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The map label for this gene is coxS [H]

Identifier: 119714854

GI number: 119714854

Start: 628127

End: 628633

Strand: Direct

Name: coxS [H]

Synonym: Noca_0595

Alternate gene names: 119714854

Gene position: 628127-628633 (Clockwise)

Preceding gene: 119714853

Following gene: 119714855

Centisome position: 12.6

GC content: 63.51

Gene sequence:

>507_bases
GTGTCCACGACCCCCGAAGAGCGTTTGGACGTCTCGATGACGATCAACGGGAGCCGCTACCGCGCTACGGTTGAGGCACG
CCGGACGCTGGCCGACTTCATCCGTGAGGATGCGCAGCTTCCAGGCACTAAGCTTGGCTGCGAGCACGGTGTGTGCGGAG
CATGCACGGTACTGCTCGACGATCTGCCGGCGCGTTCCTGCCTCACCCTCGCGGTGCAGGCGGAAGGCCGTCAGATCCGG
ACCGTTGAGAGCCTTGCCGATGGCCAGGAACTGAACCACCTCCAACGTGCGTTCCGCGAGCAGCACGGCCTTCAGTGTGG
ATTCTGCACGGCTGGCTTCCTGATGACGGCGACTGCGTTGCTCGAGGAGAACGCGACCCCGACACGGGAGGAGATCGTAG
AGACGATGTCGGGTTCGCTATGTCGATGCACGGGATACCAGACCATCATCTCTGCCATCGAACAAGCGGCGGCCGAGGGT
CAGAGCGACACGGAGGACGACCAGTGA

Upstream 100 bases:

>100_bases
GACCCGATCTCGGATATTCACGGCAACAGCGAGTATCGCCGGAAGCTGGTGGCCTCACTCGTACGACGTGCCGTGATCGA
ACTCATGAACGGAGCCTGAC

Downstream 100 bases:

>100_bases
AGAAGCTCGACAGTCACCAGCACATGAAGACGCCGGTCGTCGCTGCTCGGTCGGTCGGGACCCGAGTGCTGCGGTCTGAA
GACCCGCGGTTGCTCACCGG

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MSTTPEERLDVSMTINGSRYRATVEARRTLADFIREDAQLPGTKLGCEHGVCGACTVLLDDLPARSCLTLAVQAEGRQIR
TVESLADGQELNHLQRAFREQHGLQCGFCTAGFLMTATALLEENATPTREEIVETMSGSLCRCTGYQTIISAIEQAAAEG
QSDTEDDQ

Sequences:

>Translated_168_residues
MSTTPEERLDVSMTINGSRYRATVEARRTLADFIREDAQLPGTKLGCEHGVCGACTVLLDDLPARSCLTLAVQAEGRQIR
TVESLADGQELNHLQRAFREQHGLQCGFCTAGFLMTATALLEENATPTREEIVETMSGSLCRCTGYQTIISAIEQAAAEG
QSDTEDDQ
>Mature_167_residues
STTPEERLDVSMTINGSRYRATVEARRTLADFIREDAQLPGTKLGCEHGVCGACTVLLDDLPARSCLTLAVQAEGRQIRT
VESLADGQELNHLQRAFREQHGLQCGFCTAGFLMTATALLEENATPTREEIVETMSGSLCRCTGYQTIISAIEQAAAEGQ
SDTEDDQ

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=91, Percent_Identity=38.4615384615385, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI91823271, Length=155, Percent_Identity=35.4838709677419, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1786480, Length=176, Percent_Identity=40.3409090909091, Blast_Score=130, Evalue=3e-32,
Organism=Escherichia coli, GI1789232, Length=149, Percent_Identity=42.2818791946309, Blast_Score=117, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17540638, Length=156, Percent_Identity=37.8205128205128, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=37.012987012987, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=146, Percent_Identity=37.6712328767123, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24647199, Length=137, Percent_Identity=38.6861313868613, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17737937, Length=142, Percent_Identity=38.0281690140845, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24647201, Length=168, Percent_Identity=33.9285714285714, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24647193, Length=162, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647195, Length=166, Percent_Identity=30.7228915662651, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647197, Length=166, Percent_Identity=30.7228915662651, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 18259; Mature: 18127

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTPEERLDVSMTINGSRYRATVEARRTLADFIREDAQLPGTKLGCEHGVCGACTVLLD
CCCCCCHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
DLPARSCLTLAVQAEGRQIRTVESLADGQELNHLQRAFREQHGLQCGFCTAGFLMTATAL
CCCCHHHHEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHH
LEENATPTREEIVETMSGSLCRCTGYQTIISAIEQAAAEGQSDTEDDQ
HHCCCCCCHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
STTPEERLDVSMTINGSRYRATVEARRTLADFIREDAQLPGTKLGCEHGVCGACTVLLD
CCCCCHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
DLPARSCLTLAVQAEGRQIRTVESLADGQELNHLQRAFREQHGLQCGFCTAGFLMTATAL
CCCCHHHHEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHH
LEENATPTREEIVETMSGSLCRCTGYQTIISAIEQAAAEGQSDTEDDQ
HHCCCCCCHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]