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The map label for this gene is ifcA [H]

Identifier: 119714470

GI number: 119714470

Start: 217732

End: 219144

Strand: Reverse

Name: ifcA [H]

Synonym: Noca_0203

Alternate gene names: 119714470

Gene position: 219144-217732 (Counterclockwise)

Preceding gene: 119714471

Following gene: 119714469

Centisome position: 4.4

GC content: 73.89

Gene sequence:

>1413_bases
GTGATCCCCGGCCTGCCGATCGAGGGCGAGCTGCCCGACCGGGTCGGTGTACTCGTGCTCGGCAGCGGGCTCGCCGGGTG
CGCCGCCCTGCTCGCCGCGGCTGAGGCCGGTCAGTACGCCGTGCTCCTGGAGAAGACCGGCGCCATCGGCGGCAGCACGG
TCCGCTCCGCCGGGCTCTCCGCGTTCGCGGGCACTCCGGAGCAGGTGGCCCAGGGGATCGGCGACTCGGTGGAGCTGCTC
AAGAAGGACCTGATGGAGACCGGGCGGCACGTCTGCGACGAGGCGCTGGTCGACCTGTACTGCGCGCACCAGCTCGAGAC
CTACGAGTGGCTGACCGGGCACGGCGTCCGGTACGGCGAGGTGCACGCCGCGTCCGGCCAGTCGGTCCCGCGCTCGCACC
CCACCGACACCACCGGGATGCTGGTCACCCTGCTCAAGGCGGCCGGCCGGCTGGGTGCCCGGATCCTCCTCGACACGGCC
GCCGAGCGGCTGGTCCGCGAGGGCGGCCAAGTGATCGGCGTCGACGTGCGCACCGCGGACGGCAGCCGCCGGCGGATCCT
CGCCGACGCGGTCGTGCTCGCCACCGGCGGCTTCGCGCGCAGCCCGGAGCTGCTCACCCGGTTCGCGCCGCAGATGGCGA
ACGCGCTCACCGCGGGCGGCGACGGGTGCACCGGCGACGGCCTGCTGATGGGCTGGCAGCTCGGGGCGGGGGTCGTGGAC
ACGCCGTACGTCAAGGGGACCTACGGGATCTTCCACGAGGCCCACCCCGACGAGGACGGCACCGGCATCCTCGCGGTCTA
CAAGGGCGCGATCGCGGTCAACCGCGAGGGACGCCGCTTCGTCGACGAGTCCCTGCCCTACAAGGAGATCGGCGACGCGG
CCCTGGCCCAGCCGGGCGTCACGACCTGGCAGGTCTTCGACGCCGGCGTGATGGCCCAGAGCAACGACGAGGTGCCGATC
TACGAGTTCGCGGGCCGCGACCGGGCCGGCATGCTGCTCAAGGCCGACACGGTCGAGGGGCTCGAGGCGCTGGTGGGCCT
CCCGGACGGCTCACTCGTCGCGACCGTCGCCGACTACAACGCCCGGATCGCCGATGGCCGGCCCGACCCGCTGGGCCGCG
CCCACCTCTCCGGCGGCGTGGATACGCCGACCCCGCTCGACCGGCCCCCGTTCTACGCCCACCCGTCGCGGACCGTCGTG
CTCGCGACGTACTGCGGCCTCACGGTGGACACCCGGCTGCGCGTGCTCGACGTGTTCGGGGAGCCGATCGAGCGCCTCTA
CGCCGCGGGCGAGGTGATCGGCGGGTTCCACGGCGGCGGCTACATGACCGGCACGTCGATCGGCAAGGCCGGCATCTTCG
GCCGCCTGGCCGGGCAGCACGCCGCGGCCGAGGAGAGCGAGCTGACATGGTGA

Upstream 100 bases:

>100_bases
TGGCGACCTGGAGCGAGCGTCAGTCGCTGTTCCACCTCCCGGCGTTCACCGCCGCCGAGGCCTACTTCGACCAGCCCCTC
GACGTGCTTCGGAGCGAGCG

Downstream 100 bases:

>100_bases
GCCCCTTCGACCTCACCGGTCAGGTCGCGCTCGTGGTCGGCGGCGCCGGCGGCCTGGGAGCGCGCGCCGCCACGGCGCTC
GCCGCGCAGGGCGCGACCGT

Product: fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein

Products: NA

Alternate protein names: Fe(3+)-induced flavocytochrome C3; Ifc3; Iron(III)-induced flavocytochrome C3 [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MIPGLPIEGELPDRVGVLVLGSGLAGCAALLAAAEAGQYAVLLEKTGAIGGSTVRSAGLSAFAGTPEQVAQGIGDSVELL
KKDLMETGRHVCDEALVDLYCAHQLETYEWLTGHGVRYGEVHAASGQSVPRSHPTDTTGMLVTLLKAAGRLGARILLDTA
AERLVREGGQVIGVDVRTADGSRRRILADAVVLATGGFARSPELLTRFAPQMANALTAGGDGCTGDGLLMGWQLGAGVVD
TPYVKGTYGIFHEAHPDEDGTGILAVYKGAIAVNREGRRFVDESLPYKEIGDAALAQPGVTTWQVFDAGVMAQSNDEVPI
YEFAGRDRAGMLLKADTVEGLEALVGLPDGSLVATVADYNARIADGRPDPLGRAHLSGGVDTPTPLDRPPFYAHPSRTVV
LATYCGLTVDTRLRVLDVFGEPIERLYAAGEVIGGFHGGGYMTGTSIGKAGIFGRLAGQHAAAEESELTW

Sequences:

