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The map label for this gene is pyc [H]

Identifier: 119386849

GI number: 119386849

Start: 1300140

End: 1303574

Strand: Direct

Name: pyc [H]

Synonym: Pden_4144

Alternate gene names: 119386849

Gene position: 1300140-1303574 (Clockwise)

Preceding gene: 119386848

Following gene: 119386853

Centisome position: 75.15

GC content: 67.77

Gene sequence:

>3435_bases
ATGTTCCGTAAGATTCTTATTGCGAACCGTGGCGAGATTGCGATCCGCGTGATGCGGGCTGCGAACGAGCTTGGGAAGAA
GACGGTCGCGGTCTATGCCGAGGAAGACAAGCTGAGCCTGCACCGCTTCAAGGCGGACGAGGCCTACCGCATCGGCGGCG
GCCTGGGGCCGGTCGCGGCCTATCTGTCCATCCCCGAGATCATCCGGGTGGCGAAGGAATCCGGCGCCGATGCGATCCAT
CCCGGCTATGGGCTTCTGTCCGAAAACCCCGATTTCGTCGATGCCTGCACCGCAGCGGGCATCGCCTTCATCGGGCCGAG
CGCCGACACCATGCGGGCGCTTGGCGACAAGGCCAGCGCCCGGCGCGTGGCGATCCAGGCCGGCGTGCCGGTGATCCCGG
CCACCGAGGTGCTGGGCGAGGACATGGAGGCGATCAAGCGTGAGGCGGCCGAGATCGGCTATCCGCTGATGCTGAAGGCC
AGCTGGGGCGGCGGCGGGCGCGGCATGCGCCCGATCATGGGCCCCGAGGAGCTGCCCGAGAAGGTGCGCGAGGGACGGCG
CGAGGCCGAGGCCGCCTTCGGCAACGGCGAGGGCTATCTGGAAAAGATGATCCTGCGCGCCCGGCACGTCGAGGTGCAGC
TCTTGGGTGATGGGCATGGCGGGCTCTATCACCTCTACGAGCGCGACTGCACCGTGCAGCGCCGCAACCAGAAGGTCGTG
GAACGCGCCCCGGCGCCCTACCTGACCCCCGAACAGCGCGCCGAGGTCTGCGAGCTGGCGCTGAGGATCGGCCGCGCCGT
CGGCTACCGCAACGCCGGCACCGTCGAATTCCTGATGGATATGGACAGCCAGGCCTTCTACTTCATCGAGGTGAACCCGC
GCGTTCAGGTCGAGCATACCGTGACCGAGGAGGTCACCGGCATCGACATCGTGCAAAGCCAGATCCTGATCGCCGAGGGC
GCGACGCTGGCCCAGGCCACCGGCGTCGCCTCCCAGGCCGGGGTGCATCTGAACGGCCACGCCCTGCAATGCCGGGTCAC
GACCGAGGATCCGCTGAACAACTTCATCCCCGATTACGGCCGCATCACCGCCTATCGCTCGGCCACCGGCAACGGCATCC
GGCTGGACGGCGGCACCGCCTATTCCGGCGGCGTCATCACCCGCTATTACGACAGCCTGCTGGTCAAGGTCACGGCGCAT
GCCCAGACGCCCGAGAAGGCCATCGCGCGGATGGACCGGGCCTTGCGCGAGTTCCGGGTGCGCGGCGTGGCGACGAATAT
CGAATTCGTCATCAACCTGCTGAAACACCCGACCTTCCTCGACGACAGCTATACGACTAAGTTCATCGATACCACGCCGG
ACCTGTTCGCGTTCCGCAAGCGCCGCGACCGGGCGACGAAACTGCTGGTCTACATCGCCGACATCACCGTGAACGGCCAT
CCCGAGACCGCCGGCCGGCCGCTGCCGCCGGCCGAGGCGCGCATTCCCGTGCCGCCTGCGGCCAAGGCCGAGCCCGCCCC
CGGCACGCGGCAGCTCCTGGAGGAACGGGGGGCGAAAGCCGTCGCCGACTGGATGCTGGACCAGAAGCGCCTGCTGATCA
CCGACACCTCGATGCGCGACGGCCACCAGAGCTTGCTCGCCACGCGGATGCGCTCGATCGACATGATCCGGGTGGCGCCG
GCCTATGCCGCGAACCTGCCCGGCCTCTTCTCGGTCGAATGCTGGGGCGGCGCGACTTTCGATGTCGCCTATCGCTTCCT
GCAGGAATGCCCCTGGCAGCGGCTGCGCGACATCCGCGCCCGCATGCCCAACCTGATGACGCAGATGCTGCTGCGGGCCA
GCAACGGCGTCGGCTACACCAACTATCCCGACAATGTGGTGCAGGAATTCGTCCGCCAGGCGGCCAGGACCGGCGTGGAC
GTGTTCCGGGTCTTCGACAGCCTGAACTGGACCCCGAACATGCGCGTCGCCATGGATGCGGTGATCGAGGCCGGCAAGAT
CTGCGAGGGCACCATCTGCTATACCGGCGACCTGCTCGATCCCGCGCGCGCGAAATACGACCTGCAATATTACCTGAAGA
TGGCGCGCGAGTTGCGCGACGCCGGCGCGCATGTGCTGGGGCTGAAGGACATGGCGGGGCTGCTGAAACCCGCCTCGGCC
GGCATTCTGGTCCGCGCGCTGAAGGAAGAGATCGGCCTGCCGGTGCATTTCCACACCCATGACACCGGCGGCATTGCCGG
CGCCTCGATCCTGGCCGCGGCCGAGGCCGGGGTGGATGCGGTGGACTGCGCCATGGACGCCTTTTCCGGCAATACCTCGC
AGCCCTGCCTGGGCTCGGTGGTCGAGGCGCTGCGCCACACCGATCGCGACACCGGCCTGGATATCGAGGCGATCCGCCGG
ATCTCGAACTACTGGGAGGCGGTGCGCGAGCACTATGCCGCCTTCGAGAGCGGCTTGCAGGCCCCGGCCTCGGAGGTCTG
GCTGCACGAGATGCCCGGCGGCCAGTTCACCAATCTCAAGGCCCAGGCGCGCTCGCTCGGCCTTGAGGATCGCTGGCACG
AGGTCGCCCAGGCCTATGCCGAGGTGAACCGGATGTTCGGCGACATCGTCAAGGTCACGCCCAGTTCCAAGGTGGTGGGC
GACATGGCGCTGATGATGGTGGCGCAGGGGCTGACGCGGGCGCAGGTCGAGGACCCGGCGGTCGAGGTCTCCTTCCCCGA
CAGCGTCGTCGACATGATGCGCGGCAACCTGGGCCAGCCGCCCGGGGGCTGGCCGGCGGCGTTGCAGAAGAAGGTCTTGA
AGGGCGAGCCAGCCCTGACCGCCCGCCCCGGCGCGGCCATGCCGCCGGTGGATATCGAGGCCACCCGCGCCGAGCTGATC
CGCCAGCTGGAAGGCAAGGCGGTCGACGACGAGGACCTGAACGGCTACCTGATGTATCCCAAGGTCTTCCTCGACTACAT
GGGCCGGCACCGGCAATACGGCCCGGTGCGGACGCTGCCGACGCGGACCTTCTTCTACGGCATGGAGCCGGGCGAGGAGA
TCGAGGCCGAGATCGACCCCGGCAAGACGCTGGAGATCCGGCTGCAGACCGTGGGCGAGACCGACGAGAAGGGCGAGGTC
AAGGTGTTCTTCGAGCTGAACGGCCAGCCCCGGGTGATCCGGGTGCCGAACCGTCTGGTCAAGTCGCAGACCGCCGCCCG
TCCCAAGGCCGACCCGGCGAACGAGGGCCACCTGGGCGCGCCCATGCCCGGCGTCGTCGCCTCGGTCGCCGTCACCCAGG
GGCAGAAGGTCAATCCCGGCGACCTGCTGCTGACCATCGAGGCGATGAAGATGGAAACCGGCATCCATGCCGACAGAGCC
GGCGTCATCAAGGCGCTGCACGTCAGGCCGGGAGAGCAGATCGACGCGAAGGATCTCATGGTCGAGATGGAGTGA

Upstream 100 bases:

>100_bases
GCTGAGATGAGAAAACCCGCGTCGCGAAACCGTCGCGAAGGGTGCTTGCGCTGCACCGCAGCATAGTTAGGATGCCCGCC
GGGCGAACATGGGGGGACTG

Downstream 100 bases:

>100_bases
GACGAGCCGGGGCGCGAAAGCGCCCCGGGCCGACCGGGAAAATCGTCGCCGGATCATGCCGCTACGGCACCATCCACGGA
ATGGCGCGGCAGGCTTGCAG

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1144; Mature: 1144

Protein sequence:

>1144_residues
MFRKILIANRGEIAIRVMRAANELGKKTVAVYAEEDKLSLHRFKADEAYRIGGGLGPVAAYLSIPEIIRVAKESGADAIH
PGYGLLSENPDFVDACTAAGIAFIGPSADTMRALGDKASARRVAIQAGVPVIPATEVLGEDMEAIKREAAEIGYPLMLKA
SWGGGGRGMRPIMGPEELPEKVREGRREAEAAFGNGEGYLEKMILRARHVEVQLLGDGHGGLYHLYERDCTVQRRNQKVV
ERAPAPYLTPEQRAEVCELALRIGRAVGYRNAGTVEFLMDMDSQAFYFIEVNPRVQVEHTVTEEVTGIDIVQSQILIAEG
ATLAQATGVASQAGVHLNGHALQCRVTTEDPLNNFIPDYGRITAYRSATGNGIRLDGGTAYSGGVITRYYDSLLVKVTAH
AQTPEKAIARMDRALREFRVRGVATNIEFVINLLKHPTFLDDSYTTKFIDTTPDLFAFRKRRDRATKLLVYIADITVNGH
PETAGRPLPPAEARIPVPPAAKAEPAPGTRQLLEERGAKAVADWMLDQKRLLITDTSMRDGHQSLLATRMRSIDMIRVAP
AYAANLPGLFSVECWGGATFDVAYRFLQECPWQRLRDIRARMPNLMTQMLLRASNGVGYTNYPDNVVQEFVRQAARTGVD
VFRVFDSLNWTPNMRVAMDAVIEAGKICEGTICYTGDLLDPARAKYDLQYYLKMARELRDAGAHVLGLKDMAGLLKPASA
GILVRALKEEIGLPVHFHTHDTGGIAGASILAAAEAGVDAVDCAMDAFSGNTSQPCLGSVVEALRHTDRDTGLDIEAIRR
ISNYWEAVREHYAAFESGLQAPASEVWLHEMPGGQFTNLKAQARSLGLEDRWHEVAQAYAEVNRMFGDIVKVTPSSKVVG
DMALMMVAQGLTRAQVEDPAVEVSFPDSVVDMMRGNLGQPPGGWPAALQKKVLKGEPALTARPGAAMPPVDIEATRAELI
RQLEGKAVDDEDLNGYLMYPKVFLDYMGRHRQYGPVRTLPTRTFFYGMEPGEEIEAEIDPGKTLEIRLQTVGETDEKGEV
KVFFELNGQPRVIRVPNRLVKSQTAARPKADPANEGHLGAPMPGVVASVAVTQGQKVNPGDLLLTIEAMKMETGIHADRA
GVIKALHVRPGEQIDAKDLMVEME

Sequences:

>Translated_1144_residues
MFRKILIANRGEIAIRVMRAANELGKKTVAVYAEEDKLSLHRFKADEAYRIGGGLGPVAAYLSIPEIIRVAKESGADAIH
PGYGLLSENPDFVDACTAAGIAFIGPSADTMRALGDKASARRVAIQAGVPVIPATEVLGEDMEAIKREAAEIGYPLMLKA
SWGGGGRGMRPIMGPEELPEKVREGRREAEAAFGNGEGYLEKMILRARHVEVQLLGDGHGGLYHLYERDCTVQRRNQKVV
ERAPAPYLTPEQRAEVCELALRIGRAVGYRNAGTVEFLMDMDSQAFYFIEVNPRVQVEHTVTEEVTGIDIVQSQILIAEG
ATLAQATGVASQAGVHLNGHALQCRVTTEDPLNNFIPDYGRITAYRSATGNGIRLDGGTAYSGGVITRYYDSLLVKVTAH
AQTPEKAIARMDRALREFRVRGVATNIEFVINLLKHPTFLDDSYTTKFIDTTPDLFAFRKRRDRATKLLVYIADITVNGH
PETAGRPLPPAEARIPVPPAAKAEPAPGTRQLLEERGAKAVADWMLDQKRLLITDTSMRDGHQSLLATRMRSIDMIRVAP
AYAANLPGLFSVECWGGATFDVAYRFLQECPWQRLRDIRARMPNLMTQMLLRASNGVGYTNYPDNVVQEFVRQAARTGVD
VFRVFDSLNWTPNMRVAMDAVIEAGKICEGTICYTGDLLDPARAKYDLQYYLKMARELRDAGAHVLGLKDMAGLLKPASA
GILVRALKEEIGLPVHFHTHDTGGIAGASILAAAEAGVDAVDCAMDAFSGNTSQPCLGSVVEALRHTDRDTGLDIEAIRR
ISNYWEAVREHYAAFESGLQAPASEVWLHEMPGGQFTNLKAQARSLGLEDRWHEVAQAYAEVNRMFGDIVKVTPSSKVVG
DMALMMVAQGLTRAQVEDPAVEVSFPDSVVDMMRGNLGQPPGGWPAALQKKVLKGEPALTARPGAAMPPVDIEATRAELI
RQLEGKAVDDEDLNGYLMYPKVFLDYMGRHRQYGPVRTLPTRTFFYGMEPGEEIEAEIDPGKTLEIRLQTVGETDEKGEV
KVFFELNGQPRVIRVPNRLVKSQTAARPKADPANEGHLGAPMPGVVASVAVTQGQKVNPGDLLLTIEAMKMETGIHADRA
GVIKALHVRPGEQIDAKDLMVEME
>Mature_1144_residues
MFRKILIANRGEIAIRVMRAANELGKKTVAVYAEEDKLSLHRFKADEAYRIGGGLGPVAAYLSIPEIIRVAKESGADAIH
PGYGLLSENPDFVDACTAAGIAFIGPSADTMRALGDKASARRVAIQAGVPVIPATEVLGEDMEAIKREAAEIGYPLMLKA
SWGGGGRGMRPIMGPEELPEKVREGRREAEAAFGNGEGYLEKMILRARHVEVQLLGDGHGGLYHLYERDCTVQRRNQKVV
ERAPAPYLTPEQRAEVCELALRIGRAVGYRNAGTVEFLMDMDSQAFYFIEVNPRVQVEHTVTEEVTGIDIVQSQILIAEG
ATLAQATGVASQAGVHLNGHALQCRVTTEDPLNNFIPDYGRITAYRSATGNGIRLDGGTAYSGGVITRYYDSLLVKVTAH
AQTPEKAIARMDRALREFRVRGVATNIEFVINLLKHPTFLDDSYTTKFIDTTPDLFAFRKRRDRATKLLVYIADITVNGH
PETAGRPLPPAEARIPVPPAAKAEPAPGTRQLLEERGAKAVADWMLDQKRLLITDTSMRDGHQSLLATRMRSIDMIRVAP
AYAANLPGLFSVECWGGATFDVAYRFLQECPWQRLRDIRARMPNLMTQMLLRASNGVGYTNYPDNVVQEFVRQAARTGVD
VFRVFDSLNWTPNMRVAMDAVIEAGKICEGTICYTGDLLDPARAKYDLQYYLKMARELRDAGAHVLGLKDMAGLLKPASA
GILVRALKEEIGLPVHFHTHDTGGIAGASILAAAEAGVDAVDCAMDAFSGNTSQPCLGSVVEALRHTDRDTGLDIEAIRR
ISNYWEAVREHYAAFESGLQAPASEVWLHEMPGGQFTNLKAQARSLGLEDRWHEVAQAYAEVNRMFGDIVKVTPSSKVVG
DMALMMVAQGLTRAQVEDPAVEVSFPDSVVDMMRGNLGQPPGGWPAALQKKVLKGEPALTARPGAAMPPVDIEATRAELI
RQLEGKAVDDEDLNGYLMYPKVFLDYMGRHRQYGPVRTLPTRTFFYGMEPGEEIEAEIDPGKTLEIRLQTVGETDEKGEV
KVFFELNGQPRVIRVPNRLVKSQTAARPKADPANEGHLGAPMPGVVASVAVTQGQKVNPGDLLLTIEAMKMETGIHADRA
GVIKALHVRPGEQIDAKDLMVEME

