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The map label for this gene is rocA [H]

Identifier: 119718712

GI number: 119718712

Start: 4750871

End: 4752544

Strand: Reverse

Name: rocA [H]

Synonym: Noca_4493

Alternate gene names: 119718712

Gene position: 4752544-4750871 (Counterclockwise)

Preceding gene: 119718715

Following gene: 119718711

Centisome position: 95.32

GC content: 73.89

Gene sequence:

>1674_bases
ATGACCGAGACGACCGCGGGAGCCCTCTTCGACCGGCACCGGGCCCGGCTGGACGCCGCCGTCGCCGCCTGCGCGAGCCG
GGAGTACTACTCGGCGTTCGACGAGTCGCCGTCGCCGCGCGTGTACGGCGAGACCGCGGCCGCCGAGGGCAAGGCCGCGT
TCGAGGCCTGGCTCGGCTCGCCGTTCCCGCTCCCGACCCCGGGTGCCCAGGGCAGCGTCGCGACCGAGCGCTCGCCGTAC
GGCGTGGACCTCGGCGTCTCCTACCCGCGAGCGGTCGACGTCGACGCGCTGCTCTCGGCGGCGCGGGCCGGCATGAAGGG
GTGGCGCGACGCGGGCCCGGACGGACGGACCGGGGTGTGCCTGGAGATCCTGGCCCGGCTGCACGCGCGCATCTTCGAGC
TCGCCAACGCGGTGCAGCACACCAGCGGGCAGGCGTTCGTGATGGCGTTCCAGGCCGGCGGGGCGCACGCGCTCGACCGC
GCCCTGGAGGCGATCGCCTATGCGTGGACCGAGATGACCCGCACCCCGGCCACCGCCATCTGGGAGAAGCCCGGCCGCGG
TGGGCCGCTGCGGATGGAGAAGACGTTCACCGTGGTGCCCCGCGGGGTCGCGCTGGTGATCGGCTGCAACACCTTCCCCA
CCTGGAACTCCTGGCCGGGGCTGTTCGCGTCGCTGGTCACCGGCAACCCGGTCGTGGTCAAGCCACACCCGGCGGCCGTG
CTGCCGCTCGCGATCAGCGTCCAGGTGTGCCGCGAGGTGCTGGCCGAGGCCGGCTTCGACCCCGACCTCGTCCTCCTCGC
CGCCGAGGAGCCCGAGGACCGCCTGGCCGCGACGCTCGCGGTCCGCCCCGAGGTGCGGCTGATCGACTTCACCGGCGGGA
ACGCCTTCGGCGACTGGCTCGAGGCCAACGCGGGCCAGGCCGTCGTCTTCACCGAGAAGGCCGGCGTCAACACGGTGGTC
GTCGACTCGACCTCCGACTTCGCGGCGATGTGCCAGAACCTTGCGTTCTCGTTCGCGCTCTACTCCGGCCAGATGTGCAC
CGCCCCGCAGAACGTCTACGTGCCGGCCGCCGGGATCGCGACCGAGGACGGCGTGCGCTCGCCCGCCGAGGTGGGCGCCG
GGATCGGCGCGGCCCTCCAGGGGCTGCTCGGGGACGACGCGCGCGCGGTCGAGCTGCTCGGCGGCATCGTCAACGACGGG
GTGCTGGCCCGCCTGGAGAAGGCCGGCCGCGGCCACGTCCTCGTGCCGTCCCGCGAGGTCGCGCACCCGGCGTACGCCGA
CGCGACCGTCCGCACCCCCATGCTCGTCGGGCTCACCGCGGAGGACTCCGACGTGTACGAGTCCGAGTGCTTCGGGCCGG
TCGCCTACCTGATCGAGACCGAGGGCACCGACCAGTCGATCGACCTGTTCCGGCACACCGTGCTGGCCCACGGCGCGATG
ACCGCCGCGGTGTACTCCACCTCTCCCGAGGTCGTCGAGCAGGTGCGCGAGGCCGCCCTCGAGGCGGGGGTCGCCCTGTC
GGAGAACCTCCTGGGCGGGGTGTTCGTCAACCAGTCCGCGGCGTACTCCGACTTCCACGGCACCGGCGCCAACCCCGCCG
CGAACGCGGCGTACACCGACGGCGCCTACGTCGCCTCGCGGTTCCGCGTCGTGCAGTCCCGCCGCCACGTCTGA

Upstream 100 bases:

>100_bases
ATCTGTGCGACAGTGGCCGCGGCGTGTCACAGATCACGCCCGGCCCGGCCGCCGCCACCCACCGGCGGCCACCGCCACCC
CAGAGATCCAGGAGCGCCGC

Downstream 100 bases:

>100_bases
TGCGATGAGAACAACGTTCCCGCCCGGTCTGTCGATCTCGTAGTGCCCCGTTCGTGGAGAGGGTGACCCCCTTCCACCGA
GGAGACCGAGATGACCGACC

Product: phenylacetic acid degradation protein paaN

Products: NA

Alternate protein names: P5C dehydrogenase [H]

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MTETTAGALFDRHRARLDAAVAACASREYYSAFDESPSPRVYGETAAAEGKAAFEAWLGSPFPLPTPGAQGSVATERSPY
GVDLGVSYPRAVDVDALLSAARAGMKGWRDAGPDGRTGVCLEILARLHARIFELANAVQHTSGQAFVMAFQAGGAHALDR
ALEAIAYAWTEMTRTPATAIWEKPGRGGPLRMEKTFTVVPRGVALVIGCNTFPTWNSWPGLFASLVTGNPVVVKPHPAAV
LPLAISVQVCREVLAEAGFDPDLVLLAAEEPEDRLAATLAVRPEVRLIDFTGGNAFGDWLEANAGQAVVFTEKAGVNTVV
VDSTSDFAAMCQNLAFSFALYSGQMCTAPQNVYVPAAGIATEDGVRSPAEVGAGIGAALQGLLGDDARAVELLGGIVNDG
VLARLEKAGRGHVLVPSREVAHPAYADATVRTPMLVGLTAEDSDVYESECFGPVAYLIETEGTDQSIDLFRHTVLAHGAM
TAAVYSTSPEVVEQVREAALEAGVALSENLLGGVFVNQSAAYSDFHGTGANPAANAAYTDGAYVASRFRVVQSRRHV

Sequences:

>Translated_557_residues
MTETTAGALFDRHRARLDAAVAACASREYYSAFDESPSPRVYGETAAAEGKAAFEAWLGSPFPLPTPGAQGSVATERSPY
GVDLGVSYPRAVDVDALLSAARAGMKGWRDAGPDGRTGVCLEILARLHARIFELANAVQHTSGQAFVMAFQAGGAHALDR
ALEAIAYAWTEMTRTPATAIWEKPGRGGPLRMEKTFTVVPRGVALVIGCNTFPTWNSWPGLFASLVTGNPVVVKPHPAAV
LPLAISVQVCREVLAEAGFDPDLVLLAAEEPEDRLAATLAVRPEVRLIDFTGGNAFGDWLEANAGQAVVFTEKAGVNTVV
VDSTSDFAAMCQNLAFSFALYSGQMCTAPQNVYVPAAGIATEDGVRSPAEVGAGIGAALQGLLGDDARAVELLGGIVNDG
VLARLEKAGRGHVLVPSREVAHPAYADATVRTPMLVGLTAEDSDVYESECFGPVAYLIETEGTDQSIDLFRHTVLAHGAM
TAAVYSTSPEVVEQVREAALEAGVALSENLLGGVFVNQSAAYSDFHGTGANPAANAAYTDGAYVASRFRVVQSRRHV
>Mature_556_residues
TETTAGALFDRHRARLDAAVAACASREYYSAFDESPSPRVYGETAAAEGKAAFEAWLGSPFPLPTPGAQGSVATERSPYG
VDLGVSYPRAVDVDALLSAARAGMKGWRDAGPDGRTGVCLEILARLHARIFELANAVQHTSGQAFVMAFQAGGAHALDRA
LEAIAYAWTEMTRTPATAIWEKPGRGGPLRMEKTFTVVPRGVALVIGCNTFPTWNSWPGLFASLVTGNPVVVKPHPAAVL
PLAISVQVCREVLAEAGFDPDLVLLAAEEPEDRLAATLAVRPEVRLIDFTGGNAFGDWLEANAGQAVVFTEKAGVNTVVV
DSTSDFAAMCQNLAFSFALYSGQMCTAPQNVYVPAAGIATEDGVRSPAEVGAGIGAALQGLLGDDARAVELLGGIVNDGV
LARLEKAGRGHVLVPSREVAHPAYADATVRTPMLVGLTAEDSDVYESECFGPVAYLIETEGTDQSIDLFRHTVLAHGAMT
AAVYSTSPEVVEQVREAALEAGVALSENLLGGVFVNQSAAYSDFHGTGANPAANAAYTDGAYVASRFRVVQSRRHV

