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The map label for this gene is dnaX [H]

Identifier: 119714583

GI number: 119714583

Start: 340151

End: 342187

Strand: Direct

Name: dnaX [H]

Synonym: Noca_0317

Alternate gene names: 119714583

Gene position: 340151-342187 (Clockwise)

Preceding gene: 119714581

Following gene: 119714584

Centisome position: 6.82

GC content: 75.5

Gene sequence:

>2037_bases
GTGGAGTCACCCCTCGCGCTGTACCGCCGCTACCGGCCCGAGACCTTCGCGGAGGTCATCGGGCAGGCCCACGTGACGGA
GCCGCTGCGGGTGGCGCTGGCCAACAACCGGGTCAACCACGCCTACCTGTTCTCCGGACCGCGCGGCTGCGGGAAGACCA
CCTCGGCGCGGATCCTCGCCCGAGCCCTGAACTGCGACCAGGCACCGGTGGCCGACCCCTGCGGCGAGTGCGAGAGCTGC
CGCGACCTGGCCCGCGGCGGTCCGGGCTCGATCGACGTCATCGAGATCGACGCCGCCTCGCACGGTGGCGTCGACGACGC
GCGGGACCTGCGGGAGAAGGCGTTCTTCGCGCCGGTGCGCAGCAAGTACAAGGTCTACATCATCGACGAGGCCCACATGG
TCACCACGCAGGGCTTCAACGCCCTGCTCAAGCTCGTCGAGGAGCCGCCGCCGCACCTGCGCTTCATCTTCGCGACCACC
GAGCCGGACAAGGTGCTGCCGACGATCCGCTCGCGCACCCACCACTACCCGTTCCGGCTGATCCCGCCGCGGCTGCTCTC
GTCGTACCTCTCCGAGCTGTGTGCCAAGGAGGGCGTGGCCATCGATCCTGCCGCGCTCCCGCTGGTCGTGCGGGCCGGTG
GCGGATCGGCGCGCGACACCCTGTCGGTGCTCGACCAGCTGCTCGGTGGCGCCGGTCCCGCCGGCGTGACCCACGAGCTG
GCAGCCGGCCTGCTCGGCTACACGCCCGACACGCTGCTCGACGAGGTCGTCGACGCGTTCGCGGCCGGTGACGGTGCGGC
CGTGTTCCGCGTGGTCGACAAGGTCGTCGAGACCGGCCAGGACCCGCGCCGGTTCACCGAGGACCTGCTGCGCCGGCTGC
GCGACCTGGTGATCGTCGCGGCGGTGCCCGACGCGCCCGCGACCGGGCTGATCGACGTCTCGGAGGACCAGGGCGAGCGG
CTGGTGGCCCAGGCCGCCCGCTTCGGCGCCGCCGAGCTGAGCCGGGCCGCCGACATCGCCGCGACCGGGCTGACCGAGAT
GCGCGGCGCCACGGCGCCCCGCCTGCTGCTCGAGCTGCTCTGCGCCCGGATCCTGCTGCCGGGGGCCGACCACGCCACGG
ACGGGGTGCTGGCGCGGCTCGACCGGCTCGAGAAGCGGTTGACGATCACCGGCGTCCCGACCCCGACCGCCGCCGCGCCC
GCGCCCCCCGCCCAGGACCGGCCGACCCCGCCGCCCGCACGCCCGGCCGCGCCGGACCCGGCGGCCGAGCGGCCCGACCC
CGTGGCCGCGCCGCCGCCGGCTGCCCCGCCCGCGCCGCAAGCGCCTCCTGTCTCCGCGCCCACGGCTGAGCCGGAGCCGG
CCGCCGAGCCGCCCATGGCCGAGCCGCCCGTCGCCGAGCAGACATCGGCCGAACCGGCCGAGCCGCCACCGGCGAGCGCT
CCCGCGGGAGCCGCGGGTGGGTTGACGCTGGTCGACGTACGCCGGCTCTGGCCCGACATCGTCGACGCCACGAAGCTGCG
CCGGCGGGTCGCCTGGATGCACCTCACCCAGAACTGCCAGGTCGTGGGGGTCGACGGCCAGACCCTGACCCTCGGGTTCA
CCAACGCGGGTGCGCGGGACTCCTTCGTCAACGGCGGCTGCGACGAGGTGCTGCGCCAGGCCGCCATCGACGTGGTCGGT
GCCGACTGGCGGATCGAGACGATCATCGACCCCGGCGCGCGTGCGGATGTCCCGGTCGTGACCACCCCGGCGGTTCCCGC
CGCGGACCCGGCGCCCGCGCCGGAGGCCGGCCCGCCGGCCGAGGAGGCCCCGCAGCCACGGCGCACGAGCGACCCCGAGT
CGATCGCGGCCGCTCGGGAGGCGATCCAGCAGACCCGCGCCGGTGACGAGCCCCGGCCCGAGGGGCCGGACTGGGCGGCC
GCCGACGCCGACGCCCACCCCGACGACCTCGACGCCGACCAGCAGGGCATGAGCACCGCCGAGCTGCTCCAGCGCGAGCT
CGGCGCGCAGATGATCGAGGAGATCCGCCACCAGTGA

