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The map label for this gene is glcK [H]

Identifier: 119358140

GI number: 119358140

Start: 2756441

End: 2757439

Strand: Reverse

Name: glcK [H]

Synonym: Cpha266_2372

Alternate gene names: 119358140

Gene position: 2757439-2756441 (Counterclockwise)

Preceding gene: 119358141

Following gene: 119358139

Centisome position: 87.99

GC content: 53.05

Gene sequence:

>999_bases
ATGCAGAGAGATATGTTTCGATGGGCTATAGGTATTGATCTTGGTGGTACGGCAATCAAGGGCGCAGTCATTGGTGAGCA
GGAGGGTATTGTCACCGAAAGGACAATACCGACCGACACGGCATCCGGACCCGAAGGTATTGTGGAACAGCTTGCCGGAT
TAATTGCAGCCCTGAAAGTGCAGGGCGCTCGTTTTTTTGACGCTTCGGGTTTTGCCGGTACAGGCCTTGGCGCGCCAGGA
GCGGTTAACGTTTCCCTCGGGACATTGAGCTACCCTCCCAATCTTCCCGGATGGACCGTTTTTCCTTTGTGTGACGCGTT
GCAGAACTGCCTGAAAGAGAAGGAGAATCTATCAGTATCGGTGATTCTTGAAAACGATGCCAACGCAGCAGCATTTGGTG
AAGCGATGTATGGCGCTGGCAAGCACTTCAGCGATTTTCTCATGGTTACGCTTGGAACCGGAGTCGGTGGCGGAATTATT
CTGAATCGACAACTCTACAGGGGGGCAAACGGAACCGCCGGCGAGGTGGGATTCATGATCGTTGATTATGAAGGAGCCCA
TGTTCATGCGGGGATTCGGGGAACTCTTGAAAGTCTTATCGGCAAAGAGCGCATCGTTGAACTTGCCAGCGGGATGATAA
AGGAAAACCCGTCGGCAGGCCATGCCGTTGCTGAACTTTGCGGCCATGATTTTACCCGGCTCTCTCCACGACATCTTGAA
CATGCAGCCAAGCAGGGCGATCCGCTCTCTCTTGCTCTCTGGCAGAGAGTTGGAGAGGCTCTTGGTGTTGGTTTGGCCAA
TGTTACCGCACTTATGGATATCCGGAAATTTGTGATAGGGGGCGGAATATCTGCTGCCGGAGACCTGATTATCACCCCTG
CATTCGAGCGGCTTCGTCGTTCAACGCTCCCCTCCATGCACGAAGGTCTCGATATTGTTCCTGCAGAGCTCGGAAACAGG
GCAGGGATGTACGGCGCTGCAGCGTTATGCTTTGTGTAA

Upstream 100 bases:

>100_bases
ACTTTCCTGCCGAGCCCGAAATTGTTGAAATACTCCGTTTTTTTGATTCCGGTACGCACGGAAGGAAATTCCTCAGGCCG
TTCAACAGTTAACCTGAATC

Downstream 100 bases:

>100_bases
CTGACAACCCGGGATGGTTGTATGGACGATCGACTGCTTCATTTTGTTTACCCCAATGTCTGTGTGGTATGCCAGAACCT
GCTTCTGGCATCAGAGCGTT

Product: ROK family protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MQRDMFRWAIGIDLGGTAIKGAVIGEQEGIVTERTIPTDTASGPEGIVEQLAGLIAALKVQGARFFDASGFAGTGLGAPG
AVNVSLGTLSYPPNLPGWTVFPLCDALQNCLKEKENLSVSVILENDANAAAFGEAMYGAGKHFSDFLMVTLGTGVGGGII
LNRQLYRGANGTAGEVGFMIVDYEGAHVHAGIRGTLESLIGKERIVELASGMIKENPSAGHAVAELCGHDFTRLSPRHLE
HAAKQGDPLSLALWQRVGEALGVGLANVTALMDIRKFVIGGGISAAGDLIITPAFERLRRSTLPSMHEGLDIVPAELGNR
AGMYGAAALCFV

Sequences:

>Translated_332_residues
MQRDMFRWAIGIDLGGTAIKGAVIGEQEGIVTERTIPTDTASGPEGIVEQLAGLIAALKVQGARFFDASGFAGTGLGAPG
AVNVSLGTLSYPPNLPGWTVFPLCDALQNCLKEKENLSVSVILENDANAAAFGEAMYGAGKHFSDFLMVTLGTGVGGGII
LNRQLYRGANGTAGEVGFMIVDYEGAHVHAGIRGTLESLIGKERIVELASGMIKENPSAGHAVAELCGHDFTRLSPRHLE
HAAKQGDPLSLALWQRVGEALGVGLANVTALMDIRKFVIGGGISAAGDLIITPAFERLRRSTLPSMHEGLDIVPAELGNR
AGMYGAAALCFV
>Mature_332_residues
MQRDMFRWAIGIDLGGTAIKGAVIGEQEGIVTERTIPTDTASGPEGIVEQLAGLIAALKVQGARFFDASGFAGTGLGAPG
AVNVSLGTLSYPPNLPGWTVFPLCDALQNCLKEKENLSVSVILENDANAAAFGEAMYGAGKHFSDFLMVTLGTGVGGGII
LNRQLYRGANGTAGEVGFMIVDYEGAHVHAGIRGTLESLIGKERIVELASGMIKENPSAGHAVAELCGHDFTRLSPRHLE
HAAKQGDPLSLALWQRVGEALGVGLANVTALMDIRKFVIGGGISAAGDLIITPAFERLRRSTLPSMHEGLDIVPAELGNR
AGMYGAAALCFV

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1786891, Length=259, Percent_Identity=28.1853281853282, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787878, Length=257, Percent_Identity=26.0700389105058, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787363, Length=320, Percent_Identity=29.375, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082230, Length=274, Percent_Identity=30.6569343065693, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082127, Length=175, Percent_Identity=24.5714285714286, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081733, Length=294, Percent_Identity=27.891156462585, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34607; Mature: 34607

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRDMFRWAIGIDLGGTAIKGAVIGEQEGIVTERTIPTDTASGPEGIVEQLAGLIAALKV
CCCCCEEEEEEECCCCCEEECEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
QGARFFDASGFAGTGLGAPGAVNVSLGTLSYPPNLPGWTVFPLCDALQNCLKEKENLSVS
CCCEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEE
VILENDANAAAFGEAMYGAGKHFSDFLMVTLGTGVGGGIILNRQLYRGANGTAGEVGFMI
EEEECCCCHHHHHHHHHCCCCCHHHEEEEEECCCCCCCEEEEHHHHCCCCCCCCCEEEEE
VDYEGAHVHAGIRGTLESLIGKERIVELASGMIKENPSAGHAVAELCGHDFTRLSPRHLE
EECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHCCCHHHHH
HAAKQGDPLSLALWQRVGEALGVGLANVTALMDIRKFVIGGGISAAGDLIITPAFERLRR
HHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHH
STLPSMHEGLDIVPAELGNRAGMYGAAALCFV
HCCCHHHCCCEEEHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MQRDMFRWAIGIDLGGTAIKGAVIGEQEGIVTERTIPTDTASGPEGIVEQLAGLIAALKV
CCCCCEEEEEEECCCCCEEECEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
QGARFFDASGFAGTGLGAPGAVNVSLGTLSYPPNLPGWTVFPLCDALQNCLKEKENLSVS
CCCEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEE
VILENDANAAAFGEAMYGAGKHFSDFLMVTLGTGVGGGIILNRQLYRGANGTAGEVGFMI
EEEECCCCHHHHHHHHHCCCCCHHHEEEEEECCCCCCCEEEEHHHHCCCCCCCCCEEEEE
VDYEGAHVHAGIRGTLESLIGKERIVELASGMIKENPSAGHAVAELCGHDFTRLSPRHLE
EECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHCCCHHHHH
HAAKQGDPLSLALWQRVGEALGVGLANVTALMDIRKFVIGGGISAAGDLIITPAFERLRR
HHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHH
STLPSMHEGLDIVPAELGNRAGMYGAAALCFV
HCCCHHHCCCEEEHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]