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The map label for this gene is yciL [C]

Identifier: 119716723

GI number: 119716723

Start: 2665992

End: 2666747

Strand: Direct

Name: yciL [C]

Synonym: Noca_2497

Alternate gene names: 119716723

Gene position: 2665992-2666747 (Clockwise)

Preceding gene: 119716722

Following gene: 119716724

Centisome position: 53.47

GC content: 70.63

Gene sequence:

>756_bases
GTGACCACCCCGGGCATCGAGTCCGACGACGACGGCCTGGTCCGGCTGCAGAAGCTGCTCGCCCAGTCCGGCGTCGCGTC
GCGGCGCAAGTGCGAGGAGCTGATGCTCGAGGGGCACGTCGTCGTCGACGGCGAGGTCGTCACCCGGCTCGGCACCAAGG
TCGACCCGCGGACCGCGGTGATCCGGGTCGACGGCAAGCGGCTGCCACCGGTGTCGGAGAAGGTCTACCTGGTGCTGAAC
AAGCCCCGCGGTGTGGTGTCCACGATGTCGGACCCGGAGGGACGGCGCACGCTGTCCGACCTCGTCGCCGATCGCCCGGA
GCGGCTCTTCCACGTCGGTCGTCTCGACACCGACACGTCGGGGCTGCTGCTCCTGACCAACGACGGCGACTTCGCGCACC
GGATGGCGCATCCCTCCTACGAGGTCGACAAGACCTACGTCGCAGAGGTCGAGGGCGAGGTCTACCGACGCACAATCAAG
CAGCTGCTCGAAGGGGTGACCCTCGACGACGGGCCGGTCACGGTCTCGAAGGCGCGGATCGTCGAGGCGACGGCGGCGAA
GTCGATCGTCGAGCTGGTCATCCACGAGGGCCGCAACCGGATCGTGCGCCGGCTGCTCGACCAGGTCGGGCACCCCGTGC
GTCGCCTCACCCGCACCGCGATCGGGCCGGTCTCCCTCGGCCGGCTGCCCAGCGGGGAGCTGCGGGACCTGACCCGCCAG
GAGCTCGGCGAGCTGCTGGACACCGCCCAGCTGTAG

Upstream 100 bases:

>100_bases
CCGCCACCGAGGCGGCGCCCGAGCCGGAGCCGCAGCCGGGGCACCCCCACTCCCCGCACAGCGGCGACGGGACCGAGCCC
GACGGGGGGACCGAGCCCAC

Downstream 100 bases:

>100_bases
GCGCCCCCGAAGGCTTCGCCGGTTCGGCTCCGGGCCGGTGCCGCGGTCGCTAGCGTCGTCGTATGAGCGTGGCCACCGAC
CTCTCCTATCAGCCGAGACC

Product: ribosomal large subunit pseudouridine synthase B

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTTPGIESDDDGLVRLQKLLAQSGVASRRKCEELMLEGHVVVDGEVVTRLGTKVDPRTAVIRVDGKRLPPVSEKVYLVLN
KPRGVVSTMSDPEGRRTLSDLVADRPERLFHVGRLDTDTSGLLLLTNDGDFAHRMAHPSYEVDKTYVAEVEGEVYRRTIK
QLLEGVTLDDGPVTVSKARIVEATAAKSIVELVIHEGRNRIVRRLLDQVGHPVRRLTRTAIGPVSLGRLPSGELRDLTRQ
ELGELLDTAQL

Sequences:

>Translated_251_residues
MTTPGIESDDDGLVRLQKLLAQSGVASRRKCEELMLEGHVVVDGEVVTRLGTKVDPRTAVIRVDGKRLPPVSEKVYLVLN
KPRGVVSTMSDPEGRRTLSDLVADRPERLFHVGRLDTDTSGLLLLTNDGDFAHRMAHPSYEVDKTYVAEVEGEVYRRTIK
QLLEGVTLDDGPVTVSKARIVEATAAKSIVELVIHEGRNRIVRRLLDQVGHPVRRLTRTAIGPVSLGRLPSGELRDLTRQ
ELGELLDTAQL
>Mature_250_residues
TTPGIESDDDGLVRLQKLLAQSGVASRRKCEELMLEGHVVVDGEVVTRLGTKVDPRTAVIRVDGKRLPPVSEKVYLVLNK
PRGVVSTMSDPEGRRTLSDLVADRPERLFHVGRLDTDTSGLLLLTNDGDFAHRMAHPSYEVDKTYVAEVEGEVYRRTIKQ
LLEGVTLDDGPVTVSKARIVEATAAKSIVELVIHEGRNRIVRRLLDQVGHPVRRLTRTAIGPVSLGRLPSGELRDLTRQE
LGELLDTAQL

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=230, Percent_Identity=39.1304347826087, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790453, Length=238, Percent_Identity=33.6134453781513, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788510, Length=234, Percent_Identity=34.6153846153846, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI87081838, Length=177, Percent_Identity=35.5932203389831, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 27719; Mature: 27588

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPGIESDDDGLVRLQKLLAQSGVASRRKCEELMLEGHVVVDGEVVTRLGTKVDPRTAV
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCHHHHHHCCCCCCCEEE
IRVDGKRLPPVSEKVYLVLNKPRGVVSTMSDPEGRRTLSDLVADRPERLFHVGRLDTDTS
EEECCCCCCCCCCEEEEEEECCCCCEECCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCC
GLLLLTNDGDFAHRMAHPSYEVDKTYVAEVEGEVYRRTIKQLLEGVTLDDGPVTVSKARI
CEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHH
VEATAAKSIVELVIHEGRNRIVRRLLDQVGHPVRRLTRTAIGPVSLGRLPSGELRDLTRQ
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
ELGELLDTAQL
HHHHHHHHCCC
>Mature Secondary Structure 
TTPGIESDDDGLVRLQKLLAQSGVASRRKCEELMLEGHVVVDGEVVTRLGTKVDPRTAV
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCHHHHHHCCCCCCCEEE
IRVDGKRLPPVSEKVYLVLNKPRGVVSTMSDPEGRRTLSDLVADRPERLFHVGRLDTDTS
EEECCCCCCCCCCEEEEEEECCCCCEECCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCC
GLLLLTNDGDFAHRMAHPSYEVDKTYVAEVEGEVYRRTIKQLLEGVTLDDGPVTVSKARI
CEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHH
VEATAAKSIVELVIHEGRNRIVRRLLDQVGHPVRRLTRTAIGPVSLGRLPSGELRDLTRQ
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
ELGELLDTAQL
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]