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The map label for this gene is lolC [H]

Identifier: 119357127

GI number: 119357127

Start: 1507411

End: 1508661

Strand: Reverse

Name: lolC [H]

Synonym: Cpha266_1316

Alternate gene names: 119357127

Gene position: 1508661-1507411 (Counterclockwise)

Preceding gene: 119357128

Following gene: 119357124

Centisome position: 48.14

GC content: 50.12

Gene sequence:

>1251_bases
ATGAATATCGCTTTATGGATTGCCCGTCGTTTCAGTTTTGCCCGTAAACGATTCAGGGTTGTCAATGTCATTTCGGCTAT
CAGTCTTGCCGGGATTATCGTCGGGGTCTGCACGTTGCTTGTTGTGATGAGTGTGCTGAACGGTTTTCAGAAGCTTGCCT
GGGATCTTTTCGTCACGCTTGACAGCCCCGTTCAGATTGTTCCAAAAACCGGCAGAAGCATGACGATAAGCCCTCAACTT
CTGCACTCGATTGCTGCGCTTCAGGGGGTGTCGTCCGTTGAGCCTTTTCTTGAAGGTGAAGCGGTTCTTGTCGGATCCGA
AAAAAGTGAACTGGTCATGATAAAAGGTCTGAGCGAGGGAGCGCATAACCGACTGGTGAAGGTTACCCGCTCTTCGGCTC
CTTTCTTTACCGGTGATAACGTGAGCGTGGGGGAGCAGCTCGCCTATCGTACAGAGCTTCGTCCGTTCAGCGAGATATCG
CTTTTCAGTCCGGAACTTGTCGCCATCGGTCTTGAGTCGCTTTCGGAACCATATCTTCTGCCTGCACTGAAAATATCCCG
ATCAAATGTAACGACGCTTTTTTCCTTGCAGAAAGTATTCGACGATCGCTTTATTCTTGCATCGAACTCTTTTGCCCAGG
AGGTTCTGCTCTTGCGCGCCGATGAATATTCCGGTCTTGATATCAGAACAAACAAGGCTTTTTCCGACAAAAAGCTGCAG
GCGGCTCTTCGGGAGTGGCTCAAAGAGAACGGTATGGAAAGAGGGTTTGTTCTTCGTACTCTTGAACAAAAGTATCGCGA
TATTTTTGCGGTGATGGAGCTTGAGAAGTGGGTGAGTTTCAGCGTGCTCATGCTGGTAATTCTGGTTGCGGCTTTGAGCC
TGACCGGCACCCTTGCCATGACTGCGATCGATAAACAGCGGGAGCTGTTTTATCTGCGCTGTCTGGGGCTTGAAAAACCG
GCATTTATGGCCATTTTTATCATTCAGGGCGGTATGACCGGGGTTTTCGGTACGGCTGCAGGGGCGGCACTTGCCTGGGC
GATCTGCAAAACCCAGGAGCTTTCCGGATTTGTTGAACTTCCGTCGAAAAGCGCGTTTATCATCTCAGCCTATCCTGTGG
AGATGAAAGTCGGCGATTTTGCCATTGTTGCCGTTACCGCTATTGTGCTCTGTCTGCTTGTGAGCCTCTATCCTGCCCGA
AAAGCAGCACAAATCGCAAACAGTAACTCACTTGACGTAAAAGGAGGCTGA

Upstream 100 bases:

>100_bases
TTGTTGACGCTGCTTTTTGCAATTATTCCCGCAAGAATCGCCGCTTCGCTGAAGCCGGGAACAGCTCTCGGATCATGATA
AATCAATACGCGCTCATTTT

Downstream 100 bases:

>100_bases
GCCGGGGATATTCTGTCTGTTGTTTGCATAAAGCAGCGCGTTTAGCTTAAAAGCGCAAACGTTCTCTTGCTCATATTGCA
AACCGGACAGCACCACTCAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MNIALWIARRFSFARKRFRVVNVISAISLAGIIVGVCTLLVVMSVLNGFQKLAWDLFVTLDSPVQIVPKTGRSMTISPQL
LHSIAALQGVSSVEPFLEGEAVLVGSEKSELVMIKGLSEGAHNRLVKVTRSSAPFFTGDNVSVGEQLAYRTELRPFSEIS
LFSPELVAIGLESLSEPYLLPALKISRSNVTTLFSLQKVFDDRFILASNSFAQEVLLLRADEYSGLDIRTNKAFSDKKLQ
AALREWLKENGMERGFVLRTLEQKYRDIFAVMELEKWVSFSVLMLVILVAALSLTGTLAMTAIDKQRELFYLRCLGLEKP
AFMAIFIIQGGMTGVFGTAAGAALAWAICKTQELSGFVELPSKSAFIISAYPVEMKVGDFAIVAVTAIVLCLLVSLYPAR
KAAQIANSNSLDVKGG

Sequences:

