BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is fabG [H]

Identifier: 119716080

GI number: 119716080

Start: 1971581

End: 1972309

Strand: Direct

Name: fabG [H]

Synonym: Noca_1847

Alternate gene names: 119716080

Gene position: 1971581-1972309 (Clockwise)

Preceding gene: 119716079

Following gene: 119716081

Centisome position: 39.54

GC content: 74.07

Gene sequence:

>729_bases
GTGAGCGCGGCCAAGGTCGCGGTGGTCACCGGGGGCTCCCGCGGCATCGGACGGGCCGTCGTGGTGGAGGCCGCGAGGCG
CGGGTACGACGTGGTGTTCAGCCACCGCGGCCGCGCCGACGACGCAGCGGAAACGATGGCCGCGACGGCGGACTCGGGAC
GCACGGTGCGCGGTGTGCTCGGCTCGATGGAGGACCCGGCCGACCTGACCCGTCTGGTCGACGCGGCCCGCGAGGTCGGG
GAGGTGCACCTCCTGGTCACCTGCGCGGGCTTCCTCGCCGACACCCGGCTGGCCGAGGTGACCGACGAGCACTGGTGGGC
CTCGCTCGACGTGCACGTCACCGCGCCGATGCTGCTGGCCAAGGAGCTGGCCGCCGACCTGGCCCGGGTCCGCGGCGCGA
TCGTCAACGTCGCCTCCGACGGGGGCGTCGCCGGCTCGGTCCACGGTGCGCCGTACGGGACCTCGAAGGCCGGCACCATC
GGGCTCGGCCACTCCCTTGCCCGCGAGCTCGCCCCGCACGTGCGGGTCAACACCCTTGCGCCGGGGCCGATCGCCACCGA
CATGTGGGACGCGGTGCCCGAGGCGAGTCGTCGGGCCGTCGAGGATGCGACCCCGCTCGGTCGGGTAGGGACAGCCGAGG
AGATCGCGCGGTGCGCGCTCGACCTCGCGTCGTGGACCTACGTGACCGGTCAGACCCTCGTCGTCAACGGCGGACGGGTC
ATGAAGTGA

Upstream 100 bases:

>100_bases
TCGCCGAGCCGCGCGAGATCGCCAAGGCGGGCCTGGACCTGTGCCACTGGACCTACGCGACCGGCCAGACGCTCGTGGTC
GACGGCGGACGGGTGATGAC

Downstream 100 bases:

>100_bases
ACGTCTTTCTTCCACCAACCACCCACGAGGAGTCGTGAGACCCATGTCAGAGAACAGTGTCGGGACCGTCATCATCGGCG
GAGGAATCGGCGGCGTCGCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSAAKVAVVTGGSRGIGRAVVVEAARRGYDVVFSHRGRADDAAETMAATADSGRTVRGVLGSMEDPADLTRLVDAAREVG
EVHLLVTCAGFLADTRLAEVTDEHWWASLDVHVTAPMLLAKELAADLARVRGAIVNVASDGGVAGSVHGAPYGTSKAGTI
GLGHSLARELAPHVRVNTLAPGPIATDMWDAVPEASRRAVEDATPLGRVGTAEEIARCALDLASWTYVTGQTLVVNGGRV
MK

Sequences:

>Translated_242_residues
MSAAKVAVVTGGSRGIGRAVVVEAARRGYDVVFSHRGRADDAAETMAATADSGRTVRGVLGSMEDPADLTRLVDAAREVG
EVHLLVTCAGFLADTRLAEVTDEHWWASLDVHVTAPMLLAKELAADLARVRGAIVNVASDGGVAGSVHGAPYGTSKAGTI
GLGHSLARELAPHVRVNTLAPGPIATDMWDAVPEASRRAVEDATPLGRVGTAEEIARCALDLASWTYVTGQTLVVNGGRV
MK
>Mature_241_residues
SAAKVAVVTGGSRGIGRAVVVEAARRGYDVVFSHRGRADDAAETMAATADSGRTVRGVLGSMEDPADLTRLVDAAREVGE
VHLLVTCAGFLADTRLAEVTDEHWWASLDVHVTAPMLLAKELAADLARVRGAIVNVASDGGVAGSVHGAPYGTSKAGTIG
LGHSLARELAPHVRVNTLAPGPIATDMWDAVPEASRRAVEDATPLGRVGTAEEIARCALDLASWTYVTGQTLVVNGGRVM
K

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=32.2448979591837, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=33.4677419354839, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=33.4615384615385, Blast_Score=97, Evalue=9e-21,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=33.7448559670782, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI33667109, Length=245, Percent_Identity=33.469387755102, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=28.3464566929134, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=32.1138211382114, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI66933014, Length=193, Percent_Identity=31.0880829015544, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=34.2541436464088, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=28.1746031746032, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=25.4826254826255, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=37.603305785124, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=30.0813008130081, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=28.099173553719, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=28.8617886178862, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=31.7269076305221, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=265, Percent_Identity=29.0566037735849, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=27.5303643724696, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=27.1317829457364, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=30.46875, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=28.6919831223629, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=25.9842519685039, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=28.1632653061224, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=33.739837398374, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=34.9794238683128, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=29.8449612403101, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=246, Percent_Identity=31.3008130081301, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=28.8461538461538, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=28.3524904214559, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=242, Percent_Identity=30.1652892561983, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=30.952380952381, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=29.4776119402985, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=27.1604938271605, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=30.0395256916996, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=27.3076923076923, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=25.8823529411765, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=25.8555133079848, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=28.8973384030418, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=27.1062271062271, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=27.6923076923077, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=27.4131274131274, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=26.6409266409266, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=194, Percent_Identity=29.3814432989691, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=28.2442748091603, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=26.4591439688716, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=28.7878787878788, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=185, Percent_Identity=29.1891891891892, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=25.1968503937008, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=26.5625, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=195, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=34.9206349206349, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=30.4, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=30.0411522633745, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=30.8, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=29.0836653386454, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=30.3643724696356, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=26.8482490272374, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25069; Mature: 24937

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAKVAVVTGGSRGIGRAVVVEAARRGYDVVFSHRGRADDAAETMAATADSGRTVRGVL
CCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHH
GSMEDPADLTRLVDAAREVGEVHLLVTCAGFLADTRLAEVTDEHWWASLDVHVTAPMLLA
CCCCCHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHH
KELAADLARVRGAIVNVASDGGVAGSVHGAPYGTSKAGTIGLGHSLARELAPHVRVNTLA
HHHHHHHHHHHHHHEEEECCCCCEECCCCCCCCCCCCCEEECCHHHHHHHCCCCEEEEEC
PGPIATDMWDAVPEASRRAVEDATPLGRVGTAEEIARCALDLASWTYVTGQTLVVNGGRV
CCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEEECCCEEEECCCEE
MK
CC
>Mature Secondary Structure 
SAAKVAVVTGGSRGIGRAVVVEAARRGYDVVFSHRGRADDAAETMAATADSGRTVRGVL
CCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHH
GSMEDPADLTRLVDAAREVGEVHLLVTCAGFLADTRLAEVTDEHWWASLDVHVTAPMLLA
CCCCCHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHH
KELAADLARVRGAIVNVASDGGVAGSVHGAPYGTSKAGTIGLGHSLARELAPHVRVNTLA
HHHHHHHHHHHHHHEEEECCCCCEECCCCCCCCCCCCCEEECCHHHHHHHCCCCEEEEEC
PGPIATDMWDAVPEASRRAVEDATPLGRVGTAEEIARCALDLASWTYVTGQTLVVNGGRV
CCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEEECCCEEEECCCEE
MK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]