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The map label for this gene is 119357368

Identifier: 119357368

GI number: 119357368

Start: 1780578

End: 1782587

Strand: Reverse

Name: 119357368

Synonym: Cpha266_1566

Alternate gene names: NA

Gene position: 1782587-1780578 (Counterclockwise)

Preceding gene: 119357369

Following gene: 119357367

Centisome position: 56.88

GC content: 48.21

Gene sequence:

>2010_bases
ATGATACGATGGAGCCGTTACCGATGGCTTTCTATTGGTTTTTTGTTCTGCTTTGTTTGGTTCAAGAGCGTGTCGGCTGA
AACGGGTTCTTCTCTGCCGCCTGATAAGAGTCCTTTGGCTTCGGACTCTTCAATCTTTTTGAATACCAGCAAAGGGAGTT
TATCCGATTTTTTACAGTCGTCTCAAAAAACAACAGTTCAAAAAGAGTCGCTTAAGAGCAGAGGGTATTATCTGCAACTT
ATGGATACGATGAGGAGTGATGCAGGGGCGCGGCAGCCGGTTGATAACCCTGATAAGATGCTGTTTCATGATCGTATCAG
TGATAGCGTCGGGCAGATGGTTAAAAACCCGCAAACAACGAGTCGCACAAAGCAGCAGTCACTGAGGAAAAAGCAGGTGA
AGGACAGTCTTGTGATGGATTCGAGAAAGAAATCGCAAGAATTACGGCAGCAAAAGGAACGGCTTCGCAAAAGGGTGCTT
GACAGCCTTAACAATACGGTAATGAAGGCCCGGTTGCAGGACAGCATCAGTCAGGTTGTGCGGATACAGCGTTACAAGGA
TAGTCTGCGGCAGGCGACTCTGAAGGAGCGAGAGCGAGACAGTCTGAAAATGGCGGCCTTGATGCAGAAGAGTGACGCCG
TTTTGAGGCAGCGTGAGAGGCGAAAACAGCTACGGGACAGTCTGAGGGAGGCAGAGAAAAAGAACTCTCAACACACCCTC
TTTCGGCAAGGCGGCGCCCAGACAACACGCAATAGCGCACAGGCACTTCAGCAGGAACGTGTACATGAGGTAACGAGCAA
AATATCTCGTCAGGAAGTCGTCGCTATCTCTGCGGGAGCAGTTCCATCAGTTCAGACGCTCTCGGCAAAGAGCAGCGCAA
AGAGAAGGCTTGATAGCCTCAGTGCTGTCGCGGCTGATTTTTACGGTCGGGGTCTTTATGCTAATGCGCTGGTTCCGGCA
AAACAGGCTCTTTTGCTTGCCAGAAAAGTTCATGGCACGAATTCCGCCGGTGAAGCCGCTTCAATGGTGAGGCTTGCCGA
TAACTATCGCTCGATGAAACAGTACAATGCGGCGGAACTGCTCTATAATCGGGCTCTTGCTATCACCCAAAACATATCGG
GCGTTTGGCACAGGGATGCCGGTTTGCTTCTTTACACCCTTGCCAGACTCTCTTTCGAGCAGCAGCAATATCAGCTTGCC
GAGCAGTACTTCAGGCAGGCATTGTCTGTCAGAGAAAAAGAAGAAGGTGTTGACGGGCCGGGCGTTGTCGATATAGTCTA
TGATATGGGCCAGCTCTATCATCGTCTTCAAAATTATAATGCGGCTCTTCTGTACTACAGCAGATTATTGGCCATTCGGG
AAAAGTCTGTCAGGGCAGACGATCTGGAATTTGCTGCAATGTTATATTCTATCGCGGATCTTTATGCTGCTATCGGTCAG
TTTGACGTTGCTGCTGATTTTTTTCAGCGTTCACTTGATATCCGTGAAAAACTGTCCGGGCCATCACATCCCGATGTAGC
ATTCTCAATGAACGGTCTTGCAATGGTTTACCAGAAGCAACGACAGTATACCGTTGCCGAGTTGCTGTATAAGCGTTCGC
TTGCCATTCAGGAGCAGACTTTTGGGCCTGCACATCCTGAAGTTGCCGTTACGTTGCAGAGTCTGGCTTCGGTATGCAGG
TTTCAGAAGAAATATGATGCGGCAGAGCACTACATCAAGCGTTCCGTCGAGATCACAGAAAAGAACTTTCCCGCAACCCA
CCTGAATGTTGCAAAGTCCCTGAATTCGATGGCTTTGCTTTACCTTGAACTGGGAAACTTCGGAGTTGCCGAGCCGTTAT
TTAAAAGAGCATTGGCAATATCTGAAAAGAAACTTGGTGCATACCATACAGATCTTGCCCAGGTTCTTGAAAATATGGCG
TTGATGTATGAAAAAATGGATCGAAAAAAACAGGCTGAATCTTTTGCAAAAAGAGCAGAACGGATTCGTGAACTGGCAGA
CAATGATTGA