>Translated_416_residues
MNIALWIARRFSFARKRFRVVNVISAISLAGIIVGVCTLLVVMSVLNGFQKLAWDLFVTLDSPVQIVPKTGRSMTISPQL
LHSIAALQGVSSVEPFLEGEAVLVGSEKSELVMIKGLSEGAHNRLVKVTRSSAPFFTGDNVSVGEQLAYRTELRPFSEIS
LFSPELVAIGLESLSEPYLLPALKISRSNVTTLFSLQKVFDDRFILASNSFAQEVLLLRADEYSGLDIRTNKAFSDKKLQ
AALREWLKENGMERGFVLRTLEQKYRDIFAVMELEKWVSFSVLMLVILVAALSLTGTLAMTAIDKQRELFYLRCLGLEKP
AFMAIFIIQGGMTGVFGTAAGAALAWAICKTQELSGFVELPSKSAFIISAYPVEMKVGDFAIVAVTAIVLCLLVSLYPAR
KAAQIANSNSLDVKGG
>Mature_416_residues
MNIALWIARRFSFARKRFRVVNVISAISLAGIIVGVCTLLVVMSVLNGFQKLAWDLFVTLDSPVQIVPKTGRSMTISPQL
LHSIAALQGVSSVEPFLEGEAVLVGSEKSELVMIKGLSEGAHNRLVKVTRSSAPFFTGDNVSVGEQLAYRTELRPFSEIS
LFSPELVAIGLESLSEPYLLPALKISRSNVTTLFSLQKVFDDRFILASNSFAQEVLLLRADEYSGLDIRTNKAFSDKKLQ
AALREWLKENGMERGFVLRTLEQKYRDIFAVMELEKWVSFSVLMLVILVAALSLTGTLAMTAIDKQRELFYLRCLGLEKP
AFMAIFIIQGGMTGVFGTAAGAALAWAICKTQELSGFVELPSKSAFIISAYPVEMKVGDFAIVAVTAIVLCLLVSLYPAR
KAAQIANSNSLDVKGG

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=425, Percent_Identity=25.6470588235294, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787360, Length=417, Percent_Identity=23.2613908872902, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45521; Mature: 45521

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIALWIARRFSFARKRFRVVNVISAISLAGIIVGVCTLLVVMSVLNGFQKLAWDLFVTL
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
DSPVQIVPKTGRSMTISPQLLHSIAALQGVSSVEPFLEGEAVLVGSEKSELVMIKGLSEG
CCCEEEEECCCCEEEECHHHHHHHHHHHCCHHCCHHHCCCEEEEECCCCCEEEEEECCCC
AHNRLVKVTRSSAPFFTGDNVSVGEQLAYRTELRPFSEISLFSPELVAIGLESLSEPYLL
CCCCEEEEEECCCCEECCCCCCHHHHHHHHHCCCCCHHHHCCCCHHHEEEHHHCCCCCCC
PALKISRSNVTTLFSLQKVFDDRFILASNSFAQEVLLLRADEYSGLDIRTNKAFSDKKLQ
EEEEECCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHEECCCCCCCEEECCCCCCHHHHH
AALREWLKENGMERGFVLRTLEQKYRDIFAVMELEKWVSFSVLMLVILVAALSLTGTLAM
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAIDKQRELFYLRCLGLEKPAFMAIFIIQGGMTGVFGTAAGAALAWAICKTQELSGFVEL
HHHHHHHHEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEC
PSKSAFIISAYPVEMKVGDFAIVAVTAIVLCLLVSLYPARKAAQIANSNSLDVKGG
CCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEECCCC
>Mature Secondary Structure
MNIALWIARRFSFARKRFRVVNVISAISLAGIIVGVCTLLVVMSVLNGFQKLAWDLFVTL
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
DSPVQIVPKTGRSMTISPQLLHSIAALQGVSSVEPFLEGEAVLVGSEKSELVMIKGLSEG
CCCEEEEECCCCEEEECHHHHHHHHHHHCCHHCCHHHCCCEEEEECCCCCEEEEEECCCC
AHNRLVKVTRSSAPFFTGDNVSVGEQLAYRTELRPFSEISLFSPELVAIGLESLSEPYLL
CCCCEEEEEECCCCEECCCCCCHHHHHHHHHCCCCCHHHHCCCCHHHEEEHHHCCCCCCC
PALKISRSNVTTLFSLQKVFDDRFILASNSFAQEVLLLRADEYSGLDIRTNKAFSDKKLQ
EEEEECCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHEECCCCCCCEEECCCCCCHHHHH
AALREWLKENGMERGFVLRTLEQKYRDIFAVMELEKWVSFSVLMLVILVAALSLTGTLAM
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAIDKQRELFYLRCLGLEKPAFMAIFIIQGGMTGVFGTAAGAALAWAICKTQELSGFVEL
HHHHHHHHEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEC
PSKSAFIISAYPVEMKVGDFAIVAVTAIVLCLLVSLYPARKAAQIANSNSLDVKGG
CCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]