BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is fabG [H]

Identifier: 119716966

GI number: 119716966

Start: 2914287

End: 2915168

Strand: Reverse

Name: fabG [H]

Synonym: Noca_2741

Alternate gene names: 119716966

Gene position: 2915168-2914287 (Counterclockwise)

Preceding gene: 119716967

Following gene: 119716964

Centisome position: 58.47

GC content: 74.04

Gene sequence:

>882_bases
ATGTCGTCATTGTTGGAAGGTCGGGTCGCGATCGTGACCGGCGCGGGCCGCGGCATCGGCCGCGCGCACGCACTCGAGCT
CGCCCGGCACGGCGCCGCCGTGGTCGTGAACGACTACGGCGTCTCGTTGGCGGGTGAGGAGTCCGGTGAGACCCCGGCCG
AGTCGGTCGTCGCCGAGATCGAGGCCGCCGGTGGCCGGGCGGTGGTCAACACCGCCGACGTCGCGGACTTCGACCAGGCC
GCGGCGATGGTCCAGCAGGCGGTCTCGACGTACGGCGGGCTCGACGTCTTGGTGAACAACGCCGGGTTCGTGCGCGACCG
GATGCTGGTGAACACGGCCGAGGAGGAGTGGGACGCGGTGATCCGGGTGCACCTCAAGGGGCACTTCGCGCCGCTGCGCC
ACGCCGGCGCCTACTGGCGGGCGGAGGCGAAGGCGGGGCGGCCGCGTGCGGCCCGGGTCATCAACACCTCGTCCGGAGCC
GGCCTCCAGGGCTCGGTCGGCCAGGCGACGTACTCCGCGGCCAAGGCGGGCATCGCCGGGCTCACCCTGGTCGCCGCCCA
GGAGCTCGGCAGGTACGGCGTGACCGTCAACGCGATCGCCCCGGTGGCGCGGACCCGGATGACCGAGGGCGCGTTCGACA
CCTCGGCGATGGCGATGCCCGAGGACAACTCGCCCATCGTCGCGTGGCTGGCGTCGGCCGACGCCGGCGACGTCACCGGG
CGGGTGATCGAGATCGACGGCTCGACCATCACCGTCGAGACCGGCTGGGCCCACGGCCCCAAGAACGACCTCGGCCGCAG
GTGGGAGGCGGCCGAGGTCGGCCCGGCGGTGCGTGCCCTTCTCGCCGCCGCGCCCGCCCCGGAGCCGGTGTACGGGGCGT
AG

Upstream 100 bases:

>100_bases
ACCTGGCGTCGTACGTGTCCGGGGCGAGCCTCGCCTGCCACGGCGGGGGAGAGCCACCCGCCTTCCTCGTCGTCTCGAAC
ATCGTCTCGAAGGGGCCGTG

Downstream 100 bases:

>100_bases
GCGCCGGTTTCACTGGCCAAGCCGCAACGCCGCCCGACCCCTCAGATCCGCTCGAGGACCGTCCCGGTCGCCATGGCCCC
ACCGGCACACATGGTGATCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSSLLEGRVAIVTGAGRGIGRAHALELARHGAAVVVNDYGVSLAGEESGETPAESVVAEIEAAGGRAVVNTADVADFDQA
AAMVQQAVSTYGGLDVLVNNAGFVRDRMLVNTAEEEWDAVIRVHLKGHFAPLRHAGAYWRAEAKAGRPRAARVINTSSGA
GLQGSVGQATYSAAKAGIAGLTLVAAQELGRYGVTVNAIAPVARTRMTEGAFDTSAMAMPEDNSPIVAWLASADAGDVTG
RVIEIDGSTITVETGWAHGPKNDLGRRWEAAEVGPAVRALLAAAPAPEPVYGA

Sequences:

>Translated_293_residues
MSSLLEGRVAIVTGAGRGIGRAHALELARHGAAVVVNDYGVSLAGEESGETPAESVVAEIEAAGGRAVVNTADVADFDQA
AAMVQQAVSTYGGLDVLVNNAGFVRDRMLVNTAEEEWDAVIRVHLKGHFAPLRHAGAYWRAEAKAGRPRAARVINTSSGA
GLQGSVGQATYSAAKAGIAGLTLVAAQELGRYGVTVNAIAPVARTRMTEGAFDTSAMAMPEDNSPIVAWLASADAGDVTG
RVIEIDGSTITVETGWAHGPKNDLGRRWEAAEVGPAVRALLAAAPAPEPVYGA
>Mature_292_residues
SSLLEGRVAIVTGAGRGIGRAHALELARHGAAVVVNDYGVSLAGEESGETPAESVVAEIEAAGGRAVVNTADVADFDQAA
AMVQQAVSTYGGLDVLVNNAGFVRDRMLVNTAEEEWDAVIRVHLKGHFAPLRHAGAYWRAEAKAGRPRAARVINTSSGAG
LQGSVGQATYSAAKAGIAGLTLVAAQELGRYGVTVNAIAPVARTRMTEGAFDTSAMAMPEDNSPIVAWLASADAGDVTGR
VIEIDGSTITVETGWAHGPKNDLGRRWEAAEVGPAVRALLAAAPAPEPVYGA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=268, Percent_Identity=38.8059701492537, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI15277342, Length=272, Percent_Identity=35.2941176470588, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI40254986, Length=222, Percent_Identity=29.2792792792793, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4758504, Length=236, Percent_Identity=33.0508474576271, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=33.6683417085427, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=26.8199233716475, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=29.0076335877863, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI83715985, Length=197, Percent_Identity=33.502538071066, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI224922801, Length=182, Percent_Identity=32.967032967033, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI66933014, Length=274, Percent_Identity=27.7372262773723, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40254992, Length=203, Percent_Identity=29.5566502463054, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI209862901, Length=280, Percent_Identity=25, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI19923983, Length=280, Percent_Identity=25, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI5031737, Length=261, Percent_Identity=26.8199233716475, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=260, Percent_Identity=33.4615384615385, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=30.7392996108949, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=30.1587301587302, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082100, Length=276, Percent_Identity=29.7101449275362, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=33.8582677165354, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87082160, Length=197, Percent_Identity=29.9492385786802, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790717, Length=263, Percent_Identity=30.0380228136882, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787526, Length=255, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=27.734375, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787905, Length=98, Percent_Identity=39.7959183673469, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786812, Length=197, Percent_Identity=28.4263959390863, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=246, Percent_Identity=38.2113821138211, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=33.976833976834, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=32.4324324324324, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71982365, Length=219, Percent_Identity=31.0502283105023, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=239, Percent_Identity=31.3807531380753, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=265, Percent_Identity=26.7924528301887, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=205, Percent_Identity=27.8048780487805, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17558628, Length=201, Percent_Identity=30.3482587064677, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=285, Percent_Identity=28.7719298245614, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=260, Percent_Identity=28.0769230769231, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=27.8625954198473, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=232, Percent_Identity=30.1724137931034, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=222, Percent_Identity=31.0810810810811, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=28, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=226, Percent_Identity=31.4159292035398, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=291, Percent_Identity=27.4914089347079, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=216, Percent_Identity=25.462962962963, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86565303, Length=223, Percent_Identity=28.2511210762332, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=216, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71997099, Length=253, Percent_Identity=26.4822134387352, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=208, Percent_Identity=29.3269230769231, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=25.4826254826255, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=289, Percent_Identity=26.643598615917, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=201, Percent_Identity=27.8606965174129, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=207, Percent_Identity=28.9855072463768, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=240, Percent_Identity=40, Blast_Score=164, Evalue=1e-41,
Organism=Drosophila melanogaster, GI18859837, Length=254, Percent_Identity=40.9448818897638, Blast_Score=170, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24639444, Length=267, Percent_Identity=33.7078651685393, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17737361, Length=225, Percent_Identity=30.2222222222222, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=31.8007662835249, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21357673, Length=201, Percent_Identity=30.8457711442786, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=26.6409266409266, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=27.7992277992278, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649181, Length=175, Percent_Identity=33.1428571428571, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21357041, Length=261, Percent_Identity=28.735632183908, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571526, Length=265, Percent_Identity=28.3018867924528, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640492, Length=243, Percent_Identity=24.6913580246914, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 30059; Mature: 29928

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLLEGRVAIVTGAGRGIGRAHALELARHGAAVVVNDYGVSLAGEESGETPAESVVAEI
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCEEECCCCCCCCHHHHHHHHH
EAAGGRAVVNTADVADFDQAAAMVQQAVSTYGGLDVLVNNAGFVRDRMLVNTAEEEWDAV
HCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCHHHHCEE
IRVHLKGHFAPLRHAGAYWRAEAKAGRPRAARVINTSSGAGLQGSVGQATYSAAKAGIAG
EEEEECCCCCHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCHHH
LTLVAAQELGRYGVTVNAIAPVARTRMTEGAFDTSAMAMPEDNSPIVAWLASADAGDVTG
HHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCC
RVIEIDGSTITVETGWAHGPKNDLGRRWEAAEVGPAVRALLAAAPAPEPVYGA
EEEEECCCEEEEECCCCCCCCHHHCCCCCHHHCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SSLLEGRVAIVTGAGRGIGRAHALELARHGAAVVVNDYGVSLAGEESGETPAESVVAEI
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCEEECCCCCCCCHHHHHHHHH
EAAGGRAVVNTADVADFDQAAAMVQQAVSTYGGLDVLVNNAGFVRDRMLVNTAEEEWDAV
HCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCHHHHCEE
IRVHLKGHFAPLRHAGAYWRAEAKAGRPRAARVINTSSGAGLQGSVGQATYSAAKAGIAG
EEEEECCCCCHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCHHH
LTLVAAQELGRYGVTVNAIAPVARTRMTEGAFDTSAMAMPEDNSPIVAWLASADAGDVTG
HHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCC
RVIEIDGSTITVETGWAHGPKNDLGRRWEAAEVGPAVRALLAAAPAPEPVYGA
EEEEECCCEEEEECCCCCCCCHHHCCCCCHHHCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]