Upstream 100 bases:

>100_bases
GATCGGCGTATCGAGGCCCAGCCGCCCATCGGAGCGTCCCGCCCCGCGGCGGCCACCCACGCCGCTACCGGCTGTCGGAC
CCGGTGGTTAGGGTTCATGC

Downstream 100 bases:

>100_bases
GCCCGTACTGCCCGTGCCGACCCGTGACGACCCAGCGACCACCAGAGGTGAACCCATGAGCCAGAACCCCTTCGAAGCCC
TTGGTGGCGGAGGGTTCGAC

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MESPLALYRRYRPETFAEVIGQAHVTEPLRVALANNRVNHAYLFSGPRGCGKTTSARILARALNCDQAPVADPCGECESC
RDLARGGPGSIDVIEIDAASHGGVDDARDLREKAFFAPVRSKYKVYIIDEAHMVTTQGFNALLKLVEEPPPHLRFIFATT
EPDKVLPTIRSRTHHYPFRLIPPRLLSSYLSELCAKEGVAIDPAALPLVVRAGGGSARDTLSVLDQLLGGAGPAGVTHEL
AAGLLGYTPDTLLDEVVDAFAAGDGAAVFRVVDKVVETGQDPRRFTEDLLRRLRDLVIVAAVPDAPATGLIDVSEDQGER
LVAQAARFGAAELSRAADIAATGLTEMRGATAPRLLLELLCARILLPGADHATDGVLARLDRLEKRLTITGVPTPTAAAP
APPAQDRPTPPPARPAAPDPAAERPDPVAAPPPAAPPAPQAPPVSAPTAEPEPAAEPPMAEPPVAEQTSAEPAEPPPASA
PAGAAGGLTLVDVRRLWPDIVDATKLRRRVAWMHLTQNCQVVGVDGQTLTLGFTNAGARDSFVNGGCDEVLRQAAIDVVG
ADWRIETIIDPGARADVPVVTTPAVPAADPAPAPEAGPPAEEAPQPRRTSDPESIAAAREAIQQTRAGDEPRPEGPDWAA
ADADAHPDDLDADQQGMSTAELLQRELGAQMIEEIRHQ

Sequences:

>Translated_678_residues
MESPLALYRRYRPETFAEVIGQAHVTEPLRVALANNRVNHAYLFSGPRGCGKTTSARILARALNCDQAPVADPCGECESC
RDLARGGPGSIDVIEIDAASHGGVDDARDLREKAFFAPVRSKYKVYIIDEAHMVTTQGFNALLKLVEEPPPHLRFIFATT
EPDKVLPTIRSRTHHYPFRLIPPRLLSSYLSELCAKEGVAIDPAALPLVVRAGGGSARDTLSVLDQLLGGAGPAGVTHEL
AAGLLGYTPDTLLDEVVDAFAAGDGAAVFRVVDKVVETGQDPRRFTEDLLRRLRDLVIVAAVPDAPATGLIDVSEDQGER
LVAQAARFGAAELSRAADIAATGLTEMRGATAPRLLLELLCARILLPGADHATDGVLARLDRLEKRLTITGVPTPTAAAP
APPAQDRPTPPPARPAAPDPAAERPDPVAAPPPAAPPAPQAPPVSAPTAEPEPAAEPPMAEPPVAEQTSAEPAEPPPASA
PAGAAGGLTLVDVRRLWPDIVDATKLRRRVAWMHLTQNCQVVGVDGQTLTLGFTNAGARDSFVNGGCDEVLRQAAIDVVG
ADWRIETIIDPGARADVPVVTTPAVPAADPAPAPEAGPPAEEAPQPRRTSDPESIAAAREAIQQTRAGDEPRPEGPDWAA
ADADAHPDDLDADQQGMSTAELLQRELGAQMIEEIRHQ
>Mature_678_residues
MESPLALYRRYRPETFAEVIGQAHVTEPLRVALANNRVNHAYLFSGPRGCGKTTSARILARALNCDQAPVADPCGECESC
RDLARGGPGSIDVIEIDAASHGGVDDARDLREKAFFAPVRSKYKVYIIDEAHMVTTQGFNALLKLVEEPPPHLRFIFATT
EPDKVLPTIRSRTHHYPFRLIPPRLLSSYLSELCAKEGVAIDPAALPLVVRAGGGSARDTLSVLDQLLGGAGPAGVTHEL
AAGLLGYTPDTLLDEVVDAFAAGDGAAVFRVVDKVVETGQDPRRFTEDLLRRLRDLVIVAAVPDAPATGLIDVSEDQGER
LVAQAARFGAAELSRAADIAATGLTEMRGATAPRLLLELLCARILLPGADHATDGVLARLDRLEKRLTITGVPTPTAAAP
APPAQDRPTPPPARPAAPDPAAERPDPVAAPPPAAPPAPQAPPVSAPTAEPEPAAEPPMAEPPVAEQTSAEPAEPPPASA
PAGAAGGLTLVDVRRLWPDIVDATKLRRRVAWMHLTQNCQVVGVDGQTLTLGFTNAGARDSFVNGGCDEVLRQAAIDVVG
ADWRIETIIDPGARADVPVVTTPAVPAADPAPAPEAGPPAEEAPQPRRTSDPESIAAAREAIQQTRAGDEPRPEGPDWAA
ADADAHPDDLDADQQGMSTAELLQRELGAQMIEEIRHQ

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=268, Percent_Identity=23.134328358209, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI194306571, Length=271, Percent_Identity=22.8782287822878, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI194306567, Length=271, Percent_Identity=22.8782287822878, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI4506491, Length=311, Percent_Identity=23.1511254019293, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI31881687, Length=311, Percent_Identity=23.1511254019293, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1786676, Length=299, Percent_Identity=39.7993311036789, Blast_Score=234, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17541988, Length=341, Percent_Identity=26.6862170087977, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324039, Length=217, Percent_Identity=27.6497695852535, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322528, Length=287, Percent_Identity=23.6933797909408, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 71449; Mature: 71449

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESPLALYRRYRPETFAEVIGQAHVTEPLRVALANNRVNHAYLFSGPRGCGKTTSARILA
CCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHH
RALNCDQAPVADPCGECESCRDLARGGPGSIDVIEIDAASHGGVDDARDLREKAFFAPVR
HHHCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHC
SKYKVYIIDEAHMVTTQGFNALLKLVEEPPPHLRFIFATTEPDKVLPTIRSRTHHYPFRL
CCEEEEEEECCCEEHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCEE
IPPRLLSSYLSELCAKEGVAIDPAALPLVVRAGGGSARDTLSVLDQLLGGAGPAGVTHEL
CCHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHH
AAGLLGYTPDTLLDEVVDAFAAGDGAAVFRVVDKVVETGQDPRRFTEDLLRRLRDLVIVA
HHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEE
AVPDAPATGLIDVSEDQGERLVAQAARFGAAELSRAADIAATGLTEMRGATAPRLLLELL
ECCCCCCCCEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
CARILLPGADHATDGVLARLDRLEKRLTITGVPTPTAAAPAPPAQDRPTPPPARPAAPDP
HHHHHCCCCCCCHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAERPDPVAAPPPAAPPAPQAPPVSAPTAEPEPAAEPPMAEPPVAEQTSAEPAEPPPASA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAGAAGGLTLVDVRRLWPDIVDATKLRRRVAWMHLTQNCQVVGVDGQTLTLGFTNAGARD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCC
SFVNGGCDEVLRQAAIDVVGADWRIETIIDPGARADVPVVTTPAVPAADPAPAPEAGPPA
CCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCH
EEAPQPRRTSDPESIAAAREAIQQTRAGDEPRPEGPDWAAADADAHPDDLDADQQGMSTA
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHH
ELLQRELGAQMIEEIRHQ
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MESPLALYRRYRPETFAEVIGQAHVTEPLRVALANNRVNHAYLFSGPRGCGKTTSARILA
CCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHH
RALNCDQAPVADPCGECESCRDLARGGPGSIDVIEIDAASHGGVDDARDLREKAFFAPVR
HHHCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHC
SKYKVYIIDEAHMVTTQGFNALLKLVEEPPPHLRFIFATTEPDKVLPTIRSRTHHYPFRL
CCEEEEEEECCCEEHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCEE
IPPRLLSSYLSELCAKEGVAIDPAALPLVVRAGGGSARDTLSVLDQLLGGAGPAGVTHEL
CCHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHH
AAGLLGYTPDTLLDEVVDAFAAGDGAAVFRVVDKVVETGQDPRRFTEDLLRRLRDLVIVA
HHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEE
AVPDAPATGLIDVSEDQGERLVAQAARFGAAELSRAADIAATGLTEMRGATAPRLLLELL
ECCCCCCCCEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
CARILLPGADHATDGVLARLDRLEKRLTITGVPTPTAAAPAPPAQDRPTPPPARPAAPDP
HHHHHCCCCCCCHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAERPDPVAAPPPAAPPAPQAPPVSAPTAEPEPAAEPPMAEPPVAEQTSAEPAEPPPASA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAGAAGGLTLVDVRRLWPDIVDATKLRRRVAWMHLTQNCQVVGVDGQTLTLGFTNAGARD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCC
SFVNGGCDEVLRQAAIDVVGADWRIETIIDPGARADVPVVTTPAVPAADPAPAPEAGPPA
CCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCH
EEAPQPRRTSDPESIAAAREAIQQTRAGDEPRPEGPDWAAADADAHPDDLDADQQGMSTA
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHH
ELLQRELGAQMIEEIRHQ
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]