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The map label for this gene is cutL [H]

Identifier: 119714855

GI number: 119714855

Start: 628630

End: 631035

Strand: Direct

Name: cutL [H]

Synonym: Noca_0596

Alternate gene names: 119714855

Gene position: 628630-631035 (Clockwise)

Preceding gene: 119714854

Following gene: 119714856

Centisome position: 12.61

GC content: 63.38

Gene sequence:

>2406_bases
GTGAAGAAGCTCGACAGTCACCAGCACATGAAGACGCCGGTCGTCGCTGCTCGGTCGGTCGGGACCCGAGTGCTGCGGTC
TGAAGACCCGCGGTTGCTCACCGGCCGAGGTGAGTTCATCGCCGATATCGACCTCCCGCGCCAGCTCCACGTGGCTTTCA
TACGAAGTCCTGTTGCACACGCACGAATCACTAATCTCGACTTGTCCGCAATCCGCGACGCGGACGGCGTGGCACTGGCG
TGGTCCGGCAAGGACGTCGCCCCCTTCTGCGAGGGCCTCGTCGGCGAGATGGCGGTTGAAGGCTGCTTTCCGACCACGAT
GCCGCTGCTCGCGGGAGATGAAGTCGTCTACGTCGGTGAGCCTGTCGCCGTGGTCGTGGCTGACTCGCGCTACGCGGCAG
AGGACGCTTGTGAACTGATCGATTGGGACTTCGACGAGCTGCCTGCCGTCACCAACGTGGACGCAGCCGCCGGTGGCGGT
CCAGTCGCGAACCCGCAGCTGCCCGATAACATCGGACTCAACGGTGGCGCGAGCTTCGGTGACGTTTCAGGAGCCTTCGA
ACAGGCCCACCAGGTCGTCGAGGGTCGGTTCTACACCTGCCGTGTCTCGGCGGCTCCTATGGAGACGCGCGGCGTGATCG
CCGACTACGAATGGGCGTCGAAGGCGCTACGTCTGTGGTCGAACACCCAGATGCCGCACTATCTGAAGTACATGCTGACG
GCGTACCTCGGTTTCCCGGAGCAAAGCGTCGAAGTCATCACTCCCGACACCGGCGGTGGGTTCGGCTTGAAGGCGCACGT
CTATCCCGAAGAGATGTTGCTGCCACTCATCGCCAGGGAAGTCGGCCGGCCTGTCAAGTGGATCGAAGACCGTCGAGAGA
ACCTCATCGCCGGCGCACACGCGCATGAGCAGTACGTTGACATCGCGTACGCGCTCGATGCCGACGGCAAGATCACAGGA
GTCCGTACACACGCGCTCGGTGACGGCGGGGCGTATCACCTGCCACCATGGTCGATGGCCGTGGAGCCGTGGTGTGCCGC
AGTGATGACCCCCACCGGCATCTACGACGTACCGGCTGTGGAGTACACCTACAAGGCCGCGGCCACCAACAAGACGCCCG
TCGGCGCCTACCGCGGGGTGGGCTACATGGCCGGGACATTCGCTCGTGAGTGCCTCGCCGACGATGCCGCGCGTGCACTG
CGCATGTCGCCCTTCGACTTCCGTCGACACAATGTCGTTCGCGAGTTCCCGTGGACCAATCCTCAGGGCATTGTTTACCA
GGAGGGAAGCTGGCTGCAGACAATCGACGCACTCGAGGAGATGGTCGACTACCCGGCCTTTCTGCGTCGGCAGACCGAGC
TGCGCAAGGAGGGGCGCTACATCGGGCTGGGCCTCAGCTGCTTCGTCGAGAGCAGCGGCGAGAGTACGGCGACCAGCCTC
GAGCACGGACTCGGCGACGTTTACCATGACACCGCCACAGTCCGGCTGAACCCCAATGGCACCGCCAACGTGACGATCGG
TCTGTCGGCGCAGGGCCAAGGACTCGCCACGACCATGGCCCAGATGGCAGCCGACACCTTGGGCATCAAGGTGGAGGACG
TCAGCGTCCAGACAGCGCGGTCGACCTCTCACGCCTACGGCTCAGGCACCCTCGGTAGCCGCGGCGCAGTCGTTGCAGGT
GGAGCCGTGTCACGAGCAGCAGACGTCGTCAGAGAGAAGGTGCGGCAGGTAGCCGCCCACATGCTCGAAGCATCGACCGA
TGACATCGAGCTGGTAGACGGTCTCGCTTCGATCAAGGGCATCTCGGACGCCTCGTTGTCCATCGCCGACGTTGCCACCG
CAATCTATTTCGACCTCGACTCGTGGCCAGAGGACTTCGAGCCAACCCTCGAAGCCACCCAGGCCTACGATCCTTCCCAG
GCGATGTTCAGCAACGGCGGCCACGCGATCATGGTGGAACTAGATGCCGAGACCGGCTTCGTGCGCTTCGAGAAGATCTT
TTCAGTCGAAGACTGCGGCACGGTCATCAACCCCAACATCGTAGAGGGACAGATCCGCGGCGGAGTCATACAAGGCATCG
GTGCATCCGTATTCGAGGAACTAGCCTATGACGAGTCTGGCCAGATTCTCACTACCACTTTCCTCGACTACGGACTGCCG
ACAATGGACGTCGCCCCGCCGTTCGAGATCAACCACCTCGAGACGCCCTCCTCGCACTCCGCCTCGGGCGTGAAGGGGAT
GGGAGAGTCGGGCCTCATCGCGGCTCCCGCTGCGGTTCTGAACGCCGTCAACGACGCCCTTTCACCATTCGGCGTGGTGT
TGCGCGACCTGCCACTGACGCCTGAGAAGGTGCTTGGTGCCATGTCTGGAGCGAAGGTAGCGACCGGTTTGGCAGAGCGG
TCGTGA

