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The map label for this gene is yliI [H]

Identifier: 119716272

GI number: 119716272

Start: 2184532

End: 2185695

Strand: Reverse

Name: yliI [H]

Synonym: Noca_2041

Alternate gene names: 119716272

Gene position: 2185695-2184532 (Counterclockwise)

Preceding gene: 119716273

Following gene: 119716271

Centisome position: 43.84

GC content: 72.42

Gene sequence:

>1164_bases
ATGCGCATGCTCGTTCTCGGACTGACCGCGATGCTCGGCCTGACGCTCACGACCGCCACGCCGGCCGACGCCCATGCCCC
CGCCACCGACACCGCCGCCGCGACGACGCAGGTTCCGGCACTGAGGGTCACCCGGCTGGTCACCGGCCTCGACCACCCCT
GGGACGTCCGGCCGATCGGCGACGGCCGGCTGATCTTCACCCAGCGCGACCGGGCCACCGTCTCGATCTGGGACGGCAGC
CGGACCCGGCTGGTGCAGGGCTTCCCGAGCGACTCGGTGTGGGTCTCCGGCGAGACCGGGCTGATGGGGCTCGAGGTCGA
CCCGTCGTTCGCGAGCAACCGCACGTTCTACACCTGCCAGGGCGGCTTCACCGCCGGTGGCGGGCACGACGTGCGCATCA
TCCGCTGGACGCTGCGCGACGACCTGGTCTCGATCTCGGGGAGCAAGCGGCTGCTCGGCGGACTGCCCGCCACCAGCGGA
CGGCACGGGGGTTGCCGGCTGCTGGCGGTCGGCAAGCGGCTGTACGCCGGCACCGGGGACGCCGCGACCGGCAGCACGCC
GGAGAACAAGAAGTCGCTGGGCGGCAAGACGCTGTGCCTGCTCGCCGCGACCGGCAAGCCCTGCGGGAGCAACCCGTTCG
CCGGGTCGAAGAACCACAACAAGCGCTACGTGCACACCTACGGCCACCGCAACGTCCAGGGCCTCGACCGGCGCCGCGAC
GGCACCCTGTGGTCGGTCGAGCAGGGCAGCTACCGCGACGACGAGGTCAACCGGCTGCGCAAGGGCGGCGACTACGGCTG
GAACCCGGTCCCGGGCTACGACGAGTCGGTGCCGATGACCGACCAGTCGCTGCCGGGCCGCCAGCGCGCCGCCGTATGGC
GCTCGGGCGACCCGACGCTGGCCACCTCCGGCGGCGGCTTCGTCTACGGCAAGCGATGGGGCGCCCTGGACGGCAGCTTC
GCGGTCGCCGCGCTCAAGGCGGAGAGGGTGCTGTTCCTCCAGCTCTCCGCATCCGGCAGGCTGCAGAGGGTGCGGGTGCC
GGCGGCGCTGCGTCAGCACGGCCGGATCCGCACGGTGGTCGACGGCCCCGGCTCGGTCGCCTACGTCACCACCGACAACG
GGAACGGGAACGACGCGATCCTCGTTGTCAGACCCACACGATGA

Upstream 100 bases:

>100_bases
GTCAAGGCCGGCACCTTCCCCGGCCCCGAGCACACCTTCTGACCCCGCCCGGACCCGTCGACAGGTGGTGATCGGGGCGC
CGACCGGGAAGGGTGGGCGC

Downstream 100 bases:

>100_bases
GAGAGCGGTGACGACACCCCGGTGGACACCCAGACCCTGATCAACCTCGCCCTGGTCCTGTTGTTCATCCTGGTCGGCGG
GGTGTTCGCCGGCACCGAGA

Product: glucose sorbosone dehydrogenase

Products: NA

Alternate protein names: Asd [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MRMLVLGLTAMLGLTLTTATPADAHAPATDTAAATTQVPALRVTRLVTGLDHPWDVRPIGDGRLIFTQRDRATVSIWDGS
RTRLVQGFPSDSVWVSGETGLMGLEVDPSFASNRTFYTCQGGFTAGGGHDVRIIRWTLRDDLVSISGSKRLLGGLPATSG
RHGGCRLLAVGKRLYAGTGDAATGSTPENKKSLGGKTLCLLAATGKPCGSNPFAGSKNHNKRYVHTYGHRNVQGLDRRRD
GTLWSVEQGSYRDDEVNRLRKGGDYGWNPVPGYDESVPMTDQSLPGRQRAAVWRSGDPTLATSGGGFVYGKRWGALDGSF
AVAALKAERVLFLQLSASGRLQRVRVPAALRQHGRIRTVVDGPGSVAYVTTDNGNGNDAILVVRPTR

Sequences:

>Translated_387_residues
MRMLVLGLTAMLGLTLTTATPADAHAPATDTAAATTQVPALRVTRLVTGLDHPWDVRPIGDGRLIFTQRDRATVSIWDGS
RTRLVQGFPSDSVWVSGETGLMGLEVDPSFASNRTFYTCQGGFTAGGGHDVRIIRWTLRDDLVSISGSKRLLGGLPATSG
RHGGCRLLAVGKRLYAGTGDAATGSTPENKKSLGGKTLCLLAATGKPCGSNPFAGSKNHNKRYVHTYGHRNVQGLDRRRD
GTLWSVEQGSYRDDEVNRLRKGGDYGWNPVPGYDESVPMTDQSLPGRQRAAVWRSGDPTLATSGGGFVYGKRWGALDGSF
AVAALKAERVLFLQLSASGRLQRVRVPAALRQHGRIRTVVDGPGSVAYVTTDNGNGNDAILVVRPTR
>Mature_387_residues
MRMLVLGLTAMLGLTLTTATPADAHAPATDTAAATTQVPALRVTRLVTGLDHPWDVRPIGDGRLIFTQRDRATVSIWDGS
RTRLVQGFPSDSVWVSGETGLMGLEVDPSFASNRTFYTCQGGFTAGGGHDVRIIRWTLRDDLVSISGSKRLLGGLPATSG
RHGGCRLLAVGKRLYAGTGDAATGSTPENKKSLGGKTLCLLAATGKPCGSNPFAGSKNHNKRYVHTYGHRNVQGLDRRRD
GTLWSVEQGSYRDDEVNRLRKGGDYGWNPVPGYDESVPMTDQSLPGRQRAAVWRSGDPTLATSGGGFVYGKRWGALDGSF
AVAALKAERVLFLQLSASGRLQRVRVPAALRQHGRIRTVVDGPGSVAYVTTDNGNGNDAILVVRPTR

Specific function: Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI124248546, Length=334, Percent_Identity=24.8502994011976, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1787060, Length=372, Percent_Identity=25.8064516129032, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 41379; Mature: 41379

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMLVLGLTAMLGLTLTTATPADAHAPATDTAAATTQVPALRVTRLVTGLDHPWDVRPIG
CEEEEEEHHHHHCEEEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCEEECC
DGRLIFTQRDRATVSIWDGSRTRLVQGFPSDSVWVSGETGLMGLEVDPSFASNRTFYTCQ
CCEEEEEECCCEEEEEECCCCEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCEEEEEC
GGFTAGGGHDVRIIRWTLRDDLVSISGSKRLLGGLPATSGRHGGCRLLAVGKRLYAGTGD
CCEECCCCCEEEEEEEEECCCEEEECCCCCEECCCCCCCCCCCCEEEEEECCEEECCCCC
AATGSTPENKKSLGGKTLCLLAATGKPCGSNPFAGSKNHNKRYVHTYGHRNVQGLDRRRD
CCCCCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
GTLWSVEQGSYRDDEVNRLRKGGDYGWNPVPGYDESVPMTDQSLPGRQRAAVWRSGDPTL
CCEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCEE
ATSGGGFVYGKRWGALDGSFAVAALKAERVLFLQLSASGRLQRVRVPAALRQHGRIRTVV
EECCCCEEEECEECCCCCCEEEEEEEECEEEEEEECCCCCEEEEECCHHHHHCCCEEEEE
DGPGSVAYVTTDNGNGNDAILVVRPTR
ECCCCEEEEECCCCCCCEEEEEEECCC
>Mature Secondary Structure
MRMLVLGLTAMLGLTLTTATPADAHAPATDTAAATTQVPALRVTRLVTGLDHPWDVRPIG
CEEEEEEHHHHHCEEEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCEEECC
DGRLIFTQRDRATVSIWDGSRTRLVQGFPSDSVWVSGETGLMGLEVDPSFASNRTFYTCQ
CCEEEEEECCCEEEEEECCCCEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCEEEEEC
GGFTAGGGHDVRIIRWTLRDDLVSISGSKRLLGGLPATSGRHGGCRLLAVGKRLYAGTGD
CCEECCCCCEEEEEEEEECCCEEEECCCCCEECCCCCCCCCCCCEEEEEECCEEECCCCC
AATGSTPENKKSLGGKTLCLLAATGKPCGSNPFAGSKNHNKRYVHTYGHRNVQGLDRRRD
CCCCCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
GTLWSVEQGSYRDDEVNRLRKGGDYGWNPVPGYDESVPMTDQSLPGRQRAAVWRSGDPTL
CCEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCEE
ATSGGGFVYGKRWGALDGSFAVAALKAERVLFLQLSASGRLQRVRVPAALRQHGRIRTVV
EECCCCEEEECEECCCCCCEEEEEEEECEEEEEEECCCCCEEEEECCHHHHHCCCEEEEE
DGPGSVAYVTTDNGNGNDAILVVRPTR
ECCCCEEEEECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]