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The map label for this gene is xerD [H]

Identifier: 119357566

GI number: 119357566

Start: 2011454

End: 2012368

Strand: Direct

Name: xerD [H]

Synonym: Cpha266_1769

Alternate gene names: 119357566

Gene position: 2011454-2012368 (Clockwise)

Preceding gene: 119357565

Following gene: 119357575

Centisome position: 64.18

GC content: 48.52

Gene sequence:

>915_bases
ATGGAGCATCTCCATACACCCTACTCGATCTATCTTGAGAATTTTCTGAACCATCTGTTGATCGAACGTAATTTCTCGCA
GAATACGAGAGTATCGTATCGCAACGACCTTCATCGCTACCTGCTCACCGTGCAGGAAACCATGAAGCCGATTACCTCTG
TCACAGCCTCCGATATCCGACAGTTTATCAGTGAACTGCACGAAACAGGACTTGAGCCCGCAACCATTGCGCGAAACATA
TCCGCAATTCGTTCCCTGTTCCGGTTTCTCGTCATCGAACATCTGCTTGAGGCAAATCCCGCTGAAAACATTCATCAGCC
TAAACAGGCAAAAAACCTGCCCTCAGTCCTGACGATTGAAGAGACTCTCCGGCTGCTCGAAGCTCCGATCCTGCAACATC
CTCCGGGAAAATATCTCCTGCGGGACAAGGCTATCCTTGAATTTCTTTATGCAACCGGTGTAAGGGTAAGCGAATTGACT
GAATTGCAGCAGCAAAGCCTTTTTCTTGAAGCTGGCTTTGTGAGAATACTGGGTAAAGGATCGAAAGAGCGTCTTGTCCC
GATCGGTCTCTCGGCCATAAACAGCATCAACAGGTACCGAACCGAACTGCGTATCGGCCTCATCAACAGAAACTCGCAGG
ACTACGTATTCCTGAATGCAAGAGGAAAAAAACTCTCCCGCATGGCAATCTACTCGATGGTGCAGGAGTATGCCTCACTC
AGCGGTATAGAAAAAAAAATAAGCCCTCATACACTCCGCCATACCTTTGCAACGCATCTGCTGGAGGGCGGAGCGGATTT
AAGAGCCGTTCAGGAGATGCTTGGACACAGTTCCATCCTCGCAACGCAACTCTACACCCATATTGACCGCTCTTTTATCA
AGGAGGTCCATAAAACGTTTCATCCGAGAGGTTAA

Upstream 100 bases:

>100_bases
TGAGCGCGGCTGAAAAGGGTTCCATCCTTACCCTTCCGGGCGAGCTTCCAGGATTTGACGGGGGATTTGCTCAACGGTTA
CGAAAAAACGCACGGTAACC

Downstream 100 bases:

>100_bases
GAACTCAGCGATTCGGTTCGTATTTTTTAAGCCACTCAATAGCCTCAGGGTTTTCCTTTTCAGCCGCAACCCGAATGTCT
TTCATCGCTCCCAAGGTATC

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MEHLHTPYSIYLENFLNHLLIERNFSQNTRVSYRNDLHRYLLTVQETMKPITSVTASDIRQFISELHETGLEPATIARNI
SAIRSLFRFLVIEHLLEANPAENIHQPKQAKNLPSVLTIEETLRLLEAPILQHPPGKYLLRDKAILEFLYATGVRVSELT
ELQQQSLFLEAGFVRILGKGSKERLVPIGLSAINSINRYRTELRIGLINRNSQDYVFLNARGKKLSRMAIYSMVQEYASL
SGIEKKISPHTLRHTFATHLLEGGADLRAVQEMLGHSSILATQLYTHIDRSFIKEVHKTFHPRG

Sequences:

>Translated_304_residues
MEHLHTPYSIYLENFLNHLLIERNFSQNTRVSYRNDLHRYLLTVQETMKPITSVTASDIRQFISELHETGLEPATIARNI
SAIRSLFRFLVIEHLLEANPAENIHQPKQAKNLPSVLTIEETLRLLEAPILQHPPGKYLLRDKAILEFLYATGVRVSELT
ELQQQSLFLEAGFVRILGKGSKERLVPIGLSAINSINRYRTELRIGLINRNSQDYVFLNARGKKLSRMAIYSMVQEYASL
SGIEKKISPHTLRHTFATHLLEGGADLRAVQEMLGHSSILATQLYTHIDRSFIKEVHKTFHPRG
>Mature_304_residues
MEHLHTPYSIYLENFLNHLLIERNFSQNTRVSYRNDLHRYLLTVQETMKPITSVTASDIRQFISELHETGLEPATIARNI
SAIRSLFRFLVIEHLLEANPAENIHQPKQAKNLPSVLTIEETLRLLEAPILQHPPGKYLLRDKAILEFLYATGVRVSELT
ELQQQSLFLEAGFVRILGKGSKERLVPIGLSAINSINRYRTELRIGLINRNSQDYVFLNARGKKLSRMAIYSMVQEYASL
SGIEKKISPHTLRHTFATHLLEGGADLRAVQEMLGHSSILATQLYTHIDRSFIKEVHKTFHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=40.1360544217687, Blast_Score=224, Evalue=5e-60,
Organism=Escherichia coli, GI1790244, Length=305, Percent_Identity=35.4098360655738, Blast_Score=190, Evalue=8e-50,
Organism=Escherichia coli, GI1790768, Length=171, Percent_Identity=30.4093567251462, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34826; Mature: 34826

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHLHTPYSIYLENFLNHLLIERNFSQNTRVSYRNDLHRYLLTVQETMKPITSVTASDIR
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFISELHETGLEPATIARNISAIRSLFRFLVIEHLLEANPAENIHQPKQAKNLPSVLTIE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHCCCCCEEEHH
ETLRLLEAPILQHPPGKYLLRDKAILEFLYATGVRVSELTELQQQSLFLEAGFVRILGKG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SKERLVPIGLSAINSINRYRTELRIGLINRNSQDYVFLNARGKKLSRMAIYSMVQEYASL
CCCCEEEHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
SGIEKKISPHTLRHTFATHLLEGGADLRAVQEMLGHSSILATQLYTHIDRSFIKEVHKTF
HHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
HPRG
CCCC
>Mature Secondary Structure
MEHLHTPYSIYLENFLNHLLIERNFSQNTRVSYRNDLHRYLLTVQETMKPITSVTASDIR
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFISELHETGLEPATIARNISAIRSLFRFLVIEHLLEANPAENIHQPKQAKNLPSVLTIE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHCCCCCEEEHH
ETLRLLEAPILQHPPGKYLLRDKAILEFLYATGVRVSELTELQQQSLFLEAGFVRILGKG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SKERLVPIGLSAINSINRYRTELRIGLINRNSQDYVFLNARGKKLSRMAIYSMVQEYASL
CCCCEEEHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
SGIEKKISPHTLRHTFATHLLEGGADLRAVQEMLGHSSILATQLYTHIDRSFIKEVHKTF
HHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
HPRG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]