Specific function: Oxidizes Proline To Glutamate For Use As A Carbon And Nitrogen Source And Also Function As A Transcriptional Repressor Of The Put Operon. [C]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. RocA subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321828, Length=409, Percent_Identity=24.4498777506112, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005932 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.5.1.12 [H]

Molecular weight: Translated: 58452; Mature: 58321

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETTAGALFDRHRARLDAAVAACASREYYSAFDESPSPRVYGETAAAEGKAAFEAWLGS
CCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHCCC
PFPLPTPGAQGSVATERSPYGVDLGVSYPRAVDVDALLSAARAGMKGWRDAGPDGRTGVC
CCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHH
LEILARLHARIFELANAVQHTSGQAFVMAFQAGGAHALDRALEAIAYAWTEMTRTPATAI
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHH
WEKPGRGGPLRMEKTFTVVPRGVALVIGCNTFPTWNSWPGLFASLVTGNPVVVKPHPAAV
HCCCCCCCCEEEECEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEEECCCCCEE
LPLAISVQVCREVLAEAGFDPDLVLLAAEEPEDRLAATLAVRPEVRLIDFTGGNAFGDWL
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHEEEEEECCCEEEEEECCCCCHHHHH
EANAGQAVVFTEKAGVNTVVVDSTSDFAAMCQNLAFSFALYSGQMCTAPQNVYVPAAGIA
HCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEECCCCCEEECCCCCC
TEDGVRSPAEVGAGIGAALQGLLGDDARAVELLGGIVNDGVLARLEKAGRGHVLVPSREV
CCCCCCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCHHH
AHPAYADATVRTPMLVGLTAEDSDVYESECFGPVAYLIETEGTDQSIDLFRHTVLAHGAM
CCCCCCCCEECCCEEEEEECCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
TAAVYSTSPEVVEQVREAALEAGVALSENLLGGVFVNQSAAYSDFHGTGANPAANAAYTD
HEEEECCCHHHHHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCC
GAYVASRFRVVQSRRHV
CHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TETTAGALFDRHRARLDAAVAACASREYYSAFDESPSPRVYGETAAAEGKAAFEAWLGS
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHCCC
PFPLPTPGAQGSVATERSPYGVDLGVSYPRAVDVDALLSAARAGMKGWRDAGPDGRTGVC
CCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHH
LEILARLHARIFELANAVQHTSGQAFVMAFQAGGAHALDRALEAIAYAWTEMTRTPATAI
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHH
WEKPGRGGPLRMEKTFTVVPRGVALVIGCNTFPTWNSWPGLFASLVTGNPVVVKPHPAAV
HCCCCCCCCEEEECEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEEECCCCCEE
LPLAISVQVCREVLAEAGFDPDLVLLAAEEPEDRLAATLAVRPEVRLIDFTGGNAFGDWL
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHEEEEEECCCEEEEEECCCCCHHHHH
EANAGQAVVFTEKAGVNTVVVDSTSDFAAMCQNLAFSFALYSGQMCTAPQNVYVPAAGIA
HCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEECCCCCEEECCCCCC
TEDGVRSPAEVGAGIGAALQGLLGDDARAVELLGGIVNDGVLARLEKAGRGHVLVPSREV
CCCCCCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCHHH
AHPAYADATVRTPMLVGLTAEDSDVYESECFGPVAYLIETEGTDQSIDLFRHTVLAHGAM
CCCCCCCCEECCCEEEEEECCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
TAAVYSTSPEVVEQVREAALEAGVALSENLLGGVFVNQSAAYSDFHGTGANPAANAAYTD
HEEEECCCHHHHHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCC
GAYVASRFRVVQSRRHV
CHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA