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The map label for this gene is gmhA

Identifier: 119358317

GI number: 119358317

Start: 2926659

End: 2927339

Strand: Reverse

Name: gmhA

Synonym: Cpha266_2549

Alternate gene names: 119358317

Gene position: 2927339-2926659 (Counterclockwise)

Preceding gene: 119358320

Following gene: 119358316

Centisome position: 93.41

GC content: 54.77

Gene sequence:

>681_bases
ATGAGAAGAAAGTCCGGATGTTCGGCGGGGCTTGATGACCGTTCCGCTTATGAGGAGGTTGTGCTTGATTCGATGCTCTA
TAGCGCGCGGCTCAAAGAGACTGTTGCCCGTGGGAACAGCGCAGTCGTTGTGGCGATGGCAAGATTGATCGCCGGCGTTT
TCGAAACGGGCGGCAAGCTGCTGATCTGCGGCAATGGCGGCAGTGCGGCTGACGCACAGCATCTGGCAACTGAGTTTACG
ATTCGATACAGGTCGAGCGTACACCGTCCGGCGCTCCCTGCAATAGCCCTGACTACGGATAGTTCCGCGCTGACTGCCGG
GGCGAATGATCTGGGTTATGACGAGGTTTTCAGAAGGCTTGTGGAGGCTTACGGGAGGCCTGGCGATCTTCTGCTGGGTC
TTTCAACAAGCGGAAACAGCAGAAGCGTTGTGCATGCGCTCGATTATGCCCGAAAGCACGGGATGAGGACTCTTGCACTG
CTCGGCGGTGACGGAGGTGCGCTCAAAGGGCTGGCGGATCTATCCGTTGTGGTTCCTCATAACGGTTCGGCCGACAGGGT
TCAGGAGTGTCATATTACGCTTGGTCACGTTATTATTGATCTTGTTGAGCGGATGATGGGGTACGGTACGGAGTGCAATA
ATCAACAAAATGAACAAGGATATGCAGATCAAACAGATTGA

Upstream 100 bases:

>100_bases
TTCTCTTCTCCCCGGGGCTCCCTTCAGGGTATGCGGGCTTGTATTTTTTCATTATATTGCCGTTCGATATGGTGTTAACG
ATCTGTAACTGTTGTCTGCT

Downstream 100 bases:

>100_bases
GGGGTCGCTGAGCGCAAAGGGCGCGAGGTTTGCGCTGGTTGTTTCCCGTTTTAATGATTTTATCGGTCAGAAGCTGGTTG
AGGGGGCTCTGGATTGCCTT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MRRKSGCSAGLDDRSAYEEVVLDSMLYSARLKETVARGNSAVVVAMARLIAGVFETGGKLLICGNGGSAADAQHLATEFT
IRYRSSVHRPALPAIALTTDSSALTAGANDLGYDEVFRRLVEAYGRPGDLLLGLSTSGNSRSVVHALDYARKHGMRTLAL
LGGDGGALKGLADLSVVVPHNGSADRVQECHITLGHVIIDLVERMMGYGTECNNQQNEQGYADQTD

Sequences:

>Translated_226_residues
MRRKSGCSAGLDDRSAYEEVVLDSMLYSARLKETVARGNSAVVVAMARLIAGVFETGGKLLICGNGGSAADAQHLATEFT
IRYRSSVHRPALPAIALTTDSSALTAGANDLGYDEVFRRLVEAYGRPGDLLLGLSTSGNSRSVVHALDYARKHGMRTLAL
LGGDGGALKGLADLSVVVPHNGSADRVQECHITLGHVIIDLVERMMGYGTECNNQQNEQGYADQTD
>Mature_226_residues
MRRKSGCSAGLDDRSAYEEVVLDSMLYSARLKETVARGNSAVVVAMARLIAGVFETGGKLLICGNGGSAADAQHLATEFT
IRYRSSVHRPALPAIALTTDSSALTAGANDLGYDEVFRRLVEAYGRPGDLLLGLSTSGNSRSVVHALDYARKHGMRTLAL
LGGDGGALKGLADLSVVVPHNGSADRVQECHITLGHVIIDLVERMMGYGTECNNQQNEQGYADQTD

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1786416, Length=160, Percent_Identity=51.25, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1789539, Length=153, Percent_Identity=45.7516339869281, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GMHA_CHLPD (A1BJG0)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912961.1
- ProteinModelPortal:   A1BJG0
- SMR:   A1BJG0
- STRING:   A1BJG0
- GeneID:   4569005
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2549
- NMPDR:   fig|290317.7.peg.2666
- eggNOG:   COG0279
- HOGENOM:   HBG671955
- OMA:   ANDLGYD
- ProtClustDB:   CLSK638055
- GO:   GO:0005737
- HAMAP:   MF_00067
- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00441

Pfam domain/function: PF01380 SIS

EC number: =5.3.1.28

Molecular weight: Translated: 23981; Mature: 23981

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS51464 SIS

Important sites: BINDING 78-78 BINDING 140-140 BINDING 188-188

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKSGCSAGLDDRSAYEEVVLDSMLYSARLKETVARGNSAVVVAMARLIAGVFETGGKL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEE
LICGNGGSAADAQHLATEFTIRYRSSVHRPALPAIALTTDSSALTAGANDLGYDEVFRRL
EEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHCCCCCCCCHHHHHHHH
VEAYGRPGDLLLGLSTSGNSRSVVHALDYARKHGMRTLALLGGDGGALKGLADLSVVVPH
HHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHCCCCCEEEEECC
NGSADRVQECHITLGHVIIDLVERMMGYGTECNNQQNEQGYADQTD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRKSGCSAGLDDRSAYEEVVLDSMLYSARLKETVARGNSAVVVAMARLIAGVFETGGKL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEE
LICGNGGSAADAQHLATEFTIRYRSSVHRPALPAIALTTDSSALTAGANDLGYDEVFRRL
EEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHCCCCCCCCHHHHHHHH
VEAYGRPGDLLLGLSTSGNSRSVVHALDYARKHGMRTLALLGGDGGALKGLADLSVVVPH
HHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHCCCCCEEEEECC
NGSADRVQECHITLGHVIIDLVERMMGYGTECNNQQNEQGYADQTD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA