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The map label for this gene is hemY [H]

Identifier: 119717894

GI number: 119717894

Start: 3894320

End: 3895702

Strand: Reverse

Name: hemY [H]

Synonym: Noca_3672

Alternate gene names: 119717894

Gene position: 3895702-3894320 (Counterclockwise)

Preceding gene: 119717896

Following gene: 119717893

Centisome position: 78.13

GC content: 77.44

Gene sequence:

>1383_bases
GTGAGCAGGGTCGTCGTCATCGGCGCCGGGATCGCCGGCCTGACCGCGGCACGCGACCTCGCCGACGCCGGGCAGGACGT
GGTCGTACTGGAGTCCTCGCCCCGGGCCGGCGGCAAGCTCCGCCGTGACCAGGTCGCCGGCGTCACGGTCGACGTCGGCG
CCGAGGCCATGTTGAACCGCCGCCCCGAGGGTGTCGGCCTGGCGGCCCGCCTCGGGCTGCCTCTCGAGCATCCGACCGTC
GCCTCGTCCCGGATCTGGACCCGCGGGGAGCTGCGGCCGCTGCCGCGCTCGCTGATGGGCATCCCGCTGGACCTGCCCCA
GCTGGAGCAGTCGGGTGTGCTCTCGGCCGAGGGCCTGGCCCGGGTGCGTGCCGAGCCGACGCTGTGGCCGGAACGGTTCG
AACCGCCCGACGGCGACGTCTCGGTCGGCGACCTGGTCGACCGCCGGTTCGGGCCCGAGGTCACCGACCGACTGGTCGAG
CCGCTGCTCGGCGGGGTGTACGCCGGGCACGCGCGGCTGATCTCGGCGCGCGCGTCGGTGCCGCAGCTGCTCGACTACGC
GTCCCGCGGCTCGGTCCTCGAGCAGGCCGCCGCGATCCCGACGACCTACGACCGGCCGGTGTTCGCCGGGATCCCGGGTG
GGATGGGCCGGCTGCCCGAGGCGCTCGCCGACGGGCTGCCGGCCGCGGGTGCCGTCGTCCGCACCGGCGCCACGGTCCGC
GGGCTCGCCCGCACCCCCACCGGCTTCGCCCTCACCGTCGGCCCGACCACCGCCCCCGAGCTGGTCGAGGCCGACGCGGT
CGTCCTGGCCCTGCCCGCCGCACCGGCCGCCCGGCTGCTCGCCGACGTGGCGCCGGCCGCCGCCACCGAGCTGGCGGCCG
TCGAGTCGGCGTCGATGGTCGTGGTGACGTTCGCGTTCCGCGGCAGCGACGTACCCGCCCTCGCGGCGACGGACTCCTCG
GGCTTCCTCGTCCCGCCCGTGGACGGCCGCCGCGTCAAGGCCGCGACCTTCTCGTTCGCGAAGTGGGGCTGGGTCCGTGC
CGCAGGCGACGGGCTGCTCCTGCTGCGCACCTCGCTCGGTCGGCACCGCGAGGAGACGGCGCTGCAGGCGACCGACGAGG
AGCTCGTGGCCTGGTCGCTCGCCGACCTCGCCGAGGCCGTCGGGCCGCTCGCCGCGCCGGCCGACACCCACGTGCAGCGT
TGGGGCGGTGGCCTGCCGCAGTACGCCGTCGGCCACCTCGACCGGGTGTCCCGGATCCGGGCCGCGGTCGCCGCGGTGCC
GGGTCTCGCCGTCTGCGGGGCGGCGTACGACGGCGTGGGGATCCCGGCCGTGATCGGCTCCGCCCGTCGCGCCGCCGCGG
AGGTGCTCGCCCTGCGCCCGTGA

Upstream 100 bases:

>100_bases
GAGAGCGGGGACCAGGGTGCGGACCGGGGTGAGCCTCATACCGGCTGGGACGGCCGACCCGGCGGATCGGTTCCGGTCCG
CCCTCTGGGAGGATCGCGGC

Downstream 100 bases:

>100_bases
GGCGTGCGGCGGGCCGGTGAGCGCGACGTGTAGCGGCTGCACGCCGCCGGCCGGGCAGAGGCGATCATCAACGCGCGGGA
GGCCGGCTACGGCCGCGATC

Product: protoporphyrinogen oxidase

Products: NA

Alternate protein names: PPO [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSRVVVIGAGIAGLTAARDLADAGQDVVVLESSPRAGGKLRRDQVAGVTVDVGAEAMLNRRPEGVGLAARLGLPLEHPTV
ASSRIWTRGELRPLPRSLMGIPLDLPQLEQSGVLSAEGLARVRAEPTLWPERFEPPDGDVSVGDLVDRRFGPEVTDRLVE
PLLGGVYAGHARLISARASVPQLLDYASRGSVLEQAAAIPTTYDRPVFAGIPGGMGRLPEALADGLPAAGAVVRTGATVR
GLARTPTGFALTVGPTTAPELVEADAVVLALPAAPAARLLADVAPAAATELAAVESASMVVVTFAFRGSDVPALAATDSS
GFLVPPVDGRRVKAATFSFAKWGWVRAAGDGLLLLRTSLGRHREETALQATDEELVAWSLADLAEAVGPLAAPADTHVQR
WGGGLPQYAVGHLDRVSRIRAAVAAVPGLAVCGAAYDGVGIPAVIGSARRAAAEVLALRP

Sequences:

>Translated_460_residues
MSRVVVIGAGIAGLTAARDLADAGQDVVVLESSPRAGGKLRRDQVAGVTVDVGAEAMLNRRPEGVGLAARLGLPLEHPTV
ASSRIWTRGELRPLPRSLMGIPLDLPQLEQSGVLSAEGLARVRAEPTLWPERFEPPDGDVSVGDLVDRRFGPEVTDRLVE
PLLGGVYAGHARLISARASVPQLLDYASRGSVLEQAAAIPTTYDRPVFAGIPGGMGRLPEALADGLPAAGAVVRTGATVR
GLARTPTGFALTVGPTTAPELVEADAVVLALPAAPAARLLADVAPAAATELAAVESASMVVVTFAFRGSDVPALAATDSS
GFLVPPVDGRRVKAATFSFAKWGWVRAAGDGLLLLRTSLGRHREETALQATDEELVAWSLADLAEAVGPLAAPADTHVQR
WGGGLPQYAVGHLDRVSRIRAAVAAVPGLAVCGAAYDGVGIPAVIGSARRAAAEVLALRP
>Mature_459_residues
SRVVVIGAGIAGLTAARDLADAGQDVVVLESSPRAGGKLRRDQVAGVTVDVGAEAMLNRRPEGVGLAARLGLPLEHPTVA
SSRIWTRGELRPLPRSLMGIPLDLPQLEQSGVLSAEGLARVRAEPTLWPERFEPPDGDVSVGDLVDRRFGPEVTDRLVEP
LLGGVYAGHARLISARASVPQLLDYASRGSVLEQAAAIPTTYDRPVFAGIPGGMGRLPEALADGLPAAGAVVRTGATVRG
LARTPTGFALTVGPTTAPELVEADAVVLALPAAPAARLLADVAPAAATELAAVESASMVVVTFAFRGSDVPALAATDSSG
FLVPPVDGRRVKAATFSFAKWGWVRAAGDGLLLLRTSLGRHREETALQATDEELVAWSLADLAEAVGPLAAPADTHVQRW
GGGLPQYAVGHLDRVSRIRAAVAAVPGLAVCGAAYDGVGIPAVIGSARRAAAEVLALRP

Specific function: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX [H]

COG id: COG1232

COG function: function code H; Protoporphyrinogen oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protoporphyrinogen oxidase family [H]

Homologues:

Organism=Homo sapiens, GI170650615, Length=498, Percent_Identity=26.9076305220884, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI4506001, Length=498, Percent_Identity=26.9076305220884, Blast_Score=106, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24649745, Length=471, Percent_Identity=25.9023354564756, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR004572 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: =1.3.3.4 [H]

Molecular weight: Translated: 47331; Mature: 47199

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVVVIGAGIAGLTAARDLADAGQDVVVLESSPRAGGKLRRDQVAGVTVDVGAEAMLNR
CCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHCCEEEECCHHHHHHC
RPEGVGLAARLGLPLEHPTVASSRIWTRGELRPLPRSLMGIPLDLPQLEQSGVLSAEGLA
CCCCCCCCEECCCCCCCCCCCCCCCEECCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHH
RVRAEPTLWPERFEPPDGDVSVGDLVDRRFGPEVTDRLVEPLLGGVYAGHARLISARASV
HHCCCCCCCCCCCCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCH
PQLLDYASRGSVLEQAAAIPTTYDRPVFAGIPGGMGRLPEALADGLPAAGAVVRTGATVR
HHHHHHHHCCHHHHHHHCCCCCCCCCEEECCCCCHHCCHHHHHCCCCCCCHHEECCCHHC
GLARTPTGFALTVGPTTAPELVEADAVVLALPAAPAARLLADVAPAAATELAAVESASMV
CCCCCCCCEEEEECCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEE
VVTFAFRGSDVPALAATDSSGFLVPPVDGRRVKAATFSFAKWGWVRAAGDGLLLLRTSLG
EEEEEECCCCCCEEEEECCCCEEECCCCCCEEEEEEECHHHCCEEEECCCCEEEEEHHHC
RHREETALQATDEELVAWSLADLAEAVGPLAAPADTHVQRWGGGLPQYAVGHLDRVSRIR
CHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
AAVAAVPGLAVCGAAYDGVGIPAVIGSARRAAAEVLALRP
HHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRVVVIGAGIAGLTAARDLADAGQDVVVLESSPRAGGKLRRDQVAGVTVDVGAEAMLNR
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHCCEEEECCHHHHHHC
RPEGVGLAARLGLPLEHPTVASSRIWTRGELRPLPRSLMGIPLDLPQLEQSGVLSAEGLA
CCCCCCCCEECCCCCCCCCCCCCCCEECCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHH
RVRAEPTLWPERFEPPDGDVSVGDLVDRRFGPEVTDRLVEPLLGGVYAGHARLISARASV
HHCCCCCCCCCCCCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCH
PQLLDYASRGSVLEQAAAIPTTYDRPVFAGIPGGMGRLPEALADGLPAAGAVVRTGATVR
HHHHHHHHCCHHHHHHHCCCCCCCCCEEECCCCCHHCCHHHHHCCCCCCCHHEECCCHHC
GLARTPTGFALTVGPTTAPELVEADAVVLALPAAPAARLLADVAPAAATELAAVESASMV
CCCCCCCCEEEEECCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEE
VVTFAFRGSDVPALAATDSSGFLVPPVDGRRVKAATFSFAKWGWVRAAGDGLLLLRTSLG
EEEEEECCCCCCEEEEECCCCEEECCCCCCEEEEEEECHHHCCEEEECCCCEEEEEHHHC
RHREETALQATDEELVAWSLADLAEAVGPLAAPADTHVQRWGGGLPQYAVGHLDRVSRIR
CHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
AAVAAVPGLAVCGAAYDGVGIPAVIGSARRAAAEVLALRP
HHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]