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The map label for this gene is 119716081

Identifier: 119716081

GI number: 119716081

Start: 1972353

End: 1973489

Strand: Direct

Name: 119716081

Synonym: Noca_1848

Alternate gene names: NA

Gene position: 1972353-1973489 (Clockwise)

Preceding gene: 119716080

Following gene: 119716082

Centisome position: 39.56

GC content: 69.57

Gene sequence:

>1137_bases
ATGTCAGAGAACAGTGTCGGGACCGTCATCATCGGCGGAGGAATCGGCGGCGTCGCGCTCGCCTACTACCTCGCCGAGCT
CGGTGAGGCCGACATCACCGTCGTCGAGGGCCGCGAGCTCGCGAGCGGCTGCACCGGTGGTTCGCTCGGCGGGGTCCGGC
AGCAGTTCAGCACGCCCAACGAGGTCGAGTTGGCGCTGCGGGGTCGCACGTTCTGGCAGACCTTCGAGGAGACCTTCGAC
TACCCGTGCGCCTACCACCAGGACGGCTACCTGATGCTGACCGGGCGTCAGGAGATCTTCGAAAAGCTCGGTGAGGCCGC
CGAGGTGCAGCGCGCGGCGGGGGCTACGAACGTCGAGATGGTCGCGGCCGCGGACCTCACTGGCATCGTCCCCTGGCTCT
CGCCCGAGGGGCTGGTCGGTGGCTGCTGGACGCCGGACGACGGTCGCGTGAATCCGACCGACGGCGTCTACGGCCTGGCC
GCCGCTGCACGCAAGCTGGGGGTGAAGTTCCTCCAGCACACCCGGGTCGCCAAGATCGAGAAGGCCAAGGGCGGCTGGAC
ACTGCACACGCCGACGCCGATCACCGCGCGTCGCGTGATCGTCGTCGCCGGGCTTGGCTCGCCGGACCTGATGCGGCCGT
TCGGCCTGGATCTCCCGATCACGCCAATGATGGTGCACTACGCCTTCACGACCCCGGTGATCTCCGACCAGGCGCTGCCG
ATGACCATCGACCTCGACACCGGCTTCTGCGTCGAGCGCGAGCAGGACGCCGCGGTGCTCACGATCCTGGAGTCGTCGTA
CGCCGAGGGCTACGGCGTGGACGACATGCTCGCCGAGTTCGCCGAGGCCGCCGCCATCCGGGCCCCGATCTTCACCGAGG
TGTCCATCCGCTCGACGATCAGTGCTTCCGCGGACGCGACCGGGGGCGACGGCCACCCGTTCATCGGCGAGGTCGAGCCG
GGCCTGTGGACCATGACCGGGTTCGACGGCCACGGCACCATGCAGGGCCCGGCGATCGCCAAGTTCACCGCGAACCTGAT
CGCCGGCATCCCGGACCCGGTGCTGGACCCGGCGATCTTCGACCCGCACCGCGGGCTGACCGAGACCCAGGAGTGGCTGC
GGGCGGCCCGGAAGTGA

Upstream 100 bases:

>100_bases
TGGACCTACGTGACCGGTCAGACCCTCGTCGTCAACGGCGGACGGGTCATGAAGTGAACGTCTTTCTTCCACCAACCACC
CACGAGGAGTCGTGAGACCC

Downstream 100 bases:

>100_bases
GCACCCGGGACAAGGTCGCGATCGTGACCGCGGGCAGCTCGGGCATCGGGGCGGGTATCGTCCGCGCGCTCGCCGACGAC
CACCGGGTGGTGGTGCTGGC

Product: FAD dependent oxidoreductase

Products: glycine; formaldehyde; H2O2

Alternate protein names: Dimethylglycine Dehydrogenase; Glycine Cleavage T-Protein; Sarcosine Oxidase Subunit Beta; Sarcosine Oxidase Beta Subunit; Aminomethyl Transferase Family Protein; Oxidoreductase; FAD Dependent Oxidoreductase/Aminomethyl Transferase; Glycine/D-Amino Acid Oxidase Deaminating; Glycine Oxidase ThiO; Sarcosine Oxidase Beta Subunit Family Protein; Sarcosine Oxidase; Proline Dehydrogenase Beta Subunit; FAD-Dependent Oxidoreductase; Dye-Linked L-Proline Dehydrogenase Beta2 Subunit; SoxB-Like Sarcosine Oxidase Beta Subunit ; Glycine Cleavage System T Protein; Sarcosine Dehydrogenase; Sarcosine Oxidase Subunit Beta Family Protein; Oxidoreductase-Like Protein; Fad Dependent Oxidoreductase

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MSENSVGTVIIGGGIGGVALAYYLAELGEADITVVEGRELASGCTGGSLGGVRQQFSTPNEVELALRGRTFWQTFEETFD
YPCAYHQDGYLMLTGRQEIFEKLGEAAEVQRAAGATNVEMVAAADLTGIVPWLSPEGLVGGCWTPDDGRVNPTDGVYGLA
AAARKLGVKFLQHTRVAKIEKAKGGWTLHTPTPITARRVIVVAGLGSPDLMRPFGLDLPITPMMVHYAFTTPVISDQALP
MTIDLDTGFCVEREQDAAVLTILESSYAEGYGVDDMLAEFAEAAAIRAPIFTEVSIRSTISASADATGGDGHPFIGEVEP
GLWTMTGFDGHGTMQGPAIAKFTANLIAGIPDPVLDPAIFDPHRGLTETQEWLRAARK

Sequences:

>Translated_378_residues
MSENSVGTVIIGGGIGGVALAYYLAELGEADITVVEGRELASGCTGGSLGGVRQQFSTPNEVELALRGRTFWQTFEETFD
YPCAYHQDGYLMLTGRQEIFEKLGEAAEVQRAAGATNVEMVAAADLTGIVPWLSPEGLVGGCWTPDDGRVNPTDGVYGLA
AAARKLGVKFLQHTRVAKIEKAKGGWTLHTPTPITARRVIVVAGLGSPDLMRPFGLDLPITPMMVHYAFTTPVISDQALP
MTIDLDTGFCVEREQDAAVLTILESSYAEGYGVDDMLAEFAEAAAIRAPIFTEVSIRSTISASADATGGDGHPFIGEVEP
GLWTMTGFDGHGTMQGPAIAKFTANLIAGIPDPVLDPAIFDPHRGLTETQEWLRAARK
>Mature_377_residues
SENSVGTVIIGGGIGGVALAYYLAELGEADITVVEGRELASGCTGGSLGGVRQQFSTPNEVELALRGRTFWQTFEETFDY
PCAYHQDGYLMLTGRQEIFEKLGEAAEVQRAAGATNVEMVAAADLTGIVPWLSPEGLVGGCWTPDDGRVNPTDGVYGLAA
AARKLGVKFLQHTRVAKIEKAKGGWTLHTPTPITARRVIVVAGLGSPDLMRPFGLDLPITPMMVHYAFTTPVISDQALPM
TIDLDTGFCVEREQDAAVLTILESSYAEGYGVDDMLAEFAEAAAIRAPIFTEVSIRSTISASADATGGDGHPFIGEVEPG
LWTMTGFDGHGTMQGPAIAKFTANLIAGIPDPVLDPAIFDPHRGLTETQEWLRAARK

Specific function: Unknown

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24797151, Length=384, Percent_Identity=23.9583333333333, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI197927446, Length=403, Percent_Identity=24.317617866005, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI21361378, Length=403, Percent_Identity=24.317617866005, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI8923708, Length=393, Percent_Identity=22.3918575063613, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20130091, Length=394, Percent_Identity=25.6345177664975, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20129729, Length=392, Percent_Identity=28.3163265306122, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17985989, Length=378, Percent_Identity=24.8677248677249, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.5.3.1

Molecular weight: Translated: 40176; Mature: 40045

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENSVGTVIIGGGIGGVALAYYLAELGEADITVVEGRELASGCTGGSLGGVRQQFSTPN
CCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCHHHHHCCCCC
EVELALRGRTFWQTFEETFDYPCAYHQDGYLMLTGRQEIFEKLGEAAEVQRAAGATNVEM
CEEEEECCCHHHHHHHHHCCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCEEE
VAAADLTGIVPWLSPEGLVGGCWTPDDGRVNPTDGVYGLAAAARKLGVKFLQHTRVAKIE
EEECCHHHCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHE
KAKGGWTLHTPTPITARRVIVVAGLGSPDLMRPFGLDLPITPMMVHYAFTTPVISDQALP
ECCCCEEEECCCCCCCCEEEEEEECCCCHHCCCCCCCCCCHHHEEEEEHCCCCCCCCCCE
MTIDLDTGFCVEREQDAAVLTILESSYAEGYGVDDMLAEFAEAAAIRAPIFTEVSIRSTI
EEEECCCCCEEECCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHH
SASADATGGDGHPFIGEVEPGLWTMTGFDGHGTMQGPAIAKFTANLIAGIPDPVLDPAIF
CCCCCCCCCCCCCCCEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
DPHRGLTETQEWLRAARK
CCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SENSVGTVIIGGGIGGVALAYYLAELGEADITVVEGRELASGCTGGSLGGVRQQFSTPN
CCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCHHHHHCCCCC
EVELALRGRTFWQTFEETFDYPCAYHQDGYLMLTGRQEIFEKLGEAAEVQRAAGATNVEM
CEEEEECCCHHHHHHHHHCCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCEEE
VAAADLTGIVPWLSPEGLVGGCWTPDDGRVNPTDGVYGLAAAARKLGVKFLQHTRVAKIE
EEECCHHHCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHE
KAKGGWTLHTPTPITARRVIVVAGLGSPDLMRPFGLDLPITPMMVHYAFTTPVISDQALP
ECCCCEEEECCCCCCCCEEEEEEECCCCHHCCCCCCCCCCHHHEEEEEHCCCCCCCCCCE
MTIDLDTGFCVEREQDAAVLTILESSYAEGYGVDDMLAEFAEAAAIRAPIFTEVSIRSTI
EEEECCCCCEEECCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHH
SASADATGGDGHPFIGEVEPGLWTMTGFDGHGTMQGPAIAKFTANLIAGIPDPVLDPAIF
CCCCCCCCCCCCCCCEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
DPHRGLTETQEWLRAARK
CCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: sarcosine; H2O; O2

Specific reaction: sarcosine + H2O + O2 = glycine + formaldehyde + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA