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The map label for this gene is mtnU [H]

Identifier: 119714856

GI number: 119714856

Start: 631032

End: 631874

Strand: Direct

Name: mtnU [H]

Synonym: Noca_0597

Alternate gene names: 119714856

Gene position: 631032-631874 (Clockwise)

Preceding gene: 119714855

Following gene: 119714860

Centisome position: 12.66

GC content: 65.95

Gene sequence:

>843_bases
GTGACCAGCGGGGACGGCTCGCGCACGAATCGTCTGCGCGTTGCCCTGCTTCAGGTCGCTTATGGCGACGACGAGAGTCT
GTCCGATCGGGTTCAGCGAGTCAGTCAATGGATCCGCGAGGTCGGACCCGCAGACCTGGTGGTGCTCCCGGAGCTCTGGG
CGCACGGCGGCTTCGCATCCACGACGTGGCGGGCGACAGCGGAGCTCATGAACGGACCGACCATCGCGCAGATGGCCTCG
GTTGCCCGCGAGGTCGGTGTCTGGCTGCACGCGGGATCCATCATTGAGCGAGCAGAGGACGGCGCCGATCGCGGTGCCGA
GAGACGCGGACTGTGGAACACTTCTGTGCTGATCTCTCCGCAGGGCACCGTCCACAAGACGTACCGGAAGATCCACCGCT
TCGGCTTCGGCGACGGTGAACCGCGCGTTTTGGAAGCCGGCACGGACCTCGCTGTTGCCGAGCTGGTGCACGATACGGGT
GCGAGTCGCGTCGGCATGGCGACCTGCTATGACCTCCGGTTCCCGGAACTCTTCCGCCGGCTCGGCGATCTCGGTGCCGA
CGTGATCGTGCTTCCGGCGGCGTGGCCGATGCGCAGAGTGGAGCACTGGCGGTTACTCGGACGGGCGAGAGCCTTGGAGA
ACCAAGCCTGGGTGCTCCAGTGCAACACCGCCGGCACGCACAGTGGGCTGGATATGGGAGGCCATTCCCAGGTCGTCGCC
CCTACCGGTGAAGTCGTCGCCGAGCTGGGGAGCGATGAGGACGTCCTGCTCACCGACATCGATCTGAACCTCGTCGCTTC
TGTCAGAGCGGACTTTCCCGTCCTGGCCGACCGCAGGATCTAG

Upstream 100 bases:

>100_bases
CACCATTCGGCGTGGTGTTGCGCGACCTGCCACTGACGCCTGAGAAGGTGCTTGGTGCCATGTCTGGAGCGAAGGTAGCG
ACCGGTTTGGCAGAGCGGTC

Downstream 100 bases:

>100_bases
ACATACGGTTGCTCAGCCCGGCGGCCGGAAGTAGTAGTACTGACTGATTGACCCGTGCTGACCTGCGCAAACGTCGACGG
CATTCGACAGTCTGTGCCAC

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTSGDGSRTNRLRVALLQVAYGDDESLSDRVQRVSQWIREVGPADLVVLPELWAHGGFASTTWRATAELMNGPTIAQMAS
VAREVGVWLHAGSIIERAEDGADRGAERRGLWNTSVLISPQGTVHKTYRKIHRFGFGDGEPRVLEAGTDLAVAELVHDTG
ASRVGMATCYDLRFPELFRRLGDLGADVIVLPAAWPMRRVEHWRLLGRARALENQAWVLQCNTAGTHSGLDMGGHSQVVA
PTGEVVAELGSDEDVLLTDIDLNLVASVRADFPVLADRRI

Sequences:

>Translated_280_residues
MTSGDGSRTNRLRVALLQVAYGDDESLSDRVQRVSQWIREVGPADLVVLPELWAHGGFASTTWRATAELMNGPTIAQMAS
VAREVGVWLHAGSIIERAEDGADRGAERRGLWNTSVLISPQGTVHKTYRKIHRFGFGDGEPRVLEAGTDLAVAELVHDTG
ASRVGMATCYDLRFPELFRRLGDLGADVIVLPAAWPMRRVEHWRLLGRARALENQAWVLQCNTAGTHSGLDMGGHSQVVA
PTGEVVAELGSDEDVLLTDIDLNLVASVRADFPVLADRRI
>Mature_279_residues
TSGDGSRTNRLRVALLQVAYGDDESLSDRVQRVSQWIREVGPADLVVLPELWAHGGFASTTWRATAELMNGPTIAQMASV
AREVGVWLHAGSIIERAEDGADRGAERRGLWNTSVLISPQGTVHKTYRKIHRFGFGDGEPRVLEAGTDLAVAELVHDTGA
SRVGMATCYDLRFPELFRRLGDLGADVIVLPAAWPMRRVEHWRLLGRARALENQAWVLQCNTAGTHSGLDMGGHSQVVAP
TGEVVAELGSDEDVLLTDIDLNLVASVRADFPVLADRRI

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=278, Percent_Identity=33.0935251798561, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI297632348, Length=273, Percent_Identity=31.5018315018315, Blast_Score=120, Evalue=9e-28,
Organism=Homo sapiens, GI297632350, Length=273, Percent_Identity=31.5018315018315, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI5031947, Length=273, Percent_Identity=31.5018315018315, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI297632346, Length=187, Percent_Identity=28.8770053475936, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786412, Length=236, Percent_Identity=33.4745762711864, Blast_Score=94, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17556280, Length=278, Percent_Identity=30.5755395683453, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323383, Length=292, Percent_Identity=28.0821917808219, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322335, Length=309, Percent_Identity=26.537216828479, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21355835, Length=283, Percent_Identity=30.3886925795053, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI17933642, Length=271, Percent_Identity=29.8892988929889, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30536; Mature: 30405

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGDGSRTNRLRVALLQVAYGDDESLSDRVQRVSQWIREVGPADLVVLPELWAHGGFAS
CCCCCCCCCHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHCCCCCC
TTWRATAELMNGPTIAQMASVAREVGVWLHAGSIIERAEDGADRGAERRGLWNTSVLISP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHCCHHHCCCCCCEEEECC
QGTVHKTYRKIHRFGFGDGEPRVLEAGTDLAVAELVHDTGASRVGMATCYDLRFPELFRR
CCHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCHHHEECCCHHHHHHH
LGDLGADVIVLPAAWPMRRVEHWRLLGRARALENQAWVLQCNTAGTHSGLDMGGHSQVVA
HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEC
PTGEVVAELGSDEDVLLTDIDLNLVASVRADFPVLADRRI
CCHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TSGDGSRTNRLRVALLQVAYGDDESLSDRVQRVSQWIREVGPADLVVLPELWAHGGFAS
CCCCCCCCHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHCCCCCC
TTWRATAELMNGPTIAQMASVAREVGVWLHAGSIIERAEDGADRGAERRGLWNTSVLISP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHCCHHHCCCCCCEEEECC
QGTVHKTYRKIHRFGFGDGEPRVLEAGTDLAVAELVHDTGASRVGMATCYDLRFPELFRR
CCHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCHHHEECCCHHHHHHH
LGDLGADVIVLPAAWPMRRVEHWRLLGRARALENQAWVLQCNTAGTHSGLDMGGHSQVVA
HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEC
PTGEVVAELGSDEDVLLTDIDLNLVASVRADFPVLADRRI
CCHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]