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The map label for this gene is queC

Identifier: 119357731

GI number: 119357731

Start: 2242472

End: 2243152

Strand: Reverse

Name: queC

Synonym: Cpha266_1935

Alternate gene names: 119357731

Gene position: 2243152-2242472 (Counterclockwise)

Preceding gene: 119357732

Following gene: 119357730

Centisome position: 71.58

GC content: 50.37

Gene sequence:

>681_bases
ATGAAAGCAGTAGTCCTTCTCAGTGGAGGTATGGACAGCCTTGTTACAACGGCTATAGCCAACGCGCAAGGCTTTGAGCT
TGCGGCTATGCATGTTAATTACGGGCAGCGGACGTGGCATAAAGAGCTTGAGGCCTTTCGTCTTATTGCCGATCACTATG
CTATAGGCGAACGGCTCGAAATCAATGCTGATTACCTGGCTCAGATCGGCGGTTCCTCTTTGACTGACTATTCCATGCCC
ATCAGCGGCGCTGATCTTCAGGGATTATCAATTCCAACCAGCTATGTCCCGTTCAGAAACGCGGGGTTTCTTTCAATGGC
GGTCAGTTGGGCGGAAGTTATCGGAGCTGAAAGGATATTTATCGGAGCGGTTGAAGAGGACTCCTCCGGGTATCCTGATT
GTCGTAAAGTGTTTTATGATGCCTTCAATGCTGTTATAGCTCTCGGAACAAAGCCTGAAACCAGTATCGCGATCATGACG
CCGCTTATCGAGATGCAGAAGTCGGAGATTGTTCGTAAAGGCATGGAACTCACGGCGCCGTTCGAATTGAGCTGGTCGTG
CTATAAAAGCGAAGGAAAGGCTTGTGGCGTCTGTGACAGTTGCGCGCTGAGGCTGAGGGCTTTTGAGCGGGCAGGCATGC
GAGACCCCATTGATTATGAACAGCGTCCTGACTATATTTGA

Upstream 100 bases:

>100_bases
TGAATCCAAAAGAATTGCATACCTTTGGGGAAATTAATTTCAGGCGACGGTAAAGCAGTCTGAATTATCCTGGTGCCTTC
ATGAACCTGATTCACTCCCT

Downstream 100 bases:

>100_bases
CGTGTTTCTTTTAGCTGACCTCTTTCGACCACCCAAACAACATATACAGAGAATTGCGTCCGATTAACTTAAAGCCTGTT
TACCCTTCATGAAACCTGTC

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKAVVLLSGGMDSLVTTAIANAQGFELAAMHVNYGQRTWHKELEAFRLIADHYAIGERLEINADYLAQIGGSSLTDYSMP
ISGADLQGLSIPTSYVPFRNAGFLSMAVSWAEVIGAERIFIGAVEEDSSGYPDCRKVFYDAFNAVIALGTKPETSIAIMT
PLIEMQKSEIVRKGMELTAPFELSWSCYKSEGKACGVCDSCALRLRAFERAGMRDPIDYEQRPDYI

Sequences:

>Translated_226_residues
MKAVVLLSGGMDSLVTTAIANAQGFELAAMHVNYGQRTWHKELEAFRLIADHYAIGERLEINADYLAQIGGSSLTDYSMP
ISGADLQGLSIPTSYVPFRNAGFLSMAVSWAEVIGAERIFIGAVEEDSSGYPDCRKVFYDAFNAVIALGTKPETSIAIMT
PLIEMQKSEIVRKGMELTAPFELSWSCYKSEGKACGVCDSCALRLRAFERAGMRDPIDYEQRPDYI
>Mature_226_residues
MKAVVLLSGGMDSLVTTAIANAQGFELAAMHVNYGQRTWHKELEAFRLIADHYAIGERLEINADYLAQIGGSSLTDYSMP
ISGADLQGLSIPTSYVPFRNAGFLSMAVSWAEVIGAERIFIGAVEEDSSGYPDCRKVFYDAFNAVIALGTKPETSIAIMT
PLIEMQKSEIVRKGMELTAPFELSWSCYKSEGKACGVCDSCALRLRAFERAGMRDPIDYEQRPDYI

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=208, Percent_Identity=33.1730769230769, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_CHLPD (A1BHS4)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912375.1
- ProteinModelPortal:   A1BHS4
- SMR:   A1BHS4
- STRING:   A1BHS4
- GeneID:   4570049
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_1935
- NMPDR:   fig|290317.7.peg.2041
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK637361
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24833; Mature: 24833

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVLLSGGMDSLVTTAIANAQGFELAAMHVNYGQRTWHKELEAFRLIADHYAIGERLE
CCEEEEEECCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEE
INADYLAQIGGSSLTDYSMPISGADLQGLSIPTSYVPFRNAGFLSMAVSWAEVIGAERIF
ECHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEE
IGAVEEDSSGYPDCRKVFYDAFNAVIALGTKPETSIAIMTPLIEMQKSEIVRKGMELTAP
EEEEECCCCCCHHHHHHHHHHHHHEEEECCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCC
FELSWSCYKSEGKACGVCDSCALRLRAFERAGMRDPIDYEQRPDYI
EEECCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKAVVLLSGGMDSLVTTAIANAQGFELAAMHVNYGQRTWHKELEAFRLIADHYAIGERLE
CCEEEEEECCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEE
INADYLAQIGGSSLTDYSMPISGADLQGLSIPTSYVPFRNAGFLSMAVSWAEVIGAERIF
ECHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEE
IGAVEEDSSGYPDCRKVFYDAFNAVIALGTKPETSIAIMTPLIEMQKSEIVRKGMELTAP
EEEEECCCCCCHHHHHHHHHHHHHEEEECCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCC
FELSWSCYKSEGKACGVCDSCALRLRAFERAGMRDPIDYEQRPDYI
EEECCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA