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The map label for this gene is rsmB [H]

Identifier: 119357565

GI number: 119357565

Start: 2010117

End: 2011451

Strand: Direct

Name: rsmB [H]

Synonym: Cpha266_1768

Alternate gene names: 119357565

Gene position: 2010117-2011451 (Clockwise)

Preceding gene: 119357562

Following gene: 119357566

Centisome position: 64.14

GC content: 49.36

Gene sequence:

>1335_bases
ATGAATGCAAGAGAAGCTGCCCTCAAGGCGCTGCAGGCTATTGAACCCGGCAAGGAAAAATCAGACCGGATAGTACACGC
AATACTCGACAGGGCAACAATGAACAGGCAAGACCGGGCTCTGACAACTGAACTGGTCAACGGTGTCCTGCGAATGCGCA
AAAAAATCGATTTTATTATTTCGAAATTCTATCATCATCGCTTTGAAAAAGCAGCACCTGTTCTACAGAATATCCTGCGA
CTTGGCGTCTATCAACTGCTCTTTCTGGAAAAAATCCCGGAATGGGCCGCAGTCAGTGAATGTGTGGATCTTGCAAGAAA
GTACAAAGGCGAGCGGATGGCAAAACTTGTCAACGGTGTCTTGAGAAAAATCACCCCTGATAACGTCGTTATGGACGAGT
GGCTGAAAGGTTGTGAGGATATGGAACGACTATCGGTGCAATACTCCCATCCAGAGTGGCTCATCAATCGATGGAACGCT
GTTTATGGCAGAGAAACCACGCTTGCTTCCATGACCTATAACAACCATGCCCCCCTTTTTGGATTCAGAATCAACACACT
GAAACAAACGCCTGATGAATTCCTTGCCGATCCAGCACATTCGTCCTTTCCTCAAGAGCGGTGCTTGACAGGTAATTTTT
TCCTTTCAAAGGAGTTTGCCGGATTTGAGGCCTGCCTGAAATCGGGAAAACTGACCGTTCAGAATCCGACGCAGGGAGTT
GCATGCCTGCTGCTCAACCCCGTACCAGAAAGCAGGGTCCTTGATCTGTGTGCGGCACCGGGCGGCAAAGCCACGTTCAT
GGCTGAGCTCATGCAGAACAAAGGTTCAATCACAGCAGTTGACCGATCGAGCGAAAAACTCGAAAAAACCAGGCAACATG
CTGTTGAACTCGGCATAACAATCATCAAAACAATCTGCGCCGATGCCCGGTCATTTGTCCCGGAAGAGACACCACAAGCC
GTTCTTCTCGATGCGCCCTGTACAGGAACCGGCGTTTTGCAGAAACGTGCCGAACTCCGATGGAAACTCTCAATGGAGAT
GCTACAGGAACTGGTAACGCTCCAGAGGGAATTGCTTGACCATGCAGCTTCGATATTGCCGGTAAACGGTATTCTGCTCT
ATGCAACCTGTTCGATAGAACCGGAAGAAAATGAGTTGCAAATAGAGGCTTTTCTGCGTCGTCATCCTGAATTTTCAAGA
GACACCTCTTGCGGCTCTCTCCCTGAACCGTTCAGGATGAGCGCGGCTGAAAAGGGTTCCATCCTTACCCTTCCGGGCGA
GCTTCCAGGATTTGACGGGGGATTTGCTCAACGGTTACGAAAAAACGCACGGTAA

Upstream 100 bases:

>100_bases
TATTAAAAAGAACATTTATTGCCATTAATCTACAACAGGGAATAGTATTTTACAAGTCAACTTCCCTGCAAGAGCGCAGG
AAATCTATTTTTATGACCTC

Downstream 100 bases:

>100_bases
CCATGGAGCATCTCCATACACCCTACTCGATCTATCTTGAGAATTTTCTGAACCATCTGTTGATCGAACGTAATTTCTCG
CAGAATACGAGAGTATCGTA

Product: sun protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MNAREAALKALQAIEPGKEKSDRIVHAILDRATMNRQDRALTTELVNGVLRMRKKIDFIISKFYHHRFEKAAPVLQNILR
LGVYQLLFLEKIPEWAAVSECVDLARKYKGERMAKLVNGVLRKITPDNVVMDEWLKGCEDMERLSVQYSHPEWLINRWNA
VYGRETTLASMTYNNHAPLFGFRINTLKQTPDEFLADPAHSSFPQERCLTGNFFLSKEFAGFEACLKSGKLTVQNPTQGV
ACLLLNPVPESRVLDLCAAPGGKATFMAELMQNKGSITAVDRSSEKLEKTRQHAVELGITIIKTICADARSFVPEETPQA
VLLDAPCTGTGVLQKRAELRWKLSMEMLQELVTLQRELLDHAASILPVNGILLYATCSIEPEENELQIEAFLRRHPEFSR
DTSCGSLPEPFRMSAAEKGSILTLPGELPGFDGGFAQRLRKNAR

Sequences:

>Translated_444_residues
MNAREAALKALQAIEPGKEKSDRIVHAILDRATMNRQDRALTTELVNGVLRMRKKIDFIISKFYHHRFEKAAPVLQNILR
LGVYQLLFLEKIPEWAAVSECVDLARKYKGERMAKLVNGVLRKITPDNVVMDEWLKGCEDMERLSVQYSHPEWLINRWNA
VYGRETTLASMTYNNHAPLFGFRINTLKQTPDEFLADPAHSSFPQERCLTGNFFLSKEFAGFEACLKSGKLTVQNPTQGV
ACLLLNPVPESRVLDLCAAPGGKATFMAELMQNKGSITAVDRSSEKLEKTRQHAVELGITIIKTICADARSFVPEETPQA
VLLDAPCTGTGVLQKRAELRWKLSMEMLQELVTLQRELLDHAASILPVNGILLYATCSIEPEENELQIEAFLRRHPEFSR
DTSCGSLPEPFRMSAAEKGSILTLPGELPGFDGGFAQRLRKNAR
>Mature_444_residues
MNAREAALKALQAIEPGKEKSDRIVHAILDRATMNRQDRALTTELVNGVLRMRKKIDFIISKFYHHRFEKAAPVLQNILR
LGVYQLLFLEKIPEWAAVSECVDLARKYKGERMAKLVNGVLRKITPDNVVMDEWLKGCEDMERLSVQYSHPEWLINRWNA
VYGRETTLASMTYNNHAPLFGFRINTLKQTPDEFLADPAHSSFPQERCLTGNFFLSKEFAGFEACLKSGKLTVQNPTQGV
ACLLLNPVPESRVLDLCAAPGGKATFMAELMQNKGSITAVDRSSEKLEKTRQHAVELGITIIKTICADARSFVPEETPQA
VLLDAPCTGTGVLQKRAELRWKLSMEMLQELVTLQRELLDHAASILPVNGILLYATCSIEPEENELQIEAFLRRHPEFSR
DTSCGSLPEPFRMSAAEKGSILTLPGELPGFDGGFAQRLRKNAR

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=181, Percent_Identity=35.9116022099448, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI76150625, Length=177, Percent_Identity=34.4632768361582, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI76150623, Length=177, Percent_Identity=34.4632768361582, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI8922322, Length=241, Percent_Identity=29.045643153527, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI270288818, Length=241, Percent_Identity=29.045643153527, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI270288816, Length=241, Percent_Identity=29.045643153527, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI23199998, Length=241, Percent_Identity=29.045643153527, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI301336155, Length=230, Percent_Identity=25.6521739130435, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI39995082, Length=185, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI2367212, Length=404, Percent_Identity=31.4356435643564, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI87081985, Length=272, Percent_Identity=31.6176470588235, Blast_Score=101, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17536757, Length=172, Percent_Identity=36.046511627907, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71998419, Length=167, Percent_Identity=32.3353293413174, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115534021, Length=167, Percent_Identity=32.3353293413174, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25143471, Length=178, Percent_Identity=30.3370786516854, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=179, Percent_Identity=31.2849162011173, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319447, Length=212, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI22024126, Length=167, Percent_Identity=36.5269461077844, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21356579, Length=175, Percent_Identity=32.5714285714286, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24668781, Length=185, Percent_Identity=31.8918918918919, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356513, Length=185, Percent_Identity=31.8918918918919, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355201, Length=185, Percent_Identity=24.8648648648649, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 49867; Mature: 49867

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAREAALKALQAIEPGKEKSDRIVHAILDRATMNRQDRALTTELVNGVLRMRKKIDFII
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKFYHHRFEKAAPVLQNILRLGVYQLLFLEKIPEWAAVSECVDLARKYKGERMAKLVNGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHH
LRKITPDNVVMDEWLKGCEDMERLSVQYSHPEWLINRWNAVYGRETTLASMTYNNHAPLF
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
GFRINTLKQTPDEFLADPAHSSFPQERCLTGNFFLSKEFAGFEACLKSGKLTVQNPTQGV
EEEEHHHHCCCHHHHCCCCCCCCCHHHCCCCCEEECHHHHHHHHHHHCCCEEEECCCCCE
ACLLLNPVPESRVLDLCAAPGGKATFMAELMQNKGSITAVDRSSEKLEKTRQHAVELGIT
EEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
IIKTICADARSFVPEETPQAVLLDAPCTGTGVLQKRAELRWKLSMEMLQELVTLQRELLD
HHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAASILPVNGILLYATCSIEPEENELQIEAFLRRHPEFSRDTSCGSLPEPFRMSAAEKGS
HHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCC
ILTLPGELPGFDGGFAQRLRKNAR
EEECCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MNAREAALKALQAIEPGKEKSDRIVHAILDRATMNRQDRALTTELVNGVLRMRKKIDFII
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKFYHHRFEKAAPVLQNILRLGVYQLLFLEKIPEWAAVSECVDLARKYKGERMAKLVNGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHH
LRKITPDNVVMDEWLKGCEDMERLSVQYSHPEWLINRWNAVYGRETTLASMTYNNHAPLF
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
GFRINTLKQTPDEFLADPAHSSFPQERCLTGNFFLSKEFAGFEACLKSGKLTVQNPTQGV
EEEEHHHHCCCHHHHCCCCCCCCCHHHCCCCCEEECHHHHHHHHHHHCCCEEEECCCCCE
ACLLLNPVPESRVLDLCAAPGGKATFMAELMQNKGSITAVDRSSEKLEKTRQHAVELGIT
EEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
IIKTICADARSFVPEETPQAVLLDAPCTGTGVLQKRAELRWKLSMEMLQELVTLQRELLD
HHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAASILPVNGILLYATCSIEPEENELQIEAFLRRHPEFSRDTSCGSLPEPFRMSAAEKGS
HHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCC
ILTLPGELPGFDGGFAQRLRKNAR
EEECCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]