>Translated_470_residues
MIPGLPIEGELPDRVGVLVLGSGLAGCAALLAAAEAGQYAVLLEKTGAIGGSTVRSAGLSAFAGTPEQVAQGIGDSVELL
KKDLMETGRHVCDEALVDLYCAHQLETYEWLTGHGVRYGEVHAASGQSVPRSHPTDTTGMLVTLLKAAGRLGARILLDTA
AERLVREGGQVIGVDVRTADGSRRRILADAVVLATGGFARSPELLTRFAPQMANALTAGGDGCTGDGLLMGWQLGAGVVD
TPYVKGTYGIFHEAHPDEDGTGILAVYKGAIAVNREGRRFVDESLPYKEIGDAALAQPGVTTWQVFDAGVMAQSNDEVPI
YEFAGRDRAGMLLKADTVEGLEALVGLPDGSLVATVADYNARIADGRPDPLGRAHLSGGVDTPTPLDRPPFYAHPSRTVV
LATYCGLTVDTRLRVLDVFGEPIERLYAAGEVIGGFHGGGYMTGTSIGKAGIFGRLAGQHAAAEESELTW
>Mature_470_residues
MIPGLPIEGELPDRVGVLVLGSGLAGCAALLAAAEAGQYAVLLEKTGAIGGSTVRSAGLSAFAGTPEQVAQGIGDSVELL
KKDLMETGRHVCDEALVDLYCAHQLETYEWLTGHGVRYGEVHAASGQSVPRSHPTDTTGMLVTLLKAAGRLGARILLDTA
AERLVREGGQVIGVDVRTADGSRRRILADAVVLATGGFARSPELLTRFAPQMANALTAGGDGCTGDGLLMGWQLGAGVVD
TPYVKGTYGIFHEAHPDEDGTGILAVYKGAIAVNREGRRFVDESLPYKEIGDAALAQPGVTTWQVFDAGVMAQSNDEVPI
YEFAGRDRAGMLLKADTVEGLEALVGLPDGSLVATVADYNARIADGRPDPLGRAHLSGGVDTPTPLDRPPFYAHPSRTVV
LATYCGLTVDTRLRVLDVFGEPIERLYAAGEVIGGFHGGGYMTGTSIGKAGIFGRLAGQHAAAEESELTW

Specific function: Catalyzes unidirectional fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71986328, Length=472, Percent_Identity=29.8728813559322, Blast_Score=168, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6320788, Length=476, Percent_Identity=25.6302521008403, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322511, Length=476, Percent_Identity=23.9495798319328, Blast_Score=91, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 49028; Mature: 49028

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPGLPIEGELPDRVGVLVLGSGLAGCAALLAAAEAGQYAVLLEKTGAIGGSTVRSAGLS
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHCCCH
AFAGTPEQVAQGIGDSVELLKKDLMETGRHVCDEALVDLYCAHQLETYEWLTGHGVRYGE
HHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECE
VHAASGQSVPRSHPTDTTGMLVTLLKAAGRLGARILLDTAAERLVREGGQVIGVDVRTAD
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEEECC
GSRRRILADAVVLATGGFARSPELLTRFAPQMANALTAGGDGCTGDGLLMGWQLGAGVVD
CCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
TPYVKGTYGIFHEAHPDEDGTGILAVYKGAIAVNREGRRFVDESLPYKEIGDAALAQPGV
CCCCCCCHHHCCCCCCCCCCCEEEEEEECEEEECCCCCHHHHHCCCHHHHCCHHHCCCCC
TTWQVFDAGVMAQSNDEVPIYEFAGRDRAGMLLKADTVEGLEALVGLPDGSLVATVADYN
CEEEEECCCEEECCCCCCCEEEECCCCCCCEEEEECHHHHHHHHHCCCCCCEEEEEECCC
ARIADGRPDPLGRAHLSGGVDTPTPLDRPPFYAHPSRTVVLATYCGLTVDTRLRVLDVFG
CEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEHHHHHHHHHHC
EPIERLYAAGEVIGGFHGGGYMTGTSIGKAGIFGRLAGQHAAAEESELTW
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MIPGLPIEGELPDRVGVLVLGSGLAGCAALLAAAEAGQYAVLLEKTGAIGGSTVRSAGLS
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHCCCH
AFAGTPEQVAQGIGDSVELLKKDLMETGRHVCDEALVDLYCAHQLETYEWLTGHGVRYGE
HHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECE
VHAASGQSVPRSHPTDTTGMLVTLLKAAGRLGARILLDTAAERLVREGGQVIGVDVRTAD
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEEECC
GSRRRILADAVVLATGGFARSPELLTRFAPQMANALTAGGDGCTGDGLLMGWQLGAGVVD
CCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
TPYVKGTYGIFHEAHPDEDGTGILAVYKGAIAVNREGRRFVDESLPYKEIGDAALAQPGV
CCCCCCCHHHCCCCCCCCCCCEEEEEEECEEEECCCCCHHHHHCCCHHHHCCHHHCCCCC
TTWQVFDAGVMAQSNDEVPIYEFAGRDRAGMLLKADTVEGLEALVGLPDGSLVATVADYN
CEEEEECCCEEECCCCCCCEEEECCCCCCCEEEEECHHHHHHHHHCCCCCCEEEEEECCC
ARIADGRPDPLGRAHLSGGVDTPTPLDRPPFYAHPSRTVVLATYCGLTVDTRLRVLDVFG
CEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEHHHHHHHHHHC
EPIERLYAAGEVIGGFHGGGYMTGTSIGKAGIFGRLAGQHAAAEESELTW
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10455032; 10581549 [H]