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The map label for this gene is cobM [H]

Identifier: 119717630

GI number: 119717630

Start: 3610160

End: 3610933

Strand: Reverse

Name: cobM [H]

Synonym: Noca_3408

Alternate gene names: 119717630

Gene position: 3610933-3610160 (Counterclockwise)

Preceding gene: 119717631

Following gene: 119717629

Centisome position: 72.42

GC content: 72.48

Gene sequence:

>774_bases
GTGAGTGCTGCCGTCCACTTCGTCGGCGCCGGACCCGGCGCGGCCGACCTGCTGACCGTGCGCGCGACTCGCCTGCTGGC
GCAGGCGGACCTGGTGCTCTATCCCGGCACCTACCTCGATCCCGAGGTCCTGGCCCACGTCGGCCCGGGCGCAGAGCTCG
TCGACACCCAAGACCTCGACCTCGACACGATGGTCGCCCAAATGGTCCGTGCAGCCGGCGCGGGCCAGGCGGTGGTGCGG
CTGACGTCCGGCGATCCGTCGCTCTATTCCGCGCTGCACGAGCAGACCTGCCGGCTCGATGCTGCTGGTGTTGCCTGGTC
GGTGACGCCCGGGGTGCCGGCCTACGCCGCCGCTGCTGCGCTGGTCGGCAGCGAGCTGACGGTGCCGCTGGTGGCCCAGT
CGGTGGTGCTGACCCGCGCCCAGGCTCGCTCTACCGTGATGCCGGAGTCCGAGTCGCTGGCGGCGTTCGCCACGACTCGC
TCGACGCTCGTGCTGCATCTGGCGATCACGCGGGTGCGGCCGCTCATGGCCGAGCTCGAACCGGAGTACGGCGGCGACTG
CCCGGTGGCCGTCGTCTACCGCGCCAGCCAGCCCGCAGAACAGGTGCTGCGCGGCACGGTGGCAACCATCTCGGAGGTGG
TGGAGGCGGCAGGGCTGCGCCAGGCGGCCGTGATCCTGGTCGGCTGGGCACTGGCCGGCGAGGGCGGCGAGTCCTATCTC
TACGACGCGGCCCGCGACCGGACCTCGAAGCGACGCGACGATCGGGGGCTGTGA

Upstream 100 bases:

>100_bases
ACCTGGACCCGGAGACGATCGACATGAAGTGCCTGCTGATCGTGGGTGCCGAGAGGACACGGGTGAGCCGCGCCGGCGTG
TGGACGCCGAGGTACGTGCG

Downstream 100 bases:

>100_bases
TGGAGTTCTACGACGTCATCAACCGTCGTCGTGACACTCGCCGAGAGTTCACAGGTGAGCCGTTGGCCGCCGAGGTGCTG
GAGCGGCTGTTGTCGGCGGC

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSAAVHFVGAGPGAADLLTVRATRLLAQADLVLYPGTYLDPEVLAHVGPGAELVDTQDLDLDTMVAQMVRAAGAGQAVVR
LTSGDPSLYSALHEQTCRLDAAGVAWSVTPGVPAYAAAAALVGSELTVPLVAQSVVLTRAQARSTVMPESESLAAFATTR
STLVLHLAITRVRPLMAELEPEYGGDCPVAVVYRASQPAEQVLRGTVATISEVVEAAGLRQAAVILVGWALAGEGGESYL
YDAARDRTSKRRDDRGL

Sequences:

>Translated_257_residues
MSAAVHFVGAGPGAADLLTVRATRLLAQADLVLYPGTYLDPEVLAHVGPGAELVDTQDLDLDTMVAQMVRAAGAGQAVVR
LTSGDPSLYSALHEQTCRLDAAGVAWSVTPGVPAYAAAAALVGSELTVPLVAQSVVLTRAQARSTVMPESESLAAFATTR
STLVLHLAITRVRPLMAELEPEYGGDCPVAVVYRASQPAEQVLRGTVATISEVVEAAGLRQAAVILVGWALAGEGGESYL
YDAARDRTSKRRDDRGL
>Mature_256_residues
SAAVHFVGAGPGAADLLTVRATRLLAQADLVLYPGTYLDPEVLAHVGPGAELVDTQDLDLDTMVAQMVRAAGAGQAVVRL
TSGDPSLYSALHEQTCRLDAAGVAWSVTPGVPAYAAAAALVGSELTVPLVAQSVVLTRAQARSTVMPESESLAAFATTRS
TLVLHLAITRVRPLMAELEPEYGGDCPVAVVYRASQPAEQVLRGTVATISEVVEAAGLRQAAVILVGWALAGEGGESYLY
DAARDRTSKRRDDRGL

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=236, Percent_Identity=29.6610169491525, Blast_Score=82, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322922, Length=240, Percent_Identity=28.75, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 26747; Mature: 26616

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAVHFVGAGPGAADLLTVRATRLLAQADLVLYPGTYLDPEVLAHVGPGAELVDTQDLD
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCC
LDTMVAQMVRAAGAGQAVVRLTSGDPSLYSALHEQTCRLDAAGVAWSVTPGVPAYAAAAA
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
LVGSELTVPLVAQSVVLTRAQARSTVMPESESLAAFATTRSTLVLHLAITRVRPLMAELE
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEYGGDCPVAVVYRASQPAEQVLRGTVATISEVVEAAGLRQAAVILVGWALAGEGGESYL
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEEHCCCCCCHHH
YDAARDRTSKRRDDRGL
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SAAVHFVGAGPGAADLLTVRATRLLAQADLVLYPGTYLDPEVLAHVGPGAELVDTQDLD
CCEEEEEECCCCHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCC
LDTMVAQMVRAAGAGQAVVRLTSGDPSLYSALHEQTCRLDAAGVAWSVTPGVPAYAAAAA
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
LVGSELTVPLVAQSVVLTRAQARSTVMPESESLAAFATTRSTLVLHLAITRVRPLMAELE
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEYGGDCPVAVVYRASQPAEQVLRGTVATISEVVEAAGLRQAAVILVGWALAGEGGESYL
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEEHCCCCCCHHH
YDAARDRTSKRRDDRGL
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200543 [H]