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The map label for this gene is hycD [H]

Identifier: 119718687

GI number: 119718687

Start: 4722267

End: 4723217

Strand: Reverse

Name: hycD [H]

Synonym: Noca_4468

Alternate gene names: 119718687

Gene position: 4723217-4722267 (Counterclockwise)

Preceding gene: 119718688

Following gene: 119718686

Centisome position: 94.73

GC content: 72.77

Gene sequence:

>951_bases
GTGAGCGCCGGCGCGGTCGTGGTGACGGTGGTCCAGGCGGCGGTCCTGGTGGCGCTGTCCCCGCTGCTGGTGGGCGTGAT
GCGACAGGTGCGGGCCCGCCTCGAGGGGCGCGCCGGCGCGGGGGTCCTGCAGCCGTGGCGTGACCTGCGCAAGCTGCTGG
GCAAGGAGCCGTTGACGGCCGACGGCGTGAGCTGGATCTCGGCGGCCGGTCCGCTGGTGCTGGTCGCGTCCAGCCTGCTG
CTGTGTGCGCTGACGCCCGTGCTCGGGACGGCGACGCTCGACCGGGTGCCCAACGACCTGTTCGTCGTGGTCGCCGCGCT
GCTGATCGGGAGCGTCGCGCTCGCCCTGGTCGGCCTGGACGCCGGGACGGCCTTCGGCGGCATGGGGTCCAGCAGGCACA
TGATGATCGCGGCGCTGGTGGAGCCGACCGTCCTGGTCTCGGTGTACGCGCTGTCGATCCCGGTCGGCTCGTCGGTGTTG
TCCCACATCGTCGAGGCACGTCTCGACCATCCGGCGACCATCTGGTCGCCGGTCAGCCTGCTGGCGTTGCTGGGGCTCGC
GATCGCGATCGTGGCCGAGACCGCGCGGCTGCCGATCGACAACCCCTCCACCCACCTCGAGCTGACGATGGTCCACGAGG
CGATGGTCCTGGAGAGCTCGGGTCGCGACCTGGCCTGGCTGGAGCTCGGCTCGTGGCTGCGCCTGGGGGCCCTGCTCGGG
TTGCTCGCCACCCTCCTGGCGCCCTGGGGGGTCGCGACCGAGGTCACGGCCCTCGGCCTGGTCGTGGCCGTCGGTGCGCT
GGTCCTCAAGCTGGCGCTGATCGGCGCGCTGCTGGCGGCCGTCGAGGTGTTCCTGGCCAAGGTGCGGCTGTTCCGGGTGC
CCGAGCTGCTTGCCGGCTCCTTCGTGCTCGCCCTCCTCGCGGTGACCGCGTCCTACCTGGTGGCGAGCTGA

Upstream 100 bases:

>100_bases
GTGTCGGGGCCGCGGCGCGCCGGCTGCAGAACGGCAGCATCCATCGCTACCTGGGCTACTCCTTCGCCGCCCTGGTCGCC
GTGCTCGTGGTGGTCGCGCT

Downstream 100 bases:

>100_bases
TGGCCGCGGAGACGTTCGCGCAGCTGGTCGGTCTCAGCACCGGGGTCCTGCTGCTGTCCGCCGTCCTCCTGGTGTGGAGG
CGCTCCCTGCACGCCCAGGT

Product: putative formate hydrogenlyase HycD (FHL)

Products: NA

Alternate protein names: FHL subunit 4; Hydrogenase 3 component D [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSAGAVVVTVVQAAVLVALSPLLVGVMRQVRARLEGRAGAGVLQPWRDLRKLLGKEPLTADGVSWISAAGPLVLVASSLL
LCALTPVLGTATLDRVPNDLFVVVAALLIGSVALALVGLDAGTAFGGMGSSRHMMIAALVEPTVLVSVYALSIPVGSSVL
SHIVEARLDHPATIWSPVSLLALLGLAIAIVAETARLPIDNPSTHLELTMVHEAMVLESSGRDLAWLELGSWLRLGALLG
LLATLLAPWGVATEVTALGLVVAVGALVLKLALIGALLAAVEVFLAKVRLFRVPELLAGSFVLALLAVTASYLVAS

Sequences:

>Translated_316_residues
MSAGAVVVTVVQAAVLVALSPLLVGVMRQVRARLEGRAGAGVLQPWRDLRKLLGKEPLTADGVSWISAAGPLVLVASSLL
LCALTPVLGTATLDRVPNDLFVVVAALLIGSVALALVGLDAGTAFGGMGSSRHMMIAALVEPTVLVSVYALSIPVGSSVL
SHIVEARLDHPATIWSPVSLLALLGLAIAIVAETARLPIDNPSTHLELTMVHEAMVLESSGRDLAWLELGSWLRLGALLG
LLATLLAPWGVATEVTALGLVVAVGALVLKLALIGALLAAVEVFLAKVRLFRVPELLAGSFVLALLAVTASYLVAS
>Mature_315_residues
SAGAVVVTVVQAAVLVALSPLLVGVMRQVRARLEGRAGAGVLQPWRDLRKLLGKEPLTADGVSWISAAGPLVLVASSLLL
CALTPVLGTATLDRVPNDLFVVVAALLIGSVALALVGLDAGTAFGGMGSSRHMMIAALVEPTVLVSVYALSIPVGSSVLS
HIVEARLDHPATIWSPVSLLALLGLAIAIVAETARLPIDNPSTHLELTMVHEAMVLESSGRDLAWLELGSWLRLGALLGL
LATLLAPWGVATEVTALGLVVAVGALVLKLALIGALLAAVEVFLAKVRLFRVPELLAGSFVLALLAVTASYLVAS

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1789077, Length=306, Percent_Identity=31.6993464052288, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87082115, Length=254, Percent_Identity=30.7086614173228, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: NA

Molecular weight: Translated: 32480; Mature: 32349

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGAVVVTVVQAAVLVALSPLLVGVMRQVRARLEGRAGAGVLQPWRDLRKLLGKEPLTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
DGVSWISAAGPLVLVASSLLLCALTPVLGTATLDRVPNDLFVVVAALLIGSVALALVGLD
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
AGTAFGGMGSSRHMMIAALVEPTVLVSVYALSIPVGSSVLSHIVEARLDHPATIWSPVSL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHH
LALLGLAIAIVAETARLPIDNPSTHLELTMVHEAMVLESSGRDLAWLELGSWLRLGALLG
HHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
LLATLLAPWGVATEVTALGLVVAVGALVLKLALIGALLAAVEVFLAKVRLFRVPELLAGS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLALLAVTASYLVAS
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAGAVVVTVVQAAVLVALSPLLVGVMRQVRARLEGRAGAGVLQPWRDLRKLLGKEPLTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
DGVSWISAAGPLVLVASSLLLCALTPVLGTATLDRVPNDLFVVVAALLIGSVALALVGLD
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
AGTAFGGMGSSRHMMIAALVEPTVLVSVYALSIPVGSSVLSHIVEARLDHPATIWSPVSL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHH
LALLGLAIAIVAETARLPIDNPSTHLELTMVHEAMVLESSGRDLAWLELGSWLRLGALLG
HHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
LLATLLAPWGVATEVTALGLVVAVGALVLKLALIGALLAAVEVFLAKVRLFRVPELLAGS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLALLAVTASYLVAS
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2187144; 9278503 [H]