Upstream 100 bases:

>100_bases
CGATGTCGGGTTCGCTATGTCGATGCACGGGATACCAGACCATCATCTCTGCCATCGAACAAGCGGCGGCCGAGGGTCAG
AGCGACACGGAGGACGACCA

Downstream 100 bases:

>100_bases
CCAGCGGGGACGGCTCGCGCACGAATCGTCTGCGCGTTGCCCTGCTTCAGGTCGCTTATGGCGACGACGAGAGTCTGTCC
GATCGGGTTCAGCGAGTCAG

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 801; Mature: 801

Protein sequence:

>801_residues
MKKLDSHQHMKTPVVAARSVGTRVLRSEDPRLLTGRGEFIADIDLPRQLHVAFIRSPVAHARITNLDLSAIRDADGVALA
WSGKDVAPFCEGLVGEMAVEGCFPTTMPLLAGDEVVYVGEPVAVVVADSRYAAEDACELIDWDFDELPAVTNVDAAAGGG
PVANPQLPDNIGLNGGASFGDVSGAFEQAHQVVEGRFYTCRVSAAPMETRGVIADYEWASKALRLWSNTQMPHYLKYMLT
AYLGFPEQSVEVITPDTGGGFGLKAHVYPEEMLLPLIAREVGRPVKWIEDRRENLIAGAHAHEQYVDIAYALDADGKITG
VRTHALGDGGAYHLPPWSMAVEPWCAAVMTPTGIYDVPAVEYTYKAAATNKTPVGAYRGVGYMAGTFARECLADDAARAL
RMSPFDFRRHNVVREFPWTNPQGIVYQEGSWLQTIDALEEMVDYPAFLRRQTELRKEGRYIGLGLSCFVESSGESTATSL
EHGLGDVYHDTATVRLNPNGTANVTIGLSAQGQGLATTMAQMAADTLGIKVEDVSVQTARSTSHAYGSGTLGSRGAVVAG
GAVSRAADVVREKVRQVAAHMLEASTDDIELVDGLASIKGISDASLSIADVATAIYFDLDSWPEDFEPTLEATQAYDPSQ
AMFSNGGHAIMVELDAETGFVRFEKIFSVEDCGTVINPNIVEGQIRGGVIQGIGASVFEELAYDESGQILTTTFLDYGLP
TMDVAPPFEINHLETPSSHSASGVKGMGESGLIAAPAAVLNAVNDALSPFGVVLRDLPLTPEKVLGAMSGAKVATGLAER
S

Sequences:

