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The map label for this gene is hutI

Identifier: 119718604

GI number: 119718604

Start: 4636438

End: 4637613

Strand: Reverse

Name: hutI

Synonym: Noca_4385

Alternate gene names: 119718604

Gene position: 4637613-4636438 (Counterclockwise)

Preceding gene: 119718605

Following gene: 119718602

Centisome position: 93.02

GC content: 75.17

Gene sequence:

>1176_bases
GTGGCAAGCACCCTGATCACGAACATCGGCGAGCTCGTCACCAACGACCCCGAGGCCGCCGACGACGGCCGGGGGCTGCT
CGGGATCGTCGAGCAGGCCGCGCTCGTGATCGACGGCTCGACGGTCGCCTGGGTGGGCCGCGCCGCCGACGCCCCGGACG
CCGACCAGCTCGTCGACGCCGGCGGCCGGGCGGTGCTGCCCGGCTTCGTGGACAGTCACAGTCATCTGGTCTTCGCCGGC
GACCGGGCCGCGGAGTTCGCGGCGCGGATGGCCGGGACGCCGTACGCCGCCGGCGGCATCCGCACGACGGTGGCCGCCAC
CCGGGCCGCCACCGACGAGCAGCTCACCAGCCACGTCGCCCGGCTGGTCGAGGAGATGCGCCGCCAGGGCACGACCACGG
TCGAGATCAAGAGCGGCTACGGGCTGACCGTCCACGACGAGGCCCGCAGCCTCGCGGTCGCGCGGCAGTTCACCGAGGAG
ACGACGTTCCTCGGGGCGCACGTCGTGCCCGACGGCGACCCGGGGGAGTACGTCGACCTGGTCACCGGCCCGATGCTCGA
CGCGGCCCGGGAGCACGCCCGCTGGATCGACGTGTTCTGTGAGCGCGGCGCCTTCGACGCCGACCAGGCCCGGGCGATCC
TGGACGCCGGCGCGGCGGCCGGACTGCGCGGCCGGCTGCACGCCAACCAGCTGACCTACGGAGAGGGCGTCCGGCTCGCC
GCCGAGCTCGGCCTGGTCGCGGTCGACCACTGCACCTACCTGGCCGACGAGGACGTCGCCGCGCTGCGCGACAGCGGCAC
CATCGCCACGCTGCTGCCCGGGGTCGAGTTTTCGACCCGGCAGCCCTATCCCGACGCCCGCCGCCTCCTCGACGCGGGCG
TCCGGGTGGCTCTGGCCAGCGACTGCAACCCCGGGTCCTGCTTCACCAGCTCGATCCCGCTGTGCATCGCGCTCGCCGTC
CGTGAGATGGGGATGACCCCCGCGGAGGCGGTGCACGCGGCGACCTACCGCGGTGCCCAGGCCCTGGACCGCGACGGGCA
GCACGGGATCGGCGCGCTCGTGCCCGGGCGCCGCGCCGACCTCGCGGTGCTCGACGCCCCCTCCCACGTCCACCTCGCCT
ACCGCCCCGGCGTCCCTCTCGTCCGCCAGACCTGGGTCGCCGGCCGTCCGCTGTAA

Upstream 100 bases:

>100_bases
CCGCCGACGTCACCCACGTCGTCGTCGACGGCCGGGTCGTCGCGTCCGAGGACGACCACGAGGACATCGGCCGCGAGCTG
GCGGCTGCGATGGAGGCACT

Downstream 100 bases:

>100_bases
TACGACGAGGACGCGGCCGCTCAGGATCCGGCGACCACCTCGTGGATGTGGTCCGCGACCAGCCCGTGCGCCTCGCGGTG
GACGGCGGCGGCTGCCTCCG

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MASTLITNIGELVTNDPEAADDGRGLLGIVEQAALVIDGSTVAWVGRAADAPDADQLVDAGGRAVLPGFVDSHSHLVFAG
DRAAEFAARMAGTPYAAGGIRTTVAATRAATDEQLTSHVARLVEEMRRQGTTTVEIKSGYGLTVHDEARSLAVARQFTEE
TTFLGAHVVPDGDPGEYVDLVTGPMLDAAREHARWIDVFCERGAFDADQARAILDAGAAAGLRGRLHANQLTYGEGVRLA
AELGLVAVDHCTYLADEDVAALRDSGTIATLLPGVEFSTRQPYPDARRLLDAGVRVALASDCNPGSCFTSSIPLCIALAV
REMGMTPAEAVHAATYRGAQALDRDGQHGIGALVPGRRADLAVLDAPSHVHLAYRPGVPLVRQTWVAGRPL

Sequences:

