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The map label for this gene is zraR [H]

Identifier: 119357628

GI number: 119357628

Start: 2089097

End: 2090452

Strand: Reverse

Name: zraR [H]

Synonym: Cpha266_1832

Alternate gene names: 119357628

Gene position: 2090452-2089097 (Counterclockwise)

Preceding gene: 119357629

Following gene: 119357627

Centisome position: 66.7

GC content: 47.64

Gene sequence:

>1356_bases
ATGAACGCTTCTCTTTCAGAAAAAGCACGGCCAGTGTGTTCTACCATCGTTATTATCGGTGGCGGGCATAACCAGCGGCC
TTTTGCGGTTTTGGGGGAAGATGGGTGTCAGGTGAGATGTCATTTTGCCGATAGCATTACAGCAGCGGAAACGTTGCTGG
ACACGGAAAAGGTTGATTTCATGCTTATAGCGCCAACCGGTCAGGATCAGGAGATTTTTTCATTTGCACGTCAGTTGCTG
CACAAAAACCGGGGGACAAAAATCTTTTTTTTCGGCAATGGTGATGAGTTATCAGCCATGCTGCGTTTTATTGAAAAGCT
TCAGCCGGAAGAACTCGGAAAACTGCTTTCGTCGCGACAGGCTTTTTCAACACCCGAGGAGCTTTCCGGGTGCATCGATG
CATCAGGAGATACACATCCGGCTGTTTTTTTCTTTGAGGGACTCATTGGTAATTCTCCTGAAATTCAGAAACTCAAGGAA
GTCGTACTCAAAATAGCGCCAACCTGTACGACTGTTCTGATTCAGGGCGAGAGCGGAACCGGCAAGGACGTTATTGCCCG
GGCAATCCATTTTCACAGCGCAAGGAAAAAAGAGGTTTTTATGCCGGTTGATTGTGCGGCAATCAATGAAAGTGTTATTG
AAAGCGAGCTGTTCGGCCATACGAAGGGTGCTTTTACCGGTGCAGACTGGAATACCCTCGGGCTGATTCGTTCGTCGGAC
AGGGGGTCTCTTTTTCTTGATGAAATTGCCGAACTCCCCATGCACTTGCAGGCCAAACTGCTTCGTACGCTTCAGGAGAG
GGCTGTAAAGCCTGTCGGGTCATCAACAATCTATCCTGTCGATATCAGGATTATATCCGCAAGCAACAGCAATCTGGCTG
AAGCGGTTAAAAAAGGTACTTTTCGTCAGGATCTCTATTACCGGATGAGTGCGGTTACCATTTATGCGCCGCCTTTGCGC
GAACGCCGTTCTGATATACCGCTTCTGTGCAGTTTCTTTATCAGAAAACTTGTAAAGGAGGGATTTCCGGAGAAAAGGTT
TTCTTCGCAAGCGATGGCAGCTTTATCCGGATTTGACTGGCCGGGTAACGTACGTGAGCTGGAAAATGTGATCAGATGTG
CGGTAACCCTTTCTCAGGGTACTATTATTGATCAGCCTGATCTGTCAATACCCTTATCCGGTTCAGATGATCTGTCAGTT
ACCGGTTGTGCTGAATCTTCAAGTATGGCTTTTCATGAAAAAGAGGCTATCCGAAAGGCGCTCAAAAAGACCATCGGCAA
CAGACGGGCTGCGGCAAAGTTGCTTGGCATCAGTGAAGCAACGTTGTATCGTCGGATCAAACTCTACAGTATATGA

Upstream 100 bases:

>100_bases
CCTGTATCGTTATCCGTATCGGCACGTCGACTTATAAAACTGTTGCTGCGGGTAATCCTGGCGGCACACCGTAACCTGTA
TGCTTTTTACTTGATACCTG

Downstream 100 bases:

>100_bases
TGTTTTTTCATGTGCATCGGGATAGAGTCGTGTCGCCAGCGCGTTGCTTCTATCGTAATCATTGTTTTCTCTCCGGCTGA
GAGAAGGGGTTTCATTGTTC

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MNASLSEKARPVCSTIVIIGGGHNQRPFAVLGEDGCQVRCHFADSITAAETLLDTEKVDFMLIAPTGQDQEIFSFARQLL
HKNRGTKIFFFGNGDELSAMLRFIEKLQPEELGKLLSSRQAFSTPEELSGCIDASGDTHPAVFFFEGLIGNSPEIQKLKE
VVLKIAPTCTTVLIQGESGTGKDVIARAIHFHSARKKEVFMPVDCAAINESVIESELFGHTKGAFTGADWNTLGLIRSSD
RGSLFLDEIAELPMHLQAKLLRTLQERAVKPVGSSTIYPVDIRIISASNSNLAEAVKKGTFRQDLYYRMSAVTIYAPPLR
ERRSDIPLLCSFFIRKLVKEGFPEKRFSSQAMAALSGFDWPGNVRELENVIRCAVTLSQGTIIDQPDLSIPLSGSDDLSV
TGCAESSSMAFHEKEAIRKALKKTIGNRRAAAKLLGISEATLYRRIKLYSI

Sequences:

>Translated_451_residues
MNASLSEKARPVCSTIVIIGGGHNQRPFAVLGEDGCQVRCHFADSITAAETLLDTEKVDFMLIAPTGQDQEIFSFARQLL
HKNRGTKIFFFGNGDELSAMLRFIEKLQPEELGKLLSSRQAFSTPEELSGCIDASGDTHPAVFFFEGLIGNSPEIQKLKE
VVLKIAPTCTTVLIQGESGTGKDVIARAIHFHSARKKEVFMPVDCAAINESVIESELFGHTKGAFTGADWNTLGLIRSSD
RGSLFLDEIAELPMHLQAKLLRTLQERAVKPVGSSTIYPVDIRIISASNSNLAEAVKKGTFRQDLYYRMSAVTIYAPPLR
ERRSDIPLLCSFFIRKLVKEGFPEKRFSSQAMAALSGFDWPGNVRELENVIRCAVTLSQGTIIDQPDLSIPLSGSDDLSV
TGCAESSSMAFHEKEAIRKALKKTIGNRRAAAKLLGISEATLYRRIKLYSI
>Mature_451_residues
MNASLSEKARPVCSTIVIIGGGHNQRPFAVLGEDGCQVRCHFADSITAAETLLDTEKVDFMLIAPTGQDQEIFSFARQLL
HKNRGTKIFFFGNGDELSAMLRFIEKLQPEELGKLLSSRQAFSTPEELSGCIDASGDTHPAVFFFEGLIGNSPEIQKLKE
VVLKIAPTCTTVLIQGESGTGKDVIARAIHFHSARKKEVFMPVDCAAINESVIESELFGHTKGAFTGADWNTLGLIRSSD
RGSLFLDEIAELPMHLQAKLLRTLQERAVKPVGSSTIYPVDIRIISASNSNLAEAVKKGTFRQDLYYRMSAVTIYAPPLR
ERRSDIPLLCSFFIRKLVKEGFPEKRFSSQAMAALSGFDWPGNVRELENVIRCAVTLSQGTIIDQPDLSIPLSGSDDLSV
TGCAESSSMAFHEKEAIRKALKKTIGNRRAAAKLLGISEATLYRRIKLYSI

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=308, Percent_Identity=46.1038961038961, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1788550, Length=312, Percent_Identity=43.9102564102564, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1789233, Length=322, Percent_Identity=42.2360248447205, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1788905, Length=307, Percent_Identity=40.0651465798046, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1789087, Length=313, Percent_Identity=39.9361022364217, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI87082117, Length=321, Percent_Identity=41.4330218068536, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1790299, Length=325, Percent_Identity=37.8461538461538, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1786524, Length=351, Percent_Identity=39.031339031339, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI87082152, Length=312, Percent_Identity=39.7435897435897, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87081872, Length=325, Percent_Identity=36.3076923076923, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1787583, Length=311, Percent_Identity=33.4405144694534, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI87081858, Length=316, Percent_Identity=31.9620253164557, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789828, Length=251, Percent_Identity=34.6613545816733, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49564; Mature: 49564

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASLSEKARPVCSTIVIIGGGHNQRPFAVLGEDGCQVRCHFADSITAAETLLDTEKVDF
CCCCCCHHCCCCEEEEEEEECCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCE
MLIAPTGQDQEIFSFARQLLHKNRGTKIFFFGNGDELSAMLRFIEKLQPEELGKLLSSRQ
EEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHH
AFSTPEELSGCIDASGDTHPAVFFFEGLIGNSPEIQKLKEVVLKIAPTCTTVLIQGESGT
CCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCC
GKDVIARAIHFHSARKKEVFMPVDCAAINESVIESELFGHTKGAFTGADWNTLGLIRSSD
CHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
RGSLFLDEIAELPMHLQAKLLRTLQERAVKPVGSSTIYPVDIRIISASNSNLAEAVKKGT
CCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHHCC
FRQDLYYRMSAVTIYAPPLRERRSDIPLLCSFFIRKLVKEGFPEKRFSSQAMAALSGFDW
HHHHHHHHEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
PGNVRELENVIRCAVTLSQGTIIDQPDLSIPLSGSDDLSVTGCAESSSMAFHEKEAIRKA
CCCHHHHHHHHHHHEEECCCEEECCCCCEEECCCCCCCEEEECCCCCCCHHHHHHHHHHH
LKKTIGNRRAAAKLLGISEATLYRRIKLYSI
HHHHHCCHHHHHHHHCCHHHHHHHHEEEECC
>Mature Secondary Structure
MNASLSEKARPVCSTIVIIGGGHNQRPFAVLGEDGCQVRCHFADSITAAETLLDTEKVDF
CCCCCCHHCCCCEEEEEEEECCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCE
MLIAPTGQDQEIFSFARQLLHKNRGTKIFFFGNGDELSAMLRFIEKLQPEELGKLLSSRQ
EEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHH
AFSTPEELSGCIDASGDTHPAVFFFEGLIGNSPEIQKLKEVVLKIAPTCTTVLIQGESGT
CCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCC
GKDVIARAIHFHSARKKEVFMPVDCAAINESVIESELFGHTKGAFTGADWNTLGLIRSSD
CHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
RGSLFLDEIAELPMHLQAKLLRTLQERAVKPVGSSTIYPVDIRIISASNSNLAEAVKKGT
CCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHHCC
FRQDLYYRMSAVTIYAPPLRERRSDIPLLCSFFIRKLVKEGFPEKRFSSQAMAALSGFDW
HHHHHHHHEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
PGNVRELENVIRCAVTLSQGTIIDQPDLSIPLSGSDDLSVTGCAESSSMAFHEKEAIRKA
CCCHHHHHHHHHHHEEECCCEEECCCCCEEECCCCCCCEEEECCCCCCCHHHHHHHHHHH
LKKTIGNRRAAAKLLGISEATLYRRIKLYSI
HHHHHCCHHHHHHHHCCHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]