BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is gdhII [H]

Identifier: 119716967

GI number: 119716967

Start: 2915168

End: 2915926

Strand: Reverse

Name: gdhII [H]

Synonym: Noca_2742

Alternate gene names: 119716967

Gene position: 2915926-2915168 (Counterclockwise)

Preceding gene: 119716972

Following gene: 119716966

Centisome position: 58.48

GC content: 73.52

Gene sequence:

>759_bases
GTGGACCTCACCGGACGCGTCGCGCTCGTCACGGGCGGGACGCGCGGCATCGGGCTCGGCATCACCCGGTCGCTGCTCGC
CGCCGGCGCCTCGGTCGTCACCTGCTCGCGCTCGGACGTCGAGCCGGTGCCGGGGACGACACACCGGGCCTGCGACGTGC
GCGACGCCGACGCGGTGCAGGCGCTCGTCGCGTCCGTGGCCGAGTCGCACGGCCGGCTCGACGTACTGGTCAACAACGCC
GGGGGAGCGCCCGCGAGCGACGCGGCGACCGCGTCGCCGCGGTTCCACGAGAAGATCGTCGGGCTCAACCTGCTCGCGCC
GCTGGTGTGCGCGCAGGCCGCGAACGCCGTGATGCAGCAGCAGGACGCGGGCGGGGTGATCGTCAACATCTCCTCGGTCT
CCGCGAACCGCCCGGCGCCGACGATCGCGGCGTACGGCGCGGCCAAGGCCGGCCTCGACTCGCTCACCGCCTCGCTCGCG
ATGGAGTGGGCGCCCAAGGTACGCGTGAACGCGATCGACGTGGGGCTGTGCCGGACCGAGCAGACCGGCGACCACTACGG
GGACGACGTCTCGGTAGCCGCGATCGAGCAGACGATCCCGCTCGGCCGGATGGCGGACCCGATCGAGGTCGGGAACGTCG
CGGCGTTCCTGGCCAGCGACCTGGCGTCGTACGTGTCCGGGGCGAGCCTCGCCTGCCACGGCGGGGGAGAGCCACCCGCC
TTCCTCGTCGTCTCGAACATCGTCTCGAAGGGGCCGTGA

Upstream 100 bases:

>100_bases
CATCGTCACCACCCGGATGCCGTCGTCGCGGAGGTCCGAAGTGATCGCCATGGCACCCAACCTAACACTTGCTTGGTATG
CTCGTCCCATGTCGCTGGCC

Downstream 100 bases:

>100_bases
TGTCGTCATTGTTGGAAGGTCGGGTCGCGATCGTGACCGGCGCGGGCCGCGGCATCGGCCGCGCGCACGCACTCGAGCTC
GCCCGGCACGGCGCCGCCGT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: GLCDH-II [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MDLTGRVALVTGGTRGIGLGITRSLLAAGASVVTCSRSDVEPVPGTTHRACDVRDADAVQALVASVAESHGRLDVLVNNA
GGAPASDAATASPRFHEKIVGLNLLAPLVCAQAANAVMQQQDAGGVIVNISSVSANRPAPTIAAYGAAKAGLDSLTASLA
MEWAPKVRVNAIDVGLCRTEQTGDHYGDDVSVAAIEQTIPLGRMADPIEVGNVAAFLASDLASYVSGASLACHGGGEPPA
FLVVSNIVSKGP

Sequences:

