Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 119358488

GI number: 119358488

Start: 3114704

End: 3115810

Strand: Reverse

Name: mraY

Synonym: Cpha266_2724

Alternate gene names: 119358488

Gene position: 3115810-3114704 (Counterclockwise)

Preceding gene: 119358489

Following gene: 119358487

Centisome position: 99.42

GC content: 49.23

Gene sequence:

>1107_bases
ATGCTTTATTATCTTCTGAAATACATTAACGATGTGTTTGATCCCCCGGGGTTCGGCGTCATCGAATTCCTGACGTTCAG
GGCAAGCGCAGCGGCAATAACGGCGCTTTTGATCAGTCTTATGGCGGGGCCGTGGTTTATCCGCTATCTCAAAGGCCGTT
TTATCGAGCCGGTCAAAGAGGAGGCGCCTCCCGAACATAAAAAGAAAAAAGAGCTCCCTACCATGGGTGGCATTCTGATC
ATCTTTTCCATCGAGGTATCGGTATTTCTCTGGGCAAAATTTGATGATCCTCACGTCTGGCTTGTCATGCTTGCCATTTT
CTGGATGGGTCTTATCGGGTTTATTGACGACTATCGAAAGGTTGTCCTCAAGATCAAGGGCGGTTTATCGGCGCGCTACA
AACTTCTTGGCCAGATATCCCTTGGCCTTGTGATCGGCCTCTATACATGGTTCGACCCGGCTTTTGCCGTTCTGTTGTCA
AAAACCACCATACCGTTTATCAAACAACTGAGCATCGACTACGGGATTTTCTATATCCCGATTGTCATCTTTATCATCAC
GGCCGTCTCAAACTCAGTGAACCTCACCGACGGGCTTGACGGGCTTGCCTCCGGAACGACGGCTATTGTGGTATCCGCTC
TTGGCGCGTTCTCCTATCTGGCAGGCAACGCGGTCTATGCCGATTATCTGAAAATTCCCTTTATTCCCGGAGGTGGCGAG
ATTGCCGTTGTCTGTATGGCAATCGTGATGGCATGCGTTGGTTTTTTATGGTTTAATTCCAATCCGGCGGAGATCATTAT
GGGCGATACCGGTTCGCTTGCCCTCGGCAGCGCGGTTGCCGTTATTGCGCTGCTCATCAAACAGGAACTGCTCCTGCCGG
TGCTTGCCGGCGTTTTTGTTCTTGAAGCTCTGTCGGTTTCAATGCAGGTGCTCTACTTCAAACTGACAAAAAAGCTCTCG
GGTCAAGGGCGCCGAATATTTCTGATGGCCCCGCTGCACCACCATTTTCAGCTGAAAGGATGGGCAGAACAGAAAATCGT
TATCAGGTTCTGGATTATAAGCATTCTGTTTTTTTTAACGAGTCTTATGACCTTAAAGCTCAGGTGA

Upstream 100 bases:

>100_bases
GGGTGACGCCGTGCTGTTCAAGGCATCAAGAAGTATGCGGCTTGAGCTGGTTGTCGAGGCGCTGATCAAAGAAAGAACAA
CAATGTAGAAAGGGCACGGC

Downstream 100 bases:

>100_bases
TGGACGTTGCGGGTAAAAAAGTAGCCGTGCTTGGCGCAAGACGAAGCGGTATGGCAGTTGCCGAACTGCTTTCGCTTAAA
GGAGCCTCGGTCTTTGTAAG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MLYYLLKYINDVFDPPGFGVIEFLTFRASAAAITALLISLMAGPWFIRYLKGRFIEPVKEEAPPEHKKKKELPTMGGILI
IFSIEVSVFLWAKFDDPHVWLVMLAIFWMGLIGFIDDYRKVVLKIKGGLSARYKLLGQISLGLVIGLYTWFDPAFAVLLS
KTTIPFIKQLSIDYGIFYIPIVIFIITAVSNSVNLTDGLDGLASGTTAIVVSALGAFSYLAGNAVYADYLKIPFIPGGGE
IAVVCMAIVMACVGFLWFNSNPAEIIMGDTGSLALGSAVAVIALLIKQELLLPVLAGVFVLEALSVSMQVLYFKLTKKLS
GQGRRIFLMAPLHHHFQLKGWAEQKIVIRFWIISILFFLTSLMTLKLR

Sequences:

>Translated_368_residues
MLYYLLKYINDVFDPPGFGVIEFLTFRASAAAITALLISLMAGPWFIRYLKGRFIEPVKEEAPPEHKKKKELPTMGGILI
IFSIEVSVFLWAKFDDPHVWLVMLAIFWMGLIGFIDDYRKVVLKIKGGLSARYKLLGQISLGLVIGLYTWFDPAFAVLLS
KTTIPFIKQLSIDYGIFYIPIVIFIITAVSNSVNLTDGLDGLASGTTAIVVSALGAFSYLAGNAVYADYLKIPFIPGGGE
IAVVCMAIVMACVGFLWFNSNPAEIIMGDTGSLALGSAVAVIALLIKQELLLPVLAGVFVLEALSVSMQVLYFKLTKKLS
GQGRRIFLMAPLHHHFQLKGWAEQKIVIRFWIISILFFLTSLMTLKLR
>Mature_368_residues
MLYYLLKYINDVFDPPGFGVIEFLTFRASAAAITALLISLMAGPWFIRYLKGRFIEPVKEEAPPEHKKKKELPTMGGILI
IFSIEVSVFLWAKFDDPHVWLVMLAIFWMGLIGFIDDYRKVVLKIKGGLSARYKLLGQISLGLVIGLYTWFDPAFAVLLS
KTTIPFIKQLSIDYGIFYIPIVIFIITAVSNSVNLTDGLDGLASGTTAIVVSALGAFSYLAGNAVYADYLKIPFIPGGGE
IAVVCMAIVMACVGFLWFNSNPAEIIMGDTGSLALGSAVAVIALLIKQELLLPVLAGVFVLEALSVSMQVLYFKLTKKLS
GQGRRIFLMAPLHHHFQLKGWAEQKIVIRFWIISILFFLTSLMTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=371, Percent_Identity=45.822102425876, Blast_Score=303, Evalue=8e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_CHLPD (A1BJY1)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_913132.1
- STRING:   A1BJY1
- GeneID:   4570698
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2724
- NMPDR:   fig|290317.7.peg.2845
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 40746; Mature: 40746

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12e547bc)-; HASH(0x13958db0)-; HASH(0x139701b4)-; HASH(0x139704f0)-; HASH(0x13958f54)-; HASH(0x1397fe3c)-; HASH(0x12df9d34)-; HASH(0x135e66b4)-; HASH(0x139701fc)-; HASH(0x1397fecc)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYYLLKYINDVFDPPGFGVIEFLTFRASAAAITALLISLMAGPWFIRYLKGRFIEPVKE
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
EAPPEHKKKKELPTMGGILIIFSIEVSVFLWAKFDDPHVWLVMLAIFWMGLIGFIDDYRK
CCCCCHHHHHCCCCCCCEEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
VVLKIKGGLSARYKLLGQISLGLVIGLYTWFDPAFAVLLSKTTIPFIKQLSIDYGIFYIP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHH
IVIFIITAVSNSVNLTDGLDGLASGTTAIVVSALGAFSYLAGNAVYADYLKIPFIPGGGE
HHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCEEEHHEEECEECCCCH
IAVVCMAIVMACVGFLWFNSNPAEIIMGDTGSLALGSAVAVIALLIKQELLLPVLAGVFV
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEALSVSMQVLYFKLTKKLSGQGRRIFLMAPLHHHFQLKGWAEQKIVIRFWIISILFFLT
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHH
SLMTLKLR
HHHHHCCH
>Mature Secondary Structure
MLYYLLKYINDVFDPPGFGVIEFLTFRASAAAITALLISLMAGPWFIRYLKGRFIEPVKE
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
EAPPEHKKKKELPTMGGILIIFSIEVSVFLWAKFDDPHVWLVMLAIFWMGLIGFIDDYRK
CCCCCHHHHHCCCCCCCEEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
VVLKIKGGLSARYKLLGQISLGLVIGLYTWFDPAFAVLLSKTTIPFIKQLSIDYGIFYIP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHH
IVIFIITAVSNSVNLTDGLDGLASGTTAIVVSALGAFSYLAGNAVYADYLKIPFIPGGGE
HHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCEEEHHEEECEECCCCH
IAVVCMAIVMACVGFLWFNSNPAEIIMGDTGSLALGSAVAVIALLIKQELLLPVLAGVFV
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEALSVSMQVLYFKLTKKLSGQGRRIFLMAPLHHHFQLKGWAEQKIVIRFWIISILFFLT
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHH
SLMTLKLR
HHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA