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The map label for this gene is ribH

Identifier: 119358316

GI number: 119358316

Start: 2926211

End: 2926678

Strand: Reverse

Name: ribH

Synonym: Cpha266_2548

Alternate gene names: 119358316

Gene position: 2926678-2926211 (Counterclockwise)

Preceding gene: 119358317

Following gene: 119358312

Centisome position: 93.39

GC content: 53.21

Gene sequence:

>468_bases
ATGCAGATCAAACAGATTGAGGGGTCGCTGAGCGCAAAGGGCGCGAGGTTTGCGCTGGTTGTTTCCCGTTTTAATGATTT
TATCGGTCAGAAGCTGGTTGAGGGGGCTCTGGATTGCCTTCGTCGTCATGGAGCGGAGGATTCGGAGGTGGTGATTTATC
GCTGTCCCGGCGCTTTTGAGCTGCCTATGGTGGCTAAAAAAGCTGCTTTAAGCGGTAATCACGATGCCGTTATTGCGCTT
GGAGTCATTATCAGGGGCTCGACGCCGCATTTTGACGTGATTGCCGCCGAAGCTACCAAGGGTCTGGCTCAGGTTGCCCT
TGATACCATGATACCTGTCGCTTTCGGGGTGCTGACGACGGAGAATCTGGAACAGGCTATCGAGCGTGCCGGGACGAAAG
CGGGAAACAAGGGATTCGATGCCGCGATGACCGTTATTGAGATGGTGAATCTCTATCGTCAGTTTTAG

Upstream 100 bases:

>100_bases
CAGGAGTGTCATATTACGCTTGGTCACGTTATTATTGATCTTGTTGAGCGGATGATGGGGTACGGTACGGAGTGCAATAA
TCAACAAAATGAACAAGGAT

Downstream 100 bases:

>100_bases
GGGGTGCCTTTTGTGTTTTCACGCATTCAGTTGAACCGGTAGCGCTGCAGGTTGCCTTCGATTGTTCTGAATGATTCAAG
CATGAGATCTTCAATACTTT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MQIKQIEGSLSAKGARFALVVSRFNDFIGQKLVEGALDCLRRHGAEDSEVVIYRCPGAFELPMVAKKAALSGNHDAVIAL
GVIIRGSTPHFDVIAAEATKGLAQVALDTMIPVAFGVLTTENLEQAIERAGTKAGNKGFDAAMTVIEMVNLYRQF

Sequences:

>Translated_155_residues
MQIKQIEGSLSAKGARFALVVSRFNDFIGQKLVEGALDCLRRHGAEDSEVVIYRCPGAFELPMVAKKAALSGNHDAVIAL
GVIIRGSTPHFDVIAAEATKGLAQVALDTMIPVAFGVLTTENLEQAIERAGTKAGNKGFDAAMTVIEMVNLYRQF
>Mature_155_residues
MQIKQIEGSLSAKGARFALVVSRFNDFIGQKLVEGALDCLRRHGAEDSEVVIYRCPGAFELPMVAKKAALSGNHDAVIAL
GVIIRGSTPHFDVIAAEATKGLAQVALDTMIPVAFGVLTTENLEQAIERAGTKAGNKGFDAAMTVIEMVNLYRQF

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=149, Percent_Identity=54.3624161073826, Blast_Score=169, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6324429, Length=142, Percent_Identity=35.2112676056338, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_CHLPD (A1BJF9)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912960.1
- ProteinModelPortal:   A1BJF9
- SMR:   A1BJF9
- STRING:   A1BJF9
- GeneID:   4569004
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2548
- NMPDR:   fig|290317.7.peg.2665
- eggNOG:   COG0054
- HOGENOM:   HBG311126
- OMA:   NRAGIKA
- ProtClustDB:   PRK00061
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16591; Mature: 16591

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKQIEGSLSAKGARFALVVSRFNDFIGQKLVEGALDCLRRHGAEDSEVVIYRCPGAFE
CCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
LPMVAKKAALSGNHDAVIALGVIIRGSTPHFDVIAAEATKGLAQVALDTMIPVAFGVLTT
CHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ENLEQAIERAGTKAGNKGFDAAMTVIEMVNLYRQF
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQIKQIEGSLSAKGARFALVVSRFNDFIGQKLVEGALDCLRRHGAEDSEVVIYRCPGAFE
CCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
LPMVAKKAALSGNHDAVIALGVIIRGSTPHFDVIAAEATKGLAQVALDTMIPVAFGVLTT
CHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ENLEQAIERAGTKAGNKGFDAAMTVIEMVNLYRQF
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA