BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 119716079

GI number: 119716079

Start: 1970859

End: 1971584

Strand: Direct

Name: fabG [H]

Synonym: Noca_1846

Alternate gene names: 119716079

Gene position: 1970859-1971584 (Clockwise)

Preceding gene: 119716078

Following gene: 119716080

Centisome position: 39.53

GC content: 73.42

Gene sequence:

>726_bases
GTGACCAAGCCGGGCTCGGTCGTCGTCACCGGCGGCTCGCGTGGGATCGGCAGGGCCTTCGTCGTCGAGGCCGCGCGACG
CGGGTACGACGTGTTCTTCACCCATCGGGGACGTGCCTCGGACGCCGCGGACACCGTAGCCGCCGCGGGGGACACGACGG
CCGTGCGCGCCGTGGAGGCGGACCTGCTCGACCGGACCGCGCTCGAGGGCGCGGTCGCGACGGTCCTCGAGCACGGGCCG
GTGCACATCCTGGTCAACAACGCCGGCACGATGGCCCACGGCCTCCTCGGCGAGCTGACCGAGGAGGGCTGGCGCCGGTC
CTTCGACGTGCATGTGACCGCCCCGATGGTCCTGGCCCGCGGGTTCGCCGAGTCGTTGGCGGCAACCGGTGGTGCGATCC
TCAACGTGTCCTCCACCGGCGGCGTCGTCGGATCGGTGCACGGCGCCGCCTACGGTGCCAGCAAGGCGGCGATCCTCGGC
CTGACCAAGTCGCTGGCCCGCGAGCTCGCCCCGTCCGTGCGGGTGAACACGCTGGCACCCGGGCCGGCGGGCACCGACAT
GTATGCCGACCTGCCCGAGGACGAGCGCCGTGCCGTCGAGGACGAGACGCCGCTCGGTCGCGTCGCCGAGCCGCGCGAGA
TCGCCAAGGCGGGCCTGGACCTGTGCCACTGGACCTACGCGACCGGCCAGACGCTCGTGGTCGACGGCGGACGGGTGATG
ACGTGA

Upstream 100 bases:

>100_bases
TCACCGAGGACTTCCCGGCGCGGTCCGCGGTCGCGGTGCACCAGCTCCCGATCGGCGCGGTCTTCGAGATCGAGGCGTGG
GCCTACCGCGGGAACCAGCG

Downstream 100 bases:

>100_bases
GCGCGGCCAAGGTCGCGGTGGTCACCGGGGGCTCCCGCGGCATCGGACGGGCCGTCGTGGTGGAGGCCGCGAGGCGCGGG
TACGACGTGGTGTTCAGCCA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTKPGSVVVTGGSRGIGRAFVVEAARRGYDVFFTHRGRASDAADTVAAAGDTTAVRAVEADLLDRTALEGAVATVLEHGP
VHILVNNAGTMAHGLLGELTEEGWRRSFDVHVTAPMVLARGFAESLAATGGAILNVSSTGGVVGSVHGAAYGASKAAILG
LTKSLARELAPSVRVNTLAPGPAGTDMYADLPEDERRAVEDETPLGRVAEPREIAKAGLDLCHWTYATGQTLVVDGGRVM
T

Sequences:

>Translated_241_residues
MTKPGSVVVTGGSRGIGRAFVVEAARRGYDVFFTHRGRASDAADTVAAAGDTTAVRAVEADLLDRTALEGAVATVLEHGP
VHILVNNAGTMAHGLLGELTEEGWRRSFDVHVTAPMVLARGFAESLAATGGAILNVSSTGGVVGSVHGAAYGASKAAILG
LTKSLARELAPSVRVNTLAPGPAGTDMYADLPEDERRAVEDETPLGRVAEPREIAKAGLDLCHWTYATGQTLVVDGGRVM
T
>Mature_240_residues
TKPGSVVVTGGSRGIGRAFVVEAARRGYDVFFTHRGRASDAADTVAAAGDTTAVRAVEADLLDRTALEGAVATVLEHGPV
HILVNNAGTMAHGLLGELTEEGWRRSFDVHVTAPMVLARGFAESLAATGGAILNVSSTGGVVGSVHGAAYGASKAAILGL
TKSLARELAPSVRVNTLAPGPAGTDMYADLPEDERRAVEDETPLGRVAEPREIAKAGLDLCHWTYATGQTLVVDGGRVMT

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=233, Percent_Identity=35.1931330472103, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI32483357, Length=238, Percent_Identity=32.3529411764706, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI7705925, Length=238, Percent_Identity=34.453781512605, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=30.8, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI19923817, Length=249, Percent_Identity=28.1124497991968, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI5031737, Length=237, Percent_Identity=30.8016877637131, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI66933014, Length=195, Percent_Identity=29.2307692307692, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI33667109, Length=184, Percent_Identity=33.695652173913, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4504505, Length=227, Percent_Identity=30.3964757709251, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI59889578, Length=173, Percent_Identity=30.0578034682081, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=228, Percent_Identity=29.8245614035088, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI10190704, Length=243, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723750, Length=241, Percent_Identity=27.3858921161826, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4758504, Length=251, Percent_Identity=28.2868525896414, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI225579078, Length=209, Percent_Identity=34.4497607655502, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI126723191, Length=104, Percent_Identity=38.4615384615385, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI302344755, Length=104, Percent_Identity=38.4615384615385, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=34.1666666666667, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=33.0578512396694, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=29.5081967213115, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=33.0612244897959, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=29.8804780876494, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=33.4630350194552, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=31.0483870967742, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=27.2357723577236, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789378, Length=240, Percent_Identity=30.4166666666667, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=30.0411522633745, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787891, Length=246, Percent_Identity=28.8617886178862, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789057, Length=180, Percent_Identity=28.8888888888889, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=32.2314049586777, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI25147288, Length=239, Percent_Identity=32.6359832635983, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=259, Percent_Identity=29.3436293436293, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=32.3770491803279, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=236, Percent_Identity=31.3559322033898, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=31.7269076305221, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=31.9066147859922, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=30.5882352941176, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=31.2741312741313, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=253, Percent_Identity=32.0158102766798, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.9693486590038, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=252, Percent_Identity=29.3650793650794, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=253, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=252, Percent_Identity=28.1746031746032, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=252, Percent_Identity=30.1587301587302, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=242, Percent_Identity=29.7520661157025, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=254, Percent_Identity=27.5590551181102, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=30.0813008130081, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=254, Percent_Identity=29.5275590551181, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=252, Percent_Identity=29.7619047619048, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=255, Percent_Identity=30.5882352941176, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=31.2169312169312, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=255, Percent_Identity=30.5882352941176, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=253, Percent_Identity=27.6679841897233, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=248, Percent_Identity=29.0322580645161, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=28.3422459893048, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=200, Percent_Identity=31, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=32.6771653543307, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=32.9411764705882, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI23397609, Length=242, Percent_Identity=32.6446280991736, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639444, Length=239, Percent_Identity=30.1255230125523, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355319, Length=243, Percent_Identity=32.5102880658436, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24643142, Length=237, Percent_Identity=32.4894514767932, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17737361, Length=263, Percent_Identity=28.8973384030418, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=30.0813008130081, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644337, Length=199, Percent_Identity=31.6582914572864, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584752, Length=184, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24826; Mature: 24695

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPGSVVVTGGSRGIGRAFVVEAARRGYDVFFTHRGRASDAADTVAAAGDTTAVRAVEA
CCCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCCHHHHHHHH
DLLDRTALEGAVATVLEHGPVHILVNNAGTMAHGLLGELTEEGWRRSFDVHVTAPMVLAR
HHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEECHHHHHHH
GFAESLAATGGAILNVSSTGGVVGSVHGAAYGASKAAILGLTKSLARELAPSVRVNTLAP
HHHHHHHHCCCEEEEECCCCCEEECCCCHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
GPAGTDMYADLPEDERRAVEDETPLGRVAEPREIAKAGLDLCHWTYATGQTLVVDGGRVM
CCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCEEEECCCEEC
T
C
>Mature Secondary Structure 
TKPGSVVVTGGSRGIGRAFVVEAARRGYDVFFTHRGRASDAADTVAAAGDTTAVRAVEA
CCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCCHHHHHHHH
DLLDRTALEGAVATVLEHGPVHILVNNAGTMAHGLLGELTEEGWRRSFDVHVTAPMVLAR
HHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEECHHHHHHH
GFAESLAATGGAILNVSSTGGVVGSVHGAAYGASKAAILGLTKSLARELAPSVRVNTLAP
HHHHHHHHCCCEEEEECCCCCEEECCCCHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
GPAGTDMYADLPEDERRAVEDETPLGRVAEPREIAKAGLDLCHWTYATGQTLVVDGGRVM
CCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCEEEECCCEEC
T
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]