Click here to switch to the map view.

The map label for this gene is ccdA [H]

Identifier: 119386853

GI number: 119386853

Start: 1305975

End: 1306712

Strand: Direct

Name: ccdA [H]

Synonym: Pden_4148

Alternate gene names: 119386853

Gene position: 1305975-1306712 (Clockwise)

Preceding gene: 119386849

Following gene: 119386854

Centisome position: 75.49

GC content: 67.07

Gene sequence:

>738_bases
ATGCTGGATGTCACCTATGGCGGAGCCGCGCTTGCGGGGCTGCTTTCGTTTCTGTCGCCCTGCATCCTGCCGATGGTGCC
GTTCTATCTGTCCTACATGGCCGGGGTGTCGGTGCGCGAATTGCGCGACGGCGGCACGGTGGCGCCGGGCGCGCGCGGGC
GGATGGTGCTGCGGGCCTGGGCCTTTGCGCTTGGCGTGACCACGATCTTCCTGCTGCTGGGGCTGGGCGCCACGGCGCTT
GGCAAGGCCTTCGCGCAATGGAAGGAAACCCTGTCTTGGGCGGCTGCCGGGGTGCTGATCCTGTTCGGCCTGCATTTCCT
GGGCGTGCTGCGGATCGGCCTACTTTATCGCGAGGCGCGGGTGCAGACCGGGGCCAGGCCCTCGACCCTGGCCGGCGCCT
ATGTGATGGGGCTGGCCTTCGGCTTCGGCTGGACGCCCTGCGTGGGACCGGCGCTGGCGGCGATCCTGATGGTGGCCTCG
GGCATGGGAGATCTGTGGCGCGGCGGGCTGCTGCTGGTGGTCTACGGGCTTGCGATGACCCTGCCCTTCGTGCTGGCGGC
CTTTTTCGCAGGACCGTTCCTGGGCTGGGTCGCGCGCCACCGCGCGCTGATGGGACATGTGGAAAAGGCGATGGGGGTCA
TGCTGATCCTGTTCGGCATCCTGATCGCCACCAATTCCGTGAATGTCATCGCCGACTGGATGATTCGCCACTTCGACTGG
ACAGCCACGCTTACCTGA

Upstream 100 bases:

>100_bases
CGACGGGATTGACGCCAGAATTTGAACATAGGAATATTCTAATATAATGCCGGCCACCGGGCAAGCACCGGCAGGATGGC
AGGCTGCGGGGGAGAGGCCG

Downstream 100 bases:

>100_bases
GAGGAGCCCGACCATGAAACCGATCCGTGCCCTGGCCGCCTGCCTGTTGCTGGCCGCGACACCCGCAGCCGCGGTCGAAA
CCGGCGATGACGGCCTGCAC

Product: cytochrome c biogenesis protein, transmembrane region

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MLDVTYGGAALAGLLSFLSPCILPMVPFYLSYMAGVSVRELRDGGTVAPGARGRMVLRAWAFALGVTTIFLLLGLGATAL
GKAFAQWKETLSWAAAGVLILFGLHFLGVLRIGLLYREARVQTGARPSTLAGAYVMGLAFGFGWTPCVGPALAAILMVAS
GMGDLWRGGLLLVVYGLAMTLPFVLAAFFAGPFLGWVARHRALMGHVEKAMGVMLILFGILIATNSVNVIADWMIRHFDW
TATLT

Sequences:

>Translated_245_residues
MLDVTYGGAALAGLLSFLSPCILPMVPFYLSYMAGVSVRELRDGGTVAPGARGRMVLRAWAFALGVTTIFLLLGLGATAL
GKAFAQWKETLSWAAAGVLILFGLHFLGVLRIGLLYREARVQTGARPSTLAGAYVMGLAFGFGWTPCVGPALAAILMVAS
GMGDLWRGGLLLVVYGLAMTLPFVLAAFFAGPFLGWVARHRALMGHVEKAMGVMLILFGILIATNSVNVIADWMIRHFDW
TATLT
>Mature_245_residues
MLDVTYGGAALAGLLSFLSPCILPMVPFYLSYMAGVSVRELRDGGTVAPGARGRMVLRAWAFALGVTTIFLLLGLGATAL
GKAFAQWKETLSWAAAGVLILFGLHFLGVLRIGLLYREARVQTGARPSTLAGAYVMGLAFGFGWTPCVGPALAAILMVAS
GMGDLWRGGLLLVVYGLAMTLPFVLAAFFAGPFLGWVARHRALMGHVEKAMGVMLILFGILIATNSVNVIADWMIRHFDW
TATLT

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 26055; Mature: 26055

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDVTYGGAALAGLLSFLSPCILPMVPFYLSYMAGVSVRELRDGGTVAPGARGRMVLRAW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHH
AFALGVTTIFLLLGLGATALGKAFAQWKETLSWAAAGVLILFGLHFLGVLRIGLLYREAR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQTGARPSTLAGAYVMGLAFGFGWTPCVGPALAAILMVASGMGDLWRGGLLLVVYGLAMT
HHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LPFVLAAFFAGPFLGWVARHRALMGHVEKAMGVMLILFGILIATNSVNVIADWMIRHFDW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
TATLT
CEECC
>Mature Secondary Structure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CEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]