Upstream 100 bases:

>100_bases
TTTCTCCGATTCATTCCGATGCCGGAAATTTCTCTCTCTTTCAGTTATAAGTGATTTTGTTTGTTATTGATATTGTTTCA
CGACCATGAAATGTATTCAA

Downstream 100 bases:

>100_bases
GTGAAAATCAATTCGCTTCTTATGGTCAGAGGAAATGTGATACGTGACTTTACATCGCTCTCAAGTTTGTCAAAGCGCTT
TGAGGTCAAGGCGGACGGAG

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: Tetratricopeptide TPR_2 Repeat Protein; Tetratricopeptide Repeat Family; Tetratricopeptide Repeat Family Protein; Kinesin Light Chain; NB-ARC Domain-Containing Protein; Tetratricopeptide Domain-Containing Protein; NB-ARC Domain Protein; Serine/Threonine Protein Kinase; Tetratricopeptide Repeat Domain Protein; Serine/Threonine Kinase Family Protein; Nb-Arc; TPR Domain-Containing Protein; Tetratricopeptide Protein; TPR Domain Family Protein; SEC-C Motif Domain Protein; Tetratricopeptide TPR2 Protein; Serine/Threonine Protein Kinase With TPR Repeats; Tetratricopeptide Tpr_3 Repeat-Containing Protein; Tetratricopeptide Repeat-Containing Protein; TPR Repeat-Containing Serine/Threonin Protein Kinase; Protein Kinase; Sel1 Domain-Containing Protein; Ankyrin And Tpr Repeat Domain Protein; Peptidase-Like

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MIRWSRYRWLSIGFLFCFVWFKSVSAETGSSLPPDKSPLASDSSIFLNTSKGSLSDFLQSSQKTTVQKESLKSRGYYLQL
MDTMRSDAGARQPVDNPDKMLFHDRISDSVGQMVKNPQTTSRTKQQSLRKKQVKDSLVMDSRKKSQELRQQKERLRKRVL
DSLNNTVMKARLQDSISQVVRIQRYKDSLRQATLKERERDSLKMAALMQKSDAVLRQRERRKQLRDSLREAEKKNSQHTL
FRQGGAQTTRNSAQALQQERVHEVTSKISRQEVVAISAGAVPSVQTLSAKSSAKRRLDSLSAVAADFYGRGLYANALVPA
KQALLLARKVHGTNSAGEAASMVRLADNYRSMKQYNAAELLYNRALAITQNISGVWHRDAGLLLYTLARLSFEQQQYQLA
EQYFRQALSVREKEEGVDGPGVVDIVYDMGQLYHRLQNYNAALLYYSRLLAIREKSVRADDLEFAAMLYSIADLYAAIGQ
FDVAADFFQRSLDIREKLSGPSHPDVAFSMNGLAMVYQKQRQYTVAELLYKRSLAIQEQTFGPAHPEVAVTLQSLASVCR
FQKKYDAAEHYIKRSVEITEKNFPATHLNVAKSLNSMALLYLELGNFGVAEPLFKRALAISEKKLGAYHTDLAQVLENMA
LMYEKMDRKKQAESFAKRAERIRELADND

Sequences:

>Translated_669_residues
MIRWSRYRWLSIGFLFCFVWFKSVSAETGSSLPPDKSPLASDSSIFLNTSKGSLSDFLQSSQKTTVQKESLKSRGYYLQL
MDTMRSDAGARQPVDNPDKMLFHDRISDSVGQMVKNPQTTSRTKQQSLRKKQVKDSLVMDSRKKSQELRQQKERLRKRVL
DSLNNTVMKARLQDSISQVVRIQRYKDSLRQATLKERERDSLKMAALMQKSDAVLRQRERRKQLRDSLREAEKKNSQHTL
FRQGGAQTTRNSAQALQQERVHEVTSKISRQEVVAISAGAVPSVQTLSAKSSAKRRLDSLSAVAADFYGRGLYANALVPA
KQALLLARKVHGTNSAGEAASMVRLADNYRSMKQYNAAELLYNRALAITQNISGVWHRDAGLLLYTLARLSFEQQQYQLA
EQYFRQALSVREKEEGVDGPGVVDIVYDMGQLYHRLQNYNAALLYYSRLLAIREKSVRADDLEFAAMLYSIADLYAAIGQ
FDVAADFFQRSLDIREKLSGPSHPDVAFSMNGLAMVYQKQRQYTVAELLYKRSLAIQEQTFGPAHPEVAVTLQSLASVCR
FQKKYDAAEHYIKRSVEITEKNFPATHLNVAKSLNSMALLYLELGNFGVAEPLFKRALAISEKKLGAYHTDLAQVLENMA
LMYEKMDRKKQAESFAKRAERIRELADND
>Mature_669_residues
MIRWSRYRWLSIGFLFCFVWFKSVSAETGSSLPPDKSPLASDSSIFLNTSKGSLSDFLQSSQKTTVQKESLKSRGYYLQL
MDTMRSDAGARQPVDNPDKMLFHDRISDSVGQMVKNPQTTSRTKQQSLRKKQVKDSLVMDSRKKSQELRQQKERLRKRVL
DSLNNTVMKARLQDSISQVVRIQRYKDSLRQATLKERERDSLKMAALMQKSDAVLRQRERRKQLRDSLREAEKKNSQHTL
FRQGGAQTTRNSAQALQQERVHEVTSKISRQEVVAISAGAVPSVQTLSAKSSAKRRLDSLSAVAADFYGRGLYANALVPA
KQALLLARKVHGTNSAGEAASMVRLADNYRSMKQYNAAELLYNRALAITQNISGVWHRDAGLLLYTLARLSFEQQQYQLA
EQYFRQALSVREKEEGVDGPGVVDIVYDMGQLYHRLQNYNAALLYYSRLLAIREKSVRADDLEFAAMLYSIADLYAAIGQ
FDVAADFFQRSLDIREKLSGPSHPDVAFSMNGLAMVYQKQRQYTVAELLYKRSLAIQEQTFGPAHPEVAVTLQSLASVCR
FQKKYDAAEHYIKRSVEITEKNFPATHLNVAKSLNSMALLYLELGNFGVAEPLFKRALAISEKKLGAYHTDLAQVLENMA
LMYEKMDRKKQAESFAKRAERIRELADND

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI34304360, Length=376, Percent_Identity=33.2446808510638, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI41871955, Length=198, Percent_Identity=39.3939393939394, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI41871946, Length=198, Percent_Identity=39.3939393939394, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI41871960, Length=198, Percent_Identity=39.3939393939394, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI194306559, Length=198, Percent_Identity=40.4040404040404, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI110735431, Length=198, Percent_Identity=40.4040404040404, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI33620730, Length=198, Percent_Identity=40.4040404040404, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI91825557, Length=198, Percent_Identity=39.3939393939394, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI198041734, Length=198, Percent_Identity=38.3838383838384, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI198041731, Length=198, Percent_Identity=38.3838383838384, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI12383062, Length=198, Percent_Identity=38.3838383838384, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI198041728, Length=198, Percent_Identity=38.3838383838384, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI19923891, Length=91, Percent_Identity=40.6593406593407, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71984535, Length=199, Percent_Identity=38.6934673366834, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71984527, Length=199, Percent_Identity=38.6934673366834, Blast_Score=129, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71984517, Length=199, Percent_Identity=38.6934673366834, Blast_Score=129, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI71984524, Length=191, Percent_Identity=38.7434554973822, Blast_Score=128, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17541458, Length=158, Percent_Identity=36.0759493670886, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI17647555, Length=199, Percent_Identity=38.6934673366834, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 76008; Mature: 76008

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCC
>Mature Secondary Structure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HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA