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The map label for this gene is rsbP [H]

Identifier: 119357629

GI number: 119357629

Start: 2090479

End: 2092161

Strand: Reverse

Name: rsbP [H]

Synonym: Cpha266_1833

Alternate gene names: 119357629

Gene position: 2092161-2090479 (Counterclockwise)

Preceding gene: 119357630

Following gene: 119357628

Centisome position: 66.76

GC content: 47.65

Gene sequence:

>1683_bases
ATGAAAAATATTGCTGATATAACGGTGCTTTTTGTTGATGATGAGGCTGATATTCTCAGCTCATTAAACAGGTTTCTGCG
CAGGGAGCCCTATAAAAAACTGTTTGCCGAAAACGGAAAGAAAGCTCTTTCGCTGCTCGAAGAACATGCTGTCGCTCTTG
TTGTTACGGATCTTCGCATGCCGGAAATGAACGGTCTGGAACTGATCAGTGCGGTCAAGGAGAGAAATCCTGATGTTATC
CGTCTGATATTGAGCGGATCGCAGGATTTTGATCAGATTATCGAATCCATCAATAAAGGCGAAGTATTCCGTTTTATCCC
CAAGCCTGTGGACCCTGATGCGTTCAGAAAAGTGCTGAATGATGCCATCGACTATTATTGTCTTAAAACAGAACGCGAAG
AGCTGTTTAATGAGCTGTCGATAAAAAACAGGGAGTTGACCAGGGCCAATGATGCACTCCGTGTTATGGCCGGAGATCTG
CAGAGGAGTGAGGAAAAGTTCCGCTCAATGACCGATGCCGCACATGACGCTGTTTTCATGCTTAACAATGAAGGGAAAAT
CGTTTATCGAAATACTGCGGCTGAAACGCTTTTTGGATTCAGCAGGGAAGAGTATGGTGATCAGCTTTTTTGGGAGCTGA
TCTCACCTGAATTTGCGGATTTCAATATTCATGATGTTTGCGAAATGATGCCGGACGAAGCTCTGCCTGATTTTAACAGT
GAAACAAGGGTTCGTCAAATCGAGGGTCTGAGAAAAGACGGCTCTCTGGTTCCGATTGAAATATCGAGAGGGTGTGTTCA
TATCGAGTCCGTTCATCATACGGTAGTTATTGCCAGGGATATCACAGCGCGCGTTGAGGCGGAGCGGAGCCGGGAGCGTT
ATGACAGCATGCAGAAAGAGCTTGAATCCGAGATTGAAAGAAAACTGCTGCAAAGCCCCGTTCCCGAAACCCTTCAGGGG
GTTTCAATCAGTCGCCTGATGATTCCTTCGGGTCATCTTGATGGAGATTTTACGGATTTTATTGTCTACAACAGCAGCCA
TGCCGACATAATTATTGGTGACGTCATGGGTCATGGCATTCAGTCGGCTCTGGTTGGCGCCGGTATAAAAGCACTGTTTC
TCAAGGCGATTGCACAAAAAAAGTGTCTGTATGGCGAACTCCCCGATCTGACGGGAGTCGTGAGCAGCGTTCATGATCTC
TGCATTCATGAGCTCATGGCACTCGGCACCTTTGCAACCCTTCTTTTCCTTCGTCTTGACCTTGAGGCGGGAGAGCTCTT
TCTGATCGACTGCGGTCACCCTCCGGTTCTTCACTTTAAGGACGCAACGGGAACCATTTCGATGCTCAAAGGCGAACAGT
TGCCGATCGGCATGATAGAGAGGCAGGATTACCATACCGTTTCAGCTTCGATCAGCGAGAACGATCTGCTTGTTCTCTAT
TCCGACGGTATTACCGAGAGTTTTTCGCCGGACGGGAGAATGTTCGGCACAGAACGACTGGTTGAACTGGTTATCAACTA
TCACGACCTGCCTGCGGAAGATCTGATTGAACACATCAAGGAGGGCGTTTCCTCTTTTGCCGGACGAGATACTTTTGATG
ATGATGTGACCTGTATCGTTATCCGTATCGGCACGTCGACTTATAAAACTGTTGCTGCGGGTAATCCTGGCGGCACACCG
TAA

Upstream 100 bases:

>100_bases
ATAAACATGGAGGAACTCTTGATGTTCATTGCCCGCCCGAGGGAGGTACCGTTATTACTCTTTCGCTTCCCCTGAGACAA
ATGACCGAAACGACAAACCC

Downstream 100 bases:

>100_bases
CCTGTATGCTTTTTACTTGATACCTGATGAACGCTTCTCTTTCAGAAAAAGCACGGCCAGTGTGTTCTACCATCGTTATT
ATCGGTGGCGGGCATAACCA

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MKNIADITVLFVDDEADILSSLNRFLRREPYKKLFAENGKKALSLLEEHAVALVVTDLRMPEMNGLELISAVKERNPDVI
RLILSGSQDFDQIIESINKGEVFRFIPKPVDPDAFRKVLNDAIDYYCLKTEREELFNELSIKNRELTRANDALRVMAGDL
QRSEEKFRSMTDAAHDAVFMLNNEGKIVYRNTAAETLFGFSREEYGDQLFWELISPEFADFNIHDVCEMMPDEALPDFNS
ETRVRQIEGLRKDGSLVPIEISRGCVHIESVHHTVVIARDITARVEAERSRERYDSMQKELESEIERKLLQSPVPETLQG
VSISRLMIPSGHLDGDFTDFIVYNSSHADIIIGDVMGHGIQSALVGAGIKALFLKAIAQKKCLYGELPDLTGVVSSVHDL
CIHELMALGTFATLLFLRLDLEAGELFLIDCGHPPVLHFKDATGTISMLKGEQLPIGMIERQDYHTVSASISENDLLVLY
SDGITESFSPDGRMFGTERLVELVINYHDLPAEDLIEHIKEGVSSFAGRDTFDDDVTCIVIRIGTSTYKTVAAGNPGGTP

Sequences:

>Translated_560_residues
MKNIADITVLFVDDEADILSSLNRFLRREPYKKLFAENGKKALSLLEEHAVALVVTDLRMPEMNGLELISAVKERNPDVI
RLILSGSQDFDQIIESINKGEVFRFIPKPVDPDAFRKVLNDAIDYYCLKTEREELFNELSIKNRELTRANDALRVMAGDL
QRSEEKFRSMTDAAHDAVFMLNNEGKIVYRNTAAETLFGFSREEYGDQLFWELISPEFADFNIHDVCEMMPDEALPDFNS
ETRVRQIEGLRKDGSLVPIEISRGCVHIESVHHTVVIARDITARVEAERSRERYDSMQKELESEIERKLLQSPVPETLQG
VSISRLMIPSGHLDGDFTDFIVYNSSHADIIIGDVMGHGIQSALVGAGIKALFLKAIAQKKCLYGELPDLTGVVSSVHDL
CIHELMALGTFATLLFLRLDLEAGELFLIDCGHPPVLHFKDATGTISMLKGEQLPIGMIERQDYHTVSASISENDLLVLY
SDGITESFSPDGRMFGTERLVELVINYHDLPAEDLIEHIKEGVSSFAGRDTFDDDVTCIVIRIGTSTYKTVAAGNPGGTP
>Mature_560_residues
MKNIADITVLFVDDEADILSSLNRFLRREPYKKLFAENGKKALSLLEEHAVALVVTDLRMPEMNGLELISAVKERNPDVI
RLILSGSQDFDQIIESINKGEVFRFIPKPVDPDAFRKVLNDAIDYYCLKTEREELFNELSIKNRELTRANDALRVMAGDL
QRSEEKFRSMTDAAHDAVFMLNNEGKIVYRNTAAETLFGFSREEYGDQLFWELISPEFADFNIHDVCEMMPDEALPDFNS
ETRVRQIEGLRKDGSLVPIEISRGCVHIESVHHTVVIARDITARVEAERSRERYDSMQKELESEIERKLLQSPVPETLQG
VSISRLMIPSGHLDGDFTDFIVYNSSHADIIIGDVMGHGIQSALVGAGIKALFLKAIAQKKCLYGELPDLTGVVSSVHDL
CIHELMALGTFATLLFLRLDLEAGELFLIDCGHPPVLHFKDATGTISMLKGEQLPIGMIERQDYHTVSASISENDLLVLY
SDGITESFSPDGRMFGTERLVELVINYHDLPAEDLIEHIKEGVSSFAGRDTFDDDVTCIVIRIGTSTYKTVAAGNPGGTP

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to energy stress [H]

COG id: COG3437

COG function: function code KT; Response regulator containing a CheY-like receiver domain and an HD-GYP domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=123, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790299, Length=118, Percent_Identity=31.3559322033898, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=29.1666666666667, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00989 PAS; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 62673; Mature: 62673

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIADITVLFVDDEADILSSLNRFLRREPYKKLFAENGKKALSLLEEHAVALVVTDLRM
CCCCCEEEEEEECCHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHCCEEEEEEECCC
PEMNGLELISAVKERNPDVIRLILSGSQDFDQIIESINKGEVFRFIPKPVDPDAFRKVLN
CCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
DAIDYYCLKTEREELFNELSIKNRELTRANDALRVMAGDLQRSEEKFRSMTDAAHDAVFM
HHHHHEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LNNEGKIVYRNTAAETLFGFSREEYGDQLFWELISPEFADFNIHDVCEMMPDEALPDFNS
EECCCCEEEECCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCC
ETRVRQIEGLRKDGSLVPIEISRGCVHIESVHHTVVIARDITARVEAERSRERYDSMQKE
CHHHHHHHCCCCCCCEEEEEECCCEEEEEECCEEEEEEECHHHHHHHHHHHHHHHHHHHH
LESEIERKLLQSPVPETLQGVSISRLMIPSGHLDGDFTDFIVYNSSHADIIIGDVMGHGI
HHHHHHHHHHHCCCCHHHCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEEHHHCCCH
QSALVGAGIKALFLKAIAQKKCLYGELPDLTGVVSSVHDLCIHELMALGTFATLLFLRLD
HHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LEAGELFLIDCGHPPVLHFKDATGTISMLKGEQLPIGMIERQDYHTVSASISENDLLVLY
CCCCCEEEEECCCCCEEEEECCCCEEEEECCCCCCCCEECCCCCEEEEEECCCCCEEEEE
SDGITESFSPDGRMFGTERLVELVINYHDLPAEDLIEHIKEGVSSFAGRDTFDDDVTCIV
ECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
IRIGTSTYKTVAAGNPGGTP
EEECCCCEEEEECCCCCCCC
>Mature Secondary Structure
MKNIADITVLFVDDEADILSSLNRFLRREPYKKLFAENGKKALSLLEEHAVALVVTDLRM
CCCCCEEEEEEECCHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHCCEEEEEEECCC
PEMNGLELISAVKERNPDVIRLILSGSQDFDQIIESINKGEVFRFIPKPVDPDAFRKVLN
CCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
DAIDYYCLKTEREELFNELSIKNRELTRANDALRVMAGDLQRSEEKFRSMTDAAHDAVFM
HHHHHEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LNNEGKIVYRNTAAETLFGFSREEYGDQLFWELISPEFADFNIHDVCEMMPDEALPDFNS
EECCCCEEEECCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCC
ETRVRQIEGLRKDGSLVPIEISRGCVHIESVHHTVVIARDITARVEAERSRERYDSMQKE
CHHHHHHHCCCCCCCEEEEEECCCEEEEEECCEEEEEEECHHHHHHHHHHHHHHHHHHHH
LESEIERKLLQSPVPETLQGVSISRLMIPSGHLDGDFTDFIVYNSSHADIIIGDVMGHGI
HHHHHHHHHHHCCCCHHHCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEEHHHCCCH
QSALVGAGIKALFLKAIAQKKCLYGELPDLTGVVSSVHDLCIHELMALGTFATLLFLRLD
HHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LEAGELFLIDCGHPPVLHFKDATGTISMLKGEQLPIGMIERQDYHTVSASISENDLLVLY
CCCCCEEEEECCCCCEEEEECCCCEEEEECCCCCCCCEECCCCCEEEEEECCCCCEEEEE
SDGITESFSPDGRMFGTERLVELVINYHDLPAEDLIEHIKEGVSSFAGRDTFDDDVTCIV
ECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
IRIGTSTYKTVAAGNPGGTP
EEECCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 10632888 [H]