAAVSAVALS
HHCCCCHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCHHHHHHHHHH
LIMGLFSDPAERARAMGFFGFVMSGGGAVGVLLGGVLTGLFSWHWIFLVNVPIGVGVWLA
HHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHH
ARRVLPADEVVPGAGRLDVPGAVLVTAALMLSVYGIVGGNEAGWTSGRTLGLLGASAVLL
HHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
AAFVLREARAASPLVPLRLFALRNVSVSQVVGMLWAAAMFAWFFLAALYLQQVLGYDALE
HHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VGLAFVPTSVVMAFCSLRVSDRLVMRFGIRRPLMAGLALAAASLALFSRAPVDGSFGTDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LPSMLLLGAGAGIAFNPVLLAAMGDVEPHESGLASGVVNTSFMMGGALGLAVLVSLSTWR
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TESLAADGADRLEALNGGFQFAFATGALAALAAAVIGGLLLRPKPMGGAELDAVAIADEP
CHHHHCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCC
TLDASLG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8440253 [H]