>Translated_801_residues
MKKLDSHQHMKTPVVAARSVGTRVLRSEDPRLLTGRGEFIADIDLPRQLHVAFIRSPVAHARITNLDLSAIRDADGVALA
WSGKDVAPFCEGLVGEMAVEGCFPTTMPLLAGDEVVYVGEPVAVVVADSRYAAEDACELIDWDFDELPAVTNVDAAAGGG
PVANPQLPDNIGLNGGASFGDVSGAFEQAHQVVEGRFYTCRVSAAPMETRGVIADYEWASKALRLWSNTQMPHYLKYMLT
AYLGFPEQSVEVITPDTGGGFGLKAHVYPEEMLLPLIAREVGRPVKWIEDRRENLIAGAHAHEQYVDIAYALDADGKITG
VRTHALGDGGAYHLPPWSMAVEPWCAAVMTPTGIYDVPAVEYTYKAAATNKTPVGAYRGVGYMAGTFARECLADDAARAL
RMSPFDFRRHNVVREFPWTNPQGIVYQEGSWLQTIDALEEMVDYPAFLRRQTELRKEGRYIGLGLSCFVESSGESTATSL
EHGLGDVYHDTATVRLNPNGTANVTIGLSAQGQGLATTMAQMAADTLGIKVEDVSVQTARSTSHAYGSGTLGSRGAVVAG
GAVSRAADVVREKVRQVAAHMLEASTDDIELVDGLASIKGISDASLSIADVATAIYFDLDSWPEDFEPTLEATQAYDPSQ
AMFSNGGHAIMVELDAETGFVRFEKIFSVEDCGTVINPNIVEGQIRGGVIQGIGASVFEELAYDESGQILTTTFLDYGLP
TMDVAPPFEINHLETPSSHSASGVKGMGESGLIAAPAAVLNAVNDALSPFGVVLRDLPLTPEKVLGAMSGAKVATGLAER
S
>Mature_801_residues
MKKLDSHQHMKTPVVAARSVGTRVLRSEDPRLLTGRGEFIADIDLPRQLHVAFIRSPVAHARITNLDLSAIRDADGVALA
WSGKDVAPFCEGLVGEMAVEGCFPTTMPLLAGDEVVYVGEPVAVVVADSRYAAEDACELIDWDFDELPAVTNVDAAAGGG
PVANPQLPDNIGLNGGASFGDVSGAFEQAHQVVEGRFYTCRVSAAPMETRGVIADYEWASKALRLWSNTQMPHYLKYMLT
AYLGFPEQSVEVITPDTGGGFGLKAHVYPEEMLLPLIAREVGRPVKWIEDRRENLIAGAHAHEQYVDIAYALDADGKITG
VRTHALGDGGAYHLPPWSMAVEPWCAAVMTPTGIYDVPAVEYTYKAAATNKTPVGAYRGVGYMAGTFARECLADDAARAL
RMSPFDFRRHNVVREFPWTNPQGIVYQEGSWLQTIDALEEMVDYPAFLRRQTELRKEGRYIGLGLSCFVESSGESTATSL
EHGLGDVYHDTATVRLNPNGTANVTIGLSAQGQGLATTMAQMAADTLGIKVEDVSVQTARSTSHAYGSGTLGSRGAVVAG
GAVSRAADVVREKVRQVAAHMLEASTDDIELVDGLASIKGISDASLSIADVATAIYFDLDSWPEDFEPTLEATQAYDPSQ
AMFSNGGHAIMVELDAETGFVRFEKIFSVEDCGTVINPNIVEGQIRGGVIQGIGASVFEELAYDESGQILTTTFLDYGLP
TMDVAPPFEINHLETPSSHSASGVKGMGESGLIAAPAAVLNAVNDALSPFGVVLRDLPLTPEKVLGAMSGAKVATGLAER
S

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=774, Percent_Identity=23.9018087855297, Blast_Score=156, Evalue=7e-38,
Organism=Homo sapiens, GI71773480, Length=774, Percent_Identity=24.031007751938, Blast_Score=143, Evalue=6e-34,
Organism=Escherichia coli, GI1789230, Length=764, Percent_Identity=29.4502617801047, Blast_Score=256, Evalue=4e-69,
Organism=Escherichia coli, GI1789246, Length=820, Percent_Identity=25.609756097561, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1786478, Length=797, Percent_Identity=25.7214554579674, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17540638, Length=789, Percent_Identity=22.3067173637516, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17539860, Length=786, Percent_Identity=21.882951653944, Blast_Score=126, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32566215, Length=789, Percent_Identity=21.2927756653992, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17737937, Length=784, Percent_Identity=23.9795918367347, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24647197, Length=775, Percent_Identity=22.4516129032258, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647195, Length=777, Percent_Identity=22.3938223938224, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 85550; Mature: 85550

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLDSHQHMKTPVVAARSVGTRVLRSEDPRLLTGRGEFIADIDLPRQLHVAFIRSPVAH
CCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCHHHHHHHHHCCHHH
ARITNLDLSAIRDADGVALAWSGKDVAPFCEGLVGEMAVEGCFPTTMPLLAGDEVVYVGE
HEEECCCHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEECC
PVAVVVADSRYAAEDACELIDWDFDELPAVTNVDAAAGGGPVANPQLPDNIGLNGGASFG
CEEEEEECCCCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DVSGAFEQAHQVVEGRFYTCRVSAAPMETRGVIADYEWASKALRLWSNTQMPHYLKYMLT
CHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEECHHHHHHHHHHHCCCCCHHHHHHHHH
AYLGFPEQSVEVITPDTGGGFGLKAHVYPEEMLLPLIAREVGRPVKWIEDRRENLIAGAH
HHHCCCCCCCEEECCCCCCCCCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCC
AHEQYVDIAYALDADGKITGVRTHALGDGGAYHLPPWSMAVEPWCAAVMTPTGIYDVPAV
CHHHHEEEEEEECCCCEEEEEEEEECCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCC
EYTYKAAATNKTPVGAYRGVGYMAGTFARECLADDAARALRMSPFDFRRHNVVREFPWTN
EEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHCCCCC
PQGIVYQEGSWLQTIDALEEMVDYPAFLRRQTELRKEGRYIGLGLSCFVESSGESTATSL
CCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHH
EHGLGDVYHDTATVRLNPNGTANVTIGLSAQGQGLATTMAQMAADTLGIKVEDVSVQTAR
HHCCCHHCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCEEEEECEEEECC
STSHAYGSGTLGSRGAVVAGGAVSRAADVVREKVRQVAAHMLEASTDDIELVDGLASIKG
CCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
ISDASLSIADVATAIYFDLDSWPEDFEPTLEATQAYDPSQAMFSNGGHAIMVELDAETGF
CCCCCCHHHHHHEEEEEECCCCCCCCCHHHHHHHCCCCCHHHHCCCCCEEEEEECCCCCE
VRFEKIFSVEDCGTVINPNIVEGQIRGGVIQGIGASVFEELAYDESGQILTTTFLDYGLP
EEHHHHCCHHHCCCCCCCCEEEECCCCCHHHCCCHHHHHHHHCCCCCCEEEEEEHHCCCC
TMDVAPPFEINHLETPSSHSASGVKGMGESGLIAAPAAVLNAVNDALSPFGVVLRDLPLT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCC
PEKVLGAMSGAKVATGLAERS
HHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MKKLDSHQHMKTPVVAARSVGTRVLRSEDPRLLTGRGEFIADIDLPRQLHVAFIRSPVAH
CCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCHHHHHHHHHCCHHH
ARITNLDLSAIRDADGVALAWSGKDVAPFCEGLVGEMAVEGCFPTTMPLLAGDEVVYVGE
HEEECCCHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEECC
PVAVVVADSRYAAEDACELIDWDFDELPAVTNVDAAAGGGPVANPQLPDNIGLNGGASFG
CEEEEEECCCCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DVSGAFEQAHQVVEGRFYTCRVSAAPMETRGVIADYEWASKALRLWSNTQMPHYLKYMLT
CHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEECHHHHHHHHHHHCCCCCHHHHHHHHH
AYLGFPEQSVEVITPDTGGGFGLKAHVYPEEMLLPLIAREVGRPVKWIEDRRENLIAGAH
HHHCCCCCCCEEECCCCCCCCCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCC
AHEQYVDIAYALDADGKITGVRTHALGDGGAYHLPPWSMAVEPWCAAVMTPTGIYDVPAV
CHHHHEEEEEEECCCCEEEEEEEEECCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCC
EYTYKAAATNKTPVGAYRGVGYMAGTFARECLADDAARALRMSPFDFRRHNVVREFPWTN
EEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHCCCCC
PQGIVYQEGSWLQTIDALEEMVDYPAFLRRQTELRKEGRYIGLGLSCFVESSGESTATSL
CCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHH
EHGLGDVYHDTATVRLNPNGTANVTIGLSAQGQGLATTMAQMAADTLGIKVEDVSVQTAR
HHCCCHHCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCEEEEECEEEECC
STSHAYGSGTLGSRGAVVAGGAVSRAADVVREKVRQVAAHMLEASTDDIELVDGLASIKG
CCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
ISDASLSIADVATAIYFDLDSWPEDFEPTLEATQAYDPSQAMFSNGGHAIMVELDAETGF
CCCCCCHHHHHHEEEEEECCCCCCCCCHHHHHHHCCCCCHHHHCCCCCEEEEEECCCCCE
VRFEKIFSVEDCGTVINPNIVEGQIRGGVIQGIGASVFEELAYDESGQILTTTFLDYGLP
EEHHHHCCHHHCCCCCCCCEEEECCCCCHHHCCCHHHHHHHHCCCCCCEEEEEEHHCCCC
TMDVAPPFEINHLETPSSHSASGVKGMGESGLIAAPAAVLNAVNDALSPFGVVLRDLPLT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCC
PEKVLGAMSGAKVATGLAERS
HHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]