>Translated_252_residues
MDLTGRVALVTGGTRGIGLGITRSLLAAGASVVTCSRSDVEPVPGTTHRACDVRDADAVQALVASVAESHGRLDVLVNNA
GGAPASDAATASPRFHEKIVGLNLLAPLVCAQAANAVMQQQDAGGVIVNISSVSANRPAPTIAAYGAAKAGLDSLTASLA
MEWAPKVRVNAIDVGLCRTEQTGDHYGDDVSVAAIEQTIPLGRMADPIEVGNVAAFLASDLASYVSGASLACHGGGEPPA
FLVVSNIVSKGP
>Mature_252_residues
MDLTGRVALVTGGTRGIGLGITRSLLAAGASVVTCSRSDVEPVPGTTHRACDVRDADAVQALVASVAESHGRLDVLVNNA
GGAPASDAATASPRFHEKIVGLNLLAPLVCAQAANAVMQQQDAGGVIVNISSVSANRPAPTIAAYGAAKAGLDSLTASLA
MEWAPKVRVNAIDVGLCRTEQTGDHYGDDVSVAAIEQTIPLGRMADPIEVGNVAAFLASDLASYVSGASLACHGGGEPPA
FLVVSNIVSKGP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=32.258064516129, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI10190704, Length=263, Percent_Identity=32.6996197718631, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI7705925, Length=242, Percent_Identity=31.8181818181818, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=32.3144104803493, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=28.6852589641434, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=30.7053941908714, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=33.160621761658, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4503301, Length=196, Percent_Identity=30.1020408163265, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI31542939, Length=197, Percent_Identity=31.9796954314721, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI109715829, Length=208, Percent_Identity=28.3653846153846, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=32.6424870466321, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=29.7619047619048, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI224922801, Length=188, Percent_Identity=31.3829787234043, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=36.046511627907, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=32.3770491803279, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=31.9672131147541, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=31.8725099601594, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=34.0080971659919, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=29.2682926829268, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=29.2682926829268, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=29.3172690763052, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=29.5833333333333, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=27.3469387755102, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=28.8537549407115, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787545, Length=249, Percent_Identity=27.710843373494, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789057, Length=196, Percent_Identity=30.6122448979592, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=33.0645161290323, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=32.5301204819277, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=34.8360655737705, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=31.8181818181818, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=31.5589353612167, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=32.0610687022901, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=30.5220883534137, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17561272, Length=251, Percent_Identity=32.2709163346614, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=30.6513409961686, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=31.8367346938775, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=29.4339622641509, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=29.6153846153846, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=30.2325581395349, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=27.8195488721804, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=28.1124497991968, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=27.4809160305344, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=29.6153846153846, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28.8, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=28.1368821292776, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=27.9245283018868, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=278, Percent_Identity=28.0575539568345, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI86565303, Length=191, Percent_Identity=28.7958115183246, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=27.0676691729323, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=191, Percent_Identity=28.2722513089005, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=31.1023622047244, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=30.4, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=28.1124497991968, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=25.5102040816327, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=29.7959183673469, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=33.4677419354839, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=32.0987654320988, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=32.7935222672065, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=33.4677419354839, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=31.6205533596838, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=31.7269076305221, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644337, Length=192, Percent_Identity=32.8125, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI116007236, Length=195, Percent_Identity=31.2820512820513, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007234, Length=203, Percent_Identity=30.5418719211823, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24665243, Length=174, Percent_Identity=31.6091954022989, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI221331218, Length=174, Percent_Identity=31.6091954022989, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI116007238, Length=184, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221331216, Length=175, Percent_Identity=31.4285714285714, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24665247, Length=175, Percent_Identity=31.4285714285714, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007232, Length=185, Percent_Identity=30.2702702702703, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 25286; Mature: 25286

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTGRVALVTGGTRGIGLGITRSLLAAGASVVTCSRSDVEPVPGTTHRACDVRDADAVQ
CCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
ALVASVAESHGRLDVLVNNAGGAPASDAATASPRFHEKIVGLNLLAPLVCAQAANAVMQQ
HHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDAGGVIVNISSVSANRPAPTIAAYGAAKAGLDSLTASLAMEWAPKVRVNAIDVGLCRTE
CCCCCEEEEEECCCCCCCCCCEEHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCC
QTGDHYGDDVSVAAIEQTIPLGRMADPIEVGNVAAFLASDLASYVSGASLACHGGGEPPA
CCCCCCCCCEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHH
FLVVSNIVSKGP
HHHHHHHHHCCC
>Mature Secondary Structure
MDLTGRVALVTGGTRGIGLGITRSLLAAGASVVTCSRSDVEPVPGTTHRACDVRDADAVQ
CCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
ALVASVAESHGRLDVLVNNAGGAPASDAATASPRFHEKIVGLNLLAPLVCAQAANAVMQQ
HHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDAGGVIVNISSVSANRPAPTIAAYGAAKAGLDSLTASLAMEWAPKVRVNAIDVGLCRTE
CCCCCEEEEEECCCCCCCCCCEEHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCC
QTGDHYGDDVSVAAIEQTIPLGRMADPIEVGNVAAFLASDLASYVSGASLACHGGGEPPA
CCCCCCCCCEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHH
FLVVSNIVSKGP
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA