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The map label for this gene is kstR2 [H]

Identifier: 119716061

GI number: 119716061

Start: 1948073

End: 1948663

Strand: Reverse

Name: kstR2 [H]

Synonym: Noca_1827

Alternate gene names: 119716061

Gene position: 1948663-1948073 (Counterclockwise)

Preceding gene: 119716067

Following gene: 119716060

Centisome position: 39.08

GC content: 67.01

Gene sequence:

>591_bases
ATGAGCGACACGAAGGACACCTCCCGCGCCGAGGCGACCCGAGCCCGCCTGGCCGAGGCCGCGGTGGACGCGTTCGCCGA
ACGCGGCTATCACGGCACCACCACCCGGGACATCGCCAGCGCAGCGGGGATGTCCCCCGCCGCGCTCTACGTGCACCACA
ACTCGAAGGAGGAGCTCCTCTACCTCATCTCCAAGGCAGGCCATGAGCAGGCGCTGACCGTGCTCCGGCAGGCCGTCGAC
GCCTCCGAGGACCCGGTCGAGCAGTTGCGCGCAGTGATGCGTGGCTTCGTCGAACACCACGTTCGCACGCACACGTCGGC
TCGGATCGTGAACTACGAACTCGCCGCGCTTTCCCCGCAGCACCTTGCCGAGATGGCCGGAATACGCAGCGAGATCGACG
CATTGTTCTCCGATCTGGTGAATCGCGGCATCTCCACCGGCGCGTTCCACACGCGGTATCCGCGGATGGCCACGGTGGCG
CTCCAGTCGCTCGGGATCGACATCGCACGCTGGTACCGCGAAGGTGGCTGGTCGGAGGAGGAGATCGCCGACGGCTACGT
GGACATCGCGTTACGAATCGTCGGAGCGTGA

Upstream 100 bases:

>100_bases
TAGGCGATATTGCTCGAACCGCTGCCCAGTCGTCAAGCGCCGGAGACCCCACAGGCGCCTTACTCTGCTGCGACTGGTCC
TACGAAGAGGGAAGGCGCAG

Downstream 100 bases:

>100_bases
GGTGCCAAACAGCGACACGGAGTCTGATCATTCGGCCGACCAGGCCGAGCCCACCGCGGCAGGCTACTGCGCTCCCTCCA
GTTCGAGCGGTTGGGGTCAG

Product: regulatory protein TetR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSDTKDTSRAEATRARLAEAAVDAFAERGYHGTTTRDIASAAGMSPAALYVHHNSKEELLYLISKAGHEQALTVLRQAVD
ASEDPVEQLRAVMRGFVEHHVRTHTSARIVNYELAALSPQHLAEMAGIRSEIDALFSDLVNRGISTGAFHTRYPRMATVA
LQSLGIDIARWYREGGWSEEEIADGYVDIALRIVGA

Sequences:

>Translated_196_residues
MSDTKDTSRAEATRARLAEAAVDAFAERGYHGTTTRDIASAAGMSPAALYVHHNSKEELLYLISKAGHEQALTVLRQAVD
ASEDPVEQLRAVMRGFVEHHVRTHTSARIVNYELAALSPQHLAEMAGIRSEIDALFSDLVNRGISTGAFHTRYPRMATVA
LQSLGIDIARWYREGGWSEEEIADGYVDIALRIVGA
>Mature_195_residues
SDTKDTSRAEATRARLAEAAVDAFAERGYHGTTTRDIASAAGMSPAALYVHHNSKEELLYLISKAGHEQALTVLRQAVDA
SEDPVEQLRAVMRGFVEHHVRTHTSARIVNYELAALSPQHLAEMAGIRSEIDALFSDLVNRGISTGAFHTRYPRMATVAL
QSLGIDIARWYREGGWSEEEIADGYVDIALRIVGA

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21476; Mature: 21345

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTKDTSRAEATRARLAEAAVDAFAERGYHGTTTRDIASAAGMSPAALYVHHNSKEELL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEECCHHHHH
YLISKAGHEQALTVLRQAVDASEDPVEQLRAVMRGFVEHHVRTHTSARIVNYELAALSPQ
HHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCHH
HLAEMAGIRSEIDALFSDLVNRGISTGAFHTRYPRMATVALQSLGIDIARWYREGGWSEE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHCHHHHHHHHHCCCCHH
EIADGYVDIALRIVGA
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDTKDTSRAEATRARLAEAAVDAFAERGYHGTTTRDIASAAGMSPAALYVHHNSKEELL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEECCHHHHH
YLISKAGHEQALTVLRQAVDASEDPVEQLRAVMRGFVEHHVRTHTSARIVNYELAALSPQ
HHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCHH
HLAEMAGIRSEIDALFSDLVNRGISTGAFHTRYPRMATVALQSLGIDIARWYREGGWSEE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHCHHHHHHHHHCCCCHH
EIADGYVDIALRIVGA
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]