BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is fabG [H]

Identifier: 119714469

GI number: 119714469

Start: 217019

End: 217738

Strand: Reverse

Name: fabG [H]

Synonym: Noca_0202

Alternate gene names: 119714469

Gene position: 217738-217019 (Counterclockwise)

Preceding gene: 119714470

Following gene: 119714468

Centisome position: 4.37

GC content: 75.0

Gene sequence:

>720_bases
ATGGTGAGCCCCTTCGACCTCACCGGTCAGGTCGCGCTCGTGGTCGGCGGCGCCGGCGGCCTGGGAGCGCGCGCCGCCAC
GGCGCTCGCCGCGCAGGGCGCGACCGTCGAGGTCGCCGACCTCGCCGGCGCCGACCGGCATGTCGACGTCACCGACGAGG
CGTCGGTCGCCGGCCTGGTCGCCGACGTCGTCGCCGCGCACGGTCGGCTCGACGTCGTGGTCAACGCCGCCGGCGTGATG
CTGCGCAAGGCGTACGACGAGACCACGGTCGAGGAGTTCGAGCGCGTGGTCCGGGTGAACCTCACCGGCACCTGGCTGGT
GGGCCGCGAGGCCGGCAAGGCGATGACGCCGCAGCGGTCCGGGCGCATCGTCAACCTCACGACGGTCTACGCCGAGCGGG
TCGGACCGGTGCCGGAGTCGGCGTACTACGCCTCGAAGGCCGGGGTCGCCAACGTGACGCGGGCGCTCGCGGCCGAGCTC
GGCCCGCACGGCATCACCGTCAACTGCCTGGCCCCCGGCGTGTTCTACCCGACCCCGATGACCGCGCCCCTCGGCGCCGA
CCCCGATCGGCTCGCCTGGTTCGCGGACCGCACCATGCTCGGCCGGCTCGGCGACCCCGCCGCCGACCTGGACGGGCCCC
TGCTCCTGCTGGCCTCACCGGCCTCGTCGTACGTCACCGGCCAGGTGGTCTACGTCGACGGCGGCTGGTCGGCCTGGTGA

Upstream 100 bases:

>100_bases
TCCACGGCGGCGGCTACATGACCGGCACGTCGATCGGCAAGGCCGGCATCTTCGGCCGCCTGGCCGGGCAGCACGCCGCG
GCCGAGGAGAGCGAGCTGAC

Downstream 100 bases:

>100_bases
CCACATCCCCGACGACGAAGGAACCCCGATGACCGACAACCGCAAGGCCCTCCTGCTCCTGGACTACCAGGTCGCGCTGT
GCGAGGAGGGCCCGCACCTG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MVSPFDLTGQVALVVGGAGGLGARAATALAAQGATVEVADLAGADRHVDVTDEASVAGLVADVVAAHGRLDVVVNAAGVM
LRKAYDETTVEEFERVVRVNLTGTWLVGREAGKAMTPQRSGRIVNLTTVYAERVGPVPESAYYASKAGVANVTRALAAEL
GPHGITVNCLAPGVFYPTPMTAPLGADPDRLAWFADRTMLGRLGDPAADLDGPLLLLASPASSYVTGQVVYVDGGWSAW

Sequences:

>Translated_239_residues
MVSPFDLTGQVALVVGGAGGLGARAATALAAQGATVEVADLAGADRHVDVTDEASVAGLVADVVAAHGRLDVVVNAAGVM
LRKAYDETTVEEFERVVRVNLTGTWLVGREAGKAMTPQRSGRIVNLTTVYAERVGPVPESAYYASKAGVANVTRALAAEL
GPHGITVNCLAPGVFYPTPMTAPLGADPDRLAWFADRTMLGRLGDPAADLDGPLLLLASPASSYVTGQVVYVDGGWSAW
>Mature_239_residues
MVSPFDLTGQVALVVGGAGGLGARAATALAAQGATVEVADLAGADRHVDVTDEASVAGLVADVVAAHGRLDVVVNAAGVM
LRKAYDETTVEEFERVVRVNLTGTWLVGREAGKAMTPQRSGRIVNLTTVYAERVGPVPESAYYASKAGVANVTRALAAEL
GPHGITVNCLAPGVFYPTPMTAPLGADPDRLAWFADRTMLGRLGDPAADLDGPLLLLASPASSYVTGQVVYVDGGWSAW

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=33.4630350194552, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI4758504, Length=257, Percent_Identity=34.6303501945525, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=31.8181818181818, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI19923817, Length=268, Percent_Identity=27.9850746268657, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI83715985, Length=256, Percent_Identity=32.421875, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=30.7392996108949, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=28.8617886178862, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI59889578, Length=193, Percent_Identity=33.160621761658, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4504505, Length=195, Percent_Identity=32.8205128205128, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=30.4347826086957, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI7705925, Length=240, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=29.296875, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI31542939, Length=235, Percent_Identity=28.5106382978723, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=28.5140562248996, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI20149619, Length=219, Percent_Identity=25.1141552511416, Blast_Score=64, Evalue=9e-11,
Organism=Homo sapiens, GI4503301, Length=255, Percent_Identity=27.4509803921569, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=33.7301587301587, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=33.4677419354839, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=35.6862745098039, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=31.7073170731707, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=32.3076923076923, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=30.0395256916996, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=29.5546558704453, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=33.8709677419355, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=29.9595141700405, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=28.8617886178862, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=28.6307053941909, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=30.2788844621514, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=33.7349397590361, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=30.9236947791165, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=29.6, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=33.7254901960784, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=29.6442687747036, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=28.4090909090909, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=27.1698113207547, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=192, Percent_Identity=31.25, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=28.030303030303, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=27.8195488721804, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=27.6515151515151, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=27.3408239700375, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=24.8091603053435, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=30.7291666666667, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=26.0377358490566, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=25.6505576208178, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=24.4274809160305, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=23.6641221374046, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=27.1317829457364, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=24.5283018867925, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=26.3940520446097, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=204, Percent_Identity=29.9019607843137, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=27.5092936802974, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=25.2873563218391, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=25, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=32.620320855615, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=30.2788844621514, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=36.6533864541833, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=32.5396825396825, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=32.9457364341085, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21357041, Length=198, Percent_Identity=33.8383838383838, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=29.9610894941634, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=29.9212598425197, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24644337, Length=173, Percent_Identity=35.2601156069364, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=30.7377049180328, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=26.7175572519084, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI18859837, Length=187, Percent_Identity=28.3422459893048, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24585; Mature: 24585

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSPFDLTGQVALVVGGAGGLGARAATALAAQGATVEVADLAGADRHVDVTDEASVAGLV
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEHCCCCCCCEECCCCCHHHHHHH
ADVVAAHGRLDVVVNAAGVMLRKAYDETTVEEFERVVRVNLTGTWLVGREAGKAMTPQRS
HHHHHCCCCEEEEEEHHHHHHHHHHCHHHHHHHHHEEEEECCEEEEEECCCCCCCCCCCC
GRIVNLTTVYAERVGPVPESAYYASKAGVANVTRALAAELGPHGITVNCLAPGVFYPTPM
CCEEEEEEEEHHHCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCEECCCCC
TAPLGADPDRLAWFADRTMLGRLGDPAADLDGPLLLLASPASSYVTGQVVYVDGGWSAW
CCCCCCCHHHHEEHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MVSPFDLTGQVALVVGGAGGLGARAATALAAQGATVEVADLAGADRHVDVTDEASVAGLV
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEHCCCCCCCEECCCCCHHHHHHH
ADVVAAHGRLDVVVNAAGVMLRKAYDETTVEEFERVVRVNLTGTWLVGREAGKAMTPQRS
HHHHHCCCCEEEEEEHHHHHHHHHHCHHHHHHHHHEEEEECCEEEEEECCCCCCCCCCCC
GRIVNLTTVYAERVGPVPESAYYASKAGVANVTRALAAELGPHGITVNCLAPGVFYPTPM
CCEEEEEEEEHHHCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCEECCCCC
TAPLGADPDRLAWFADRTMLGRLGDPAADLDGPLLLLASPASSYVTGQVVYVDGGWSAW
CCCCCCCHHHHEEHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]