>Translated_391_residues
MASTLITNIGELVTNDPEAADDGRGLLGIVEQAALVIDGSTVAWVGRAADAPDADQLVDAGGRAVLPGFVDSHSHLVFAG
DRAAEFAARMAGTPYAAGGIRTTVAATRAATDEQLTSHVARLVEEMRRQGTTTVEIKSGYGLTVHDEARSLAVARQFTEE
TTFLGAHVVPDGDPGEYVDLVTGPMLDAAREHARWIDVFCERGAFDADQARAILDAGAAAGLRGRLHANQLTYGEGVRLA
AELGLVAVDHCTYLADEDVAALRDSGTIATLLPGVEFSTRQPYPDARRLLDAGVRVALASDCNPGSCFTSSIPLCIALAV
REMGMTPAEAVHAATYRGAQALDRDGQHGIGALVPGRRADLAVLDAPSHVHLAYRPGVPLVRQTWVAGRPL
>Mature_390_residues
ASTLITNIGELVTNDPEAADDGRGLLGIVEQAALVIDGSTVAWVGRAADAPDADQLVDAGGRAVLPGFVDSHSHLVFAGD
RAAEFAARMAGTPYAAGGIRTTVAATRAATDEQLTSHVARLVEEMRRQGTTTVEIKSGYGLTVHDEARSLAVARQFTEET
TFLGAHVVPDGDPGEYVDLVTGPMLDAAREHARWIDVFCERGAFDADQARAILDAGAAAGLRGRLHANQLTYGEGVRLAA
ELGLVAVDHCTYLADEDVAALRDSGTIATLLPGVEFSTRQPYPDARRLLDAGVRVALASDCNPGSCFTSSIPLCIALAVR
EMGMTPAEAVHAATYRGAQALDRDGQHGIGALVPGRRADLAVLDAPSHVHLAYRPGVPLVRQTWVAGRPL

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=378, Percent_Identity=37.5661375661376, Blast_Score=206, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17555004, Length=353, Percent_Identity=34.8441926345609, Blast_Score=204, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_NOCSJ (A1SPZ7)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_925569.1
- ProteinModelPortal:   A1SPZ7
- SMR:   A1SPZ7
- STRING:   A1SPZ7
- GeneID:   4596903
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_4385
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK14085
- BioCyc:   NSP35761:NOCA_4385-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 41039; Mature: 40907

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: BINDING 82-82 BINDING 95-95 BINDING 140-140 BINDING 167-167 BINDING 230-230

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTLITNIGELVTNDPEAADDGRGLLGIVEQAALVIDGSTVAWVGRAADAPDADQLVDA
CCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHCEEEEECCCEEEEEECCCCCCCHHHHHHC
GGRAVLPGFVDSHSHLVFAGDRAAEFAARMAGTPYAAGGIRTTVAATRAATDEQLTSHVA
CCCEECCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHH
RLVEEMRRQGTTTVEIKSGYGLTVHDEARSLAVARQFTEETTFLGAHVVPDGDPGEYVDL
HHHHHHHHCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEH
VTGPMLDAAREHARWIDVFCERGAFDADQARAILDAGAAAGLRGRLHANQLTYGEGVRLA
HCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEH
AELGLVAVDHCTYLADEDVAALRDSGTIATLLPGVEFSTRQPYPDARRLLDAGVRVALAS
HHHCEEEEHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCEEEEEC
DCNPGSCFTSSIPLCIALAVREMGMTPAEAVHAATYRGAQALDRDGQHGIGALVPGRRAD
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCCCCCEEECCCCCCC
LAVLDAPSHVHLAYRPGVPLVRQTWVAGRPL
EEEEECCCEEEEEECCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
ASTLITNIGELVTNDPEAADDGRGLLGIVEQAALVIDGSTVAWVGRAADAPDADQLVDA
CCHHHHHHHHHHCCCCCCCCCCCCHHHHHHCEEEEECCCEEEEEECCCCCCCHHHHHHC
GGRAVLPGFVDSHSHLVFAGDRAAEFAARMAGTPYAAGGIRTTVAATRAATDEQLTSHVA
CCCEECCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHH
RLVEEMRRQGTTTVEIKSGYGLTVHDEARSLAVARQFTEETTFLGAHVVPDGDPGEYVDL
HHHHHHHHCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEH
VTGPMLDAAREHARWIDVFCERGAFDADQARAILDAGAAAGLRGRLHANQLTYGEGVRLA
HCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEH
AELGLVAVDHCTYLADEDVAALRDSGTIATLLPGVEFSTRQPYPDARRLLDAGVRVALAS
HHHCEEEEHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCEEEEEC
DCNPGSCFTSSIPLCIALAVREMGMTPAEAVHAATYRGAQALDRDGQHGIGALVPGRRAD
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCCCCCEEECCCCCCC
LAVLDAPSHVHLAYRPGVPLVRQTWVAGRPL
EEEEECCCEEEEEECCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA