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The map label for this gene is lolC [H]

Identifier: 119357128

GI number: 119357128

Start: 1508684

End: 1509955

Strand: Reverse

Name: lolC [H]

Synonym: Cpha266_1317

Alternate gene names: 119357128

Gene position: 1509955-1508684 (Counterclockwise)

Preceding gene: 119357129

Following gene: 119357127

Centisome position: 48.18

GC content: 47.96

Gene sequence:

>1272_bases
ATGAGGACAGCGTTTTTTATTGCCAGACGTTTTGCATTCAGACAGCGTTCCGGCTCAAAACCGACGTTTATTGTTCTTGC
TTCCGTTATCGGTATTGCCGTCGGAACGGCCGCACTGATTCTTACCCTCTCCATCGTGAACGGGTTTGCTGTCAGCATTG
AAAAAAAACTCATCTCCTTCAGCGCTCATCTTCAGATTCGTCAGTCTGATGACCGCTATTTTGCTGAAACCCGTTCCGAT
CTCAACCTCATAACGAGTCATCCGGAAGTTGAGAGTGCATCGCCGTTTTTTGAGAAAAATCTTATTCTCAAAAGCAAAAG
CGCAACGGATAACGTTGACGTACCAATGGTTAAGCCTGTTGTCCTGAAGGGTATATCGAATATCGAGATGGAGCGTTTTC
TTGAAAATCGGCTTTTGGGCGGTGCTCGGCAGAGCGCAGCGAATGCTGACGCGCTCGGGCTGTATATCGGCAAATCGCTC
GCCGAAAATCTTGCTCTCAAGACCGGCGACAAGGTTTTGCTTATCGGCATGCAGAAAGGAACCATCGAGAACGTCGGCAC
GGATCAGGCCGGTATTCTTGACCTGCTCGCATCTCTTGATCTCGAGTCGGGCACTATTCAGGGTATTTATGATACCGGTC
TGCAGCAGGGTTTTGATGATTTCGTGCTGCTCGGCGACCTTGAAAAAGTTCAGAATCGATTCGGCCCGGGCAAGATCAGC
GGGTATGAGGTGCGTGTTGACAATATCGGCCTTGTCGAAAAAACATCGGAAACGCTGGTGTCGCGTCTCGGGTTTCCGTT
TTTTTCATCAACGGTGTTTCAGCGGTATGCCAATCTGTTTGAATGGCTCAAGCTCCAGAAAAACATCACACCGCTGCTTA
TTGTCACCATCACCGTTGTTGCGGTTTTCAATATTCTTTCGACGATTCTTGTGCTGATCATTGAAAAAACAAGAGAGATC
GGGATGCTTGGAGCCCTTGGCATTGAACCGGGAAAAATCAGCATGATCTTTCTGGGACAGGCTTTTTTTATCGCTTTTAT
CGGGATTGCCGCCGGCAATATCCTGGCGCTTTCGCTCTCGCTGTTTGAAATGCGTTTTCATTTGATCACGCTTCCTGAAA
AAAGTTATTTCATCAAGTATGTTCCCTTGCTCATTGAGCCGATGGACTATTTCATTGTTTCAGCAGCCGTGATGTTGTTG
ACGCTGCTTTTTGCAATTATTCCCGCAAGAATCGCCGCTTCGCTGAAGCCGGGAACAGCTCTCGGATCATGA

Upstream 100 bases:

>100_bases
CCCTTATCAATAATGCCGATCGCGCGCTCTATCACGCAAAAGCCGCCGGAAGAAACATGGTTATCGCATTTTCATCTATT
GATCAGGGGGATAAAACGAC

Downstream 100 bases:

>100_bases
TAAATCAATACGCGCTCATTTTATGAATATCGCTTTATGGATTGCCCGTCGTTTCAGTTTTGCCCGTAAACGATTCAGGG
TTGTCAATGTCATTTCGGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MRTAFFIARRFAFRQRSGSKPTFIVLASVIGIAVGTAALILTLSIVNGFAVSIEKKLISFSAHLQIRQSDDRYFAETRSD
LNLITSHPEVESASPFFEKNLILKSKSATDNVDVPMVKPVVLKGISNIEMERFLENRLLGGARQSAANADALGLYIGKSL
AENLALKTGDKVLLIGMQKGTIENVGTDQAGILDLLASLDLESGTIQGIYDTGLQQGFDDFVLLGDLEKVQNRFGPGKIS
GYEVRVDNIGLVEKTSETLVSRLGFPFFSSTVFQRYANLFEWLKLQKNITPLLIVTITVVAVFNILSTILVLIIEKTREI
GMLGALGIEPGKISMIFLGQAFFIAFIGIAAGNILALSLSLFEMRFHLITLPEKSYFIKYVPLLIEPMDYFIVSAAVMLL
TLLFAIIPARIAASLKPGTALGS

Sequences:

>Translated_423_residues
MRTAFFIARRFAFRQRSGSKPTFIVLASVIGIAVGTAALILTLSIVNGFAVSIEKKLISFSAHLQIRQSDDRYFAETRSD
LNLITSHPEVESASPFFEKNLILKSKSATDNVDVPMVKPVVLKGISNIEMERFLENRLLGGARQSAANADALGLYIGKSL
AENLALKTGDKVLLIGMQKGTIENVGTDQAGILDLLASLDLESGTIQGIYDTGLQQGFDDFVLLGDLEKVQNRFGPGKIS
GYEVRVDNIGLVEKTSETLVSRLGFPFFSSTVFQRYANLFEWLKLQKNITPLLIVTITVVAVFNILSTILVLIIEKTREI
GMLGALGIEPGKISMIFLGQAFFIAFIGIAAGNILALSLSLFEMRFHLITLPEKSYFIKYVPLLIEPMDYFIVSAAVMLL
TLLFAIIPARIAASLKPGTALGS
>Mature_423_residues
MRTAFFIARRFAFRQRSGSKPTFIVLASVIGIAVGTAALILTLSIVNGFAVSIEKKLISFSAHLQIRQSDDRYFAETRSD
LNLITSHPEVESASPFFEKNLILKSKSATDNVDVPMVKPVVLKGISNIEMERFLENRLLGGARQSAANADALGLYIGKSL
AENLALKTGDKVLLIGMQKGTIENVGTDQAGILDLLASLDLESGTIQGIYDTGLQQGFDDFVLLGDLEKVQNRFGPGKIS
GYEVRVDNIGLVEKTSETLVSRLGFPFFSSTVFQRYANLFEWLKLQKNITPLLIVTITVVAVFNILSTILVLIIEKTREI
GMLGALGIEPGKISMIFLGQAFFIAFIGIAAGNILALSLSLFEMRFHLITLPEKSYFIKYVPLLIEPMDYFIVSAAVMLL
TLLFAIIPARIAASLKPGTALGS

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=439, Percent_Identity=25.9681093394077, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787360, Length=425, Percent_Identity=21.8823529411765, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46179; Mature: 46179

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTAFFIARRFAFRQRSGSKPTFIVLASVIGIAVGTAALILTLSIVNGFAVSIEKKLISF
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAHLQIRQSDDRYFAETRSDLNLITSHPEVESASPFFEKNLILKSKSATDNVDVPMVKPV
HHEEEEEECCCHHHHHHCCCCEEEECCCCCCCCCCHHHHCEEEECCCCCCCCCCCCCCHH
VLKGISNIEMERFLENRLLGGARQSAANADALGLYIGKSLAENLALKTGDKVLLIGMQKG
HHHCCCHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
TIENVGTDQAGILDLLASLDLESGTIQGIYDTGLQQGFDDFVLLGDLEKVQNRFGPGKIS
CCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHCCCCCCC
GYEVRVDNIGLVEKTSETLVSRLGFPFFSSTVFQRYANLFEWLKLQKNITPLLIVTITVV
CEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AVFNILSTILVLIIEKTREIGMLGALGIEPGKISMIFLGQAFFIAFIGIAAGNILALSLS
HHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHH
LFEMRFHLITLPEKSYFIKYVPLLIEPMDYFIVSAAVMLLTLLFAIIPARIAASLKPGTA
HHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGS
CCC
>Mature Secondary Structure
MRTAFFIARRFAFRQRSGSKPTFIVLASVIGIAVGTAALILTLSIVNGFAVSIEKKLISF
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAHLQIRQSDDRYFAETRSDLNLITSHPEVESASPFFEKNLILKSKSATDNVDVPMVKPV
HHEEEEEECCCHHHHHHCCCCEEEECCCCCCCCCCHHHHCEEEECCCCCCCCCCCCCCHH
VLKGISNIEMERFLENRLLGGARQSAANADALGLYIGKSLAENLALKTGDKVLLIGMQKG
HHHCCCHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
TIENVGTDQAGILDLLASLDLESGTIQGIYDTGLQQGFDDFVLLGDLEKVQNRFGPGKIS
CCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHCCCCCCC
GYEVRVDNIGLVEKTSETLVSRLGFPFFSSTVFQRYANLFEWLKLQKNITPLLIVTITVV
CEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AVFNILSTILVLIIEKTREIGMLGALGIEPGKISMIFLGQAFFIAFIGIAAGNILALSLS
HHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHH
LFEMRFHLITLPEKSYFIKYVPLLIEPMDYFIVSAAVMLLTLLFAIIPARIAASLKPGTA
HHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]