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The map label for this gene is caiA [C]

Identifier: 119718511

GI number: 119718511

Start: 4534250

End: 4535419

Strand: Reverse

Name: caiA [C]

Synonym: Noca_4292

Alternate gene names: 119718511

Gene position: 4535419-4534250 (Counterclockwise)

Preceding gene: 119718512

Following gene: 119718510

Centisome position: 90.97

GC content: 71.62

Gene sequence:

>1170_bases
ATGACCCAGACCCCGCTCGGCCTCTTCGACACCGACTCCCTCGTCGATGCCGAGACCCTGGCCATCCGCGACACCGTCCG
CCGGTTCGTCGACGACCGGGTCCGACCCGAGGTCGCCGACTGGTACGAGGCGGGCACCGTCCCGGCCCGCGAGCTGGCCA
AGGAGCTCGGCGCGCTCGGCGTCCTCGGCATGCACCTGGAGGGCTACGGCTGTGCCGGCACCACCGCGACGGCGTACGGC
CTGGCCTGCCTCGAGCTCGAGGCAGGCGACTCCGGCGTCCGCTCGCTGGTGTCCGTGCAGGGCTCACTGGCGATGTTCGC
GATCTGGAAGCACGGCAGCGAGGCGCAGAAGCAGGAGTGGCTGCCGCGAATGGCCGCGGGTGAGGCGATCGGCTGCTTCG
GCCTGACCGAGCCGGACTTCGGCTCGAACCCCGCCGGCATGCGGACCCGCGCCCGCCAGGAGCCCTCGGGCGACTGGGTC
CTCGACGGCACCAAGATGTGGATCACCAACGGCTCGGTCGCCGACGTCGCCGTCGTCTGGGCGCAGACCGAGGGTGGCAT
CCGCGGGTTCGTCGTCCCCACCGACACTCCCGGCTTCTCCGCCCCGGAGATCAAGAAGAAGATGTCGCTGCGCGCCTCGG
TGACCAGCGAGCTCGTCCTGGACGGCGTCCGGCTGCCCGCCGACGCGGTGCTGCCCGAGGTGAGCGGCCTGTCCGGCCCG
CTGTCCTGCCTGAACGAGGCCCGCTTCGGGATCGCCTTCGGGGCCGTTGGCGCGGCCAGGGACTGCTTGGAGACCGCGAT
CGCCTACACCCGTGAGCGGGAGATCTTCGACAAGCCGCTCGCGGCGTACCAGCTCTCCCAGGCCAAGCTTGCCGACATGA
CCCTCGAGCTCGGCAAGGCGATGCTGCTCGCCCTGCAGCTGGGCCGGCTCAAGGACGAGGGGCGGCTGCGCCCCGAGCAG
GTCAGCCTCGGCAAGCTCAACAACGTCCGCGAGGCGCTCGCCATCGCCCGCGAGAGCCGCACCCTGCTCGGCGCCGCCGG
CATCACGCTGGAGTACCCGGTCCTGCGGCACGCCAACAACCTGGAGTCCGTGCTCACCTACGAGGGCACCAGCGAGGTGC
ACCAGCTGGTGATCGGCCGCGCTCTCACCGGCGAGGCCGCCTTCCGCTGA

Upstream 100 bases:

>100_bases
CTCGGGTGATGACGCTGTACGAAGGCACCAGCCAGATCCAGAAGCTGCTCATCGGGCGCGCCGAGACCGGCGTCAGCGCC
TTCCTCTGAAAGGGACCGTC

Downstream 100 bases:

>100_bases
GCCGACGAGGAGTGCCCACTGCCGGGTCGTGTGCCTCAGGACGCGCCATAGCGCGTCCTGAGGCACACGACCCGACCGGG
GACGAGCAGTGGCCCCCGCC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; BCAD; SCAD [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTQTPLGLFDTDSLVDAETLAIRDTVRRFVDDRVRPEVADWYEAGTVPARELAKELGALGVLGMHLEGYGCAGTTATAYG
LACLELEAGDSGVRSLVSVQGSLAMFAIWKHGSEAQKQEWLPRMAAGEAIGCFGLTEPDFGSNPAGMRTRARQEPSGDWV
LDGTKMWITNGSVADVAVVWAQTEGGIRGFVVPTDTPGFSAPEIKKKMSLRASVTSELVLDGVRLPADAVLPEVSGLSGP
LSCLNEARFGIAFGAVGAARDCLETAIAYTREREIFDKPLAAYQLSQAKLADMTLELGKAMLLALQLGRLKDEGRLRPEQ
VSLGKLNNVREALAIARESRTLLGAAGITLEYPVLRHANNLESVLTYEGTSEVHQLVIGRALTGEAAFR

Sequences:

>Translated_389_residues
MTQTPLGLFDTDSLVDAETLAIRDTVRRFVDDRVRPEVADWYEAGTVPARELAKELGALGVLGMHLEGYGCAGTTATAYG
LACLELEAGDSGVRSLVSVQGSLAMFAIWKHGSEAQKQEWLPRMAAGEAIGCFGLTEPDFGSNPAGMRTRARQEPSGDWV
LDGTKMWITNGSVADVAVVWAQTEGGIRGFVVPTDTPGFSAPEIKKKMSLRASVTSELVLDGVRLPADAVLPEVSGLSGP
LSCLNEARFGIAFGAVGAARDCLETAIAYTREREIFDKPLAAYQLSQAKLADMTLELGKAMLLALQLGRLKDEGRLRPEQ
VSLGKLNNVREALAIARESRTLLGAAGITLEYPVLRHANNLESVLTYEGTSEVHQLVIGRALTGEAAFR
>Mature_388_residues
TQTPLGLFDTDSLVDAETLAIRDTVRRFVDDRVRPEVADWYEAGTVPARELAKELGALGVLGMHLEGYGCAGTTATAYGL
ACLELEAGDSGVRSLVSVQGSLAMFAIWKHGSEAQKQEWLPRMAAGEAIGCFGLTEPDFGSNPAGMRTRARQEPSGDWVL
DGTKMWITNGSVADVAVVWAQTEGGIRGFVVPTDTPGFSAPEIKKKMSLRASVTSELVLDGVRLPADAVLPEVSGLSGPL
SCLNEARFGIAFGAVGAARDCLETAIAYTREREIFDKPLAAYQLSQAKLADMTLELGKAMLLALQLGRLKDEGRLRPEQV
SLGKLNNVREALAIARESRTLLGAAGITLEYPVLRHANNLESVLTYEGTSEVHQLVIGRALTGEAAFR

Specific function: Has an optimum specificity for 4-carbon length fatty acyl-CoAs [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=388, Percent_Identity=51.0309278350515, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI7669494, Length=368, Percent_Identity=50.8152173913043, Blast_Score=341, Evalue=9e-94,
Organism=Homo sapiens, GI4557233, Length=363, Percent_Identity=37.465564738292, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI226958412, Length=398, Percent_Identity=29.1457286432161, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI226958414, Length=345, Percent_Identity=31.0144927536232, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=30.0531914893617, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI4501857, Length=371, Percent_Identity=30.4582210242588, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI76496475, Length=374, Percent_Identity=29.9465240641711, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI4557235, Length=374, Percent_Identity=29.9465240641711, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=30.1587301587302, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI4557231, Length=369, Percent_Identity=29.810298102981, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI187960098, Length=369, Percent_Identity=29.810298102981, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI7656849, Length=365, Percent_Identity=26.3013698630137, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI48976061, Length=287, Percent_Identity=24.7386759581882, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI211971008, Length=287, Percent_Identity=24.7386759581882, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI38505218, Length=282, Percent_Identity=24.113475177305, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786223, Length=344, Percent_Identity=22.9651162790698, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87081958, Length=351, Percent_Identity=25.0712250712251, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17534353, Length=382, Percent_Identity=45.0261780104712, Blast_Score=343, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17538396, Length=381, Percent_Identity=30.7086614173228, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17506239, Length=387, Percent_Identity=29.7157622739018, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=30.2702702702703, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17569725, Length=378, Percent_Identity=30.1587301587302, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17534899, Length=373, Percent_Identity=29.7587131367292, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=29.7157622739018, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71985184, Length=344, Percent_Identity=30.2325581395349, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=30.2919708029197, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17533517, Length=379, Percent_Identity=25.3298153034301, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71985192, Length=272, Percent_Identity=31.6176470588235, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=31.8965517241379, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17551932, Length=285, Percent_Identity=28.0701754385965, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17505929, Length=377, Percent_Identity=26.2599469496021, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI71982178, Length=261, Percent_Identity=28.3524904214559, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI19920834, Length=390, Percent_Identity=50.2564102564103, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI21356377, Length=373, Percent_Identity=31.0991957104558, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=33.3333333333333, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24660351, Length=377, Percent_Identity=30.7692307692308, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI21355753, Length=346, Percent_Identity=32.3699421965318, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24666513, Length=385, Percent_Identity=28.5714285714286, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI281363737, Length=383, Percent_Identity=28.4595300261097, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41634; Mature: 41503

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTPLGLFDTDSLVDAETLAIRDTVRRFVDDRVRPEVADWYEAGTVPARELAKELGALG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHCCCE
VLGMHLEGYGCAGTTATAYGLACLELEAGDSGVRSLVSVQGSLAMFAIWKHGSEAQKQEW
EEEEEECCCCCCCCCHHHHCEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHH
LPRMAAGEAIGCFGLTEPDFGSNPAGMRTRARQEPSGDWVLDGTKMWITNGSVADVAVVW
CHHHHCCCCEEECCCCCCCCCCCCCCCCHHHCCCCCCCEEECCEEEEEECCCEEEEEEEE
AQTEGGIRGFVVPTDTPGFSAPEIKKKMSLRASVTSELVLDGVRLPADAVLPEVSGLSGP
EECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHCCCCCH
LSCLNEARFGIAFGAVGAARDCLETAIAYTREREIFDKPLAAYQLSQAKLADMTLELGKA
HHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
MLLALQLGRLKDEGRLRPEQVSLGKLNNVREALAIARESRTLLGAAGITLEYPVLRHANN
HHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCCEEEECCCEEECHHHHCCCC
LESVLTYEGTSEVHQLVIGRALTGEAAFR
HHHHEEECCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQTPLGLFDTDSLVDAETLAIRDTVRRFVDDRVRPEVADWYEAGTVPARELAKELGALG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHCCCE
VLGMHLEGYGCAGTTATAYGLACLELEAGDSGVRSLVSVQGSLAMFAIWKHGSEAQKQEW
EEEEEECCCCCCCCCHHHHCEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHH
LPRMAAGEAIGCFGLTEPDFGSNPAGMRTRARQEPSGDWVLDGTKMWITNGSVADVAVVW
CHHHHCCCCEEECCCCCCCCCCCCCCCCHHHCCCCCCCEEECCEEEEEECCCEEEEEEEE
AQTEGGIRGFVVPTDTPGFSAPEIKKKMSLRASVTSELVLDGVRLPADAVLPEVSGLSGP
EECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHCCCCCH
LSCLNEARFGIAFGAVGAARDCLETAIAYTREREIFDKPLAAYQLSQAKLADMTLELGKA
HHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
MLLALQLGRLKDEGRLRPEQVSLGKLNNVREALAIARESRTLLGAAGITLEYPVLRHANN
HHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCCEEEECCCEEECHHHHCCCC
LESVLTYEGTSEVHQLVIGRALTGEAAFR
HHHHEEECCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8399220; 7857927 [H]