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1149, Percent_Identity=49.1731940818103, Blast_Score=1081, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1149, Percent_Identity=49.1731940818103, Blast_Score=1081, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1149, Percent_Identity=49.1731940818103, Blast_Score=1081, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=449, Percent_Identity=43.8752783964365, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI189095269, Length=459, Percent_Identity=42.483660130719, Blast_Score=337, Evalue=4e-92,
Organism=Homo sapiens, GI65506442, Length=459, Percent_Identity=42.483660130719, Blast_Score=337, Evalue=5e-92,
Organism=Homo sapiens, GI295821183, Length=459, Percent_Identity=42.483660130719, Blast_Score=337, Evalue=5e-92,
Organism=Homo sapiens, GI38679977, Length=556, Percent_Identity=30.0359712230216, Blast_Score=229, Evalue=2e-59,
Organism=Homo sapiens, GI38679967, Length=556, Percent_Identity=30.0359712230216, Blast_Score=229, Evalue=2e-59,
Organism=Homo sapiens, GI38679974, Length=556, Percent_Identity=30.0359712230216, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI38679971, Length=556, Percent_Identity=30.0359712230216, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI38679960, Length=556, Percent_Identity=30.0359712230216, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI134142062, Length=507, Percent_Identity=32.5443786982249, Blast_Score=224, Evalue=4e-58,
Organism=Escherichia coli, GI1789654, Length=440, Percent_Identity=46.3636363636364, Blast_Score=357, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17562816, Length=1148, Percent_Identity=51.0452961672474, Blast_Score=1144, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=459, Percent_Identity=45.0980392156863, Blast_Score=359, Evalue=5e-99,
Organism=Caenorhabditis elegans, GI17567343, Length=461, Percent_Identity=42.2993492407809, Blast_Score=330, Evalue=4e-90,
Organism=Caenorhabditis elegans, GI133931226, Length=499, Percent_Identity=31.8637274549098, Blast_Score=211, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71997168, Length=440, Percent_Identity=30, Blast_Score=204, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI71997163, Length=440, Percent_Identity=30, Blast_Score=204, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1156, Percent_Identity=47.2318339100346, Blast_Score=1053, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1156, Percent_Identity=47.7508650519031, Blast_Score=1038, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=451, Percent_Identity=40.7982261640798, Blast_Score=337, Evalue=5e-93,
Organism=Saccharomyces cerevisiae, GI6324343, Length=514, Percent_Identity=31.1284046692607, Blast_Score=228, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6323863, Length=454, Percent_Identity=32.15859030837, Blast_Score=221, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24652212, Length=1152, Percent_Identity=49.7395833333333, Blast_Score=1099, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1152, Percent_Identity=49.7395833333333, Blast_Score=1099, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1152, Percent_Identity=49.7395833333333, Blast_Score=1099, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1152, Percent_Identity=49.7395833333333, Blast_Score=1099, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1152, Percent_Identity=49.7395833333333, Blast_Score=1099, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1168, Percent_Identity=49.1438356164384, Blast_Score=1094, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1168, Percent_Identity=49.1438356164384, Blast_Score=1094, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1168, Percent_Identity=49.1438356164384, Blast_Score=1094, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1168, Percent_Identity=49.1438356164384, Blast_Score=1094, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1168, Percent_Identity=49.1438356164384, Blast_Score=1094, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=452, Percent_Identity=41.1504424778761, Blast_Score=353, Evalue=4e-97,
Organism=Drosophila melanogaster, GI24651759, Length=416, Percent_Identity=39.4230769230769, Blast_Score=311, Evalue=2e-84,
Organism=Drosophila melanogaster, GI161076409, Length=532, Percent_Identity=30.4511278195489, Blast_Score=216, Evalue=9e-56,
Organism=Drosophila melanogaster, GI161076407, Length=532, Percent_Identity=30.4511278195489, Blast_Score=216, Evalue=9e-56,
Organism=Drosophila melanogaster, GI24586460, Length=532, Percent_Identity=30.4511278195489, Blast_Score=216, Evalue=9e-56,
Organism=Drosophila melanogaster, GI24586458, Length=532, Percent_Identity=30.4511278195489, Blast_Score=216, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 125170; Mature: 125170

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRKILIANRGEIAIRVMRAANELGKKTVAVYAEEDKLSLHRFKADEAYRIGGGLGPVAA
CCCEEEEECCCCEEHHHHHHHHHHCCCEEEEEECCCCCCHHHCCCCCCEEECCCHHHHHH
YLSIPEIIRVAKESGADAIHPGYGLLSENPDFVDACTAAGIAFIGPSADTMRALGDKASA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHCCCCCC
RRVAIQAGVPVIPATEVLGEDMEAIKREAAEIGYPLMLKASWGGGGRGMRPIMGPEELPE
CEEEEECCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHH
KVREGRREAEAAFGNGEGYLEKMILRARHVEVQLLGDGHGGLYHLYERDCTVQRRNQKVV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEECCCCCEEEEECCCCHHHHHHHHHH
ERAPAPYLTPEQRAEVCELALRIGRAVGYRNAGTVEFLMDMDSQAFYFIEVNPRVQVEHT
HHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCEEEEEE
VTEEVTGIDIVQSQILIAEGATLAQATGVASQAGVHLNGHALQCRVTTEDPLNNFIPDYG
HHHHHCCHHHHHHEEEEECCCHHHHHCCCHHHCCEEECCCEEEEEECCCCCHHHHCCCCC
RITAYRSATGNGIRLDGGTAYSGGVITRYYDSLLVKVTAHAQTPEKAIARMDRALREFRV
CEEEEECCCCCCEEECCCCEECCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHH
RGVATNIEFVINLLKHPTFLDDSYTTKFIDTTPDLFAFRKRRDRATKLLVYIADITVNGH
HHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHEEEEEEEEEEECCC
PETAGRPLPPAEARIPVPPAAKAEPAPGTRQLLEERGAKAVADWMLDQKRLLITDTSMRD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCEEEEEECCCCC
GHQSLLATRMRSIDMIRVAPAYAANLPGLFSVECWGGATFDVAYRFLQECPWQRLRDIRA
HHHHHHHHHHHHCCEEEECCHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHH
RMPNLMTQMLLRASNGVGYTNYPDNVVQEFVRQAARTGVDVFRVFDSLNWTPNMRVAMDA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHH
VIEAGKICEGTICYTGDLLDPARAKYDLQYYLKMARELRDAGAHVLGLKDMAGLLKPASA
HHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCC
GILVRALKEEIGLPVHFHTHDTGGIAGASILAAAEAGVDAVDCAMDAFSGNTSQPCLGSV
HHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHH
VEALRHTDRDTGLDIEAIRRISNYWEAVREHYAAFESGLQAPASEVWLHEMPGGQFTNLK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEECCCCCCCCHH
AQARSLGLEDRWHEVAQAYAEVNRMFGDIVKVTPSSKVVGDMALMMVAQGLTRAQVEDPA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCHHHHCCCCE
VEVSFPDSVVDMMRGNLGQPPGGWPAALQKKVLKGEPALTARPGAAMPPVDIEATRAELI
EEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHH
RQLEGKAVDDEDLNGYLMYPKVFLDYMGRHRQYGPVRTLPTRTFFYGMEPGEEIEAEIDP
HHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCEEECCC
GKTLEIRLQTVGETDEKGEVKVFFELNGQPRVIRVPNRLVKSQTAARPKADPANEGHLGA
CCEEEEEEEECCCCCCCCCEEEEEEECCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCC
PMPGVVASVAVTQGQKVNPGDLLLTIEAMKMETGIHADRAGVIKALHVRPGEQIDAKDLM
CCCHHHHHHHHHCCCCCCCCCEEEEEEEEHHHCCCCCCCCCCEEEEECCCCCCCCCCCCE
VEME
EECC
>Mature Secondary Structure
MFRKILIANRGEIAIRVMRAANELGKKTVAVYAEEDKLSLHRFKADEAYRIGGGLGPVAA
CCCEEEEECCCCEEHHHHHHHHHHCCCEEEEEECCCCCCHHHCCCCCCEEECCCHHHHHH
YLSIPEIIRVAKESGADAIHPGYGLLSENPDFVDACTAAGIAFIGPSADTMRALGDKASA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHCCCCCC
RRVAIQAGVPVIPATEVLGEDMEAIKREAAEIGYPLMLKASWGGGGRGMRPIMGPEELPE
CEEEEECCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHH
KVREGRREAEAAFGNGEGYLEKMILRARHVEVQLLGDGHGGLYHLYERDCTVQRRNQKVV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEECCCCCEEEEECCCCHHHHHHHHHH
ERAPAPYLTPEQRAEVCELALRIGRAVGYRNAGTVEFLMDMDSQAFYFIEVNPRVQVEHT
HHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCEEEEEE
VTEEVTGIDIVQSQILIAEGATLAQATGVASQAGVHLNGHALQCRVTTEDPLNNFIPDYG
HHHHHCCHHHHHHEEEEECCCHHHHHCCCHHHCCEEECCCEEEEEECCCCCHHHHCCCCC
RITAYRSATGNGIRLDGGTAYSGGVITRYYDSLLVKVTAHAQTPEKAIARMDRALREFRV
CEEEEECCCCCCEEECCCCEECCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHH
RGVATNIEFVINLLKHPTFLDDSYTTKFIDTTPDLFAFRKRRDRATKLLVYIADITVNGH
HHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHEEEEEEEEEEECCC
PETAGRPLPPAEARIPVPPAAKAEPAPGTRQLLEERGAKAVADWMLDQKRLLITDTSMRD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCEEEEEECCCCC
GHQSLLATRMRSIDMIRVAPAYAANLPGLFSVECWGGATFDVAYRFLQECPWQRLRDIRA
HHHHHHHHHHHHCCEEEECCHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHH
RMPNLMTQMLLRASNGVGYTNYPDNVVQEFVRQAARTGVDVFRVFDSLNWTPNMRVAMDA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHH
VIEAGKICEGTICYTGDLLDPARAKYDLQYYLKMARELRDAGAHVLGLKDMAGLLKPASA
HHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCC
GILVRALKEEIGLPVHFHTHDTGGIAGASILAAAEAGVDAVDCAMDAFSGNTSQPCLGSV
HHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHH
VEALRHTDRDTGLDIEAIRRISNYWEAVREHYAAFESGLQAPASEVWLHEMPGGQFTNLK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEECCCCCCCCHH
AQARSLGLEDRWHEVAQAYAEVNRMFGDIVKVTPSSKVVGDMALMMVAQGLTRAQVEDPA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCHHHHCCCCE
VEVSFPDSVVDMMRGNLGQPPGGWPAALQKKVLKGEPALTARPGAAMPPVDIEATRAELI
EEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHH
RQLEGKAVDDEDLNGYLMYPKVFLDYMGRHRQYGPVRTLPTRTFFYGMEPGEEIEAEIDP
HHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCEEECCC
GKTLEIRLQTVGETDEKGEVKVFFELNGQPRVIRVPNRLVKSQTAARPKADPANEGHLGA
CCEEEEEEEECCCCCCCCCEEEEEEECCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCC
PMPGVVASVAVTQGQKVNPGDLLLTIEAMKMETGIHADRAGVIKALHVRPGEQIDAKDLM
CCCHHHHHHHHHCCCCCCCCCEEEEEEEEHHHCCCCCCCCCCEEEEECCCCCCCCCCCCE
VEME
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]